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151

Investigating Protein-Protein Interaction Networks with Force Spectroscopy

Farrance, Oliver E., Kaminska, Renata, Housden, Nicholas G., Derrington, Sasha R., Kleanthous, Colin, Radford, Sheena E., Brockwell, David J.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

152

Dissecting the Effects of Periplasmic Chaperones on the In Vitro Folding of the Outer Membrane Protein PagP

McMorran, Lindsay M., Bartlett, Alice I., Huysmans, Gerard H.M., Radford, Sheena E., Brockwell, David J.

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

153

Protein Folding || Insights into Protein Folding Using Physical Techniques: Studies of Lysozyme and α -lactalbumin

Sheena E. Radford and Christopher M. Dobson

Journal:

Philosophical Transactions Biological Sciences

Year:

1995

Language:

english

File:

PDF, 1.35 MB

english, 1995

154

Synthesis, Characterization and Applications of a Perdeuterated Amphipol

Giusti, Fabrice, Rieger, Jutta, Catoire, Laurent J., Qian, Shuo, Calabrese, Antonio N., Watkinson, Thomas G., Casiraghi, Marina, Radford, Sheena E., Ashcroft, Alison E., Popot, Jean-Luc

Journal:

Journal of Membrane Biology

Year:

2014

Language:

english

File:

PDF, 1.46 MB

english, 2014

155

Ultraviolet Resonance Raman Studies Reveal the Environment of Tryptophan and Tyrosine Residues in the Native and Partially Folded States of the E Colicin-Binding Immunity Protein Im7 †

Rodriguez-Mendieta, Iñigo R., Spence, Graham R., Gell, Christopher, Radford, Sheena E., Smith, D. Alastair

Journal:

Year:

2005

Language:

english

File:

PDF, 238 KB

english, 2005

156

Sulfate-Induced Effects in the On-Pathway Intermediate of the Bacterial Immunity Protein Im7* †

Cobos, Eva S., Radford, Sheena E.

Journal:

Year:

2006

Language:

english

File:

PDF, 239 KB

english, 2006

157

Cooperative Elements in Protein Folding Monitored by Electrospray Ionization Mass Spectrometry

Hooke, Shaun D., Eyles, Stephen J., Miranker, Andrew, Radford, Sheena E., Robinson, Carol V., Dobson, Christopher M.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 300 KB

english, 1995

158

Magic Angle Spinning NMR Analysis of β 2 -Microglobulin Amyloid Fibrils in Two Distinct Morphologies

Debelouchina, Galia T., Platt, Geoffrey W., Bayro, Marvin J., Radford, Sheena E., Griffin, Robert G.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 3.37 MB

english, 2010

159

A photochemically induced dynamic nuclear polarization study of denatured state of lysozyme

Broadhurst, R. William, Dobson, Christopher M., Hore, P. J., Radford, Sheena E., Rees, Marion L.

Journal:

Year:

1991

Language:

english

File:

PDF, 951 KB

english, 1991

160

Partially Unfolded Species Populated during Equilibrium Denaturation of the β-Sheet Protein Y74W Apo-Pseudoazurin †

Jones, Susan, Reader, John S., Healy, Maria, Capaldi, Andrew P., Ashcroft, Alison E., Kalverda, Arnout P., Smith, D. Alastair, Radford, Sheena E.

Journal:

Year:

2000

Language:

english

File:

PDF, 250 KB

english, 2000

161

Visualization of Transient Protein-Protein Interactions that Promote or Inhibit Amyloid Assembly

Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.23 MB

english, 2014

162

Ion Mobility Spectrometry–Mass Spectrometry Defines the Oligomeric Intermediates in Amylin Amyloid Formation and the Mode of Action of Inhibitors

Young, Lydia M., Cao, Ping, Raleigh, Daniel P., Ashcroft, Alison E., Radford, Sheena E.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 5.38 MB

english, 2014

163

Covalent Cross-Linking within Supramolecular Peptide Structures

Preston, George W., Radford, Sheena E., Ashcroft, Alison E., Wilson, Andrew J.

Journal:

Analytical Chemistry

Year:

2012

Language:

english

File:

PDF, 4.17 MB

english, 2012

164

Intermolecular Alignment in β 2 -Microglobulin Amyloid Fibrils

Debelouchina, Galia T., Platt, Geoffrey W., Bayro, Marvin J., Radford, Sheena E., Griffin, Robert G.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 406 KB

english, 2010

165

Far-UV Circular Dichroism Reveals a Conformational Switch in a Peptide Fragment from the .beta.-Sheet of Hen Lysozyme

Yang, Jenny Jie, Pitkeathly, Maureen, Radford, Sheena E.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.98 MB

english, 1994

166

Analysis of Amyloid Nanostructures Using Photo-cross-linking: In Situ Comparison of Three Widely Used Photo-cross-linkers

Preston, George W., Radford, Sheena E., Ashcroft, Alison. E., Wilson, Andrew J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 5.25 MB

english, 2014

167

Site-directed mutagenesis and proton NMR spectroscopy of an interdomain segment in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

Texter, Frieda L., Radford, Sheena E., Laue, Ernest D., Perham, Richard N., Miles, John S., Guest, John R.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.59 MB

english, 1988

168

Secondary Structure in the Core of Amyloid Fibrils Formed from Human β 2 m and its Truncated Variant ΔN6

Su, Yongchao, Sarell, Claire J., Eddy, Matthew T., Debelouchina, Galia T., Andreas, Loren B., Pashley, Clare L., Radford, Sheena E., Griffin, Robert G.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 5.47 MB

english, 2014

169

The Refolding of Human Lysozyme: A Comparison with the Structurally Homologous Hen Lysozyme

Hooke, Shaun D., Radford, Sheena E., Dobson, Christopher M.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.05 MB

english, 1994

170

Tertiary Interactions in the Folding Pathway of Hen Lysozyme: Kinetic Studies Using Fluorescent Probes

Itzhaki, Laura S., Evans, Philip A., Dobson, Christopher M., Radford, Sheena E.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.75 MB

english, 1994

171

Comparison of the Refolding Hen Lysozyme from Dimethyl Sulfoxide and Guanidinium Chloride

Kotik, Michael, Radford, Sheena E., Dobson, Christopher M.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.62 MB

english, 1995

172

Kinetic Consequences of the Removal of a Disulfide Bridge on the Folding of Hen Lysozyme

Eyles, Stephen J., Radford, Sheena E., Robinson, Carol V., Dobson, Christopher M.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.98 MB

english, 1994

173

Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

Smith, David P., Anderson, Jon, Plante, Jeffrey, Ashcroft, Alison E., Radford, Sheena E., Wilson, Andrew J., Parker, Martin J.

Journal:

Chemical Communications

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

174

Book Review

Stan Gorski, Sheena E. Radford,

Journal:

Molecular Membrame Biology

Year:

2000

Language:

english

File:

PDF, 86 KB

english, 2000

175

Internal friction of single polypeptide chains at high stretch

Khatri, Bhavin S., Byrne, Katherine, Kawakami, Masaru, Brockwell, David J., Smith, D. Alastair, Radford, Sheena E., McLeish, Tom C. B.

Journal:

Faraday Discussions

Year:

2008

Language:

english

File:

PDF, 771 KB

english, 2008

176

Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP)

Hoffmann, Armin, Nettels, Daniel, Clark, Jennifer, Borgia, Alessandro, Radford, Sheena E., Clarke, Jane, Schuler, Benjamin

Journal:

Physical Chemistry Chemical Physics

Year:

2011

Language:

english

File:

PDF, 4.25 MB

english, 2011

177

Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry

Young, Lydia M., Saunders, Janet C., Mahood, Rachel A., Revill, Charlotte H., Foster, Richard J., Tu, Ling-Hsien, Raleigh, Daniel P., Radford, Sheena E., Ashcroft, Alison E.

Journal:

Nature Chemistry

Year:

2014

Language:

english

File:

PDF, 5.40 MB

english, 2014

178

Effects of hydration on the mechanical response of individual collagen fibrils

Grant, Colin A., Brockwell, David J., Radford, Sheena E., Thomson, Neil H.

Journal:

Applied Physics Letters

Year:

2008

Language:

english

File:

PDF, 457 KB

english, 2008

179

Amphipols Outperform Dodecylmaltoside Micelles in Stabilizing Membrane Protein Structure in the Gas Phase

Calabrese, Antonio N., Watkinson, Thomas G., Henderson, Peter J. F., Radford, Sheena E., Ashcroft, Alison E.

Journal:

Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 3.08 MB

english, 2015

180

Extraction of Accurate Biomolecular Parameters from Single-Molecule Force Spectroscopy Experiments

Farrance, Oliver E., Paci, Emanuele, Radford, Sheena E., Brockwell, David J.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.12 MB

english, 2015

181

Mutational Analysis of the Ability of Resveratrol To Inhibit Amyloid Formation by Islet Amyloid Polypeptide: Critical Evaluation of the Importance of Aromatic–Inhibitor and Histidine–Inhibitor Interactions

Tu, Ling-Hsien, Young, Lydia M., Wong, Amy G., Ashcroft, Alison E., Radford, Sheena E., Raleigh, Daniel P.

Journal:

Year:

2015

Language:

english

File:

PDF, 7.98 MB

english, 2015

182

Using hydroxyl radical footprinting to explore the free energy landscape of protein folding

Calabrese, Antonio N., Ault, James R., Radford, Sheena E., Ashcroft, Alison E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

183

Mass spectrometric methods to analyze the structural organization of macromolecular complexes

Rajabi, Khadijeh, Ashcroft, Alison E., Radford, Sheena E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.79 MB

english, 2015

184

pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers

Tipping, Kevin W., Karamanos, Theodoros K., Jakhria, Toral, Iadanza, Matthew G., Goodchild, Sophia C., Tuma, Roman, Ranson, Neil A., Hewitt, Eric W., Radford, Sheena E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 3.11 MB

english, 2015

185

Force-induced remodelling of proteins and their complexes

Chen, Yun, Radford, Sheena E, Brockwell, David J

Journal:

Current Opinion in Structural Biology

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

186

A Force-Activated Trip Switch Triggers Rapid Dissociation of a Colicin from Its Immunity Protein

Farrance, Oliver E., Hann, Eleanore, Kaminska, Renata, Housden, Nicholas G., Derrington, Sasha R., Kleanthous, Colin, Radford, Sheena E., Brockwell, David J., Thomas, Wendy E.

Journal:

Year:

2013

Language:

english

File:

PDF, 932 KB

english, 2013

187

Detailed evaluation of the performance of microfluidic T mixers using fluorescence and ultraviolet resonance Raman spectroscopy

Masca, Sergiu I., Rodriguez-Mendieta, Iñigo R., Friel, Claire T., Radford, Sheena E., Smith, D. Alastair

Journal:

Review of Scientific Instruments

Year:

2006

Language:

english

File:

PDF, 236 KB

english, 2006

188

Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry

Young, Lydia M., Mahood, Rachel A., Saunders, Janet C., Tu, Ling-Hsien, Raleigh, Daniel P., Radford, Sheena E., Ashcroft, Alison E.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2015

Language:

english

File:

PDF, 4.42 MB

english, 2015

189

ESI-IMS–MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules

Young, Lydia M., Saunders, Janet C., Mahood, Rachel A., Revill, Charlotte H., Foster, Richard J., Ashcroft, Alison E., Radford, Sheena E.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

190

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion

Scarff, Charlotte A., Almeida, Bruno, Fraga, Joana, Macedo-Ribeiro, Sandra, Radford, Sheena E., Ashcroft, Alison E.

Journal:

Molecular & Cellular Proteomics

Year:

2015

Language:

english

File:

PDF, 3.57 MB

english, 2015

191

Avoidance of Epimerization in the Synthesis of Peptide Thioesters Using Fmoc Protection

Nagalingam, Anil, Radford, Sheena, Warriner, Stuart

Journal:

Year:

2007

Language:

english

File:

PDF, 93 KB

english, 2007

192

Symptoms and Quadriceps Fatigability after Walking and Cycling in Chronic Obstructive Pulmonary Disease

Man, William D.-C., Soliman, Mohamed G. G., Gearing, Johanne, Radford, Sheena G., Rafferty, Gerrard F., Gray, Barry J., Polkey, Michael I., Moxham, John

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

193

Assessing the causes and consequences of co-polymerization in amyloid formation

Sarell, Claire J, Stockley, Peter G, Radford, Sheena E

Journal:

Year:

2013

Language:

english

File:

PDF, 868 KB

english, 2013

194

Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?

Tipping, Kevin W., van Oosten-Hawle, Patricija, Hewitt, Eric W., Radford, Sheena E.

Journal:

Trends in Biochemical Sciences

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

195

Substrate protein folds while it is bound to the ATP-independent chaperone Spy

Stull, Frederick, Koldewey, Philipp, Humes, Julia R, Radford, Sheena E, Bardwell, James C A

Journal:

Nature Structural and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

196

An in vivo platform for identifying inhibitors of protein aggregation

Saunders, Janet C, Young, Lydia M, Mahood, Rachel A, Jackson, Matthew P, Revill, Charlotte H, Foster, Richard J, Smith, D Alastair, Ashcroft, Alison E, Brockwell, David J, Radford, Sheena E

Journal:

Nature Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.71 MB

english, 2015

197

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation

Mark M. Chen, Alice I. Bartlett, Paul S. Nerenberg, Claire T. Friel, Christian P. R. Hackenberger, Collin M. Stultz, Sheena E. Radford and Barbara Imperiali

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

198

Fibril fragmentation in amyloid assembly and cytotoxicity

Xue, Wei-Feng, Hellewell, Andrew L., Hewitt, Eric W., Radford, Sheena E.

Journal:

Year:

2010

Language:

english

File:

PDF, 856 KB

english, 2010

199

Comparison of the aggregation of homologous β2-microglobulin variants reveals protein solubility as a key determinant of amyloid formation

Pashley, Clare L., Hewitt, Eric W., Radford, Sheena E.

Journal:

Journal of Molecular Biology

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

200

Systematic analysis of the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry

Watkinson, Thomas G., Calabrese, Antonio N., Giusti, Fabrice, Zoonens, Manuela, Radford, Sheena E., Ashcroft, Alison E.

Journal:

International Journal of Mass Spectrometry

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015