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51

Effect of α1-adrenoceptor stimulation with methoxamine and phenylephrine on spontaneously beating rabbit sino-atrial node cells

Hiroyasu Satoh, Keitaro Hashimoto

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1988

Language:

english

File:

PDF, 728 KB

english, 1988

52

Electrophysiological actions of A23187 and X-537A in spontaneously beating and in voltage-clamped rabbit sino-atrial node preparations

Hiroyasu Satoh, Katsuharu Tsuchida, Keitaro Hashimoto

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1989

Language:

english

File:

PDF, 762 KB

english, 1989

53

A unique pressor response to isoprenaline in the pithed rat during triiodo-l-thyronine (T3)-induced hyperthyroidism

Gozoh Tsujimoto, Keitaro Hashimoto

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1986

Language:

english

File:

PDF, 786 KB

english, 1986

54

The relation between the current underlying pacemaker activity and beta-adrenoceptors in cardiac Purkinje fibres: A study using adrenaline, procaine, atenolol and penbutolol

Keitaro Hashimoto, Otto Hauswirth, Heinz D. Wehner, Rolf Ziskoven

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1979

Language:

english

File:

PDF, 985 KB

english, 1979

55

An electrophysiological study of amiloride on sino-atrial node cells and ventricular muscle of rabbit and dog

Hirovasu Satoh, Keitaro Hashimoto

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1986

Language:

english

File:

PDF, 854 KB

english, 1986

56

Distribution and developmental change of vasopressin V1A and V2 receptor mRNA in rats

Akira Hirasawa, Keitaro Hashimoto, Gozoh Tsujimoto

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 502 KB

english, 1994

57

In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome

Katsuyoshi Chiba, Atsushi Sugiyama, Takehiro Hagiwara, Shin-ichi Takahashi, Kiyoshi Takasuna, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 413 KB

english, 2004

58

Comparison of sensitivity of surrogate markers of drug-induced torsades de pointes in canine hearts

Katsuyoshi Chiba, Atsushi Sugiyama, Kiyoshi Takasuna, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 145 KB

english, 2004

59

Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs

Yoshinobu Nagasawa, Bing-Mei Zhu, Jianguang Chen, Kazunori Kamiya, Shigeki Miyamoto, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

60

Halothane sensitizes the canine heart to pharmacological IKr blockade

Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Kai Wang, Sachiko Honsho, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 276 KB

english, 2005

61

Analysis of proarrhythmic potential of antipsychotics risperidone and olanzapine in anesthetized dogs

Kentaro Ando, Atsushi Sugiyama, Akira Takahara, Yoshioki Satoh, Tomomichi Ishizaka, Yuji Nakamura, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 810 KB

english, 2007

62

Torsades de pointes liability inter-model comparisons: The experience of the QT PRODACT initiative

Keitaro Hashimoto

Journal:

Pharmacology & Therapeutics

Year:

2008

Language:

english

File:

PDF, 144 KB

english, 2008

63

Effects of arsenic trioxide, an inhibitor for hERG channel trafficking, on the electrocardiogram of the guinea pig

Mototsugu Sakakibara, Atsushi Sasaki, Yoshikazu Tsumura, Keitaro Hashimoto, Yasushi Yamashita

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

64

Protective effect of γ-glutamylcysteinylethyl ester on dysfunction of the selenium-deficient rat heart

Tadashi Okamoto, Keiichi Mizuta, Takayuki Takahashi, Takeo Kishi, Shigehisa Kitahara, Sadayoshi Komori, Keitaro Hashimoto, Kiyota Goshima

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 320 KB

english, 1999

65

Antiarrhythmic and cardiohemodynamic effects of a novel Ca2+ channel blocker, AH-1058, assessed in canine arrhythmia models

Akira Takahara, Atsushi Sugiyama, Hideki Dohmoto, Ryota Yoshimoto, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

66

QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide

Shigeki Miyamoto, Bing-Mei Zhu, Tsuyoshi Teramatsu, Nu Nu Aye, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 165 KB

english, 2000

67

Cardiovascular action of a cardioselective Ca2+channel blocker AH-1058 in conscious dogs assessed by telemetry

Akira Takahara, Hideki Dohmoto, Ryota Yoshimoto, Atsushi Sugiyama, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 460 KB

english, 2001

68

Does Cl−/HCO3− exchange play an important role in reperfusion arrhythmias in rats?

Bing-Mei Zhu, Shigeki Miyamoto, Yoshinobu Nagasawa, Masaki Saitoh, Sadayoshi Komori, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

69

Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model

Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Masahiko Yoneyama, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

70

Famotidine does not induce long QT syndrome: experimental evidence from in vitro and in vivo test systems

Atsushi Sugiyama, Yoshioki Satoh, Akira Takahara, Yuji Nakamura, Masao Shimizu-Sasamata, Shuichi Sato, Keiji Miyata, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 312 KB

english, 2003

71

Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models

YiXue Xue, Chikaomi Yamada, Daisuke Chino, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 240 KB

english, 1999

72

Effects of zatebradine and propranolol on canine ischemia and reperfusion-induced arrhythmias

Hisaya Naito, Yasuyuki Furukawa, Daisuke Chino, Chikaomi Yamada, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

73

IK independent class III actions of MS-551 compared with sematilide and dofetilide during reperfusion in anaesthetized rats

Jianguang Chen, Sadayoshi Komori, Binghong Li, Kohji Tamura, Keitaro Hashimoto

Journal:

British Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.22 MB

english, 1996

74

Cardiac irregularities induced by intracoronary injection of epinephrine and acetylcholine into various portions of the canine ventricle

Keitaro Hashimoto, Koroku Hashimoto

Journal:

American Heart Journal

Year:

1972

Language:

english

File:

PDF, 731 KB

english, 1972

75

The mechanism of sensitization of the ventricle to epinephrine by halothane

Keitaro Hashimoto, Koroku Hashimoto

Journal:

American Heart Journal

Year:

1972

Language:

english

File:

PDF, 558 KB

english, 1972

76

Effect of propafenone on the membrane currents of rabbit sino-atrial node cells

Hiroyasu Satoh, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 402 KB

english, 1984

77

Electrophysiological study of alinidine in voltage clamped rabbit sino-atrial node cells

Hiroyasu Satoh, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 543 KB

english, 1986

78

Comparative effects of a new calcium channel antagonist, mepirodipine, on rabbit spontaneously beating sino-atrial node cells

Hiroyasu Satoh, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 425 KB

english, 1991

79

Effects of gallopamil, a Ca2+ channel blocker in models of ventricular arrhythmia in dogs

Takushi Matsuzaki, Akihiro Haruno, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 619 KB

english, 1993

80

Antiarrhythmic effects of bisaramil in canine models of ventricular arrhythmia

Akihiro Haruno, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 489 KB

english, 1993

81

Effects of MCI-154, a new cardiotonic Ca2+ sensitizer, on ventricular arrhythmias and membrane ionic currents

Koji Eto, Yi xue Xue, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1015 KB

english, 1996

82

Effects of zatebradine on ouabain-, two-stage coronary ligation- and epinephrine-induced ventricular tachyarrhythmias

Yasuyuki Furukawa, Yi-xue Xue, Shigetoshi Chiba, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 806 KB

english, 1996

83

Effects of yutac on new in vivo canine triggered activity arrhythmia models

Akihiro Haruno, Keitaro Hashimoto

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1990

Language:

english

File:

PDF, 93 KB

english, 1990

84

Electrophysiological characteristics of MS-551, a class III antiarrhythmic agent using canine purkinje fibers

Keitaro Hashimoto, Masaaki Ishii, Joji Kamiya

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1990

Language:

english

File:

PDF, 105 KB

english, 1990

85

Comparative efficacy of different types of antiarrhythmic drugs

Keitaro Hashimoto

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 105 KB

english, 1992

86

Negative dromotropic effects of mannitol are due to increases in extracellular space of the atrioventricular conduction system

Shigeru Motomura, Keith G Lurie, Keitaro Hashimoto

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 114 KB

english, 1992

87

Enhancement of antitumor activity of OK-432 (Picibanil) by Triton X-114 phase partitioning

Masahito Hashimoto, Katsuhiro Takashige, Maiko Furuyashiki, Keitaro Yoshidome, Ryoko Sano, Yutaka Kawamura, Shinji Ijichi, Hirofumi Morioka, Hiroyuki Koide, Naoto Oku, Yoichiro Moriya, Shoich Kusumoto

Journal:

International Immunopharmacology

Year:

2008

Language:

english

File:

PDF, 668 KB

english, 2008

88

Inhibitory effect on the tobacco mosaic virus infection by a plant RING finger protein

Yasuyuki Yamaji, Koji Hamada, Toshio Yoshinuma, Keitaro Sakurai, Atsushi Yoshii, Takumi Shimizu, Masayoshi Hashimoto, Masashi Suzuki, Shigetou Namba, Tadaaki Hibi

Journal:

Year:

2010

Language:

english

File:

PDF, 941 KB

english, 2010

89

Key amino acids for differential coupling of α1-adrenergic receptor subtypes to Gs

Hitomi Shinoura, Katsushi Shibata, Akira Hirasawa, Akito Tanoue, Keitaro Hashimoto, Gozoh Tsujimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 357 KB

english, 2002

90

Antiarrhythmic effects of HOE642, a novel Na+-H+ exchange inhibitor, on ventricular arrhythmias in animal hearts

Yi Xue Xue, Nu Nu Aye, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 126 KB

english, 1996

91

Antiarrhythmic effects of an aconitine-like compound, TJN-505, on canine arrhythmia models

Jiro Arita, Yi Xue Xue, Nu Nu Aye, Kiyoshi Fukuyama, Yoko Wakui, Kazuaki Niitsu, Masao Maruno, Chen Siying, Keitaro Hashimoto

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 726 KB

english, 1996

92

Corrigendum to: Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC-21268 (FEBS 23227): [FEBS Letters 466 (2000) 255–258]

Hitomi Shinoura, Hitoshi Take, Shuji Itoh, Akira Hirasawa, Kazuhide Inoue, Yasuo Ohno, Keitaro Hashimoto, Gozoh Tsujimoto

Journal:

Year:

2000

Language:

english

File:

PDF, 25 KB

english, 2000

93

S1-5 Pharmacological approach to reduce ischemia/reperfusion ventricular arrhythmias

Keitaro Hashimoto, Bingmei Zhu, Yoshinobu Nagasawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 193 KB

english, 2002

94

Difference of the nuclear ploidy levels between atrial and ventricular myocyte isolated from adult guinea -pig heart

Nobuo Homma, Md.Shah Amran, Keitaro Hashimoto

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

95

Differences in the subcellular localization of α1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin

Tatsuo Sugawara, Akira Hirasawa, Keitaro Hashimoto, Gozoh Tsujimoto

Journal:

Year:

2002

Language:

english

File:

PDF, 464 KB

english, 2002

96

Acute cardiovascular effects of a new beverage made of wine vinegar and grape juice, assessed using an in vivo rat

Atsushi Sugiyama, Masaki Saitoh, Akira Takahara, Yoshioki Satoh, Keitaro Hashimoto

Journal:

Nutrition Research

Year:

2003

Language:

english

File:

PDF, 95 KB

english, 2003

97

L- plus N- type Ca2+ channel blocker cilnidipine reduced arrhythmogenic substrates in the canine sudden cardiac death model with hypertension

Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Yuji Nakamura, Tomoyuki Konda, Keitaro Hashimoto

Journal:

American Journal of Hypertension

Year:

2003

Language:

english

File:

PDF, 35 KB

english, 2003

98

Effects of OPC-8212, a new positive inotropic agent, on canine ventricular arrhythmias

Keitaro Hashimoto, Harumi Mitsuhashi

Journal:

British Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 797 KB

english, 1986

99

An electrophysiological comparison of a novel class Ic antiarrhythmic agent, NIK-244 (ethacizin) and flecainide in canine ventricular muscle

Hiroyasu Satoh, Masaaki Ishii, Keitaro Hashimoto

Journal:

British Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 754 KB

english, 1989

100

Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC-21268

Hitomi Shinoura, Hitoshi Take, Akira Hirasawa, Kazuhide Inoue, Yasuo Ohno, Keitaro Hashimoto, Gozoh Tsujimoto

Journal:

Year:

2000

Language:

english

File:

PDF, 105 KB

english, 2000