K.S. Koblan: search on Z-Library

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51

Transformed PANSS Factors Intended to Reduce Pseudospecificity Among Symptom Domains and Enhance Understanding of Symptom Change in Antipsychotic-Treated Patients With Schizophrenia

Hopkins, Seth C, Ogirala, Ajay, Loebel, Antony, Koblan, Kenneth S

Journal:

Schizophrenia Bulletin

Year:

2017

Language:

english

File:

PDF, 684 KB

english, 2017

52

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

Koblan, Luke W, Doman, Jordan L, Wilson, Christopher, Levy, Jonathan M, Tay, Tristan, Newby, Gregory A, Maianti, Juan Pablo, Raguram, Aditya, Liu, David R

Journal:

Nature Biotechnology

Year:

2018

Language:

english

File:

PDF, 469 KB

english, 2018

53

Farnesyltransferase inhibitors versus Ras inhibitors

Jackson B Gibbs, Samuel L Graham, George D Hartman, Kenneth S Koblan, Nancy E Kohl, Charles A Omer, Allen Oliff

Journal:

Current Opinion in Chemical Biology

Year:

1997

Language:

english

File:

PDF, 803 KB

english, 1997

54

Absorption, distribution, metabolism, and excretion of [ 14 C]-dasotraline in humans

Chen, Yu-Luan, Skende, Estela, Lin, Jing, Yi, Yijun, Wang, Peter L., Wills, Sarah, Wilkinson, H. Scott, Koblan, Kenneth S., Hopkins, Seth C.

Journal:

Pharmacology Research & Perspectives

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

55

Design and in Vivo Analysis of Potent Non-Thiol Inhibitors of Farnesyl Protein Transferase

Anthony, Neville J., Gomez, Robert P., Schaber, Micheal D., Mosser, Scott D., Hamilton, Kelly A., O'Neil, Timothy J., Koblan, Kenneth S., Graham, Samuel L., Hartman, George D., Shah, Daksha, Rands, El

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

56

DIARYLETHER INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Christopher J Dinsmore*, Theresa M Williams, Kelly Hamilton, Timothy J O'Neill, Elaine Rands, Kenneth S Koblan, Nancy E Kohl, Jackson B Gibbs, Samuel L Graham, George D Hartman, Allen I Oliff

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 552 KB

english, 1997

57

Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel

Jerzy Karczewski, Jixin Wang, Stefanie A. Kane, Laszlo Kiss, Kenneth S. Koblan, J. Christopher Culberson, Robert H. Spencer

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 663 KB

english, 2009

58

Identification and Pharmacological Characterization of Domains Involved in Binding of CGRP Receptor Antagonists to the Calcitonin-like Receptor

Salvatore, Christopher A., Mallee, John J., Bell, Ian M., Zartman, C. Blair, Williams, Theresa M., Koblan, Kenneth S., Kane, Stefanie A.

Journal:

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

59

Dasotraline for the Treatment of Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled, Proof-of-Concept Trial in Adults

Koblan, Kenneth S, Hopkins, Seth C, Sarma, Kaushik, Jin, Fengbin, Goldman, Robert, Kollins, Scott H, Loebel, Antony

Journal:

Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 3.38 MB

english, 2015

60

NMR studies of novel inhibitors bound to farnesyl-protein transferase

Kenneth S. Koblan, Scott D. Mosser, Charles A. Omer, J. Christopher Culberson, S. Jane Desolms, Elizabeth A. Giuliani, Steven M. Pitzenberger, Michael J. Bogusky

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 4.31 MB

english, 1995

61

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

Beck, Andreas, Nadler, Monica J. S., Koblan-Huberson, Murielle, Lis, Annette, Fleig, Andrea, Penner, Reinhold, Kinet, Jean-Pierre, Peinelt, Christine, Vig, Monika, Koomoa, Dana L.

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 467 KB

english, 2006

62

Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells

Lars Edvinsson, Rikard Alm, Duncan Shaw, Ruth Z Rutledge, Kenneth S Koblan, Jenny Longmore, Stefanie A Kane

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 112 KB

english, 2002

63

6.15 Dasotraline Efficacy Throughout the Day in Children With Attention-Deficit/Hyperactivity Disorder (ADHD): Results of a Phase Three, Randomized, Double-Blind, Placebo-Controlled Study in a Laboratory Classroom Setting

Goldman, Robert, Childress, Ann, Wigal, Sharon B., Hopkins, Seth C., Koblan, Kenneth S., Sarma, Kaushik, Wan, Xiaohai, Loebel, Antony

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

2017

Language:

english

File:

PDF, 111 KB

english, 2017

64

Effect of the inflammatory biomarker C-reactive protein on response to lurasidone treatment in patients with bipolar depression

Pikalov, A., Raison, C., Siu, C., Tsai, J., Koblan, K., Loebel, A.

Journal:

European Neuropsychopharmacology

Year:

2017

Language:

english

File:

PDF, 64 KB

english, 2017

65

Quantitative study of protein association at picomolar concentrations: The λ phage cl repressor

Dorothy Beckett, Kenneth S. Koblan, Gary K. Ackers

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 798 KB

english, 1991

66

Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat

K. R. Oliver, S. A. Kane, C. A. Salvatore, J. J. Mallee, A. M. Kinsey, K. S. Koblan, N. Keyvan-Fouladi, R. P. Heavens, A. Wainwright, M. Jacobson, I. M. Dickerson, R. G. Hill

Journal:

European Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 567 KB

english, 2001

67

Chronic Neuropathic Pain is Accompanied by Global Changes in Gene Expression and Shares Pathobiology with Neurodegenerative Diseases

H Wang, H Sun, K Della Penna, RJ Benz, J Xu, DL Gerhold, DJ Holder, KS Koblan

Journal:

Journal of the Peripheral Nervous System

Year:

2003

Language:

english

File:

PDF, 62 KB

english, 2003

68

Effects of the prototype serotonin 5-HT1B/1D receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP8–37 on myocardial reactive hyperemic response in conscious dogs

Joseph J. Lynch, You-Tang Shen, Tamara J. Pittman, Kenneth D. Anderson, Kenneth S. Koblan, Robert J. Gould, Christopher P. Regan, Stefanie A. Kane

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 389 KB

english, 2009

69

Assessment of human abuse potential of dasotraline compared to methylphenidate and placebo in recreational stimulant users

Koblan, Kenneth S., Hopkins, Seth S., Sarma, Kaushik, senmartin, Nadia, Levy-Cooperman, Naama, Schoedel, Kerri, Loebel, Antony

Journal:

Drug and Alcohol Dependence

Year:

2015

Language:

english

File:

PDF, 56 KB

english, 2015

70

Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET

Koblan, Luke W., Buckley, Dennis L., Ott, Christopher J., Fitzgerald, Mark E., Ember, Stuart W. J., Zhu, Jin-Yi, Liu, Shuai, Roberts, Justin M., Remillard, David, Vittori, Sarah, Zhang, Wei, Schonbrun

Journal:

Year:

2016

Language:

english

File:

PDF, 845 KB

english, 2016

71

Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity

Thuronyi, Benjamin W., Koblan, Luke W., Levy, Jonathan M., Yeh, Wei-Hsi, Zheng, Christine, Newby, Gregory A., Wilson, Christopher, Bhaumik, Mantu, Shubina-Oleinik, Olga, Holt, Jeffrey R., Liu, David R

Journal:

Nature Biotechnology

Year:

2019

File:

PDF, 481 KB

2019

72

Automated Sleep Scoring with Human Supervision Adds Value Compared with Human Scoring Alone: A reply to Zammit G. K. Insufficient evidence for the use of automated and semi-automated scoring of polysomnographic recordings. SLEEP 2008:31;449–50

Svetnik, Vladimir, Ma, Junshui, Soper, Keith A., Doran, Scott, Renger, John J., Deacon, Steve, Koblan, Ken S.

Journal:

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

73

A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity

Bachovchin, Daniel A, Koblan, Luke W, Wu, Wengen, Liu, Yuxin, Li, Youhua, Zhao, Peng, Woznica, Iwona, Shu, Ying, Lai, Jack H, Poplawski, Sarah E, Kiritsy, Christopher P, Healey, Sarah E, DiMare, Matth

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.96 MB

english, 2014

74

Cooperative protein-DNA interactions: effects of potassium chloride on .lambda. cI binding to OR

Koblan, Kenneth S., Ackers, Gary K.

Journal:

Year:

1991

Language:

english

File:

PDF, 761 KB

english, 1991

75

Assessment of human abuse potential of dasotraline compared to methylphenidate and placebo in recreational stimulant users

Koblan, K.S., Hopkins, S.C., Sarma, K., Gallina, N., Jin, F., Levy-Cooperman, N., Schoedel, K.A., Loebel, A.

Journal:

Drug and Alcohol Dependence

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

76

Functional neuroimaging study of a new compound for schizophrenia in healthy volunteers with high or low schizotypy

Perini, F., Nazimek, J., Browning, M., Dawson, G., Nishikawa, H., Campbell, U., Hopkins, S., Loebel, A., Koblan, K., Deakin, J.F.W.

Journal:

European Neuropsychopharmacology

Year:

2017

Language:

english

File:

PDF, 51 KB

english, 2017

77

Functional and pharmacological properties of canine ERG potassium channels

Wang, Jixin, Della Penna, Kimberly, Wang, Hao, Karczewski, Jerzy, Connolly, Thomas M., Koblan, Kenneth S., Bennett, Paul B., Salata, Joseph J.

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

2003

File:

PDF, 317 KB

2003

78

Automation of In Vitro Dose-Inhibition Assays Utilizing the Tecan Genesis and an Integrated Software Package to Support the Drug Discovery Process

Mosser, Scott D., Gaul, Stanley L., Bednar, Bohumil, Koblan, Kenneth S., Bednar, Rodney A., Bednar, Rodney A.

Journal:

Journal of the Association for Laboratory Automation

Year:

2003

Language:

english

File:

PDF, 1.93 MB

english, 2003

79

Efficacy and Safety of Dasotraline in Children With ADHD: A Laboratory Classroom Study

Wigal, Sharon B., Hopkins, Seth C., Koblan, Kenneth S., Childress, Ann, Kent, Justine M., Tsai, Joyce, Hsu, Jay, Loebel, Antony, Goldman, Robert

Journal:

Journal of Attention Disorders

Year:

2019

File:

PDF, 3.49 MB

2019

80

T109. CLUSTERING OF SCHIZOPHRENIA PATIENT SUBTYPES BY SPECIFIC SYMPTOM DIMENSIONS USING AN UNCORRELATED PANSS SCORE MATRIX (UPSM)

Hopkins, Seth, Origala, Ajay, Loebel, Antony, Koblan, Kenneth S

Journal:

Schizophrenia Bulletin

Year:

2018

Language:

english

File:

PDF, 78 KB

english, 2018

81

Oxo-piperazine Derivatives of N-Arylpiperazinones as Inhibitors of Farnesyltransferase

Christopher J Dinsmore, Jeffrey M Bergman, Donna D Wei, C.Blair Zartman, Joseph P Davide, Ian B Greenberg, Dongming Liu, Timothy J O'Neill, Jackson B Gibbs, Kenneth S Koblan, Nancy E Kohl, Robert B Lo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 144 KB

english, 2001

82

Catechol-O-methyltransferase genotype as modifier of superior responses to venlafaxine treatment in major depressive disorder

Hopkins, Seth C., Reasner, David S., Koblan, Kenneth S.

Journal:

Psychiatry Research

Year:

2013

Language:

english

File:

PDF, 389 KB

english, 2013

83

High-Performance Liquid Chromatography/Mass Spectrometry Characterization of Ki4B-Ras in PSN-1 Cells Treated with the Prenyltransferase Inhibitor L-778,123

Carolyn A. Buser, Christopher J. Dinsmore, Christine Fernandes, Ian Greenberg, Kelly Hamilton, Scott D. Mosser, Eileen S. Walsh, Theresa M. Williams, Kenneth S. Koblan

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 179 KB

english, 2001

84

src -homology 2 (SH2) domain ligation as an allosteric regulator: modulation of phosphoinositide-specific phospholipase C γ 1 structure and activity

Koblan, K S, Schaber, M D, Edwards, G, Gibbs, J B, Pompliano, D L

Journal:

Biochemical Journal

Year:

1995

Language:

english

File:

PDF, 1.41 MB

english, 1995

85

179 Dasotraline in Children With Attention Deficit Hyperactivity Disorder: Results of a Randomized, Double-Blind, Placebo-Controlled Study

Goldman, Robert, Adler, Lenard, Spencer, Thomas, Findling, Robert, Hopkins, Seth C., Koblan, Kenneth K., Sarma, Kaushik, Hsu, Jay, Loebel, Antony

Journal:

Year:

2018

File:

PDF, 81 KB

2018

86

High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

Bessen, Jeffrey L., Afeyan, Lena K., Dančík, Vlado, Koblan, Luke W., Thompson, David B., Leichner, Chas, Clemons, Paul A., Liu, David R.

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.24 MB

english, 2019

87

Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

Bessen, Jeffrey L., Afeyan, Lena K., Dančík, Vlado, Koblan, Luke W., Thompson, David B., Leichner, Chas, Clemons, Paul A., Liu, David R.

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 522 KB

english, 2019

88

Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase

Christopher J. Dinsmore, Theresa M. Williams, Timothy J. O'Neill, Dongming Liu, Elaine Rands, J.Christopher Culberson, Robert B. Lobell, Kenneth S. Koblan, Nancy E. Kohl, Jackson B. Gibbs, Allen I. Ol

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 379 KB

english, 1999

89

Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase

Terrence M. Ciccarone, Suzanne C. MacTough, Theresa M. Williams, Christopher J. Dinsmore, Timothy J. O'Neill, Daksha Shah, J.Christopher Culberson, Kenneth S. Koblan, Nancy E. Kohl, Jackson B. Gibbs,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 408 KB

english, 1999

90

Differential Roles of CB1 and CB2 Cannabinoid Receptors in Mast Cells

Samson, M.-T., Small-Howard, A., Shimoda, L. M. N., Koblan-Huberson, M., Stokes, A. J., Turner, H.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 387 KB

english, 2003

91

Pharmacokinetics and Exposure-Response Relationships of Dasotraline in the Treatment of Attention-Deficit/Hyperactivity Disorder in Adults

Hopkins, Seth C., Sunkaraneni, Soujanya, Skende, Estela, Hing, Jeremy, Passarell, Julie A., Loebel, Antony, Koblan, Kenneth S.

Journal:

Clinical Drug Investigation

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

92

T-type calcium channels regulate cortical plasticity in-vivo NR-D-08-7049

Uebele, Victor N., Nuss, Cindy E., Santarelli, Vincent P., Garson, Susan L., Barrow, James C., Stauffer, Shaun R., Koblan, Kenneth S., Renger, John J., Aton, Sara, Seibt, Julie, Dumoulin, Michelle, Jh

Journal:

Year:

2009

Language:

english

File:

PDF, 169 KB

english, 2009

93

Author Correction: Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

Richter, Michelle F., Zhao, Kevin T., Eton, Elliot, Lapinaite, Audrone, Newby, Gregory A., Thuronyi, Benjamin W., Wilson, Christopher, Koblan, Luke W., Zeng, Jing, Bauer, Daniel E., Doudna, Jennifer A

Journal:

Nature Biotechnology

Year:

2020

File:

PDF, 494 KB

2020

94

In vitro characterization of novel NR2B selective NMDA receptor antagonists

Laszlo Kiss, Gong Cheng, Bohumil Bednar, Rodney A. Bednar, Paul B. Bennett, Stefanie A. Kane, Charles J. McIntyre, John A. McCauley, Kenneth S. Koblan

Journal:

Neurochemistry International

Year:

2005

Language:

english

File:

PDF, 478 KB

english, 2005

95

Investigation of the species selectivity of a nonpeptide CGRP receptor antagonist using a novel pharmacodynamic assay

James C. Hershey, Halea A. Corcoran, Elizabeth P. Baskin, Christopher A. Salvatore, Scott Mosser, Theresa M. Williams, Kenneth S. Koblan, Richard J. Hargreaves, Stefanie A. Kane

Journal:

Regulatory Peptides

Year:

2005

Language:

english

File:

PDF, 387 KB

english, 2005

96

Site-specific enthalpic regulation of DNA transcription at bacteriophage .lambda. OR

Koblan, Kenneth S., Ackers, Gary K.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.73 MB

english, 1992

97

Localization of a Binding Site for Phosphatidylinositol 4,5-Bisphosphate on Human Profilin

Sohn, R. H., Chen, J., Koblan, K. S., Bray, P. F., Goldschmidt-Clermont, P. J.

Journal:

Journal of Biological Chemistry

Year:

1995

Language:

english

File:

PDF, 667 KB

english, 1995

98

6.16 Dasotraline in Children With Attention-Deficit/Hyperactivity Disorder (ADHD): Results of a Randomized, Double-Blind, Placebo-Controlled Study

Goldman, Robert, Adler, Lenard, Spencer, Thomas J., Findling, Robert, Hopkins, Seth C., Koblan, Kenneth S., Sarma, Kaushik, Wan, Xiaohai, Loebel, Antony

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

2017

Language:

english

File:

PDF, 111 KB

english, 2017

99

Tuberoinfundibular peptide of 39 residues (TIP39): molecular structure and activity for parathyroid hormone 2 receptor

K. Della Penna, F. Kinose, H. Sun, K.S. Koblan, H. Wang

Journal:

Neuropharmacology

Year:

2003

Language:

english

File:

PDF, 274 KB

english, 2003

100

Rheological characterization of poly(ethylene oxide) solutions of different molecular weights

Koblan Wilfried Ebagninin, Adel Benchabane, Karim Bekkour

Journal:

Journal of Colloid and Interface Science

Year:

2009

Language:

english

File:

PDF, 763 KB

english, 2009

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