L. M. Aleksunes: search on Z-Library

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1

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

Klaassen, C. D., Aleksunes, L. M.

Journal:

Pharmacological Reviews

Year:

2010

Language:

english

File:

PDF, 6.82 MB

english, 2010

2

Management of Rosiglitazone-Induced Edema: Two Case Reports and a Review of the Literature

Wang, Fei, Aleksunes, Lauren M., Reagan, Louise A., Vergara, Cunegundo M.

Journal:

Diabetes Technology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

3

Renal and Hepatic Transporter Expression in Type 2 Diabetic Rats

Manautou, Jose, Nowicki, Michael, Aleksunes, Lauren, Sawant, Sharmilee, Dnyanmote, Ankur, Mehendale, Harihara

Journal:

Drug Metabolism Letters

Year:

2008

Language:

english

File:

PDF, 661 KB

english, 2008

4

Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064

Moscovitz, Jamie E., Kong, Bo, Buckley, Kyle, Buckley, Brian, Guo, Grace L., Aleksunes, Lauren M.

Journal:

Toxicology and Applied Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

5

Interindividual regulation of the BCRP/ABCG2 transporter in term human placentas

Bircsak, Kristin M, Moscovitz, Jamie E, Wen, Xia, Archer, Faith, Yuen, Poi Yu Sofia, Mohammed, Moiz, Memon, Naureen, Weinberger, Barry I, Saba, Laura M, Vetrano, Anna M, Aleksunes, Lauren M

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 491 KB

english, 2018

6

Pharmacokinetic determinants of cisplatin-induced subclinical kidney injury in oncology patients

Ibrahim, Mustafa E., Chang, Cara, Hu, Yichun, Hogan, Susan L., Mercke, Nickie, Gomez, Madeleine, O’Bryant, Cindy L., Bowles, Daniel W., George, Blessy, Wen, Xia, Buckley, Brian, Aleksunes, Lauren, Joy

Journal:

European Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 517 KB

english, 2018

7

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase

Szilagyi, John T., Fussell, Karma C., Wang, Yun, Jan, Yi-Hua, Mishin, Vladimir, Richardson, Jason R., Heck, Diane E., Yang, Shaojun, Aleksunes, Lauren M., Laskin, Debra L., Laskin, Jeffrey D.

Journal:

Toxicology and Applied Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

8

Transcription factor-mediated regulation of the BCRP/ ABCG2 efflux transporter: a review across tissues and species

Gorczyca, Ludwik, Aleksunes, Lauren M.

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2020

Language:

english

File:

PDF, 1.22 MB

english, 2020

9

Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling

Zhao, Linlin, Ciallella, Heather L., Aleksunes, Lauren M., Zhu, Hao

Journal:

Drug Discovery Today

Year:

2020

File:

PDF, 2.34 MB

2020

10

Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor-E2–related factor-2 transcriptional pathway

Jonathan M. Maher, Matthew Z. Dieter, Lauren M. Aleksunes, Angela L. Slitt, Grace Guo, Yuji Tanaka, George L. Scheffer, Jefferson Y. Chan, Jose E. Manautou, Ying Chen, Timothy P. Dalton, Masayuki Yama

Journal:

Year:

2007

Language:

english

File:

PDF, 1.13 MB

english, 2007

11

Gender divergent expression of Nqo1 in Sprague Dawley and August Copenhagen x Irish rats

Lisa M. Augustine, Craig D. Fisher, Andrew J Lickteig, Lauren M. Aleksunes, Angela L. Slitt, Nathan J. Cherrington

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2008

Language:

english

File:

PDF, 249 KB

english, 2008

12

Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1

Qiuqiong Cheng, Keiko Taguchi, Lauren M. Aleksunes, José E. Manautou, Nathan J. Cherrington, Masayuki Yamamoto, Angela L. Slitt

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2011

Language:

english

File:

PDF, 258 KB

english, 2011

13

Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen

Jeffrey S. Moffit, Lauren M. Aleksunes, Michael J. Kardas, Angela L. Slitt, Curtis D. Klaassen, José E. Manautou

Journal:

Year:

2007

Language:

english

File:

PDF, 497 KB

english, 2007

14

Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment

Lauren M. Aleksunes, Lisa M. Augustine, George L. Scheffer, Nathan J. Cherrington, José E. Manautou

Journal:

Year:

2008

Language:

english

File:

PDF, 855 KB

english, 2008

15

Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes

Scott A. Reisman, Lauren M. Aleksunes, Curtis D. Klaassen

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 746 KB

english, 2009

16

Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2

Lauren M. Aleksunes, Angela L. Slitt, Jonathan M. Maher, Lisa M. Augustine, Michael J. Goedken, Jefferson Y. Chan, Nathan J. Cherrington, Curtis D. Klaassen, José E. Manautou

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.24 MB

english, 2008

17

Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity

Yuji Tanaka, Lauren M. Aleksunes, Michael J. Goedken, Chuan Chen, Scott A. Reisman, José E. Manautou, Curtis D. Klaassen

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.89 MB

english, 2008

18

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity

Bo Kong, Iván L. Csanaky, Lauren M. Aleksunes, Meghan Patni, Qi Chen, Xiaochao Ma, Hartmut Jaeschke, Scott Weir, Melinda Broward, Curtis D. Klaassen, Grace L. Guo

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

19

The traditional ayurvedic medicine, Eugenia jambolana (Jamun fruit), decreases liver inflammation, injury and fibrosis during cholestasis

Ajay C. Donepudi, Lauren M. Aleksunes, Maureen V. Driscoll, Navindra P. Seeram, Angela L. Slitt

Journal:

Liver International

Year:

2012

Language:

english

File:

PDF, 882 KB

english, 2012

20

Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPAR -, and Nrf2-Null Mice

Aleksunes, L. M., Klaassen, C. D.

Journal:

Drug Metabolism and Disposition

Year:

2012

Language:

english

File:

PDF, 6.15 MB

english, 2012

21

Endocrine and metabolic regulation of renal drug transporters

Lindsay L. Yacovino, Lauren M. Aleksunes

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2012

Language:

english

File:

PDF, 186 KB

english, 2012

22

Regulation of transporter expression in mouse liver, kidney, and intestine during extrahepatic cholestasis

Angela L. Slitt, Katryn Allen, Jennifer Morrone, Lauren M. Aleksunes, Chuan Chen, Jonathan M. Maher, José E. Manautou, Nathan J. Cherrington, Curtis D. Klaassen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 805 KB

english, 2007

23

Renal efflux transporter expression in pregnant mice with Type I diabetes

Lindsay L. Yacovino, Lauren M. Aleksunes

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

24

Inflammatory Regulation of ATP Binding Cassette Efflux Transporter Expression and Function in Microglia

Gibson, C. J., Hossain, M. M., Richardson, J. R., Aleksunes, L. M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 3.99 MB

english, 2012

25

Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice

Lisa D. Beilke, Lauren M. Aleksunes, Erik R. Olson, David G. Besselsen, Curtis D. Klaassen, Katerina Dvorak, Nathan J. Cherrington

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

26

IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

Ahmed, M.S., Aleksunes, L.M., Boeuf, P., Chung, M.K., Daoud, G., Desoye, G., Díaz, P., Golos, T.G., Illsley, N.P., Kikuchi, K., Komatsu, R., Lao, T., Morales-Prieto, D.M., Nanovskaya, T., Nobuzane, T.

Journal:

Year:

2013

Language:

english

File:

PDF, 172 KB

english, 2013

27

Drug-Metabolizing Enzyme and Transporter Expression in a Mouse Model of Diabetes and Obesity

Cheng, Qiuqiong, Aleksunes, Lauren M., Manautou, José E., Cherrington, Nathan J., Scheffer, George L., Yamasaki, Hideki, Slitt, Angela L.

Journal:

Molecular Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 2.53 MB

english, 2008

28

Severe diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice

Vijay R More, Xia Wen, Paul E Thomas, Lauren M Aleksunes…

Journal:

Comparative Hepatology

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

29

Pregnancy Represses Induction of Efflux Transporters in Livers of Type I Diabetic Mice

Lauren M. Aleksunes, Jialin Xu, Eugenia Lin, Xia Wen…

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 725 KB

english, 2013

30

Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection)

O'Connor, Meeghan A., Koza-Taylor, Petra, Campion, Sarah N., Aleksunes, Lauren M., Gu, Xinsheng, Enayetallah, Ahmed E., Lawton, Michael P., Manautou, José E.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

31

Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver

Zhu, Yan, Li, Guodong, Dong, Yafeng, Zhou, Helen H., Kong, Bo, Aleksunes, Lauren M., Richardson, Jason R., Li, Fei, Guo, Grace L.

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

32

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice

Wen, Xia, Buckley, Brian, McCandlish, Elizabeth, Goedken, Michael J., Syed, Samira, Pelis, Ryan, Manautou, José E., Aleksunes, Lauren M.

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

33

Hepatic and renal Bcrp transporter expression in mice treated with perfluorooctanoic acid

Eldasher, Lobna M., Wen, Xia, Little, Michael S., Bircsak, Kristin M., Yacovino, Lindsay L., Aleksunes, Lauren M.

Journal:

Year:

2013

Language:

english

File:

PDF, 797 KB

english, 2013

34

Regional expression of the BCRP/ABCG2 transporter in term human placentas

Memon, Naureen, Bircsak, Kristin M., Archer, Faith, Gibson, Christopher J., Ohman-Strickland, Pamela, Weinberger, Barry I., Parast, Mana M., Vetrano, Anna M., Aleksunes, Lauren M.

Journal:

Reproductive Toxicology

Year:

2014

Language:

english

File:

PDF, 1.88 MB

english, 2014

35

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice

Rudraiah, Swetha, Moscovitz, Jamie E., Donepudi, Ajay C., Campion, Sarah N., Slitt, Angela L., Aleksunes, Lauren M., Manautou, José E.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.90 MB

english, 2014

36

Fibroblast growth factor 15 deficiency impairs liver regeneration in mice

Kong, B., Huang, J., Zhu, Y., Li, G., Williams, J., Shen, S., Aleksunes, L. M., Richardson, J. R., Apte, U., Rudnick, D. A., Guo, G. L.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2014

Language:

english

File:

PDF, 3.82 MB

english, 2014

37

Inhibition of Human MDR1 and BCRP Transporter ATPase Activity by Organochlorine and Pyrethroid Insecticides

Bircsak, Kristin M., Richardson, Jason R., Aleksunes, Lauren M.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2013

Language:

english

File:

PDF, 320 KB

english, 2013

38

Effects of Developmental Deltamethrin Exposure on White Adipose Tissue Gene Expression

Armstrong, Laura E., Driscoll, Maureen V., More, Vijay R., Donepudi, Ajay C., Xu, Jialin, Baker, Angela, Aleksunes, Lauren M., Richardson, Jason R., Slitt, Angela L.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2013

Language:

english

File:

PDF, 122 KB

english, 2013

39

Effects of Developmental Deltamethrin Exposure on White Adipose Tissue Gene Expression

Armstrong, Laura E., Driscoll, Maureen V., More, Vijay R., Donepudi, Ajay C., Xu, Jialin, Baker, Angela, Aleksunes, Lauren M., Richardson, Jason R., Slitt, Angela L.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2013

Language:

english

File:

PDF, 202 KB

english, 2013

40

Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease

Lickteig, A. J., Fisher, C. D., Augustine, L. M., Aleksunes, L. M., Besselsen, D. G., Slitt, A. L., Manautou, J. E., Cherrington, N. J.

Journal:

Drug Metabolism and Disposition

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

41

MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells

Wen, X., Gibson, C. J., Yang, I., Buckley, B., Goedken, M. J., Richardson, J. R., Aleksunes, L. M.

Journal:

Toxicological Sciences

Year:

2014

Language:

english

File:

PDF, 5.42 MB

english, 2014

42

241: Modulation of hormone secretion by the environmental chemical zearalenone in trophoblasts differentiated from human embryonic stem cells

Gupta, Vivek, Bircsak, Kristin, Lu, Chi-Wei, Aleksunes, Lauren

Journal:

American Journal of Obstetrics and Gynecology

Year:

2015

Language:

english

File:

PDF, 51 KB

english, 2015

43

506: Impairment of the placental barrier in response to activation of HIF-1α hypoxia-related signaling

Francois, Lissa, Bircsak, Kristin, Aleksunes, Lauren

Journal:

American Journal of Obstetrics and Gynecology

Year:

2015

Language:

english

File:

PDF, 165 KB

english, 2015

44

Activation of NRF2 Signaling in HEK293 Cells by a First-in-Class Direct KEAP1-NRF2 Inhibitor

Wen, Xia, Thorne, Gabriell, Hu, Longqin, Joy, Melanie S., Aleksunes, Lauren M.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2015

Language:

english

File:

PDF, 559 KB

english, 2015

45

Correlation between Genotype and Phenotypic Categorization of Staphylococci Based on Methicillin Susceptibility and Resistance

Gradelski, E., Valera, L., Aleksunes, L., Bonner, D., Fung-Tomc, J.

Journal:

Journal of Clinical Microbiology

Year:

2001

Language:

english

File:

PDF, 51 KB

english, 2001

46

Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain

Fortin, M. C., Aleksunes, L. M., Richardson, J. R.

Journal:

Drug Metabolism and Disposition

Year:

2013

Language:

english

File:

PDF, 859 KB

english, 2013

47

Transcription Factor-Mediated Regulation of Carboxylesterase Enzymes in Livers of Mice

Zhang, Y., Cheng, X., Aleksunes, L., Klaassen, C. D.

Journal:

Drug Metabolism and Disposition

Year:

2012

Language:

english

File:

PDF, 2.60 MB

english, 2012

48

Transcriptional Regulation of Renal Cytoprotective Genes by Nrf2 and Its Potential Use as a Therapeutic Target to Mitigate Cisplatin-Induced Nephrotoxicity

Aleksunes, L. M., Goedken, M. J., Rockwell, C. E., Thomale, J., Manautou, J. E., Klaassen, C. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2010

Language:

english

File:

PDF, 3.74 MB

english, 2010

49

Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases

Barnes, S. N., Aleksunes, L. M., Augustine, L., Scheffer, G. L., Goedken, M. J., Jakowski, A. B., Pruimboom-Brees, I. M., Cherrington, N. J., Manautou, J. E.

Journal:

Drug Metabolism and Disposition

Year:

2007

Language:

english

File:

PDF, 418 KB

english, 2007

50

Nuclear Factor Erythroid 2-Related Factor 2 Deletion Impairs Glucose Tolerance and Exacerbates Hyperglycemia in Type 1 Diabetic Mice

Aleksunes, L. M., Reisman, S. A., Yeager, R. L., Goedken, M. J., Klaassen, C. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2010

Language:

english

File:

PDF, 3.18 MB

english, 2010