Largent-Milnes,: search on Z-Library

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1

Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents

Doyle, Timothy M., Janes, Kali, Chen, Zhoumou, Grace, Peter M., Esposito, Emanuela, Cuzzocrea, Salvatore, Largent-Milnes, Tally M., Neumann, William L., Watkins, Linda R., Spiegel, Sarah, Vanderah, To

Journal:

Year:

2020

File:

PDF, 1.24 MB

2020

2

Distinguishing and phenotype monitoring of traumatic brain injury and post-concussion syndrome including chronic migraine in serum of Iraq and Afghanistan war veterans

Hanas, Jay S., Hocker, James R. S., Lerner, Megan R., Couch, James R., Largent-Milnes, Tally

Journal:

Year:

2019

Language:

english

File:

PDF, 2.67 MB

english, 2019

3

Cannabinoid receptor 2: an innovative multi-targeted approach in the treatment of breast cancer and related skeletal metastasis

K. Hanlon, A. Ondoua, T. Largent-Milnes, A. Symons, P. Mantyh, T. Vanderah

Journal:

The Journal of Pain

Year:

2012

Language:

english

File:

PDF, 36 KB

english, 2012

4

Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Chen, Zhoumou, Doyle, Timothy M., Luongo, Livio, Largent-Milnes, Tally M., Giancotti, Luigino Antonio, Kolar, Grant, Squillace, Silvia, Boccella, Serena, Walker, John K., Pendleton, Alexander, Spiegel

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

5

Cannabinoid-2 Agonism with AM2301 Mitigates Morphine-Induced Respiratory Depression

Wiese, Beth M., Liktor-Busa, Erika, Levine, Aidan, Couture, Sarah A., Nikas, Spyros P., Ji, Lipin, Liu, Yingpeng, Mackie, Kenneth, Makriyannis, Alexandros, Largent-Milnes, Tally M., Vanderah, Todd W.

Journal:

Cannabis and Cannabinoid Research

Year:

2020

File:

PDF, 1.26 MB

2020

6

Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain

Katherine E. Hanlon, Dave S. Herman, Richard S. Agnes, Tally M. Largent-Milnes, Isuru R. Kumarasinghe, Sho W. Ma, Wenhong Guo, Yeon-Sun Lee, Michael H. Ossipov, Victor J. Hruby, Josephine Lai, Frank P

Journal:

Year:

2011

Language:

english

File:

PDF, 710 KB

english, 2011

7

Structure–Activity Relationships of [des-Arg 7 ]Dynorphin A Analogues at the κ Opioid Receptor

Ramos-Colon, Cyf N., Lee, Yeon Sun, Remesic, Michael, Hall, Sara M., LaVigne, Justin, Davis, Peg, Sandweiss, Alexander J., McIntosh, Mary I., Hanson, Jessica, Largent-Milnes, Tally M., Vanderah, Todd

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 624 KB

english, 2016

8

Editorial: Novel Molecular Targets for the Treatment of Pain

Largent-Milnes, Tally M., Canals, Meritxell, Streicher, John M.

Journal:

Frontiers in Molecular Neuroscience

Year:

2020

File:

PDF, 121 KB

2020

9

Building a Better Analgesic: Multifunctional Compounds that Address Injury-Induced Pathology to Enhance Analgesic Efficacy while Eliminating Unwanted Side Effects

Largent-Milnes, T. M., Brookshire, S. W., Skinner, D. P., Hanlon, K. E., Giuvelis, D., Yamamoto, T., Davis, P., Campos, C. R., Nair, P., Deekonda, S., Bilsky, E. J., Porreca, F., Hruby, V. J., Vandera

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2013

Language:

english

File:

PDF, 749 KB

english, 2013

10

Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain

Giri, Aswini Kumar, Apostol, Christopher R., Wang, Yue, Forte, Brittany L., Largent-Milnes, Tally M., Davis, Peg, Rankin, David, Molnar, Gabriella, Olson, Keith M., Porreca, Frank, Vanderah, Todd W.,

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 774 KB

english, 2015

11

Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations

Deekonda, Srinivas, Cole, Jacob, Sunna, Sydney, Rankin, David, Largent-Milnes, Tally M., Davis, Peg, BassiriRad, Neemah M., Lai, Josephine, Vanderah, Todd W., Porecca, Frank, Hruby, Victor J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 741 KB

english, 2016

12

An underrepresented majority: A systematic review utilizing allodynic criteria to examine the present scarcity of discrete animal models for episodic migraine

Levine, Aidan, Vanderah, Todd W, Largent-Milnes, Tally M

Journal:

Year:

2020

File:

PDF, 577 KB

2020

13

CB2 receptor agonists act as a disease-modifying treatment by attenuating breast cancer-induced bone pain and improving bone health in a murine model of breast cancer metastases

A. Ondoua, K. Hanlon, T. Largent-Milnes, D. Sukhtankar, T. King, P. Mantyh, T. Vanderah

Journal:

The Journal of Pain

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

14

Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential

Sandweiss, A J, McIntosh, M I, Moutal, A, Davidson-Knapp, R, Hu, J, Giri, A K, Yamamoto, T, Hruby, V J, Khanna, R, Largent-Milnes, T M, Vanderah, T W

Journal:

Molecular Psychiatry

Year:

2017

Language:

english

File:

PDF, 1.83 MB

english, 2017

15

Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain

Moutal, Aubin, Luo, Shizhen, Largent-Milnes, Tally M., Vanderah, Todd W., Khanna, Rajesh

Journal:

Neurobiology of Pain

Year:

2018

Language:

english

File:

PDF, 757 KB

english, 2018

16

Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA

S Tumati, WR Roeske, T Largent-Milnes, R Wang, TW Vanderah, EV Varga

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

17

Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons

Largent-Milnes, T. M., Hegarty, D. M., Aicher, S. A., Andresen, M. C.

Journal:

Journal of Neurophysiology

Year:

2014

Language:

english

File:

PDF, 2.89 MB

english, 2014

18

Synthesis and StructureâActivity Relationships of 5â²-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.

Vekariya, Rakesh H., Lei, Wei, Ray, Abhisek, Sainai, Surendra K., Zhang, Sixue, Molnar, Gabriella, Barlow, Deborah, Karlage, Kelly L., Bilsky, Edward, Houseknecht, Karen, Largent-Milnes, Tally M., Str

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.16 MB

2020

19

Acute visceral pain relief mediated by A3AR agonists in rats

Lucarini, Elena, Coppi, Elisabetta, Micheli, Laura, Parisio, Carmen, Vona, Alessia, Cherchi, Federica, Pugliese, Anna M., Pedata, Felicita, Failli, Paola, Palomino, Seph, Wahl, Jared, Largent-Milnes,

Journal:

Year:

2020

File:

PDF, 932 KB

2020

20

Tachykinin NK1 receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation

Suneeta Tumati, Tally M. Largent-Milnes, Attila I. Keresztes, Takashi Yamamoto, Todd W. Vanderah, William R. Roeske, Victor J. Hruby, Eva V. Varga

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 925 KB

english, 2012

21

Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist

Suneeta Tumati, Tally M. Largent-Milnes, Attila Keresztes, Jiyang Ren, William R. Roeske, Todd W. Vanderah, Eva V. Varga

Journal:

Journal of Neuroimmunology

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

22

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

Liktor-Busa, Erika, Blawn, Kiera T., Kellohen, Kathryn L., Wiese, Beth M., Verkhovsky, Vani, Wahl, Jared, Vivek, Anjali, Palomino, Seph M., Davis, Thomas P., Vanderah, Todd W., Largent-Milnes, Tally M

Journal:

Year:

2020

File:

PDF, 2.53 MB

2020

23

Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists

Lozano-Ondoua, Alysia N, Hanlon, Katherine E, Symons-Liguori, Ashley M, Largent-Milnes, Tally M, Havelin, Josh J, Ferland, Henry L, Chandramouli, Anupama, Owusu-Ankomah, Mabel, Nikolich-Zugich, Tijana

Journal:

Journal of Bone and Mineral Research

Year:

2013

Language:

english

File:

PDF, 2.60 MB

english, 2013

24

Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists

Grenald, Shaness A., Young, Madison A., Wang, Yue, Ossipov, Michael H., Ibrahim, Mohab M., Largent-Milnes, Tally M., Vanderah, Todd W.

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 2.19 MB

english, 2017

25

Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation

Grenald, Shaness A., Doyle, Timothy M., Zhang, Hong, Slosky, Lauren M., Chen, Zhoumou, Largent-Milnes, Tally M., Spiegel, Sarah, Vanderah, Todd W., Salvemini, Daniela

Journal:

Year:

2017

Language:

english

File:

PDF, 1.44 MB

english, 2017

26

Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain

Forte, Brittany L., Slosky, Lauren M., Zhang, Hong, Arnold, Moriah R., Staatz, William D., Hay, Meredith, Largent-Milnes, Tally M., Vanderah, Todd W.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

27

A peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain

Zhang, Hong, Lund, Dominique M., Ciccone, Haley A., Staatz, William D., Ibrahim, Mohab M., Largent-Milnes, Tally M., Seltzman, Herbert H., Spigelman, Igor, Vanderah, Todd W.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.55 MB

english, 2018

28

Continuous Remote Ischemic Conditioning Attenuates Cognitive and Motor Deficits From Moderate Traumatic Brain Injury

Pandit, Viraj, Khan, Muhammad, Zakaria, El Rasheid, Largent-Milnes, Tally M., Hamidi, Mohammad, O’Keeffe, Terence, Vanderah, Todd W., Joseph, Bellal

Journal:

Journal of Trauma and Acute Care Surgery

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

29

Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models

Stine, Carrie, Coleman, Deziree L., Flohrschutz, Austin T., Thompson, Austen L., Mishra, Sanket, Blagg, Brian S., Largent-Milnes, Tally M., Lei, Wei, Streicher, John M.

Journal:

Year:

2020

File:

PDF, 1.25 MB

2020

30

Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance

TM Largent-Milnes, T Yamamoto, P Nair, JW Moulton, VJ Hruby, J Lai, F Porreca, TW Vanderah

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.35 MB

english, 2010

31

Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands

Deekonda, Srinivas, Wugalter, Lauren, Kulkarni, Vinod, Rankin, David, Largent-Milnes, Tally M., Davis, Peg, Bassirirad, Neemah M., Lai, Josephine, Vanderah, Todd W., Porreca, Frank, Hruby, Victor J.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 694 KB

english, 2015

32

Remote Ischemic Conditioning Preserves Cognition and Motor Coordination in a Mouse Model of Traumatic Brain Injury

Sandweiss, Alexander J., Azim, Asad, Ibraheem, Kareem, Largent-Milnes, Tally M., Rhee, Peter, Vanderah, Todd W., Joseph, Bellal

Journal:

Journal of Trauma and Acute Care Surgery

Year:

2017

Language:

english

File:

PDF, 1.79 MB

english, 2017

33

Temperature Differentially Facilitates Spontaneous but Not Evoked Glutamate Release from Cranial Visceral Primary Afferents

Fawley, Jessica A., Hofmann, Mackenzie E., Largent-Milnes, Tally M., Andresen, Michael C., Tell, Fabien

Journal:

Year:

2015

Language:

english

File:

PDF, 769 KB

english, 2015

34

Glial neuroimmune signaling in opioid reward

Zhang, Hong, Largent-Milnes, Tally M., Vanderah, Todd W.

Journal:

Brain Research Bulletin

Year:

2020

File:

PDF, 2.93 MB

2020

35

Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities

Nair, Padma, Yamamoto, Takashi, Largent-Milnes, Tally M., Cowell, Scott, Kulkarni, Vinod, Moye, Sharif, Navratilova, Edita, Davis, Peg, Ma, Shou-Wu, Vanderah, Todd W., Lai, Josephine, Porreca, Frank,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 571 KB

english, 2013

36

Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats

S. Tumati, W.R. Roeske, T.M. Largent-Milnes, T.W. Vanderah, E.V. Varga

Journal:

Journal of Neuroscience Methods

Year:

2011

Language:

english

File:

PDF, 562 KB

english, 2011

37

A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain

Edwards, Katie A., Havelin, Joshua J., Mcintosh, Mary I., Ciccone, Haley A., Pangilinan, Kathlene, Imbert, Ian, Largent-Milnes, Tally M., King, Tamara, Vanderah, Todd W., Streicher, John M.

Journal:

The Journal of Pain

Year:

2018

Language:

english

File:

PDF, 736 KB

english, 2018

38

Recently patented and promising ORL-1 ligands: where have we been and where are we going?

Largent-Milnes, Tally M, Vanderah, Todd W

Journal:

Expert Opinion on Therapeutic Patents

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

39

(277) The cystine-glutamate antiporter system xc- drives tumor cell glutamate release and cancer-induced bone pain

Slosky, L., BassiriRad, N., Symons-Liguori, A., Forte, B., Bui, L., Largent-Milnes, T., Vanderah, T.

Journal:

The Journal of Pain

Year:

2015

Language:

english

File:

PDF, 97 KB

english, 2015

40

Blocking CRMP2 SUMOylation reverses neuropathic pain

Moutal, A, Dustrude, E T, Largent-Milnes, T M, Vanderah, T W, Khanna, M, Khanna, R

Journal:

Molecular Psychiatry

Year:

2017

Language:

english

File:

PDF, 349 KB

english, 2017

41

Oxycodone Plus Ultra-Low-Dose Naltrexone Attenuates Neuropathic Pain and Associated μ-Opioid Receptor–Gs Coupling

Tally M. Largent-Milnes, Wenhong Guo, Hoau-Yan Wang, Lindsay H. Burns, Todd W. Vanderah

Journal:

The Journal of Pain

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

42

Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E2 in the spinal cord

Timothy M. Marshall, David S. Herman, Tally M. Largent-Milnes, Hamid Badghisi, Konstantina Zuber, Shannon C. Holt, Josephine Lai, Frank Porreca, Todd W. Vanderah

Journal:

Year:

2012

Language:

english

File:

PDF, 590 KB

english, 2012

43

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss

Alysia N. Lozano-Ondoua, Courtney Wright, Anna Vardanyan, Tamara King, Tally M. Largent-Milnes, Mark Nelson, Juan Miguel Jimenez-Andrade, Patrick W. Mantyh, Todd W. Vanderah

Journal:

Year:

2010

Language:

english

File:

PDF, 862 KB

english, 2010

44

(354) Estrogen induces cortical spreading depression (CSD) associated with migraine aura in awake, freely moving female rats

Sandweiss, A., Skinner, D., Vanderah, T., Largent-Milnes, T.

Journal:

The Journal of Pain

Year:

2015

Language:

english

File:

PDF, 140 KB

english, 2015

45

The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain

Thompson, A.L., Grenald, S.A., Ciccone, H.A., BassiriRad, N., Niphakis, M.J., Cravatt, B.F., Largent-Milnes, T.M., Vanderah, T.W.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2020

File:

PDF, 940 KB

2020

46

Novel d-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral κ-opioid receptors,

Todd W. Vanderah, Tally Largent-Milnes, Josephine Lai, Frank Porreca, Richard A. Houghten, Frédérique Menzaghi, Kazimierz Wisniewski, Jacek Stalewski, Javier Sueiras-Diaz, Robert Galyean, Claudio Scht

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

47

Animal models for opioid addiction drug discovery

Grenald, Shaness A, Largent-Milnes, Tally M, Vanderah, Todd W

Journal:

Expert Opinion on Drug Discovery

Year:

2014

Language:

english

File:

PDF, 277 KB

english, 2014

48

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

François-Moutal, Liberty, Wang, Yue, Moutal, Aubin, Cottier, Karissa E., Melemedjian, Ohannes K., Yang, Xiaofang, Wang, Yuying, Ju, Weina, Largent-Milnes, Tally M., Khanna, May, Vanderah, Todd W., Kha

Journal:

Year:

2015

Language:

english

File:

PDF, 2.06 MB

english, 2015

49

Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats

Hegarty, Deborah M., Hermes, Sam M., Largent-Milnes, Tally M., Aicher, Sue A.

Journal:

Journal of Chemical Neuroanatomy

Year:

2014

Language:

english

File:

PDF, 3.10 MB

english, 2014

50

External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1

Hofmann, M. E., Largent-Milnes, T. M., Fawley, J. A., Andresen, M. C.

Journal:

Journal of Neurophysiology

Year:

2014

Language:

english

File:

PDF, 641 KB

english, 2014

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