Punit P. Seth: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

51

Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals

Seth, Punit P., Siwkowski, Andrew, Allerson, Charles R., Vasquez, Guillermo, Lee, Sam, Prakash, Thazha P., Wancewicz, Edward V., Witchell, Donna, Swayze, Eric E.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 454 KB

english, 2009

52

Differential Effects on Allele Selective Silencing of Mutant Huntingtin by Two Stereoisomers of α,β-Constrained Nucleic Acid

Østergaard, Michael E., Gerland, Béatrice, Escudier, Jean-Marc, Swayze, Eric E., Seth, Punit P.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

53

Allele-Selective Inhibition of Mutant Huntingtin with 2-Thio- and C5- Triazolylphenyl-Deoxythymidine-Modified Antisense Oligonucleotides

Østergaard, Michael E., Kumar, Pawan, Nichols, Josh, Watt, Andrew, Sharma, Pawan K., Nielsen, Poul, Seth, Punit P.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

54

MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma

Sakiko Yoshida, MD., Duong, Connie, Oestergaard, Michael, Fazio, Michael, Chen, Cathy, Peralta, Rachael, Guo, Shuling, Seth, Punit P, Li, Yueju, Beckett, Laurel, Nitin, Nitin, Satake, Noriko

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2019

Language:

english

File:

PDF, 8.95 MB

english, 2019

55

Optimizing the antibacterial activity of a lead structure discovered by ‘SAR by MS’ technology

Elizabeth A. Jefferson, Punit P. Seth, Dale E. Robinson, Dana K. Winter, Alycia Miyaji, Lisa M. Risen, Stephen A. Osgood, Myra Bertrand, Eric E. Swayze

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 326 KB

english, 2004

56

Synthesis of bicyclic proline analogs using a formal [3 + 2] intramolecular aziridine-allylsilane cycloaddition reaction

Stephen C. Bergmeier, Susan L. Fundy, Punit P. Seth

Journal:

Year:

1999

Language:

english

File:

PDF, 897 KB

english, 1999

57

Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2′-Fluoro RNA

Seth, Punit P., Yu, Jinghua, Jazayeri, Ali, Pallan, Pradeep S., Allerson, Charles R, Østergaard, Michael E., Liu, Fengwu, Herdewijn, Piet, Egli, Martin, Swayze, Eric E.

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 2.06 MB

english, 2012

58

Configuration of the 5′-Methyl Group Modulates the Biophysical and Biological Properties of Locked Nucleic Acid (LNA) Oligonucleotides

Seth, Punit P., Allerson, Charles R., Siwkowski, Andrew, Vasquez, Guillermo, Berdeja, Andres, Migawa, Michael T., Gaus, Hans, Prakash, Thazha P., Bhat, Balkrishen, Swayze, Eric E.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.52 MB

english, 2010

59

18F-Fluoride PET/CT for detection of bone metastasis in patients with renal cell carcinoma

Sharma, Punit, Karunanithi, Sellam, Chakraborty, Partha S., Kumar, Rajeev, Seth, Amlesh, Julka, Pramod K., Bal, Chandrasekhar, Kumar, Rakesh

Journal:

Nuclear Medicine Communications

Year:

2014

Language:

english

File:

PDF, 492 KB

english, 2014

60

Replacing the 2′-oxygen with an exocyclic methylene group reverses the stabilization effects of α-l-LNA

Punit P. Seth, Charles R. Allerson, Andres Berdeja, Eric E. Swayze

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 422 KB

english, 2011

61

The Dihydropyrone Diels–Alder Reaction: Development and Application to the Synthesis of Highly Functionalized 1-Oxa-4-decalones

Punit P. Seth, Deqi Chen, Junquan Wang, Xiuchun Gao, Nancy I. Totah

Journal:

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

62

Aziridine−Allylsilane-Mediated Total Synthesis of (−)-Yohimbane

Bergmeier, Stephen C., Seth, Punit P.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 109 KB

english, 1999

63

Design, synthesis, and duplex-stabilizing properties of conformationally constrained tricyclic analogues of LNA

Giacometti, Robert D., Salinas, Juan C., Østergaard, Michael E., Swayze, Eric E., Seth, Punit P., Hanessian, Stephen

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 2.87 MB

english, 2016

64

Conception and Synthesis of Oxabicyclic Nucleoside Phosphonates as Internucleotidic Phosphate Surrogates in Antisense Oligonucleotide Constructs

Salinas, Juan C., Yu, Jeff, Østergaard, Michael, Seth, Punit P., Hanessian, Stephen

Journal:

Organic Letters

Year:

2018

Language:

english

File:

PDF, 934 KB

english, 2018

65

S-Acyl-2-Thioethyl: A Convenient Base-Labile Protecting Group for the Synthesis of siRNAs Containing 5′-Vinylphosphonate

Nikan, Mehran, Li, Wenyu, Kinberger, Garth, Seth, Punit, Swayze, Eric, Prakash, Thazha

Journal:

Year:

2019

Language:

english

File:

PDF, 1.22 MB

english, 2019

66

Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1

Hyjek-SkÅadanowska, Malwina, StasiÅska, Anna R., NapiÃ³rkowska, Agnieszka, BartÅomiejczak, Aneta, Seth, Punit P., Chmielewski, Marcin K., Nowotny, Marcin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2020

File:

PDF, 2.02 MB

2020

67

Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes

Tanowitz, Michael, Hettrick, Lisa, Revenko, Alexey, Kinberger, Garth A., Prakash, Thazha P., Seth, Punit P.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 11.49 MB

english, 2017

68

Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate

Satake, Noriko, Duong, Connie, Yoshida, Sakiko, Oestergaard, Michael, Chen, Cathy, Peralta, Rachael, Guo, Shuling, Seth, Punit P, Li, Yueju, Beckett, Laurel, Chung, Jong, Nolta, Jan, Nitin, Nitin, Tus

Journal:

Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

69

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

Prakash, Thazha P, Mullick, Adam E, Lee, Richard G, Yu, Jinghua, Yeh, Steve T, Low, Audrey, Chappell, Alfred E, Østergaard, Michael E, Murray, Sue, Gaus, Hans J, Swayze, Eric E, Seth, Punit P

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 3.73 MB

english, 2019

70

Design And Synthesis Of An Azabicyclic Nucleoside Phosphoramidite For Oligonucleotide Antisense Constructs

Salinas, Juan C., Seth, Punit P., Hanessian, Stephen

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2019

File:

PDF, 2.36 MB

2019

71

ChemInform Abstract: Stereochemistry of the Dihydropyrone Diels—Alder Reaction.

Punit P. Seth, Nancy I. Totah

Journal:

Year:

2000

File:

PDF, 29 KB

2000

72

Identification of 2-Aminobenzimidazole Dimers as Antibacterial Agents.

Punit P. Seth, Elizabeth A. Jefferson, Lisa M. Risen, Stephen A. Osgood

Journal:

Year:

2003

File:

PDF, 107 KB

2003

73

Studies toward the Tricyclic Core of Phomactin A. Synthesis of the Reduced Furanochroman Subunit

Seth, Punit P., Totah, Nancy I.

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 47 KB

english, 2000

74

Comparison of Duplex Stabilizing Properties of 2′-Fluorinated Nucleic Acid Analogues with Furanose and Non-Furanose Sugar Rings

Østergaard, Michael E., Dwight, Timothy, Berdeja, Andres, Swayze, Eric E., Jung, Michael E., Seth, Punit P.

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

75

Inhibitor-induced structural change in the HCV IRES domain IIa RNA

Ryan B. Paulsen, Punit P. Seth, Eric E. Swayze, Richard H. Griffey, Jack J. Skalicky, Thomas E. Cheatham, III, Darrell R. Davis and Dinshaw J. Patel

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.65 MB

english, 2010

76

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology

Posey, Karen L., Coustry, Francoise, Veerisetty, Alka C., Hossain, Mohammad, Gattis, Danielle, Booten, Sheri, Alcorn, Joseph L., Seth, Punit P., Hecht, Jacqueline T.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

77

ChemInform Abstract: A General Method for Deprotection of N-Toluenesulfonyl Aziridines Using Sodium Naphthalenide.

Stephen C. Bergmeier, Punit P. Seth

Journal:

Year:

1999

File:

PDF, 29 KB

1999

78

Biaryl guanidine inhibitors of in vitro HCV-IRES activity

Elizabeth A. Jefferson, Punit P. Seth, Dale E. Robinson, Dana K. Winter, Alycia Miyaji, Stephen A. Osgood, Eric E. Swayze, Lisa M. Risen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 300 KB

english, 2004

79

Solid‐Phase Synthesis of N ‐Aryl‐ N ′‐Carboalkoxy Guanidines by the Mitsunobu Reaction of Fmoc‐Guanidines

Robinson, Dale E., Seth, Punit P., Jefferson, Elizabeth A.

Journal:

Synthetic Communications

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

80

Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice

Yu, Rosie Z, Graham, Mark J, Post, Noah, Riney, Stan, Zanardi, Thomas, Hall, Shannon, Burkey, Jennifer, Shemesh, Colby S, Prakash, Thazha P, Seth, Punit P, Swayze, Eric E, Geary, Richard S, Wang, Yanf

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 690 KB

english, 2016

81

Synthesis of cis - and trans -α- l -[4.3.0]Bicyclo-DNA Monomers for Antisense Technology: Methods for the Diastereoselective Formation of Bicyclic Nucleosides

Hanessian, Stephen, Schroeder, Benjamin R., Merner, Bradley L., Chen, Bin, Swayze, Eric E., Seth, Punit P.

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

82

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor

Schmidt, Karsten, Prakash, Thazha P., Donner, Aaron J., Kinberger, Garth A., Gaus, Hans J., Low, Audrey, Østergaard, Michael E., Bell, Melanie, Swayze, Eric E., Seth, Punit P.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 903 KB

english, 2017

83

Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice

Chappell, Alfred E, Gaus, Hans J, Berdeja, Andres, Gupta, Ruchi, Jo, Minji, Prakash, Thazha P, Oestergaard, Michael, Swayze, Eric E, Seth, Punit P

Journal:

Nucleic Acids Research

Year:

2020

Language:

english

File:

PDF, 2.81 MB

english, 2020

84

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins

Hyjek-SkÅadanowska, Malwina, Vickers, Timothy, NapiÃ³rkowska, Agnieszka, Anderson, Brooke, Tanowitz, Michael, Crooke, Stanley T., Liang, Xue-hai, Seth, Punit P, Nowotny, Marcin

Journal:

Journal of the American Chemical Society

Year:

2020

Language:

english

File:

PDF, 1.51 MB

english, 2020

85

Synthesis and Duplex-Stabilizing Properties of Fluorinated N -Methanocarbathymidine Analogues Locked in the C3′- endo Conformation

Jung, Michael E., Dwight, Timothy A., Vigant, Frederic, Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Angewandte Chemie

Year:

2014

Language:

english

File:

PDF, 511 KB

english, 2014

86

Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys

Shemesh, Colby S, Yu, Rosie Z, Gaus, Hans J, Greenlee, Sarah, Post, Noah, Schmidt, Karsten, Migawa, Michael T, Seth, Punit P, Zanardi, Thomas A, Prakash, Thazha P, Swayze, Eric E, Henry, Scott P, Wang

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 4.02 MB

english, 2016

87

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Prakash, Thazha P., Kinberger, Garth A., Murray, Heather M., Chappell, Alfred, Riney, Stan, Graham, Mark J., Lima, Walt F., Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 614 KB

english, 2016

88

ChemInform Abstract: Aziridine—Allylsilane-Mediated Total Synthesis of (-)-Yohimbane.

Stephen C. Bergmeier, Punit P. Seth

Journal:

Year:

1999

File:

PDF, 33 KB

1999

89

Aryl urea analogs with broad-spectrum antibacterial activity

Punit P. Seth, Ray Ranken, Dale E. Robinson, Stephen A. Osgood, Lisa M. Risen, Elizabeth L. Rodgers, Michael T. Migawa, Elizabeth A. Jefferson, Eric E. Swayze

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

90

A convenient synthesis of 5′-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid

Migawa, Michael T., Prakash, Thazha P., Vasquez, Guillermo, Wan, W. Brad, Yu, Jinghua, Kinberger, Garth A., Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 692 KB

english, 2016

91

Design And Synthesis Of An Azabicyclic Nucleoside Phosphoramidite For Oligonucleotide Antisense Constructs

Salinas, Juan C., Seth, Punit P., Hanessian, Stephen

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2019

Language:

english

File:

PDF, 2.36 MB

english, 2019

92

Interaction of ASOs with PC4 is highly influenced by the cellular environment and ASO chemistry

Vickers, Timothy A., Migawa, Michael, Seth, Punit P, Crooke, Stanley T

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 3.84 MB

2020

93

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

Kinberger, Garth A., Prakash, Thazha P., Yu, Jinghua, Vasquez, Guillermo, Low, Audrey, Chappell, Alfred, Schmidt, Karsten, Murray, Heather M., Gaus, Hans, Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 475 KB

english, 2016

94

Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide

Nikan, Mehran, Tanowitz, Michael, Dwyer, Chrissa A., Jackson, Michaela, Gaus, Hans, Swayze, Eric, Rigo, Frank, Seth, Punit P, Prakash, Thazha P.

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.04 MB

2020

95

On the Stereochemistry of the Dihydropyrone Diels−Alder Reaction

Seth, Punit P., Totah, Nancy I.

Journal:

Organic Letters

Year:

1999

Language:

english

File:

PDF, 70 KB

english, 1999

96

Structural determinants for the interactions of chemically modified nucleic acids with the Stabilin-2 clearance receptor

Gaus, Hans, Miller, Colton M., Seth, Punit P, Harris, Edward N.

Journal:

Year:

2018

Language:

english

File:

PDF, 443 KB

english, 2018

97

Studies directed toward the asialoglycoprotein receptor mediated delivery of 5-fluoro-2′-deoxyuridine for hepatocellular carcinoma

Rico, Lorena, Østergaard, Michael E., Bell, Melanie, Seth, Punit P., Hanessian, Stephen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 383 KB

english, 2018

98

Efficient Solution Phase Synthesis of 2-(N-Acyl)-aminobenzimidazoles.

Punit P. Seth, Dale E. Robinson, Elizabeth A. Jefferson, Eric E. Swayze

Journal:

Year:

2002

File:

PDF, 29 KB

2002

99

Evaluation of the Effect of 2’-O-Methyl, Fluoro Hexitol, Bicyclo and Morpholino Nucleic Acid Modifications on Potency of GalNAc Conjugated Antisense Oligonucleotides in Mice

Prakash, Thazha P., Yu, Jinghua, Kinberger, Garth A., Low, Audrey, Jackson, Michaela, Rigo, Frank, Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 850 KB

english, 2018

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски