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51

Skin Ferrochelatase Levels and Photosensitivity

Leboulche, Philippe, Mathews-Roth, Micheline

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 51 KB

english, 2005

52

Distribution of Lentiviral Vector Integration Sites in Mice Following Therapeutic Gene Transfer to Treat β-thalassemia

Ronen, Keshet, Negre, Olivier, Roth, Shannah, Colomb, Charlotte, Malani, Nirav, Denaro, Maria, Brady, Troy, Fusil, Floriane, Gillet-Legrand, Beatrix, Hehir, Kathleen, Beuzard, Yves, Leboulch, Philippe

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 611 KB

english, 2011

53

Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: Analysis of the ability to support expansion of cord blood hematopoietic progenitor cells

Nishioka, Keisuke, Fujimori, Yoshihiro, Hashimoto-Tamaoki, Tomoko, Kai, Shunro, Qiu, Huiying, Kobayashi, Naoya, Tanaka, Noriaki, Westerman, Karen, Leboulch, Philippe, Hara, Hiroshi

Journal:

International Journal of Oncology

Year:

2003

Language:

english

File:

PDF, 2.47 MB

english, 2003

54

Retroviral Transfer of a Human β-Globin/δ-Globin Hybrid Gene Linked to β Locus Control Region Hypersensitive Site 2 Aimed at the Gene Therapy of Sickle Cell Disease

Ken J. Takekoshi, Young H. Oh, Karen W. Westerman, Irving M. London and Philippe Leboulch

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.19 MB

english, 1995

55

Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis

Goupille, Olivier, Penglong, Tipparat, Kadri, Zahra, Granger-Locatelli, Marine, Fucharoen, Suthat, Maouche-Chrétien, Leila, Prost, Stéphane, Leboulch, Philippe, Chrétien, Stany

Journal:

Biochemical and Biophysical Research Communications

Year:

2016

Language:

english

File:

PDF, 2.37 MB

english, 2016

56

REVERSIBLY IMMORTALIZED HUMAN ENDOTHELIAL SCAVENGER CELLS TO DEVELOP A BIOARTIFICIAL ORGAN

Noguchi, H., Kobayashi, N., Totsugawa, T., Watanabe, T., Matsumura, T., Fujiwara, T., Tanaka, N., Westerman, K. A., Leboulch, P.

Journal:

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

57

ENHANCED LIVER-SPECIFIC FUNCTIONS BY COCULTIVATION OF IMMORTALIZED HUMAN HEPATOCYTES AND LIVER FAT-STORING CELLS

Watanabe, T., Kobayashi, N., Noguchi, H., Totsugawa, T., Matsumura, T., Fujiwara, T., Tanaka, N., Hikida, M., Ohmori, A., Westerman, K. A., Leboulch, P.

Journal:

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

58

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β A(T87Q) - Globin Gene

Negre, Olivier, Eggimann, Anne-Virginie, Beuzard, Yves, Ribeil, Jean-Antoine, Bourget, Philippe, Borwornpinyo, Suparerk, Hongeng, Suradej, Hacein-Bey, Salima, Cavazzana, Marina, Leboulch, Philippe, Pa

Journal:

Human Gene Therapy

Year:

2016

Language:

english

File:

PDF, 630 KB

english, 2016

59

EXPANSION OF PRIMARY HUMAN HEPATOCYTE POPULATIONS BY RETROVIRAL GENE TRANSFER AND ADENOVIRUS-MEDIATED CRELOXP SITE-SPECIFIC RECOMBINATION

Kobayashi, N., Noguchi, H., Fujiwara, T., Tanaka, N., Westerman, K. A., Leboulch, P.

Journal:

Year:

2000

Language:

english

File:

PDF, 1.28 MB

english, 2000

60

hTERT-TRANSDUCED HUMAN HEPATOCYTES AS A SOURCE OF A BIOARTIFICIAL LIVER

Totsugawa, T., Kobayashi, N., Noguchi, H., Watanabe, T., Matsumura, T., Fujiwara, T., Tanaka, N., Hikida, M., Ohmori, A., Westerman, K. A., Leboulch, P.

Journal:

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

61

TIGHTLY REGULATED HUMAN HEPATOCYTES AS A SOURCE OF A BIOARTIFICIAL LIVER

Kobayashi, N., Noguchi, H., Totsugawa, T., Watanabe, T., Matsumura, T., Fujiwara, T., Tanaka, N., Westerman, K. A., Leboulch, P.

Journal:

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

62

CONSTRUCTION OF AN IMMORTALIZED LIVER SINUSOIDAL ENDOTHELIAL CELL LINE FOR LIVER-TARGETED TISSUE ENGINEERING

Matsumura, T., Kobayashi, N., Noguchi, H., Totsugawa, T., Watanabe, T., Fujiwara, T., Tanaka, N., Hikida, M., Ohmori, A., Westerman, K. A., Leboulch, P.

Journal:

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

63

ESTABLISHMENT OF AN IMMORTALIZED HUMAN PANCREATIC BETA CELL LINE

Narushima, M, Kobayashi, N, Westerman, K A, Fukazawa, T, Sakaguchi, M, Tanaka, Y, Lakey, Jonathan RT., Leboulch, Philippe, Tanaka, N

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 327 KB

english, 2004

64

Outcomes of Gene Therapy for Severe Sickle Cell Disease (SCD) via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral ßAT87Q-Globin Vector

Soni, Sandeep, Tisdale, John F., Hsieh, Matthew, Kanter, Julie, Leboulch, Philippe, Cavazzana, Marina

Journal:

Biology of Blood and Marrow Transplantation

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

65

IMPROVEMENT IN DIFFERENTIATED HEPATIC PHENOTYPE OF IMMORTALIZED HEPATOCYTES BY ADENOVIRUS-MEDIATED P21 GENE TRANSFER

Kobayashi, N., Noguchi, H., Totsugawa, T., Watanabe, T., Matsumura, T., Fujiwara, T., Tanaka, N., Westerman, K. A., Leboulch, P.

Journal:

Year:

2001

Language:

english

File:

PDF, 2.18 MB

english, 2001

66

Expansion of Human Hepatocyte Populations by a Retroviral Gene Transfer of Simian Virus 40 Large T Antigen

Kobayashi, Naoya, Westerman, Karen A., Taguchi, Takehito, Sakaguchi, Masakiyo, Fujiwara, Toshiyoshi, Urata, Haruo, Kishimoto, Noboru, Hayashi, Nobuyuki, Nakaji, Shuhei, Murakami, Takuro, Leboulch, Phi

Journal:

Year:

2001

Language:

english

File:

PDF, 368 KB

english, 2001

67

TREATMENT OF ACUTE LIVER FAILURE WITH TRANSPLANTATION OF REVERSIBLY IMMORTALIZED HUMAN HEPATOCYTES.

Kobayashi, N., Noguchi, H., Westerman, Karen A., Fujiwara, T., Tanaka, N., Leboulch, Phillipe

Journal:

Transplantation Journal

Year:

2000

File:

PDF, 908 KB

2000

68

Tolerance by Selective In Vivo Expansion of Foreign Major Histocompatibility Complex-Transduced Autologous Bone Marrow1

Zhang, Jia Lin, Cai, Jin, Walls, Shannon, Jackson, John D., Kuszynski, Charles A., Zhao, Yong, Pawliuk, Robert, Leboulch, Philippe, Fox, Ira J.

Journal:

Transplantation Journal

Year:

2005

Language:

english

File:

PDF, 864 KB

english, 2005

69

Construction of a Differentiated Human Hepatocyte Cell Line Expressing the Herpes Simplex Virus-Thymidine Kinase Gene

Kobayashi, Naoya, Miyazaki, Masahiro, Westerman, Karen A., Noguchi, Hirofumi, Sakaguchi, Masakiyo, Totsugawa, Toshinori, Watanabe, Takamasa, Matsumura, Toshihisa, Fujiwara, Toshiyoshi, Leboulch, Phili

Journal:

Year:

2001

Language:

english

File:

PDF, 1.04 MB

english, 2001

70

134 HIV DNA Integration

Bushman, Frederic D., Brady, Troy, Malani, Nirav, Leboulch, Philippe, Hacein-Bey, Salima, Cavazzana-Calvo, Marina, Ocwieja, Karen, Roth, Shoshannah, Berry, Charles C.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

71

Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT

Maruyama, Masanobu, Kobayashi, Naoya, Westerman, Karen A., Sakaguchi, Masakiyo, Allain, Jean E., Totsugawa, Toshinori, Okitsu, Teru, Fukazawa, Takuya, Weber, Anne, Stolz, Donna B., Leboulch, Philippe,

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 925 KB

english, 2004

72

High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing

Ling, Chen, Bhukhai, Kanit, Yin, Zifei, Tan, Mengqun, Yoder, Mervin C., Leboulch, Philippe, Payen, Emmanuel, Srivastava, Arun

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

73

Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies

Mouka, Aurélie, Izard, Vincent, Tachdjian, Gérard, Brisset, Sophie, Yates, Frank, Mayeur, Anne, Drévillon, Loïc, Jarray, Rafika, Leboulch, Philippe, Maouche-Chrétien, Leila, Tosca, Lucie

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

74

Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure.

Leboulch, P, Huang, G M, Humphries, R K, Oh, Y H, Eaves, C J, Tuan, D Y, London, I M

Journal:

The EMBO Journal

Year:

1994

Language:

english

File:

PDF, 2.60 MB

english, 1994

75

10. High-Efficiency Transduction of Primary Human CD34+ Hematopoietic Stem/Progenitor Cells by AAV6 Serotype Vectors: Strategies for Overcoming Donor Variation and Implications in Genome Editing

Yin, Zifei, Bukhai, Kanit, Aslanidi, George, Ling, Chen, Tan, Mengqun, Yoder, Mervin, Leboulch, Philippe, Payen, Emmanuel, Srivastava, Arun

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

76

LentiGlobin gene therapy for transfusion-dependent β-Thalassemia: Update from the northstar HGB-204 phase 1/2 clinical study

Rasko, J., Thompson, A., Kwiatkowski, J., Hongeng, S., Schiller, G.J., Anurathapan, U., Cavazzana-Calvo, M., Ho, P., von Kalle, C., Kletzel, M., Leboulch, P., Vichinsky, E., Petrusich, A., Asmal, M.,

Journal:

Year:

2017

Language:

english

File:

PDF, 79 KB

english, 2017

77

Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

Rosenwald, Igor B., Kaspar, Roger, Rousseau, Dennis, Gehrke, Lee, Leboulch, Philippe, Chen, Jane-Jane, Schmidt, Emmett V., Sonenberg, Nahum, London, Irving M.

Journal:

Journal of Biological Chemistry

Year:

1995

Language:

english

File:

PDF, 127 KB

english, 1995

78

Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination.

Westerman, K. A., Leboulch, P.

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.60 MB

english, 1996

79

Clinical outcomes of lentiviral gene therapy for the beta-hemogolobinpathies

Leboulch, Philippe

Journal:

Experimental Hematology

Year:

2017

Language:

english

File:

PDF, 119 KB

english, 2017

80

The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis

Goupille, Olivier, Penglong, Tipparat, Kadri, Zahra, Granger-Locatelli, Marine, Denis, Raphaël, Luquet, Serge, Badoual, Cécile, Fucharoen, Suthat, Maouche-Chrétien, Leila, Leboulch, Philippe, Chrétien

Journal:

Year:

2017

Language:

english

File:

PDF, 3.93 MB

english, 2017

81

Efficient Cre/loxP Site-Specific Recombination in a HepG2 Human Liver Cell Line

Kobayashi, Naoya, Noguchi, Hirofumi, Westerman, Karen A., Matsumura, Toshihisa, Watanabe, Takamasa, Totsugawa, Toshinori, Fujiwara, Toshiyoshi, Leboulch, Philippe, Tanaka, Noriaki

Journal:

Cell Transplantation

Year:

2000

Language:

english

File:

PDF, 3.10 MB

english, 2000

82

Safety Following Autologous Transplantation with Lentiglobin Gene Therapy for Transfusion-Dependent β-Thalassemia (TDT) in the Northstar Hgb-204 Study

Walters, Mark C., Kwiatkowski, Janet L., Rasko, John E.J., Hongeng, Suradej, Schiller, Gary J., Anurathapan, Usanarat, Cavazzana, Marina, Ho, Phoebe Joy, von Kalle, Christof, Kletzel, Morris, Leboulch

Journal:

Biology of Blood and Marrow Transplantation

Year:

2018

Language:

english

File:

PDF, 85 KB

english, 2018

83

UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells

Ngom, Mor, Imren, Suzan, Maetzig, Tobias, Adair, Jennifer E., Knapp, David J.H.F., Chagraoui, Jalila, Fares, Iman, Bordeleau, Marie-Eve, Sauvageau, Guy, Leboulch, Philippe, Eaves, Connie, Humphries, R

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

84

Cre/loxP-Based Reversible Immortalization of Human Hepatocytes

Kobayashi, Naoya, Noguchi, Hirofumi, Westerman, Karen A., Watanabe, Takamasa, Matsumura, Toshihisa, Totsugawa, Toshinori, Fujiwara, Toshiyoshi, Leboulch, Philippe, Tanaka, Noriaki

Journal:

Cell Transplantation

Year:

2001

File:

PDF, 123 KB

2001

85

Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure.

Leboulch, P., Huang, G.M., Humphries, R.K., Oh, Y.H., Eaves, C.J., Tuan, D.Y., London, I.M.

Journal:

The EMBO Journal

Year:

1994

Language:

english

File:

PDF, 2.61 MB

english, 1994

86

Enhanced transduction of Macaca fascicularis hematopoietic cells with chimeric lentiviral vectors

Sii-Felice, Karine, Castillo Padilla, Javier, Relouzat, Francis, Cheuzeville, Joëlle, Tantawet, Siriporn, Maouche-Chretien, Leila, Le Grand, Roger, Leboulch, Philippe, Payen, Emmanuel

Journal:

Human Gene Therapy

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

87

The integrity of the FOG‐2 LXCXE pRb‐binding motif is required for small intestine homeostasis

Goupille, Olivier, Kadri, Zahra, Langelé, Amandine, Luccantoni, Sophie, Badoual, Cécile, Leboulch, Philippe, Chrétien, Stany

Journal:

Experimental Physiology

Year:

2019

Language:

english

File:

PDF, 2.51 MB

english, 2019

88

CLINICAL OUTCOMES OF LENTIGLOBIN GENE THERAPY FOR TRANSFUSION-DEPENDENT β-THALASSAEMIA (TDT) FOLLOWING COMPLETION OF THE NORTHSTAR (HGB-204) STUDY

Walters, M. C., Kwiatkowski, J. L., Rasko, J. E.J., Hongeng, S., Schiller, G. J., Anurathapan, U., Cavazzana, M., Ho, P. J., Schmidt, M., Kletzel, M., Leboulch, P., Vichinsky, E., Deary, B., Chen, Y.,

Journal:

Year:

2019

File:

PDF, 334 KB

2019

89

2D simulation of hydride blister cracking during a RIA transient with the fuel code ALCYONE

Sercombe, JÃ©rÃ´me, Helfer, Thomas, Federici, Eric, Leboulch, David, Le Jolu, Thomas, Hellouin de MÃ©nibus, Arthur, Bernaudat, Christian

Journal:

EPJ Nuclear Sciences & Technologies

Year:

2016

File:

PDF, 4.72 MB

2016

90

Transcriptional Behavior of LCR Enhancer Elements Integrated at the Same Chromosomal Locus by Recombinase-Mediated Cassette Exchange

Bouhassira, Eric E., Westerman, Karen, Leboulch, Philippe

Journal:

Year:

1997

File:

PDF, 1.02 MB

1997

91

Long-Term Transfer and Expression of the Human Î²-Globin Gene in a Mouse Transplant Model

Raftopoulos, Harry, Ward, Maureen, Leboulch, Philippe, Bank, Arthur

Journal:

Year:

1997

File:

PDF, 393 KB

1997

92

Locus control region activity by 5â²HS3 requires a functional interaction with Î²-globin gene regulatory elements: expression of novel Î²/Î³-globin hybrid transgenes

Rubin, Joel E., Pasceri, Peter, Wu, Xiumei, Leboulch, Philippe, Ellis, James

Journal:

Year:

2000

File:

PDF, 279 KB

2000

93

Gene Therapy of the Î² Hemoglobinopathies: Success and Challenges

Payen, Emmanuel, Leboulch, Philippe

Journal:

Year:

2019

File:

PDF, 490 KB

2019