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1

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

Zachos, Nicholas C, Kovbasnjuk, Olga, Foulke-Abel, Jennifer, In, Julie, Blutt, Sarah E, De Jonge, Hugo R, Estes, Mary K, Donowitz, Mark

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

2

Enteral nutritional therapy for induction of remission in Crohn's disease

Narula, Neeraj, Dhillon, Amit, Zhang, Dongni, Sherlock, Mary E, Tondeur, Melody, Zachos, Mary

Journal:

Cochrane database of systematic reviews

Year:

2018

Language:

english

File:

PDF, 896 KB

english, 2018

3

Effect of Exclusive Enteral Nutrition and Corticosteroid Induction Therapy on the Gut Microbiota of Pediatric Patients with Inflammatory Bowel Disease

Hart, Lara, Farbod, Yasamin, Szamosi, Jake C., Yamamoto, Mai, Britz-McKibbin, Philip, Halgren, Camilla, Zachos, Mary, Pai, Nikhil

Journal:

Year:

2020

File:

PDF, 4.83 MB

2020

4

Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: Potential contributors to IBD-associated diarrhea

Sean Sullivan, Philip Alex, Themos Dassopoulos, Nicholas C. Zachos, Christine Iacobuzio-Donahue, Mark Donowitz, Steven R. Brant, Carmen Cuffari, Mary L. Harris, Lisa Wu Datta, Laurie Conklin, Yueping

Journal:

Inflammatory Bowel Diseases

Year:

2009

Language:

english

File:

PDF, 2.30 MB

english, 2009

5

Assessment of knowledge in adolescents with inflammatory bowel disease using a novel transition tool

Eric I. Benchimol, Thomas D. Walters, Miriam Kaufman, Karen Frost, Karoline Fiedler, Zenaida Chinea, Mary Zachos

Journal:

Inflammatory Bowel Diseases

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

6

IL-10R polymorphisms are associated with very-early-onset ulcerative colitis

Christopher J. Moran, Thomas D. Walters, Cong-Hui Guo, Subra Kugathasan, Christoph Klein, Dan Turner, Victorien M. Wolters, Robert H. Bandsma, Marialena Mouzaki, Mary Zachos, NEOPICS, Jacob C. Langer,

Journal:

Inflammatory Bowel Diseases

Year:

2012

Language:

english

File:

PDF, 1.37 MB

english, 2012

7

Chk1 Is Required for Spindle Checkpoint Function

George Zachos, Elizabeth J. Black, Mark Walker, Mary T. Scott, Paola Vagnarelli, William C. Earnshaw, David A.F. Gillespie

Journal:

Developmental Cell

Year:

2007

Language:

english

File:

PDF, 1.71 MB

english, 2007

8

Tissue viability imaging for assessment of pharmacologically induced vasodilation and vasoconstriction in human skin

Lars J. Petersen, Helle D. Zacho, Ann Marie Lyngholm, Lars Arendt-Nielsen

Journal:

Microvascular Research

Year:

2010

Language:

english

File:

PDF, 709 KB

english, 2010

9

S1220 Distinct Cytokine Patterns As Effective Indicators of Disease Activity and Severity in IBD

Philip Alex, Nicholas C. Zachos, Laurie S. Conklin, John H. Kwon, Mary L. Harris, Theodore M. Bayless, Michael Centola, Xuhang Li

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

10

Early Paleogene warm climates and biosphere dynamics: Meeting in Göteborg makes progress in deciphering the dynamics of past greenhouse worlds

Sloan, Lisa Cirbus, Schmitz, Birger, Aubry, Marie-Pierre, Zachos, James

Journal:

Paleoceanography

Year:

1999

Language:

english

File:

PDF, 207 KB

english, 1999

11

Development, Validation, and Evaluation of a Pediatric Ulcerative Colitis Activity Index: A Prospective Multicenter Study

Dan Turner, Anthony R. Otley, David Mack, Jeffrey Hyams, J. de Bruijne, Krista Uusoue, Thomas D. Walters, Mary Zachos, Petar Mamula, Dorcas E. Beaton, A. Hillary Steinhart, Anne M. Griffiths

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 482 KB

english, 2007

12

Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls

Benedetto Simone, Valerio De Stefano, Emanuele Leoncini, Jeppe Zacho, Ida Martinelli, Joseph Emmerich, Elena Rossi, Aaron R. Folsom, Wassim Y. Almawi, Pierre Y. Scarabin, Martin den Heijer, Mary Cushm

Journal:

European Journal of Epidemiology

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

13

401 Human Ex Vivo Enteroid Culture As a Functional Model of Human Small Intestinal Physiology and Pathophysiology: Inhibition of Na+ Absorption by cAMP and Rotavirus and Stimulation of Cl− Secretion by cAMP

Zachos, Nicholas C., In, Julie, Foulke-Abel, Jennifer, Middendorp, Sabine, de Jonge, Hugo, Zeng, X.L., Ettayebi, Khalil, Estes, Mary K., Donowitz, Mark, Kovbasnjuk, Olga

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 193 KB

english, 2013

14

Mo1939 Rotavirus Inhibits NHE3 Activity via Clathrin-Independent Endocytosis Resulting in Increased NHE3 Degradation

Zachos, Nicholas C., Foulke-Abel, Jennifer, Biswas, Rajat S., In, Julie, Wang, Peng, Brown, Alex, Kovbasnjuk, Olga, Estes, Mary K.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 205 KB

english, 2014

15

190 Human Small Intestinal Enteroids Enable Mechanistic Studies of cAMPInduced Changes in Intracellular pH

Foulke-Abel, Jennifer, In, Julie, Zachos, Nicholas C., Kovbasnjuk, Olga, Ettayebi, Khalil, de Jonge, Hugo, Estes, Mary K., Donowitz, Mark

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 54 KB

english, 2014

16

W1177 Infliximab-Induced Psoriasis in Pediatric Crohn Disease; Experience of This Paradoxical Skin Manifestation At a Tertiary Centre and a Potential Association with a Variation in the IL-23r Gene

Sherlock, Mary E., Walters, Thomas D., Zachos, Mary, Muise, Aleixo, Griffiths, Anne M.

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

17

Preface & summary

Schmitz, Birger, Aubry, Marie-Pierre, Zachos, James

Journal:

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

18

Tubulointerstitial nephritis as an extraintestinal manifestation of Crohn's disease

Waters, Aoife M, Zachos, Mary, Herzenberg, Andrew M, Harvey, Elizabeth, Rosenblum, Norman D

Journal:

Nature Clinical Practice Nephrology

Year:

2008

Language:

english

File:

PDF, 374 KB

english, 2008

19

Mo1766 Mucus Produced by Stem Cell Derived Human Colonoids Is an Early Target in Enterohemorrhagic E. coli Infection

In, Julie, Foulke-Abel, Jennifer, Zachos, Nicholas C., Hansen, Anne-Marie, Kaper, James B., Blutt, Sarah E., Estes, Mary K., Donowitz, Mark, Kovbasnjuk, Olga

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 475 KB

english, 2015

20

Tu1401 Differential Intracellular Calcium Inhibition of NHE3 Activity

Biswas, Rajat S., Wang, Peng, Kovbasnjuk, Olga, Donowitz, Mark, Estes, Mary K., Zachos, Nicholas C.

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 76 KB

english, 2015

21

Sa1252 Systematic Review and Meta-Analysis: Enteral Nutritional Therapy for Induction of Remission in Crohn's Disease

Narula, Neeraj, Dhillon, Amit, Sherlock, Mary, Zachos, Mary

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 728 KB

english, 2015

22

Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology

Foulke-Abel, Jennifer, In, Julie, Yin, Jianyi, Zachos, Nicholas C., Kovbasnjuk, Olga, Estes, Mary K., de Jonge, Hugo, Donowitz, Mark

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 10.93 MB

english, 2015

23

Genetic structure and effective population sizes in European red deer ( Cervus elaphus ) at a continental scale: insights from microsatellite DNA

Zachos, Frank E., Frantz, Alain C., Kuehn, Ralph, Bertouille, Sabine, Colyn, Marc, Niedzialkowska, Magdalena, Pérez-González, Javier, Skog, Anna, Sprĕm, Nikica, Flamand, Marie-Christine

Journal:

Journal of Heredity

Year:

2016

Language:

english

File:

PDF, 818 KB

english, 2016

24

DEVELOPMENT OF A PEDIATRIC ULCERATIVE COLITIS ACTIVITY INDEX (PUCAI)

Turner, Dan, Otley, Anthony, deBruijne, Joep, Mack, David, Uusoue, Krista, Zachos, Mary, Mamula, Petar, Hyams, Jeff, Griffiths, Anne M.

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2006

Language:

english

File:

PDF, 697 KB

english, 2006

25

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids

In, Julie, Foulke-Abel, Jennifer, Zachos, Nicholas C., Hansen, Anne-Marie, Kaper, James B., Bernstein, Harris D., Halushka, Marc, Blutt, Sarah, Estes, Mary K., Donowitz, Mark, Kovbasnjuk, Olga

Journal:

CMGH Cellular and Molecular Gastroenterology and Hepatology

Year:

2016

Language:

english

File:

PDF, 5.81 MB

english, 2016

26

Enteral feeding and Crohn disease

Zachos, Mary, Griffiths, Anne M.

Journal:

Current Opinion in Gastroenterology

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

27

977 Human Colonoids As a Model for Shiga Toxin Producing E. coli (STEC)-Induced Intestinal Epithelial Injury and Regeneration

In, Julie, Zachos, Nicholas C., Foulke-Abel, Jennifer, Blutt, Sarah, Estes, Mary, Bernstein, Harris D., Donowitz, Mark, Kovbasnjuk, Olga

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 132 KB

english, 2016

28

541 Rotavirus Infection in Patients Is Associated With Altered Trafficking of Apical Membrane Transport Proteins

Baetz, Nicholas W., Gupta, Akshita, Kapoor, Anirudh, Kovbasnjuk, Olga, Turner, Jerrold, Donowitz, Mark, Estes, Mary, Zachos, Nicholas C.

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 129 KB

english, 2016

29

Sa2070 A Qualitative Analysis of Barriers and Facilitators to an Effective Bowel Preparation for Colonoscopy in Children

Hart, Lara, Nael, Humaira, Wickert, Natasha, Mbuagbaw, Lawrence, Zachos, Mary

Journal:

Gastrointestinal Endoscopy

Year:

2016

Language:

english

File:

PDF, 182 KB

english, 2016

30

Human enteroids: preclinical models of non-inflammatory diarrhea

Kovbasnjuk, Olga, Zachos, Nicholas C, In, Julie, Foulke-Abel, Jennifer, Ettayebi, Khalil, Hyser, Joseph M, Broughman, James R, Zeng, Xi-Lei, Middendorp, Sabine, de Jonge, Hugo R, Estes, Mary K, Donowi

Journal:

Stem Cell Research & Therapy

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

31

Cochrane Database of Systematic Reviews (Reviews) || Enteral nutritional therapy for induction of remission in Crohn's disease

Year:

1996

Language:

english

File:

PDF, 491 KB

english, 1996

32

P-119 Transition Experience from Pediatric to Adult IBD Care

Romanova, Anna, Armstrong, David, Brill, Herbert, Chauhan, Usha, Halder, Smita, Moayyedi, Paul, Tse, Frances, Zachos, Mary, Marshall, John

Journal:

Inflammatory Bowel Diseases

Year:

2013

Language:

english

File:

PDF, 57 KB

english, 2013

33

Infliximab-Induced Psoriasis and Psoriasiform Skin Lesions in Pediatric Crohn Disease and a Potential Association With IL-23 Receptor Polymorphisms

Sherlock, Mary E., Walters, Thomas, Tabbers, Merit M., Frost, Karen, Zachos, Mary, Muise, Aleixo, Pope, Elena, Griffiths, Anne M.

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2013

Language:

english

File:

PDF, 233 KB

english, 2013

34

Human mini-guts: new insights into intestinal physiology and host–pathogen interactions

In, Julie G., Foulke-Abel, Jennifer, Estes, Mary K., Zachos, Nicholas C., Kovbasnjuk, Olga, Donowitz, Mark

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

35

The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology

Yu, Huimin, Hasan, Nesrin M., In, Julie G., Estes, Mary K., Kovbasnjuk, Olga, Zachos, Nicholas C., Donowitz, Mark

Journal:

Annual Review of Physiology

Year:

2017

Language:

english

File:

PDF, 959 KB

english, 2017

36

Effectiveness of Targeted Food Elimination Diet in Management of Pediatric Eosinophilic Esophagitis (EoE): A Retrospective Review.

Thiru, Shalini, Vakaljan, Stephanie L., Sherlock, Mary E., Zachos, Mary, Ratcliffe, Elyanne, Issenman, Robert, Pai, Nikhil, Ohayon, Jason A.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 128 KB

english, 2017

37

Gastrointestinal microphysiological systems

Blutt, Sarah E, Broughman, James R, Zou, Winnie, Zeng, Xi-Lei, Karandikar, Umesh C, In, Julie, Zachos, Nicholas C, Kovbasnjuk, Olga, Donowitz, Mark, Estes, Mary K

Journal:

Experimental Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 862 KB

english, 2017

38

In Vitro Modeling of Human Enterohepatic Circulation Using Stem Cell-Derived Ileal Enteroids and Primary Cultures of Hepatocytes

Blutt, Sarah E., Broughman, James R., Vernetti, Larry, Tessier, Mary Elizabeth M., Crawford, Sue E., Zeng, Xi-Lei, Savidge, Tor C., Bissig, Karl-Dimiter, Foulke-Abel, Jennifer D., Zachos, Nicholas C.,

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 266 KB

english, 2017

39

Using genetic tools to estimate the prevalence of non-native red deer ( Cervus elaphus ) in a Western European population

Frantz, Alain C., Zachos, Frank E., Bertouille, Sabine, Eloy, Marie-Christine, Colyn, Marc, Flamand, Marie-Christine

Journal:

Ecology and Evolution

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

40

Barriers and Facilitators to a Good Bowel Preparation for Colonoscopy in Children

Hart, Lara, Nael, Humaira, Longmire, Natasha M., Zachos, Mary

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2018

Language:

english

File:

PDF, 110 KB

english, 2018

41

Author's response to “Depth of inflammation in Crohn's disease”

Waters, Aoife M, Zachos, Mary, Herzenberg, Andrew M, Harvey, Elizabeth, Rosenblum, Norman D

Journal:

Nature Clinical Practice Nephrology

Year:

2009

File:

PDF, 34 KB

2009

42

Constraints and opportunities for integrating preparation for reuse in the Danish WEEE management system

Zacho, Kristina Overgaard, Bundgaard, Anja Marie, Mosgaard, Mette Albert

Journal:

Resources, Conservation and Recycling

Year:

2018

Language:

english

File:

PDF, 383 KB

english, 2018

43

Drug-induced esophageal injury with an occult vascular ring

Guttman, Orlee R, Zachos, Mary

Journal:

Paediatrics & child health

Year:

2011

Language:

english

File:

PDF, 800 KB

english, 2011

44

Clinical and Laboratory Characteristics Are Associated With Biologic Therapy Use in Pediatric Inflammatory Bowel Disease: A Retrospective Cohort Study

Sherlock, Mary E, Zachos, Mary, Issenman, Robert M, Mulder, Daniel J

Journal:

Journal of the Canadian Association of Gastroenterology

Year:

2020

File:

PDF, 690 KB

2020

45

Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

In, Julie G., Yin, Jianyi, Atanga, Roger, Doucet, Michele, Cole, Robert N., DeVine, Lauren, Donowitz, Mark, Zachos, Nicholas C., Blutt, Sarah E., Estes, Mary K., Kovbasnjuk, Olga

Journal:

Year:

2020

File:

PDF, 714 KB

2020

46

Intestinal stem cell derived enteroids from morbidly obese patients preserve obesity-related phenotypes: elevated glucose absorption and gluconeogenesis

Hasan, Nesrin M., Johnson, Kelli F., Yin, Jianyi, Baetz, Nicholas W., Fayad, Lea, Sherman, Vadim, Blutt, Sarah E., Estes, Mary K., Kumbhari, Vivek, Zachos, Nicholas C., Kovbasnjuk, Olga

Journal:

Molecular Metabolism

Year:

2020

File:

PDF, 2.64 MB

2020