Punit P Seth: search on Z-Library

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51

On the Stereochemistry of the Dihydropyrone Diels−Alder Reaction

Seth, Punit P., Totah, Nancy I.

Journal:

Organic Letters

Year:

1999

Language:

english

File:

PDF, 70 KB

english, 1999

52

Studies toward the Tricyclic Core of Phomactin A. Synthesis of the Reduced Furanochroman Subunit

Seth, Punit P., Totah, Nancy I.

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 47 KB

english, 2000

53

Configuration of the 5′-Methyl Group Modulates the Biophysical and Biological Properties of Locked Nucleic Acid (LNA) Oligonucleotides

Seth, Punit P., Allerson, Charles R., Siwkowski, Andrew, Vasquez, Guillermo, Berdeja, Andres, Migawa, Michael T., Gaus, Hans, Prakash, Thazha P., Bhat, Balkrishen, Swayze, Eric E.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.52 MB

english, 2010

54

Comparison of Duplex Stabilizing Properties of 2′-Fluorinated Nucleic Acid Analogues with Furanose and Non-Furanose Sugar Rings

Østergaard, Michael E., Dwight, Timothy, Berdeja, Andres, Swayze, Eric E., Jung, Michael E., Seth, Punit P.

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

55

Synthesis of 1-Oxadecalones via the Lewis Acid Catalyzed Dihydropyrone Diels−Alder Reaction

Seth, Punit P., Totah, Nancy I.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 64 KB

english, 1999

56

Structure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAs

Pallan, Pradeep S., Allerson, Charles R., Berdeja, Andres, Seth, Punit P., Swayze, Eric E., Prakash, Thazha P., Egli, Martin

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

57

Synthesis and Duplex-Stabilizing Properties of Fluorinated N -Methanocarbathymidine Analogues Locked in the C3′- endo Conformation

Jung, Michael E., Dwight, Timothy A., Vigant, Frederic, Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 522 KB

english, 2014

58

Synthesis and Duplex-Stabilizing Properties of Fluorinated N -Methanocarbathymidine Analogues Locked in the C3′- endo Conformation

Jung, Michael E., Dwight, Timothy A., Vigant, Frederic, Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Angewandte Chemie

Year:

2014

Language:

english

File:

PDF, 511 KB

english, 2014

59

Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals

Seth, Punit P, Jazayeri, Ali, Yu, Jeff, Allerson, Charles R, Bhat, Balkrishen, Swayze, Eric E

Journal:

Molecular Therapy — Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

60

Biophysical and Biological Characterization of Hairpin and Molecular Beacon RNase H Active Antisense Oligonucleotides

Østergaard, Michael E., Thomas, George, Koller, Erich, Southwell, Amber L., Hayden, Michael R., Seth, Punit P.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 471 KB

english, 2015

61

18F-Fluoride PET/CT for detection of bone metastasis in patients with renal cell carcinoma

Sharma, Punit, Karunanithi, Sellam, Chakraborty, Partha S., Kumar, Rajeev, Seth, Amlesh, Julka, Pramod K., Bal, Chandrasekhar, Kumar, Rakesh

Journal:

Nuclear Medicine Communications

Year:

2014

Language:

english

File:

PDF, 492 KB

english, 2014

62

Solid‐Phase Synthesis of N ‐Aryl‐ N ′‐Carboalkoxy Guanidines by the Mitsunobu Reaction of Fmoc‐Guanidines

Robinson, Dale E., Seth, Punit P., Jefferson, Elizabeth A.

Journal:

Synthetic Communications

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

63

Therapeutic targeting of HCV internal ribosomal entry site RNA

Davis, Darrell R, Seth, Punit P

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2010

Language:

english

File:

PDF, 627 KB

english, 2010

64

An Unusual Intramolecular Acetal Alkylation

Gao, Xiuchun, Seth, Punit P., Bitok, John K., Totah, Nancy I.

Journal:

Year:

2005

Language:

english

File:

PDF, 93 KB

english, 2005

65

Inhibitor-induced structural change in the HCV IRES domain IIa RNA

Ryan B. Paulsen, Punit P. Seth, Eric E. Swayze, Richard H. Griffey, Jack J. Skalicky, Thomas E. Cheatham, III, Darrell R. Davis and Dinshaw J. Patel

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.65 MB

english, 2010

66

Design, synthesis, and duplex-stabilizing properties of conformationally constrained tricyclic analogues of LNA

Giacometti, Robert D., Salinas, Juan C., Østergaard, Michael E., Swayze, Eric E., Seth, Punit P., Hanessian, Stephen

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 2.87 MB

english, 2016

67

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

Miller, Colton M., Donner, Aaron J., Blank, Emma E., Egger, Andrew W., Kellar, Brianna M., Østergaard, Michael E., Seth, Punit P., Harris, Edward N.

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 4.75 MB

english, 2016

68

A convenient synthesis of 5′-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid

Migawa, Michael T., Prakash, Thazha P., Vasquez, Guillermo, Wan, W. Brad, Yu, Jinghua, Kinberger, Garth A., Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 692 KB

english, 2016

69

Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice

Yu, Rosie Z, Graham, Mark J, Post, Noah, Riney, Stan, Zanardi, Thomas, Hall, Shannon, Burkey, Jennifer, Shemesh, Colby S, Prakash, Thazha P, Seth, Punit P, Swayze, Eric E, Geary, Richard S, Wang, Yanf

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 690 KB

english, 2016

70

Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys

Shemesh, Colby S, Yu, Rosie Z, Gaus, Hans J, Greenlee, Sarah, Post, Noah, Schmidt, Karsten, Migawa, Michael T, Seth, Punit P, Zanardi, Thomas A, Prakash, Thazha P, Swayze, Eric E, Henry, Scott P, Wang

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 4.02 MB

english, 2016

71

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Prakash, Thazha P., Kinberger, Garth A., Murray, Heather M., Chappell, Alfred, Riney, Stan, Graham, Mark J., Lima, Walt F., Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 614 KB

english, 2016

72

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

Kinberger, Garth A., Prakash, Thazha P., Yu, Jinghua, Vasquez, Guillermo, Low, Audrey, Chappell, Alfred, Schmidt, Karsten, Murray, Heather M., Gaus, Hans, Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 475 KB

english, 2016

73

Allele-Selective Inhibition of Mutant Huntingtin with 2-Thio- and C5- Triazolylphenyl-Deoxythymidine-Modified Antisense Oligonucleotides

Østergaard, Michael E., Kumar, Pawan, Nichols, Josh, Watt, Andrew, Sharma, Pawan K., Nielsen, Poul, Seth, Punit P.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

74

ChemInform Abstract: Synthesis and Biophysical Properties of Constrained D-Altritol Nucleic Acids (cANA).

Migawa, Michael T., Prakash, Thazha P., Vasquez, Guillermo, Seth, Punit P., Swayze, Eric E.

Journal:

Year:

2014

File:

PDF, 22 KB

2014

75

Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides

Østergaard, Michael E., Nichols, Josh, Dwight, Timothy A., Lima, Walt, Jung, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2017

Language:

english

File:

PDF, 3.46 MB

english, 2017

76

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology

Posey, Karen L., Coustry, Francoise, Veerisetty, Alka C., Hossain, Mohammad, Gattis, Danielle, Booten, Sheri, Alcorn, Joseph L., Seth, Punit P., Hecht, Jacqueline T.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

77

Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver

Donner, Aaron J., Wancewicz, Edward V., Murray, Heather M., Greenlee, Sarah, Post, Noah, Bell, Melanie, Lima, Walt F., Swayze, Eric E., Seth, Punit P.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2017

Language:

english

File:

PDF, 870 KB

english, 2017

78

Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity

Prakash, Thazha P., Lima, Walt F., Murray, Heather M., Li, Wenyu, Kinberger, Garth A., Chappell, Alfred E., Gaus, Hans, Seth, Punit P., Bhat, Balkrishen, Crooke, Stanley T., Swayze, Eric E.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 85 KB

english, 2017

79

Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes

Tanowitz, Michael, Hettrick, Lisa, Revenko, Alexey, Kinberger, Garth A., Prakash, Thazha P., Seth, Punit P.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 11.49 MB

english, 2017

80

Endosomal Escape of ASOs Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation

Miller, Colton M., Wan, W. Brad, Seth, Punit P., Harris, Edward N.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2018

Language:

english

File:

PDF, 625 KB

english, 2018

81

Structural determinants for the interactions of chemically modified nucleic acids with the Stabilin-2 clearance receptor

Gaus, Hans, Miller, Colton M., Seth, Punit P, Harris, Edward N.

Journal:

Year:

2018

Language:

english

File:

PDF, 443 KB

english, 2018

82

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor

Schmidt, Karsten, Prakash, Thazha P., Donner, Aaron J., Kinberger, Garth A., Gaus, Hans J., Low, Audrey, Østergaard, Michael E., Bell, Melanie, Swayze, Eric E., Seth, Punit P.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 903 KB

english, 2017

83

Studies directed toward the asialoglycoprotein receptor mediated delivery of 5-fluoro-2′-deoxyuridine for hepatocellular carcinoma

Rico, Lorena, Østergaard, Michael E., Bell, Melanie, Seth, Punit P., Hanessian, Stephen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 383 KB

english, 2018

84

Conception and Synthesis of Oxabicyclic Nucleoside Phosphonates as Internucleotidic Phosphate Surrogates in Antisense Oligonucleotide Constructs

Salinas, Juan C., Yu, Jeff, Østergaard, Michael, Seth, Punit P., Hanessian, Stephen

Journal:

Organic Letters

Year:

2018

Language:

english

File:

PDF, 934 KB

english, 2018

85

Evaluation of the Effect of 2’-O-Methyl, Fluoro Hexitol, Bicyclo and Morpholino Nucleic Acid Modifications on Potency of GalNAc Conjugated Antisense Oligonucleotides in Mice

Prakash, Thazha P., Yu, Jinghua, Kinberger, Garth A., Low, Audrey, Jackson, Michaela, Rigo, Frank, Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 850 KB

english, 2018

86

S-Acyl-2-Thioethyl: A Convenient Base-Labile Protecting Group for the Synthesis of siRNAs Containing 5′-Vinylphosphonate

Nikan, Mehran, Li, Wenyu, Kinberger, Garth, Seth, Punit, Swayze, Eric, Prakash, Thazha

Journal:

Year:

2019

Language:

english

File:

PDF, 1.22 MB

english, 2019

87

Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate

Satake, Noriko, Duong, Connie, Yoshida, Sakiko, Oestergaard, Michael, Chen, Cathy, Peralta, Rachael, Guo, Shuling, Seth, Punit P, Li, Yueju, Beckett, Laurel, Chung, Jong, Nolta, Jan, Nitin, Nitin, Tus

Journal:

Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

88

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

Prakash, Thazha P, Mullick, Adam E, Lee, Richard G, Yu, Jinghua, Yeh, Steve T, Low, Audrey, Chappell, Alfred E, Østergaard, Michael E, Murray, Sue, Gaus, Hans J, Swayze, Eric E, Seth, Punit P

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 3.73 MB

english, 2019

89

Design And Synthesis Of An Azabicyclic Nucleoside Phosphoramidite For Oligonucleotide Antisense Constructs

Salinas, Juan C., Seth, Punit P., Hanessian, Stephen

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2019

Language:

english

File:

PDF, 2.36 MB

english, 2019

90

Design And Synthesis Of An Azabicyclic Nucleoside Phosphoramidite For Oligonucleotide Antisense Constructs

Salinas, Juan C., Seth, Punit P., Hanessian, Stephen

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2019

File:

PDF, 2.36 MB

2019

91

MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma

Sakiko Yoshida, MD., Duong, Connie, Oestergaard, Michael, Fazio, Michael, Chen, Cathy, Peralta, Rachael, Guo, Shuling, Seth, Punit P, Li, Yueju, Beckett, Laurel, Nitin, Nitin, Satake, Noriko

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2019

Language:

english

File:

PDF, 8.95 MB

english, 2019

92

MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma

Sakiko Yoshida, MD., Duong, Connie, Oestergaard, Michael, Fazio, Michael, Chen, Cathy, Peralta, Rachael, Guo, Shuling, Seth, Punit P, Li, Yueju, Beckett, Laurel, Nitin, Nitin, Satake, Noriko

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2019

File:

PDF, 8.95 MB

2019

93

Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice

Chappell, Alfred E, Gaus, Hans J, Berdeja, Andres, Gupta, Ruchi, Jo, Minji, Prakash, Thazha P, Oestergaard, Michael, Swayze, Eric E, Seth, Punit P

Journal:

Nucleic Acids Research

Year:

2020

Language:

english

File:

PDF, 2.81 MB

english, 2020

94

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins

Hyjek-SkÅadanowska, Malwina, Vickers, Timothy, NapiÃ³rkowska, Agnieszka, Anderson, Brooke, Tanowitz, Michael, Crooke, Stanley T., Liang, Xue-hai, Seth, Punit P, Nowotny, Marcin

Journal:

Journal of the American Chemical Society

Year:

2020

Language:

english

File:

PDF, 1.51 MB

english, 2020

95

Interaction of ASOs with PC4 is highly influenced by the cellular environment and ASO chemistry

Vickers, Timothy A., Migawa, Michael, Seth, Punit P, Crooke, Stanley T

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 3.84 MB

2020

96

IFN-Î³ and CIITA modulate IL-6 expression in skeletal muscle

Adhikari, Abhinav, Cobb, Brittan, Eddington, Seth, Becerra, Nathalie, Kohli, Punit, Pond, Amber, Davie, Judith

Journal:

Year:

2020

File:

PDF, 666 KB

2020

97

Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide

Nikan, Mehran, Tanowitz, Michael, Dwyer, Chrissa A., Jackson, Michaela, Gaus, Hans, Swayze, Eric, Rigo, Frank, Seth, Punit P, Prakash, Thazha P.

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.04 MB

2020

98

The Interaction of Phosphorothioate Containing RNA Targeted Drugs with Proteins is a Critical Determinant of The Therapeutic Effects of These Agents

Crooke, Stanley, Seth, Punit P, Vickers, Timothy A., Liang, Xue-hai

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 1.44 MB

2020

99

Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1

Hyjek-SkÅadanowska, Malwina, StasiÅska, Anna R., NapiÃ³rkowska, Agnieszka, BartÅomiejczak, Aneta, Seth, Punit P., Chmielewski, Marcin K., Nowotny, Marcin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2020

File:

PDF, 2.02 MB

2020

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