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1

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

Ali Salanti, Trine Staalsoe, Thomas Lavstsen, Anja T. R. Jensen, M. P. Kordai Sowa, David E. Arnot, Lars Hviid, Thor G. Theander

Journal:

Molecular Microbiology

Year:

2003

Language:

english

File:

PDF, 272 KB

english, 2003

2

Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens

J. SOERLI, L. BARFOD, T. LAVSTSEN, N. L. BERNASCONI, A. LANZAVECCHIA, L. HVIID

Journal:

Parasite Immunology

Year:

2009

Language:

english

File:

PDF, 249 KB

english, 2009

3

Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

Christian W. Wang, Pamela A. Magistrado, Morten A. Nielsen, Thor G. Theander, Thomas Lavstsen

Journal:

International Journal for Parasitology

Year:

2009

Language:

english

File:

PDF, 969 KB

english, 2009

4

Response to Duffy and Tham: Transcription and coregulation of multigene families in Plasmodium falciparum

Sarah Sharp, Louisa McRobert, Colin Sutherland, Thomas Lavstsen

Journal:

Trends in Parasitology

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

5

The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer

Christian W. Wang, Cornelus C. Hermsen, Robert W. Sauerwein, David E. Arnot, Thor G. Theander, Thomas Lavstsen

Journal:

Parasitology International

Year:

2009

Language:

english

File:

PDF, 392 KB

english, 2009

6

Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface

Tibúrcio, Marta, Silvestrini, Francesco, Bertuccini, Lucia, Sander, Adam Frederik, Turner, Louise, Lavstsen, Thomas, Alano, Pietro

Journal:

Cellular Microbiology

Year:

2013

Language:

english

File:

PDF, 840 KB

english, 2013

7

Severe malaria is associated with parasite binding to endothelial protein C receptor

Turner, Louise, Lavstsen, Thomas, Berger, Sanne S., Wang, Christian W., Petersen, Jens E. V., Avril, Marion, Brazier, Andrew J., Freeth, Jim, Jespersen, Jakob S., Nielsen, Morten A., Magistrado, Pamel

Journal:

Year:

2013

Language:

english

File:

PDF, 403 KB

english, 2013

8

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum

Jiang, Lubin, Mu, Jianbing, Zhang, Qingfeng, Ni, Ting, Srinivasan, Prakash, Rayavara, Kempaiah, Yang, Wenjing, Turner, Louise, Lavstsen, Thomas, Theander, Thor G., Peng, Weiqun, Wei, Guiying, Jing, Qi

Journal:

Year:

2013

Language:

english

File:

PDF, 1.42 MB

english, 2013

9

Evidence forin vitroandin vivoexpression of the conserved VAR3 (type 3)plasmodium falciparumerythrocyte membrane protein 1

Christian W Wang, Thomas Lavstsen, Dominique C Bengtsson…

Journal:

Malaria Journal

Year:

2012

Language:

english

File:

PDF, 574 KB

english, 2012

10

Changes invargene mRNA levels during erythrocytic development in two phenotypically distinctPlasmodium falciparumparasites

Madeleine Dahlbäck, Thomas Lavstsen, Ali Salanti, Lars Hviid…

Journal:

Malaria Journal

Year:

2007

Language:

english

File:

PDF, 1.39 MB

english, 2007

11

Expression ofPlasmodium falciparumerythrocyte membrane protein 1 in experimentally infected humans

Thomas Lavstsen, Pamela Magistrado, Cornelus C Hermsen, Ali Salanti…

Journal:

Malaria Journal

Year:

2005

Language:

english

File:

PDF, 1.02 MB

english, 2005

12

Sub-grouping ofPlasmodium falciparum3D7vargenes based on sequence analysis of coding and non-coding regions

Thomas Lavstsen, Ali Salanti, Anja TR Jensen, David E Arnot…

Journal:

Malaria Journal

Year:

2003

Language:

english

File:

PDF, 689 KB

english, 2003

13

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

Lavstsen, T., Turner, L., Saguti, F., Magistrado, P., Rask, T. S., Jespersen, J. S., Wang, C. W., Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, E., Gilbert, M. T. P., Lus

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 829 KB

english, 2012

14

Malaria's deadly grip: cytoadhesion of Plasmodium falciparum -infected erythrocytes

Smith, Joseph D., Rowe, J. Alexandra, Higgins, Matthew K., Lavstsen, Thomas

Journal:

Cellular Microbiology

Year:

2013

Language:

english

File:

PDF, 328 KB

english, 2013

15

Differential Expression of var Gene Groups Is Associated with Morbidity Caused by Plasmodium falciparum Infection in Tanzanian Children

Rottmann, M., Lavstsen, T., Mugasa, J. P., Kaestli, M., Jensen, A. T. R., Muller, D., Theander, T., Beck, H.-P.

Journal:

Infection and Immunity

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

16

Programmed Transcription of the var Gene Family, but Not of stevor, in Plasmodium falciparum Gametocytes

Sharp, S., Lavstsen, T., Fivelman, Q. L., Saeed, M., McRobert, L., Templeton, T. J., Jensen, A. T. R., Baker, D. A., Theander, T. G., Sutherland, C. J.

Journal:

Eukaryotic Cell

Year:

2006

Language:

english

File:

PDF, 416 KB

english, 2006

17

Positive Selection of Plasmodium falciparum Parasites With Multiple var2csa-Type PfEMP1 Genes During the Course of Infection in Pregnant Women

Sander, A. F., Salanti, A., Lavstsen, T., Nielsen, M. A., Theander, T. G., Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E., Taylor, D. W.

Journal:

The Journal of Infectious Diseases

Year:

2011

Language:

english

File:

PDF, 146 KB

english, 2011

18

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

Sander, A. F., Lavstsen, T., Rask, T. S., Lisby, M., Salanti, A., Fordyce, S. L., Jespersen, J. S., Carter, R., Deitsch, K. W., Theander, T. G., Pedersen, A. G., Arnot, D. E.

Journal:

Nucleic Acids Research

Year:

2014

Language:

english

File:

PDF, 4.35 MB

english, 2014

19

IgG Antibodies to Endothelial Protein C Receptor-Binding Cysteine-Rich Interdomain Region Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 Are Acquired Early in Life in Individuals Exposed to Malaria

Turner, Louise, Lavstsen, Thomas, Mmbando, Bruno P., Wang, Christian W., Magistrado, Pamela A., Vestergaard, Lasse S., Ishengoma, Deus S., Minja, Daniel T. R., Lusingu, John P., Theander, Thor G., Ada

Journal:

Infection and Immunity

Year:

2015

Language:

english

File:

PDF, 1.55 MB

english, 2015

20

Sequential, Ordered Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 Domains

Cham, G. K. K., Turner, L., Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, A. T. R., Salanti, A., Lavstsen, T., Theander, T. G.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

21

Hierarchical, Domain Type-Specific Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Tanzanian Children

Cham, G. K. K., Turner, L., Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, A. T. R., Lavstsen, T., Hviid, L., Duffy, P. E., Theander, T. G.

Journal:

Infection and Immunity

Year:

2010

Language:

english

File:

PDF, 1.90 MB

english, 2010

22

Surface Co-Expression of Two Different PfEMP1 Antigens on Single Plasmodium falciparum-Infected Erythrocytes Facilitates Binding to ICAM1 and PECAM1

Joergensen, Louise, Bengtsson, Dominique C., Bengtsson, Anja, Ronander, Elena, Berger, Sanne S., Turner, Louise, Dalgaard, Michael B., Cham, Gerald K. K., Victor, Michala E., Lavstsen, Thomas, Theande

Journal:

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

23

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

Lau, Clinton K.Y., Turner, Louise, Jespersen, Jakob S., Lowe, Edward D., Petersen, Bent, Wang, Christian W., Petersen, Jens E.V., Lusingu, John, Theander, Thor G., Lavstsen, Thomas, Higgins, Matthew K

Journal:

Cell Host & Microbe

Year:

2015

Language:

english

File:

PDF, 3.42 MB

english, 2015

24

Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer

Rask, Thomas S., Hansen, Daniel A., Theander, Thor G., Gorm Pedersen, Anders, Lavstsen, Thomas, Eisen, Jonathan A.

Journal:

PLoS Computational Biology

Year:

2010

Language:

english

File:

PDF, 2.15 MB

english, 2010

25

An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria

Amulic, Borko, Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten A., Deitsch, Kirk W., Beck, Hans-Peter

Journal:

Year:

2009

Language:

english

File:

PDF, 654 KB

english, 2009

26

Immunoglobulin G Antibody Reactivity to a Group A Plasmodium falciparum Erythrocyte Membrane Protein 1 and Protection from P. falciparum Malaria

Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, T., Turner, L., Hviid, L., Jensen, A. T. R., Theander, T. G.

Journal:

Infection and Immunity

Year:

2007

Language:

english

File:

PDF, 135 KB

english, 2007

27

The role of EPCR in the pathogenesis of severe malaria

Mosnier, Laurent O., Lavstsen, Thomas

Journal:

Thrombosis Research

Year:

2016

Language:

english

File:

PDF, 1008 KB

english, 2016

28

Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria

Duffy, Michael F., Noviyanti, Rintis, Tsuboi, Takafumi, Feng, Zhi-Ping, Trianty, Leily, Sebayang, Boni F., Takashima, Eizo, Sumardy, Fransisca, Lampah, Daniel A., Turner, Louise, Lavstsen, Thomas, Fow

Journal:

Malaria Journal

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

29

Plasmodium falciparum PHIST Proteins Contribute to Cytoadherence and Anchor PfEMP1 to the Host Cell Cytoskeleton

Oberli, Alexander, Zurbrügg, Laura, Rusch, Sebastian, Brand, Françoise, Butler, Madeleine E., Day, Jemma L., Cutts, Erin E., Lavstsen, Thomas, Vakonakis, Ioannis, Beck, Hans-Peter

Journal:

Cellular Microbiology

Year:

2016

Language:

english

File:

PDF, 1.34 MB

english, 2016

30

The structural basis for CD36 binding by the malaria parasite

Hsieh, Fu-Lien, Turner, Louise, Bolla, Jani Reddy, Robinson, Carol V., Lavstsen, Thomas, Higgins, Matthew K.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.27 MB

english, 2016

31

Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1

Tuikue Ndam, Nicaise, Moussiliou, Azizath, Lavstsen, Thomas, Kamaliddin, Claire, Jensen, Anja T. R., Mama, Atikatou, Tahar, Rachida, Wang, Christian W., Jespersen, Jakob S., Alao, Jules M., Gamain, Be

Journal:

The Journal of Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 232 KB

english, 2017

32

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

Shabani, Estela, Opoka, Robert O., Bangirana, Paul, Park, Gregory S., Vercellotti, Gregory M., Guan, Weihua, Hodges, James S., Lavstsen, Thomas, John, Chandy C.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

33

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

Jespersen, Jakob S, Wang, Christian W, Mkumbaye, Sixbert I, Minja, Daniel TR, Petersen, Bent, Turner, Louise, Petersen, Jens EV, Lusingu, John PA, Theander, Thor G, Lavstsen, Thomas

Journal:

EMBO Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 582 KB

english, 2016

34

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

Shabani, Estela, Hanisch, Benjamin, Opoka, Robert O., Lavstsen, Thomas, John, Chandy C.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

35

A vaccine targeted specifically to prevent cerebral malaria – is there hope?

Hviid, Lars, Lavstsen, Thomas, Jensen, Anja TR

Journal:

Expert Review of Vaccines

Year:

2018

Language:

english

File:

PDF, 835 KB

english, 2018

36

Plasmodium falciparum Transcriptome Analysis Reveals Pregnancy Malaria Associated Gene Expression

Tuikue Ndam, Nicaise, Bischoff, Emmanuel, Proux, Caroline, Lavstsen, Thomas, Salanti, Ali, Guitard, Juliette, Nielsen, Morten A., Coppée, Jean-Yves, Gaye, Alioune, Theander, Thor, David, Peter H., Del

Journal:

Year:

2008

Language:

english

File:

PDF, 300 KB

english, 2008

37

Antibodies against PfEMP1, RIFIN, MSP3 and GLURP Are Acquired during Controlled Plasmodium falciparum Malaria Infections in Naïve Volunteers

Turner, Louise, Wang, Christian W., Lavstsen, Thomas, Mwakalinga, Steven B., Sauerwein, Robert W., Hermsen, Cornelus C., Theander, Thor G., Snounou, Georges

Journal:

Year:

2011

Language:

english

File:

PDF, 699 KB

english, 2011

38

Expression of the Domain Cassette 8 Plasmodium falciparum Erythrocyte Membrane Protein 1 Is Associated with Cerebral Malaria in Benin

Bertin, Gwladys I., Lavstsen, Thomas, Guillonneau, François, Doritchamou, Justin, Wang, Christian W., Jespersen, Jakob S., Ezimegnon, Sem, Fievet, Nadine, Alao, Maroufou J., Lalya, Francis, Massougbod

Journal:

Year:

2013

Language:

english

File:

PDF, 400 KB

english, 2013

39

Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant

Petersen, Jens E. V., Bouwens, Eveline A. M., Tamayo, Ibai, Turner, Louise, Wang, Christian W., Stins, Monique, Theander, Thor G., Hermida, José, Mosnier, Laurent O., Lavstsen, Thomas

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 530 KB

english, 2015

40

Immunization with recombinant P. falciparum erythrocyte membrane protein 1 CIDRα1 domains induces domain subtype inhibitory antibodies

Turner, Louise, Theander, Thor G, Lavstsen, Thomas

Journal:

Infection and Immunity

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

41

Plasmodium falciparum-CD36 structure-function relationships defined by ortholog scanning mutagenesis

Cabrera, Ana, Neculai, Dante, Tran, Vanessa, Lavstsen, Thomas, Turner, Louise, Kain, Kevin C

Journal:

The Journal of Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.21 MB

english, 2018

42

Meta-analysis of Plasmodium falciparum var Signatures Contributing to Severe Malaria in African Children and Indian Adults

Duffy, Fergal, Bernabeu, Maria, Babar, Prasad H., Kessler, Anne, Wang, Christian W., Vaz, Marina, Chery, Laura, Mandala, Wilson L., Rogerson, Stephen J., Taylor, Terrie E., Seydel, Karl B., Lavstsen,

Journal:

Year:

2019

Language:

english

File:

PDF, 1.47 MB

english, 2019

43

Meta-analysis of Plasmodium falciparum var Signatures Contributing to Severe Malaria in African Children and Indian Adults

Duffy, Fergal, Bernabeu, Maria, Babar, Prasad H., Kessler, Anne, Wang, Christian W., Vaz, Marina, Chery, Laura, Mandala, Wilson L., Rogerson, Stephen J., Taylor, Terrie E., Seydel, Karl B., Lavstsen,

Journal:

Year:

2019

File:

PDF, 1.47 MB

2019

44

Dynamics of PfEMP1 antibody profile from birth to 12 months of age in Beninese infants

Moussiliou, A, Turner, L, Cottrell, G, Doritchamou, J, GbÃ©dandÃ©, K, Fievet, N, Luty, A J F, Massougbodji, A, Theander, T G, Deloron, P, Lavstsen, T, Tuikue Ndam, N

Journal:

The Journal of Infectious Diseases

Year:

2020

Language:

english

File:

PDF, 1.44 MB

english, 2020

45

Immunization with virus-like particles conjugated to CIDRÎ±1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies

Harmsen, Charlotte, Turner, Louise, Thrane, Susan, Sander, Adam F., Theander, Thor G., Lavstsen, Thomas

Journal:

Malaria Journal

Year:

2020

File:

PDF, 1.42 MB

2020

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