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51

The Transition from Stem Cell to Progenitor Spermatogonia and Male Fertility Requires the SHP2 Protein Tyrosine Phosphatase

Puri, Pawan, Phillips, Bart T., Suzuki, Hitomi, Orwig, Kyle E., Rajkovic, Aleksandar, Lapinski, Philip E., King, Philip D., Feng, Gen-Sheng, Walker, William H.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

52

Identification of Double-Stranded RNA-Binding Domains in the Interferon-Induced Double-Stranded RNA-Activated p68 Kinase

Gen-sheng Feng, Karen Chong, Aseem Kumar and Bryan R. G. Williams

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 956 KB

english, 1992

53

Hematopoietic Colony Formation from Human Growth Factor-Dependent TF1 Cells and Human Cord Blood Myeloid Progenitor Cells Depends on SHP2 Phosphatase Function

Broxmeyer, Hal E., Etienne-Julan, Maryse, Gotoh, Akihiko, Braun, Stephen E., Lu, Li, Cooper, Scott, Feng, Gen-Sheng, Li, Xing Jun, Chan, Rebecca J.

Journal:

Stem Cells and Development

Year:

2013

Language:

english

File:

PDF, 366 KB

english, 2013

54

Targeted Disruption of Shp2 in Chondrocytes Leads to Metachondromatosis With Multiple Cartilaginous Protrusions

Kim, Harry KW, Feng, Gen-Sheng, Chen, Di, King, Philip D, Kamiya, Nobuhiro

Journal:

Journal of Bone and Mineral Research

Year:

2014

Language:

english

File:

PDF, 4.44 MB

english, 2014

55

Shp2 as a therapeutic target for leptin resistance and obesity

Feng, Gen-Sheng

Journal:

Expert Opinion on Therapeutic Targets

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006

56

Role of SH2-Containing Tyrosine Phosphatase Shp2 in Mouse Corneal Epithelial Stratification

Ng, Gracia Y., Yeh, Lung-Kun, Zhang, Yujin, Liu, HongShan, Feng, Gen-Sheng, Kao, Winston W. Y., Liu, Chia-Yang

Journal:

Investigative Opthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 1.66 MB

english, 2013

57

Protein-tyrosine Phosphatase Shp2 Positively Regulates Macrophage Oxidative Burst

Li, Xing Jun, Goodwin, Charles B, Nabinger, Sarah C., Richine, Briana M., Yang, Zhenyun, Hanenberg, Helmut, Ohnishi, Hiroshi, Matozaki, Takashi, Feng, Gen-Sheng, Chan, Rebecca J.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 3.73 MB

english, 2015

58

The Disturbance of Hippocampal CaMKII/PKA/PKC Phosphorylation in Early Experimental Diabetes Mellitus

Liao, Mei-Hua, Xiang, Ying-Chun, Huang, Ji-Yun, Tao, Rong-Rong, Tian, Yun, Ye, Wei-Feng, Zhang, Gen-Sheng, Lu, Ying-Mei, Ahmed, Muhammad M., Liu, Zhi-Rong, Fukunaga, Kohji, Han, Feng

Journal:

CNS Neuroscience & Therapeutics

Year:

2013

Language:

english

File:

PDF, 900 KB

english, 2013

59

Shp2 Is Dispensable in the Formation and Maintenance of the Neuromuscular Junction

Dong, Xian-Ping, Li, Xiao-Ming, Gao, Tian-Ming, Zhang, Eric E., Feng, Gen-Sheng, Xiong, Wen C., Mei, Lin

Journal:

Year:

2006

Language:

english

File:

PDF, 535 KB

english, 2006

60

Shp2 and Pten have antagonistic roles in myeloproliferation but cooperate to promote erythropoiesis in mammals

Zhu, Helen He, Luo, Xiaolin, Zhang, Kaiqing, Cui, Jian, Zhao, Huifang, Ji, Zhongzhong, Zhou, Zhicheng, Yao, Jufang, Zeng, Lifan, Ji, Kaihong, Gao, Wei-Qiang, Zhang, Zhong-Yin, Feng, Gen-Sheng

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

61

The 64-kDa Protein that Associates with the Platelet-Derived Growth Factor Receptor β Subunit via Tyr-1009 is the SH2-Containing Phosphotyrosine Phosphatase Syp

Andrius Kazlauskas, Gen-Sheng Feng, Tony Pawson and Mindaugas Valius

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.16 MB

english, 1993

62

The dynamic interplay between a PTK (Kit) and a PTP (Shp2) in hematopoietic stem and progenitor cells

Zhu, Helen He, Feng, Gen-Sheng

Journal:

Year:

2011

Language:

english

File:

PDF, 617 KB

english, 2011

63

Treating leukemia at the risk of inducing severe anemia

Chen, Wendy S., Zhu, Helen He, Feng, Gen-Sheng

Journal:

Experimental Hematology

Year:

2016

Language:

english

File:

PDF, 344 KB

english, 2016

64

Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease

Chen, Shuai, Kang, Yujia, Sun, Yan, Zhong, Yanhong, Li, Yanli, Deng, Lijuan, Tao, Jin, Li, Yang, Tian, Yingpu, Zhao, Yinan, Cheng, Jianghong, Liu, Wenjie, Feng, Gen-Sheng, Lu, Zhongxian

Journal:

Journal of Molecular Cell Biology

Year:

2016

Language:

english

File:

PDF, 5.54 MB

english, 2016

65

A new VETC in hepatocellular carcinoma metastasis

Hanley, Kaisa L., Feng, Gen-Sheng

Journal:

Year:

2015

Language:

english

File:

PDF, 419 KB

english, 2015

66

Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway

You, Min, Yu, De-Hua, Feng, Gen-Sheng

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 2.72 MB

english, 1999

67

Biased Suppression of Hematopoiesis and Multiple Developmental Defects in Chimeric Mice Containing Shp-2 Mutant Cells

Qu, Cheng-Kui, Yu, Wen-Mei, Azzarelli, Biagio, Cooper, Scott, Broxmeyer, Hal E., Feng, Gen-Sheng

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

68

SHP2-Deficiency in Chondrocytes Deforms Orofacial Cartilage and Ciliogenesis in Mice

Kamiya, Nobuhiro, Shen, Jingling, Noda, Kazuo, Kitami, Megumi, Feng, Gen-Sheng, Chen, Di, Komatsu, Yoshihiro

Journal:

Journal of Bone and Mineral Research

Year:

2015

Language:

english

File:

PDF, 6.57 MB

english, 2015

69

SHP-2 Phosphatase Prevents Colonic Inflammation by Controlling Secretory Cell Differentiation and Maintaining Host-Microbiota Homeostasis

Coulombe, Geneviève, Langlois, Ariane, De Palma, Giada, Langlois, Marie-Josée, McCarville, Justin L., Gagné-Sanfaçon, Jessica, Perreault, Nathalie, Feng, Gen-Sheng, Bercik, Premysl, Boudreau, François

Journal:

Journal of Cellular Physiology

Year:

2016

Language:

english

File:

PDF, 12.11 MB

english, 2016

70

Characterization of the topology and functional domains of RKTG

Luo, Xiaolin, Feng, Lin, Jiang, Xiaomeng, Xiao, Fei, Wang, Zhenzhen, Feng, Gen-Sheng, Chen, Yan

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 2.23 MB

english, 2008

71

Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor

Mathew, Grinu, Hannan, Abdul, Hertzler-Schaefer, Kristina, Wang, Fen, Feng, Gen-Sheng, Zhong, Jian, Zhao, Jean J., Downward, Julian, Zhang, Xin

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 2.11 MB

english, 2016

72

Effect of the type of brewing water on the chemical composition, sensory quality and antioxidant capacity of Chinese teas

Xu, Yong-Quan, Zou, Chun, Gao, Ying, Chen, Jian-Xin, Wang, Fang, Chen, Gen-Sheng, Yin, Jun-Feng

Journal:

Year:

2016

Language:

english

File:

PDF, 833 KB

english, 2016

73

Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice

Hu, Xiaopeng, Tang, Zhenzhou, Li, Yang, Liu, Wensheng, Zhang, Shuang, Wang, Bingyan, Tian, Yingpu, Zhao, Yinan, Ran, Hao, Liu, Wenjie, Feng, Gen-Sheng, Shuai, Jianwei, Wang, Haibin, Lu, Zhongxian

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 3.42 MB

english, 2015

74

Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase

Ran, Hao, Kong, Shuangbo, Zhang, Shuang, Cheng, Jianghong, Zhou, Chan, He, Bo, Xin, Qiliang, Lydon, John P., DeMayo, Francesco J., Feng, Gen-Sheng, Xia, Guoliang, Lu, Zhongxian, Wang, Chao, Wang, Haib

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

75

Gel-seq: whole-genome and transcriptome sequencing by simultaneous low-input DNA and RNA library preparation using semi-permeable hydrogel barriers

Hoople, Gordon D., Richards, Andrew, Wu, Yan, Kaneko, Kota, Luo, Xiaolin, Feng, Gen-Sheng, Zhang, Kun, Pisano, Albert P.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.91 MB

english, 2017

76

Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways

Cheng, Jianghong, Zhong, Yanhong, Chen, Shuai, Sun, Yan, Huang, Lantang, Kang, Yujia, Chen, Baozhen, Chen, Gang, Wang, Fengli, Tian, Yingpu, Liu, Wenjie, Feng, Gen-Sheng, Lu, Zhongxian

Journal:

The FASEB Journal

Year:

2017

Language:

english

File:

PDF, 5.18 MB

english, 2017

77

Preventive Inhibition of Liver Tumorigenesis by Systemic Activation of Innate Immune Functions

Lee, Jin, Liao, Rui, Wang, Gaowei, Yang, Bi-Huei, Luo, Xiaolin, Varki, Nissi M., Qiu, Shuang-Jian, Ren, Bing, Fu, Wenxian, Feng, Gen-Sheng

Journal:

Year:

2017

Language:

english

File:

PDF, 4.07 MB

english, 2017

78

β-Catenin Deficiency in Hepatocytes Aggravates Hepatocarcinogenesis Driven by Oncogenic β-Catenin and MET

Liang, Yan, Feng, Yun, Zong, Min, Wei, Xufu, Lee, Jin, Feng, Yukuan, Li, Hairi, Yang, Guangshun, Wu, Zhong-Jun, Fu, Xiang-Dong, Feng, Gen-Sheng

Journal:

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

79

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Guo, Wenjie, Liu, Wen, Chen, Zhen, Gu, Yanhong, Peng, Shuang, Shen, Lihong, Shen, Yan, Wang, Xingqi, Feng, Gen-Sheng, Sun, Yang, Xu, Qiang

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 6.53 MB

english, 2017

80

Shp2 Deletion in Hepatocytes Suppresses Hepatocarcinogenesis Driven by Oncogenic β-Catenin, PIK3CA and MET

Liu, Jacey J., Li, Yanjie, Chen, Wendy S., Liang, Yan, Wang, Gaowei, Zong, Min, Kaneko, Kota, Xu, Ruiyun, Karin, Michael, Feng, Gen-Sheng

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 2.80 MB

english, 2018

81

The Unique Cysteine Knot Regulates the Pleotropic Hormone Leptin

Haglund, Ellinor, Sułkowska, Joanna I., He, Zhao, Feng, Gen-Sheng, Jennings, Patricia A., Onuchic, José N., Maya-Monteiro, Clarissa Menezes

Journal:

Year:

2012

Language:

english

File:

PDF, 774 KB

english, 2012

82

Intermittent Cold Exposure Enhances Fat Accumulation in Mice

Yoo, Hyung sun, Qiao, Liping, Bosco, Chris, Leong, Lok-Hei, Lytle, Nikki, Feng, Gen-Sheng, Chi, Nai-Wen, Shao, Jianhua, Waki, Hironori

Journal:

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

83

Macrophage Depletion Disrupts Immune Balance and Energy Homeostasis

Lee, Bonggi, Qiao, Liping, Kinney, Brice, Feng, Gen-Sheng, Shao, Jianhua, Claret, Marc

Journal:

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

84

Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor

Li, Jun, Kang, Yujia, Wei, Longgang, Liu, Wenjie, Tian, Yingpu, Chen, Baozhen, Lin, Xiandong, Li, Yang, Feng, Gen-Sheng, Lu, Zhongxian, Wang, Haibin

Journal:

Year:

2014

Language:

english

File:

PDF, 8.72 MB

english, 2014

85

Crk proteins transduce FGF signaling to promote lens fiber cell elongation

Collins, Tamica N, Mao, Yingyu, Li, Hongge, Bouaziz, Michael, Hong, Angela, Feng, Gen-Sheng, Wang, Fen, Quilliam, Lawrence A, Chen, Lin, Park, Taeju, Curran, Tom, Zhang, Xin

Journal:

Year:

2018

Language:

english

File:

PDF, 8.28 MB

english, 2018

86

Hepatic Autophagy Deficiency Compromises FXR Functionality and Causes Cholestatic Injury

Khambu, Bilon, Li, Tiangang, Yan, Shengmin, Yu, Changshun, Chen, Xiaoyun, Goheen, Michael, Li, Yong, Lin, Jingmei, Cummings, Oscar W., Lee, Youngmin A., Friedman, Scott, Dong, Zheng, Feng, Gen-Sheng,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

87

An Efficient Combination Immunotherapy for Primary Liver Cancer by Harmonized Activation of Innate and Adaptive Immunity

Wen, Liang, Xin, Bing, Wu, Panyisha, Lin, Chia-Hao, Peng, Chuanhui, Wang, Gaowei, Lee, Jin, Lu, Li-Fan, Feng, Gen-Sheng

Journal:

Year:

2019

File:

PDF, 906 KB

2019

88

High-fat feeding reprograms maternal energy metabolism and induces long-term postpartum obesity in mice

Qiao, Liping, Chu, Kayee, Wattez, Jean-Sebastien, Lee, Samuel, Gao, Hongfei, Feng, Gen-Sheng, Hay, William W., Shao, Jianhua

Journal:

International Journal of Obesity

Year:

2019

Language:

english

File:

PDF, 1.73 MB

english, 2019

89

Lens differentiation is controlled by the balance between PDGF and FGF signaling

Li, Hongge, Mao, Yingyu, Bouaziz, Michael, Yu, Honglian, Qu, Xiuxia, Wang, Fen, Feng, Gen-Sheng, Shawber, Carrie, Zhang, Xin, Bronner, Marianne E.

Journal:

Year:

2019

File:

PDF, 13.04 MB

2019

90

Effects of β -Cyclodextrin and Sodium Ascorbate on the Chemical Compositions and Sensory Quality of Instant Green Tea Powder during Storage

Zhang, Yan-Hong, Chen, Gen-Sheng, Chen, Jian-Xin, Liu, Zheng-Quan, Yu, Liao-Yuan, Yin, Jun-Feng, Xu, Yong-Quan

Journal:

Journal of Chemistry

Year:

2019

Language:

english

File:

PDF, 1.50 MB

english, 2019

91

TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

Yang, Bi-Huei, Wang, Ke, Wan, Shuo, Liang, Yan, Yuan, Xiaomei, Dong, Yi, Cho, Sunglim, Xu, Wanqing, Jepsen, Kristen, Feng, Gen-Sheng, Lu, Li-Fan, Xue, Hai-Hui, Fu, Wenxian

Journal:

Year:

2019

Language:

english

File:

PDF, 7.48 MB

english, 2019

92

Stress Conditions Induced by Locoregional Therapies Stimulate Enrichment and Proliferation of Liver Cancer Stem Cells

Huo, Yuchen, Chen, Wendy S., Lee, Jin, Feng, Gen-Sheng, Newton, Isabel G.

Journal:

Journal of Vascular and Interventional Radiology

Year:

2019

Language:

english

File:

PDF, 4.08 MB

english, 2019

93

TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

Yang, Bi-Huei, Wang, Ke, Wan, Shuo, Liang, Yan, Yuan, Xiaomei, Dong, Yi, Cho, Sunglim, Xu, Wanqing, Jepsen, Kristen, Feng, Gen-Sheng, Lu, Li-Fan, Xue, Hai-Hui, Fu, Wenxian

Journal:

Year:

2019

File:

PDF, 7.48 MB

2019

94

A tumorigenic index for quantitative analysis of liver cancer initiation and progression

Wang, Gaowei, Luo, Xiaolin, Liang, Yan, Kaneko, Kota, Li, Hairi, Fu, Xiang-Dong, Feng, Gen-Sheng

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

File:

PDF, 1.62 MB

2019

95

Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development

Qu, Cheng-Kui, Nguyen, Suzanne, Chen, Jianzhu, Feng, Gen-Sheng

Journal:

Year:

2001

File:

PDF, 175 KB

2001

96

Disrupting phosphatase SHP2 in macrophages protects mice from high-fat dietâinduced hepatic steatosis and insulin resistance by elevating IL-18 levels

Liu, Wen, Yin, Ye, Wang, Meijing, Fan, Ting, Zhu, Yuyu, Shen, Lihong, Peng, Shuang, Gao, Jian, Deng, Guoliang, Meng, Xiangbao, Kong, Lingdong, Feng, Gen-Sheng, Guo, Wenjie, Xu, Qiang, Sun, Yang

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 2.57 MB

2020

97

A predictive model for astringency based on in vitro interactions between salivary proteins and (â)-Epigallocatechin gallate

Ye, Qing-Qing, Chen, Gen-Sheng, Pan, Weichun, Cao, Qing-Qing, Zeng, Liang, Yin, Jun-Feng, Xu, Yong-Quan

Journal:

Year:

2021

File:

PDF, 4.68 MB

2021

98

Effect of chemical composition of black tea infusion on the color of milky tea

Mao, Ya-Lin, Wang, Jie-Qiong, Chen, Gen-Sheng, Granato, Daniel, Zhang, Liang, Fu, Yan-Qing, Gao, Ying, Yin, Jun-Feng, Luo, Long-Xin, Xu, Yong-Quan

Journal:

Food Research International

Year:

2020

File:

PDF, 169 KB

2020