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51

The NFE2-related transcription factor 2 (Nrf2) coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland

Ziros, Panos G, Habeos, Ioannis, Chartoumpekis, Dionysios V, Ntalampyra, Eleni, Somm, Emmanuel, Renaud, Cédric O, Bongiovanni, Massimo, Trougakos, Ioannis P, Yamamoto, Masayuki, Kensler, Thomas W, San

Journal:

Year:

2018

Language:

english

File:

PDF, 2.94 MB

english, 2018

52

Integrating the DNA damage and protein stress responses during cancer development and treatment

Gorgoulis, Vassilis G., Pefani, Dafni-Eleftheria, Pateras, Ioannis S., Trougakos, Ioannis P.

Journal:

The Journal of Pathology

Year:

2018

Language:

english

File:

PDF, 1.74 MB

english, 2018

53

Apolipoprotein J/Clusterin in Human Erythrocytes Is Involved in the Molecular Process of Defected Material Disposal during Vesiculation

Antonelou, Marianna H., Kriebardis, Anastasios G., Stamoulis, Konstantinos E., Trougakos, Ioannis P., Papassideri, Issidora S., Chammas, Roger

Journal:

Year:

2011

Language:

english

File:

PDF, 797 KB

english, 2011

54

Apolipoprotein J/Clusterin Is a Novel Structural Component of Human Erythrocytes and a Biomarker of Cellular Stress and Senescence

Antonelou, Marianna H., Kriebardis, Anastasios G., Stamoulis, Konstantinos E., Trougakos, Ioannis P., Papassideri, Issidora S., Chammas, Roger

Journal:

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

55

Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease

Gumeni, Sentiljana, Trougakos, Ioannis P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2016

Language:

english

File:

PDF, 2.05 MB

english, 2016

56

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

Voutetakis, Konstantinos, Chatziioannou, Aristotelis, Gonos, Efstathios S., Trougakos, Ioannis P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

57

Redox Status and Proteostasis in Ageing and Disease

Rizzi, Federica, Trougakos, Ioannis P., Pintus, Gianfranco, Sykiotis, Gerasimos P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

58

Proteome Stability as a Key Factor of Genome Integrity

Gumeni, Sentiljana, Evangelakou, Zoi, Gorgoulis, Vassilis, Trougakos, Ioannis

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

59

Anti-Melanogenic Properties of Greek Plants. A Novel Depigmenting Agent from Morus alba Wood

Chaita, Eliza, Lambrinidis, George, Cheimonidi, Christina, Agalou, Adamantia, Beis, Dimitris, Trougakos, Ioannis, Mikros, Emmanuel, Skaltsounis, Alexios-Leandros, Aligiannis, Nektarios

Journal:

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017

60

Phytochemical Composition of the Decoctions of Greek Edible Greens (Chórta) and Evaluation of Antioxidant and Cytotoxic Properties

Mikropoulou, Eleni, Vougogiannopoulou, Konstantina, Kalpoutzakis, Eleftherios, Sklirou, Aimilia, Skaperda, Zoi, Houriet, Joëlle, Wolfender, Jean-Luc, Trougakos, Ioannis, Kouretas, Dimitrios, Halabalak

Journal:

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

61

Targeting Protein Quality Control Mechanisms by Natural Products to Promote Healthy Ageing

Wedel, Sophia, Manola, Maria, Cavinato, Maria, Trougakos, Ioannis, Jansen-Dürr, Pidder

Journal:

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

62

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Tsakiri, Eleni N., Gumeni, Sentiljana, Iliaki, Kalliopi K., Benaki, Dimitra, Vougas, Konstantinos, Sykiotis, Gerasimos P., Gorgoulis, Vassilis G., Mikros, Emmanuel, Scorrano, Luca, Trougakos, Ioannis

Journal:

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

63

Comparison survey of EVOO polyphenols and exploration of healthy aging-promoting properties of oleocanthal and oleacein

Nikou, Theodora, Liaki, Vasiliki, Stathopoulos, Panagiotis, Sklirou, Aimilia D., Tsakiri, Eleni N., Jakschitz, Thomas, Bonn, Günther, Trougakos, Ioannis P., Halabalaki, Maria, Skaltsounis, Leandros A.

Journal:

Food and Chemical Toxicology

Year:

2019

File:

PDF, 2.03 MB

2019

64

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

Tsakiri, Eleni N., Gumeni, Sentiljana, Vougas, Konstantinos, Pendin, Diana, Papassideri, Issidora, Daga, Andrea, Gorgoulis, Vassilis, Juhász, Gábor, Scorrano, Luca, Trougakos, Ioannis P.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.91 MB

english, 2019

65

Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach

Evangelakou, Zoi, Manola, Maria, Gumeni, Sentiljana, Trougakos, Ioannis P.

Journal:

Genes & Nutrition

Year:

2019

Language:

english

File:

PDF, 2.39 MB

english, 2019

66

Cercospora sp. as a source of anti-aging polyketides targeting 26S proteasome and scale-up production in submerged bioreactor

Georgousaki, Katerina, Tsafantakis, Nikolaos, Gumeni, Sentiljana, González-Menéndez, Victor, de Pedro, Nuria, Tormo, José Rubén, Almeida, Celso, Lambert, Carole, Genilloud, Olga, Trougakos, Ioannis P.

Journal:

Journal of Biotechnology

Year:

2019

Language:

english

File:

PDF, 1.51 MB

english, 2019

67

Osmanicin, a Polyketide Alkaloid Isolated from Streptomyces osmaniensis CA-244599 Inhibits Elastase in Human Fibroblasts

Samy, Mamdouh N., Le Goff, Géraldine, Lopes, Philippe, Georgousaki, Katerina, Gumeni, Sentiljana, Almeida, Celso, González, Ignacio, Genilloud, Olga, Trougakos, Ioannis, Fokialakis, Nikolas, Ouazzani,

Journal:

Year:

2019

Language:

english

File:

PDF, 2.61 MB

english, 2019

68

What sustains the multidrug resistance phenotype beyond ABC efflux transporters? Looking beyond the tip of the iceberg

Alexa-Stratulat, Teodora, Pešić, Milica, Gašparović, Ana Čipak, Trougakos, Ioannis P., Riganti, Chiara

Journal:

Drug Resistance Updates

Year:

2019

Language:

english

File:

PDF, 2.45 MB

english, 2019

69

Nrf2, stress and aging

Trougakos, Ioannis P.

Journal:

Year:

2019

Language:

english

File:

PDF, 518 KB

english, 2019

70

Nrf2, stress and aging

Trougakos, Ioannis P.

Journal:

Year:

2019

File:

PDF, 518 KB

2019

71

The emergence of drug resistance to targeted therapies: Clinical evidence

Sarmento-Ribeiro, Ana Bela, Scorilas, Andreas, Gonçalves, Ana Cristina, Efferth, Thomas, Trougakos, Ioannis P.

Journal:

Drug Resistance Updates

Year:

2019

Language:

english

File:

PDF, 7.92 MB

english, 2019

72

High Clusterin (CLU) mRNA expression levels in tumors of colorectal cancer patients predict a poor prognostic outcome

Artemaki, Pinelopi I., Sklirou, Aimilia D., Kontos, Christos K., Liosi, Aikaterini-Anna, Gianniou, Despoina D., Papadopoulos, Iordanis N., Trougakos, Ioannis P., Scorilas, Andreas

Journal:

Clinical Biochemistry

Year:

2019

Language:

english

File:

PDF, 544 KB

english, 2019

73

Heat shock protein beta 3 ( HSPB3 ) is an unfavorable molecular biomarker in colorectal adenocarcinoma

Kalioraki, Maria‐Anna, Artemaki, Pinelopi I., Sklirou, Aimilia D., Kontos, Christos K., Adamopoulos, Panagiotis G., Papadopoulos, Iordanis N., Trougakos, Ioannis P., Scorilas, Andreas

Journal:

Molecular Carcinogenesis

Year:

2019

Language:

english

File:

PDF, 1.28 MB

english, 2019

74

Screening for tyrosinase inhibitors from actinomycetes; Identification of trichostatin derivatives from Streptomyces sp. CA-129531 and scale up production in bioreactor

Georgousaki, Katerina, Tsafantakis, Nikolaos, Gumeni, Sentiljana, Gonzalez, Ignacio, Andrew Mackenzie, Thomas, Reyes, Fernando, Lambert, Carole, Trougakos, Ioannis P., Genilloud, Olga, Fokialakis, Nik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 561 KB

2020

75

Inhibition of jasmonate-mediated plant defences by the fungal metabolite higginsianin B

Dallery, Jean-FÃ©lix, Zimmer, Marlene, Halder, Vivek, Suliman, Mohamed, PignÃ©, Sandrine, Le Goff, GÃ©raldine, Gianniou, Despoina D, Trougakos, Ioannis P, Ouazzani, Jamal, Gasperini, Debora, O'Connell

Journal:

Journal of Experimental Botany

Year:

2020

Language:

english

File:

PDF, 1.54 MB

english, 2020

76

Biological Evaluation and In Silico Study of Benzoic Acid Derivatives from Bjerkandera adusta Targeting Proteostasis Network Modules

Georgousaki, Katerina, Tsafantakis, Nikolaos, Gumeni, Sentiljana, Lambrinidis, George, GonzÃ¡lez-MenÃ©ndez, Victor, Tormo, Jose R., Genilloud, Olga, Trougakos, Ioannis P., Fokialakis, Nikolas

Journal:

Year:

2020

File:

PDF, 506 KB

2020

77

Expression profiling meta-analysis of ACE2 and TMPRSS2, the putative anti-inflammatory receptor and priming protease of SARS-CoV-2 in human cells, and identification of putative modulators

Gkogkou, Eirini, Barnasas, Grigoris, Vougas, Konstantinos, Trougakos, Ioannis P.

Journal:

Year:

2020

File:

PDF, 11.39 MB

2020

78

Osirisynes G-I, New Long-Chain Highly Oxygenated Polyacetylenes from the Mayotte Marine Sponge Haliclona sp.

Campos, Pierre-Eric, Herbette, GaÃ«tan, Chendo, Christophe, Clerc, Patricia, Tintillier, Florent, de Voogd, Nicole J., Papanagnou, Eleni-Dimitra, Trougakos, Ioannis P., Jerabek, Moran, Bignon, JÃ©rÃ´m

Journal:

Year:

2020

File:

PDF, 1.95 MB

2020

79

Microorganisms Associated with the Marine Sponge Scopalina hapalia: A Reservoir of Bioactive Molecules to Slow Down the Aging Process

Said Hassane, Charifat, Fouillaud, Mireille, Le Goff, GÃ©raldine, Sklirou, Aimilia D., Boyer, Jean Bernard, Trougakos, Ioannis P., Jerabek, Moran, Bignon, JÃ©rÃ´me, de Voogd, Nicole J., Ouazzani, Jama

Journal:

Year:

2020

File:

PDF, 1.57 MB

2020

80

The Transcriptomic Response of the Murine Thyroid Gland to Iodide Overload and the Role of the Nrf2 Antioxidant System

Chartoumpekis, Dionysios V., Ziros, Panos G., Georgakopoulos-Soares, Ilias, Smith, Adam A. T., Marques, Ana Claudia, Ibberson, Mark, A. Kopp, Peter, Habeos, Ioannis, Trougakos, Ioannis P., Khoo, Nicho

Journal:

Year:

2020

File:

PDF, 5.97 MB

2020