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1

Chemie und Biologie von Taxol

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Wei-Min Dai, Rodney Kiplin Guy

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 4.65 MB

german, 1994

2

Chemistry and Biology of Taxol

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Wei-Min Dai, Mr. Rodney Kiplin Guy

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 2.82 MB

english, 1994

3

A Selective Irreversible Inhibitor Targeting a PDZ Protein Interaction Domain

Fujii, Naoaki, Haresco, Jose J., Novak, Kathleen A. P., Stokoe, David, Kuntz, Irwin D., Guy, R. Kiplin

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 125 KB

english, 2003

4

Ein wasserlösliches Prodrug von Taxol mit der Fähigkeit zur Selbstorganisation

Kyriacos Costa Nicolaou, Rodney Kiplin Guy, Prof. Dr. Emmanuel Nicolaou Pitsinos, Wolfgang Wrasidlo

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 822 KB

german, 1994

5

Synthese von C-2-analogen Taxolen

Prof. Dr. Kyriacos Costa Nicolaou, E. A. Couladouros, P. G. Nantermet, J. Renaud, Rodney Kiplin Guy, Wolfgang Wrasidlo

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 365 KB

german, 1994

6

A Metallopeptide Assembly of the HIV-1 gp41 Coiled Coil Is an Ideal Receptor in Fluorescence Detection of Ligand Binding

Miriam Gochin, Rodney Kiplin Guy, Martin A. Case

Journal:

Angewandte Chemie

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

7

Synthesis of C-2 Taxol Analogues

Prof. Dr. Kyriacos Costa Nicolaou, Elias A. Couladouros, Phillipe G. Nantermet, Joanne Renaud, Rodney Kiplin Guy, Wolfgang Wrasidlo

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 331 KB

english, 1994

8

A Water-Soluble Prodrug of Taxol with Self-Assembling Properties

Prof. Dr. Kyriacos Costa Nicolaou, Rodney Kiplin Guy, Emmanuel Nicolauo Pitsinos, Wolfgang Wrasidlo

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 747 KB

english, 1994

9

A Metallopeptide Assembly of the HIV-1 gp41 Coiled Coil Is an Ideal Receptor in Fluorescence Detection of Ligand Binding

Miriam Gochin, Rodney Kiplin Guy, Martin A. Case

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

10

ChemInform Abstract: Copper-Mediated Cross-Coupling of Aryl Boronic Acids and Alkyl Thiols.

Prudencio S. Herradura, Kathleen A. Pendola, R. Kiplin Guy

Journal:

Year:

2000

File:

PDF, 31 KB

2000

11

Synthesis of Medium Ring Heterocycles Using an Intramolecular Heck Reaction.

Leggy A. Arnold, Wenchen Luo, R. Kiplin Guy

Journal:

Year:

2004

File:

PDF, 34 KB

2004

12

A Convenient Procedure for Parallel Ester Hydrolysis.

Marc O. Anderson, Jamie Moser, John Sherrill, R. Kiplin Guy

Journal:

Year:

2005

File:

PDF, 29 KB

2005

13

Discovery of Potent Thiosemicarbazone Inhibitors (V) of Rhodesain and Cruzain.

Naoaki Fujii, Jeremy P. Mallari, Elizabeth J. Hansell, Z. Mackey, Patricia Doyle, Y. M. Zhou, Jiri Gut, Philip J. Rosenthal, James H. McKerrow, R. Kiplin Guy

Journal:

Year:

2005

File:

PDF, 18 KB

2005

14

Synthesis of Ring-Substituted 4-Aminoquinolines and Evaluation of Their Antimalarial Activities.

Peter B. Madrid, John Sherrill, Ally P. Liou, Jennifer L. Weisman, Joseph L. DeRisi, R. Kiplin Guy

Journal:

Year:

2005

Language:

english

File:

PDF, 23 KB

english, 2005

15

Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum

Marc O. Anderson, John Sherrill, Peter B. Madrid, Ally P. Liou, Jennifer L. Weisman, Joseph L. DeRisi, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 423 KB

english, 2006

16

Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy

Luigi Gomez Paloma, R.Kiplin Guy, W. Wrasidlo, K.C. Nicolaou

Journal:

Chemistry & Biology

Year:

1994

Language:

english

File:

PDF, 2.04 MB

english, 1994

17

A road less traveled by: Exploring a decade of Ellman chemistry

Anang A. Shelat, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 202 KB

english, 2009

18

Synthesis and structure–activity relationships of antimalarial 4-oxo-3-carboxyl quinolones

Yiqun Zhang, W. Armand Guiguemde, Martina Sigal, Fangyi Zhu, Michele C. Connelly, Solomon Nwaka, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 858 KB

english, 2010

19

Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models

Jeremy P. Mallari, Fangyi Zhu, Andrew Lemoff, Marcel Kaiser, Min Lu, Reto Brun, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

20

Isotopically labeled crosslinking reagents: resolution of mass degeneracy in the identification of crosslinked peptides

Christopher J. Collins, Birgit Schilling, Malin Young, Gavin Dollinger, R.Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

21

A novel protein crosslinking reagent for the determination of moderate resolution protein structures by mass spectrometry (MS3-D)

Naoaki Fujii, Richard B. Jacobsen, Nichole L. Wood, Joseph S. Schoeniger, R.Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 185 KB

english, 2004

22

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

Naoaki Fujii, Jeremy P. Mallari, Elizabeth J. Hansell, Z. Mackey, Patricia Doyle, Y.M. Zhou, Jiri Gut, Philip J. Rosenthal, James H. McKerrow, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 253 KB

english, 2005

23

Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities

Peter B. Madrid, John Sherrill, Ally P. Liou, Jennifer L. Weisman, Joseph L. DeRisi, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 272 KB

english, 2005

24

Structure–activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells

Barnaby C.H. May, Juanita Witkop, John Sherrill, Marc O. Anderson, Peter B. Madrid, Julie A. Zorn, Stanley B. Prusiner, Fred E. Cohen, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

25

Synthesis of highly substituted dibenzo[b,f]azocines and their evaluation as protein kinase inhibitors

Leggy A. Arnold, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

26

Design of a selective chemical probe for class I PDZ domains

Naoaki Fujii, Anang Shelat, Randy A. Hall, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 338 KB

english, 2007

27

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB

Jeremy P. Mallari, Anang Shelat, Aaron Kosinski, Conor R. Caffrey, Michele Connelly, Fangyi Zhu, James H. McKerrow, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

28

Synthesis and characterization of BODIPY-labeled colchicine

Leggy A. Arnold, Patricia Ranaivo, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

29

Antimalarial activity of thiosemicarbazones and purine derived nitriles

Jeremy P. Mallari, Wendyam A. Guiguemde, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

30

Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis

Jong Yeon Hwang, David Smithson, Michele Connelly, Julie Maier, Fangyi Zhu, Kiplin R. Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

31

Podophyllotoxin analogues active versus Trypanosoma brucei

Md. Jashim Uddin, David C. Smithson, Kristin M. Brown, Brenda C. Crews, Michele Connelly, Fangyi Zhu, Lawrence J. Marnett, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 359 KB

english, 2010

32

The interdependence between screening methods and screening libraries

Anang A Shelat, R Kiplin Guy

Journal:

Current Opinion in Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.13 MB

english, 2007

33

Ligand-Selective Inhibition of the Interaction of Steroid Receptor Coactivators and Estrogen Receptor Isoforms

Timothy R. Geistlinger, Andrea C. McReynolds, R.Kiplin Guy

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 608 KB

english, 2004

34

Synthesis and Testing of a Focused Phenothiazine Library for Binding to HIV-1 TAR RNA

Moriz Mayer, P. Therese Lang, Sabina Gerber, Peter B. Madrid, Irene Gómez Pinto, R. Kiplin Guy, Thomas L. James

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 241 KB

english, 2006

35

Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain

Mark F Springsteel, Luis J.V Galietta, Tonghui Ma, Kolbot By, Gideon O Berger, Hong Yang, Christopher W Dicus, Wonken Choung, Chao Quan, Anang A Shelat, R.Kiplin Guy, A.S Verkman, Mark J Kurth, Michae

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 310 KB

english, 2003

36

Rational design of a nonpeptide general chemical scaffold for reversible inhibition of PDZ domain interactions

Naoaki Fujii, Jose J. Haresco, Kathleen A.P. Novak, Robert M. Gage, Nicoletta Pedemonte, David Stokoe, Irwin D. Kuntz, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 370 KB

english, 2007

37

Investigation of the PDZ domain ligand binding site using chemically modified peptides

Kathleen A.P Novak, Naoaki Fujii, R.Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 118 KB

english, 2002

38

Searching for New Antimalarial Therapeutics amongst Known Drugs

Jennifer L. Weisman, Ally P. Liou, Anang A. Shelat, Fred E. Cohen, R. Kiplin Guy, Joseph L. DeRisi

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

39

Discovery of Trypanocidal Compounds by Whole Cell HTS of Trypanosoma brucei

Zachary B. Mackey, Arthur M. Baca, Jeremy P. Mallari, Beth Apsel, Anang Shelat, Elizabeth J. Hansell, Peter K. Chiang, Brian Wolff, Kiplin R. Guy, Janice Williams, James H. McKerrow

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 554 KB

english, 2006

40

Inhibition of a viral enzyme by a small-molecule dimer disruptor

Shahian, Tina, Lee, Gregory M, Lazic, Ana, Arnold, Leggy A, Velusamy, Priya, Roels, Christina M, Guy, R Kiplin, Craik, Charles S

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 891 KB

english, 2009

41

Scaffold composition and biological relevance of screening libraries

Shelat, Anang A, Guy, R Kiplin

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 5.61 MB

english, 2007

42

Reporting data from high-throughput screening of small-molecule libraries

Inglese, James, Shamu, Caroline E, Guy, R Kiplin

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.50 MB

english, 2007

43

Parallel Synthesis of Diarylureas and Their Evaluation as Inhibitors of Insulin-Like Growth Factor Receptor

Anderson, Marc O., Yu, Hong, Penaranda, Cristina, Maddux, Betty A., Goldfine, Ira D., Youngren, Jack F., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

44

Proteomimetic Libraries: Design, Synthesis, and Evaluation of p53−MDM2 Interaction Inhibitors

Lu, Felice, Chi, Seung-Wook, Kim, Do-Hyoung, Han, Kyou-Hoon, Kuntz, Irwin D., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 333 KB

english, 2006

45

Inhibitors of the Interaction of a Thyroid Hormone Receptor and Coactivators: Preliminary Structure−Activity Relationships

Arnold, Leggy A., Kosinski, Aaron, Estébanez-Perpiñá, Eva, Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

46

Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum: Role of β-haematin inhibition and drug concentration in vacuolar water- and lipid-phases

David C. Warhurst, John C. Craig, Ipemida S. Adagu, R. Kiplin Guy, Peter B. Madrid, Quinton L. Fivelman

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.11 MB

english, 2007

47

MDM2 antagonist nutlin-3a reverses mitoxantrone resistance by inhibiting breast cancer resistance protein mediated drug transport

Fan Zhang, Stacy L. Throm, Laura L. Murley, Laura A. Miller, D. Steven Zatechka Jr., R. Kiplin Guy, Rachel Kennedy, Clinton F. Stewart

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

48

Global Phenotypic Screening for Antimalarials

W. Armand Guiguemde, Anang A. Shelat, Jose F. Garcia-Bustos, Thierry T. Diagana, Francisco-Javier Gamo, R. Kiplin Guy

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

49

An All-Purpose Antimalarial Drug Target

W. Armand Guiguemde, R. Kiplin Guy

Journal:

Cell Host & Microbe

Year:

2012

Language:

english

File:

PDF, 90 KB

english, 2012

50

Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening.

Lack, Nathan A., Axerio-Cilies, Peter, Tavassoli, Peyman, Han, Frank Q., Chan, Ka Hong, Feau, Clementine, LeBlanc, Eric, Guns, Emma Tomlinson, Guy, R. Kiplin, Rennie, Paul S., Cherkasov, Artem

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 523 KB

english, 2011

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