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1

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

Topalian, Suzanne L., Hodi, F. Stephen, Brahmer, Julie R., Gettinger, Scott N., Smith, David C., McDermott, David F., Powderly, John D., Carvajal, Richard D., Sosman, Jeffrey A., Atkins, Michael B., L

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 684 KB

english, 2012

2

Inside life of melanoma cell signaling, molecular insights, and therapeutic targets

Jeffrey A. Sosman, Kim A. Margolin

Journal:

Current Oncology Reports

Year:

2009

Language:

english

File:

PDF, 387 KB

english, 2009

3

Non-genomic and Immune Evolution of Melanoma Acquiring MAPKi Resistance

Hugo, Willy, Shi, Hubing, Sun, Lu, Piva, Marco, Song, Chunying, Kong, Xiangju, Moriceau, Gatien, Hong, Aayoung, Dahlman, Kimberly B., Johnson, Douglas B., Sosman, Jeffrey A., Ribas, Antoni, Lo, Roger

Journal:

Year:

2015

Language:

english

File:

PDF, 6.27 MB

english, 2015

4

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

Motzer, Robert J., Escudier, Bernard, McDermott, David F., George, Saby, Hammers, Hans J., Srinivas, Sandhya, Tykodi, Scott S., Sosman, Jeffrey A., Procopio, Giuseppe, Plimack, Elizabeth R., Castellan

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 551 KB

english, 2015

5

CheckMate 025 Randomized Phase 3 Study: Outcomes by Key Baseline Factors and Prior Therapy for Nivolumab Versus Everolimus in Advanced Renal Cell Carcinoma

Escudier, Bernard, Sharma, Padmanee, McDermott, David F., George, Saby, Hammers, Hans J., Srinivas, Sandhya, Tykodi, Scott S., Sosman, Jeffrey A., Procopio, Giuseppe, Plimack, Elizabeth R., Castellano

Journal:

European Urology

Year:

2017

Language:

english

File:

PDF, 2.21 MB

english, 2017

6

A Critical Need for Better Cancer Immunotherapy Models: Are Organotypic Tumor Spheroid Cultures the Answer?

Balko, Justin M., Sosman, Jeffrey A.

Journal:

Cancer Discovery

Year:

2018

Language:

english

File:

PDF, 3.85 MB

english, 2018

7

BRAF and MEK inhibitor therapy eliminates nestin expressing melanoma cells in human tumors

Doxie, Deon B, Greenplate, Allison R, Gandelman, Jocelyn S, Diggins, Kirsten E, Roe, Caroline E, Dahlman, Kimberly B, Sosman, Jeffrey A, Kelley, Mark C, Irish, Jonathan M

Journal:

Pigment Cell & Melanoma Research

Year:

2018

Language:

english

File:

PDF, 1.76 MB

english, 2018

8

High-Dose Interferon Alfa-2b Significantly Prolongs Relapse-Free and Overall Survival Compared With the GM2-KLH/QS-21 Vaccine in Patients With Resected Stage IIB-III Melanoma: Results of Intergroup Trial E1694/S9512/C509801

Kirkwood, John M., Ibrahim, Joseph G., Sosman, Jeffrey A., Sondak, Vernon K., Agarwala, Sanjiv S., Ernstoff, Marc S., Rao, Uma

Journal:

Journal of Clinical Oncology

Year:

2001

File:

PDF, 109 KB

2001

9

Phase III Study of Adjuvant Ipilimumab (3 or 10 mg/kg) Versus High-Dose Interferon Alfa-2b for Resected High-Risk Melanoma: North American Intergroup E1609

Tarhini, Ahmad A., Lee, Sandra J., Hodi, F. Stephen, Rao, Uma N. M., Cohen, Gary I., Hamid, Omid, Hutchins, Laura F., Sosman, Jeffrey A., Kluger, Harriett M., Eroglu, Zeynep, Koon, Henry B., Lawrence,

Journal:

Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 653 KB

english, 2019

10

Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy

Basher, Fahmin, Dhar, Payal, Wang, Xin, Wainwright, Derek A., Zhang, Bin, Sosman, Jeffrey, Ji, Zhe, Wu, Jennifer D.

Journal:

Journal of Hematology & Oncology

Year:

2020

File:

PDF, 3.60 MB

2020

11

Induction of human cytotoxic T lymphocytes specific for prostate-specific antigen

Xue, Bao-Hua, Zhang, Yong, Sosman, Jeffrey A., Peace, David J.

Journal:

Year:

1997

Language:

english

File:

PDF, 255 KB

english, 1997

12

the influence of autologous lymphokine-activated killer cell infusions on the toxicity and antitumor effect of repetitive cycles of interleukin-2

Mark R. Albertini, Jeffrey A. Sosman, Jacquelyn A. Hank, Karen H. Moore, Agnes Borchert, Kathleen Schell, Peter C. Kohler, Robin Bechhofer, Barry Storer, Paul M. Sondel

Journal:

Year:

1990

Language:

english

File:

PDF, 863 KB

english, 1990

13

Immunomodulatory effects of high-dose and low-dose interferon α2b in patients with high-risk resected melanoma : The E2690 laboratory corollary of Intergroup Adjuvant Trial E1690

John M. Kirkwood, Thomas Richards, Hassane M. Zarour, Jeffrey Sosman, Marc Ernstoff, Theresa L. Whiteside, Joseph Ibrahim, Ronald Blum, Samuel Wieand, Ruth Mascari

Journal:

Year:

2002

Language:

english

File:

PDF, 177 KB

english, 2002

14

Multicenter Phase II trial of high-dose imatinib mesylate in metastatic melanoma : Significant toxicity with no clinical efficacy

Ken Wyman, Michael B. Atkins, Victor Prieto, Omar Eton, David F. McDermott, Francie Hubbard, Christine Byrnes, Kathleen Sanders, Jeffrey A. Sosman

Journal:

Year:

2006

Language:

english

File:

PDF, 98 KB

english, 2006

15

Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma : A phase II Cytokine Working Group study

Michael B. Atkins, Jeffrey A. Sosman, Sanjiv Agarwala, Theodore Logan, Joseph I. Clark, Marc S. Ernstoff, David Lawson, Janice P. Dutcher, Geoffrey Weiss, Brendan Curti, Kim A. Margolin

Journal:

Year:

2008

Language:

english

File:

PDF, 91 KB

english, 2008

16

Combination targeted therapy in advanced renal cell carcinoma

Jeffrey Sosman, Igor Puzanov

Journal:

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

17

Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508

Joseph I. Clark, James Moon, Laura F. Hutchins, Jeffrey A. Sosman, W. Martin Kast, Diane M. Da Silva, P. Y. Liu, John A. Thompson, Lawrence E. Flaherty, Vernon K. Sondak

Journal:

Year:

2010

Language:

english

File:

PDF, 146 KB

english, 2010

18

A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin αvβ3, ± dacarbazine in patients with stage IV metastatic melanoma

Peter Hersey, Jeffrey Sosman, Steven O'Day, Jon Richards, Agop Bedikian, Rene Gonzalez, William Sharfman, Robert Weber, Theodore Logan, Manuela Buzoianu, Luz Hammershaimb, John M. Kirkwood

Journal:

Year:

2010

Language:

english

File:

PDF, 187 KB

english, 2010

19

A phase 2 trial of complete resection for stage IV melanoma : Results of Southwest Oncology Group Clinical Trial S9430

Jeffrey A. Sosman, James Moon, Ralph J. Tuthill, James A. Warneke, John T. Vetto, Bruce G. Redman, P. Y. Liu, Joseph M. Unger, Lawrence E. Flaherty, Vernon K. Sondak

Journal:

Year:

2011

Language:

english

File:

PDF, 204 KB

english, 2011

20

Severe eosinophilia and hepatocellular carcinoma: An unusual association

Benjamin H. Yuen, Cesar V. Reyes, Paresh A. Rawal, Jeffrey Sosman, Joanne Jensen

Journal:

Diagnostic Cytopathology

Year:

1995

Language:

english

File:

PDF, 476 KB

english, 1995

21

A phase II trial of interleukin-2 in myelodysplastic syndromes

Sucha Nand, Wendy Stock, Patrick Stiff, Jeffrey Sosman, Brenda Martone, Ruta Radvany

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 340 KB

english, 1998

22

Addition of interleukin-2in vitroaugments detection of lymphokine-activated killer activity generatedin vivo

Jacquelyn A. Hank, Gilda Weil-Hillman, Jean E. Surfus, Jeffrey A. Sosman, Paul M. Sondel

Journal:

Cancer Immunology, Immunotherapy

Year:

1990

Language:

english

File:

PDF, 968 KB

english, 1990

23

Induction of Tc2 cells with specificity for prostate-specific antigen from patients with hormone-refractory prostate cancer

Supriya Perambakam, Bao-Hua Xue, Jeffrey A. Sosman, David J. Peace

Journal:

Cancer Immunology, Immunotherapy

Year:

2002

Language:

english

File:

PDF, 174 KB

english, 2002

24

Induction of specific T cell immunity in patients with prostate cancer by vaccination with PSA146–154 peptide

Supriya Perambakam, Sigrun Hallmeyer, Samarth Reddy, Nadim Mahmud, Linda Bressler, Phillip DeChristopher, Delores Mahmud, Rafael Nunez, Jeffrey A. Sosman, David J. Peace

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 391 KB

english, 2006

25

Phase II trial of biochemotherapy with interferon α, dacarbazine, cisplatin and tamoxifen in metastatic melanoma: a Southwest Oncology Group trial

Kim A. Margolin, P. Y. Liu, Joseph M. Unger, William S. Fletcher, Lawrence E. Flaherty, Walter J. Urba, Evan M. Hersh, Laura E. Hutchins, Jeffrey A. Sosman, John W. Smith, Geoffrey R. Weiss, Vernon K.

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1999

Language:

english

File:

PDF, 79 KB

english, 1999

26

B-RAF Inhibitors: An Evolving Role in the Therapy of Malignant Melanoma

Cynthia Shepherd, Igor Puzanov, Jeffrey A. Sosman

Journal:

Current Oncology Reports

Year:

2010

Language:

english

File:

PDF, 208 KB

english, 2010

27

Interactions among human T cell subsets

Yolene Thomas, Jeffrey Sosman, Oscar H. Irigoyen, Linda Rogozinski, Steve M. Friedman, Leonard Chess

Journal:

International Journal of Immunopharmacology

Year:

1981

Language:

english

File:

PDF, 715 KB

english, 1981

28

Interleukin 10-induced thrombocytopenia in normal healthy adult volunteers: evidence for decreased platelet production

Jeffrey A. Sosman, Amit Verma, Steven Moss, Patricia Sorokin, Michael Blend, Basil Bradlow, Nasir Chachlani, David Cutler, Ronald Sabo, Mary Nelson, Edward Bruno, David Gustin, Marlos Viana, Ronald Ho

Journal:

British Journal of Haematology

Year:

2000

Language:

english

File:

PDF, 224 KB

english, 2000

29

Therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: biology, clinical results and future development

Brian I. Rini, Jeffrey A. Sosman, Robert J. Motzer

Journal:

BJU International

Year:

2005

Language:

english

File:

PDF, 84 KB

english, 2005

30

Biological drug duo delivers one-two tumor punch

Sosman, Jeffrey A, Mier, James W

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 290 KB

english, 2003

31

CI-980 in Advanced Melanoma and Hormone Refractory Prostate Cancer

Christopher W. Ryan, Keith L. Shulman, Jon M. Richards, John W. Kugler, Jeffrey A. Sosman, Rafat H. Ansari, Everett E. Vokes, Nicholas J. Vogelzang

Journal:

Investigational New Drugs

Year:

2000

Language:

english

File:

PDF, 49 KB

english, 2000

32

Two phase 2 trials of the novel Akt inhibitor perifosine in patients with advanced renal cell carcinoma after progression on vascular endothelial growth factor-targeted therapy

Daniel C. Cho, Thomas E. Hutson, Wolfram Samlowski, Peter Sportelli, Brad Somer, Paul Richards, Jeffrey A. Sosman, Igor Puzanov, M. Dror Michaelson, Keith T. Flaherty, Robert A. Figlin, Nicholas J. Vo

Journal:

Year:

2012

Language:

english

File:

PDF, 201 KB

english, 2012

33

Results of clinical trials with an allogeneic melanoma tumor cell lysate vaccine: Melacine®

Vernon K Sondak, Jeffrey A Sosman

Journal:

Seminars in Cancer Biology

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

34

Targeting multiple genetic aberrations in isolated tumor cells by spectral fluorescence in situ hybridization

Marilyn L Slovak, Feiyu Zhang, Lucene Tcheurekdjian, Dolores Bobadilla, Victoria Bedell, Daniel A Arber, Diane L Persons, Jeffrey A Sosman, Joyce L Murata-Collins

Journal:

Cancer Detection and Prevention

Year:

2002

Language:

english

File:

PDF, 349 KB

english, 2002

35

Treatment of Advanced Renal Cell Carcinoma with the Combination Bevacizumab/Erlotinib/Imatinib: A Phase I/II Trial

John D. Hainsworth, David R. Spigel, Jeffrey A. Sosman, Howard A. Burris III, Cindy Farley, Heather Cucullu, Kathleen Yost, Lowell L. Hart, Linda Sylvester, David M. Waterhouse, F. Anthony Greco

Journal:

Clinical Genitourinary Cancer

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

36

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

Hodi, F. Stephen, O'Day, Steven J., McDermott, David F., Weber, Robert W., Sosman, Jeffrey A., Haanen, John B., Gonzalez, Rene, Robert, Caroline, Schadendorf, Dirk, Hassel, Jessica C., Akerley, Wallac

Journal:

Boston Medical and Surgical Journal

Year:

2010

Language:

english

File:

PDF, 439 KB

english, 2010

37

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

Sosman, Jeffrey A., Kim, Kevin B., Schuchter, Lynn, Gonzalez, Rene, Pavlick, Anna C., Weber, Jeffrey S., McArthur, Grant A., Hutson, Thomas E., Moschos, Stergios J., Flaherty, Keith T., Hersey, Peter,

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 561 KB

english, 2012

38

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

Flaherty, Keith T., Infante, Jeffery R., Daud, Adil, Gonzalez, Rene, Kefford, Richard F., Sosman, Jeffrey, Hamid, Omid, Schuchter, Lynn, Cebon, Jonathan, Ibrahim, Nageatte, Kudchadkar, Ragini, Burris,

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 528 KB

english, 2012

39

A phase I study of subcutaneously administered aflibercept (VEGF trap) in a new formulation in patients with advanced solid tumors

Andrea Wang-Gillam, William P. Tew, Mace L. Rothenberg, Jakob Dupont, Wendy Cooper, Lars Sternas, Giliane Buzenet, Jeffrey A. Sosman, David R. Spriggs, Albert Craig Lockhart

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 127 KB

english, 2012

40

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

Flaherty, Keith T., Puzanov, Igor, Kim, Kevin B., Ribas, Antoni, McArthur, Grant A., Sosman, Jeffrey A., O'Dwyer, Peter J., Lee, Richard J., Grippo, Joseph F., Nolop, Keith, Chapman, Paul B.

Journal:

Boston Medical and Surgical Journal

Year:

2010

Language:

english

File:

PDF, 830 KB

english, 2010

41

Complications of Targeted Drug Therapies for Solid Malignancies: Manifestations and Mechanisms

Abramson, Richard G., Abramson, Vandana G., Chan, Emily, Horn, Leora, Keedy, Vicki L., Pao, William, Sosman, Jeffrey A.

Journal:

American Journal of Roentgenology

Year:

2013

Language:

english

File:

PDF, 793 KB

english, 2013

42

Update on the Targeted Therapy of Melanoma

Johnson, Douglas B., Sosman, Jeffrey A.

Journal:

Current Treatment Options in Oncology

Year:

2013

Language:

english

File:

PDF, 256 KB

english, 2013

43

Improving outcomes in patients with advanced renal cell carcinoma

Sosman, Jeffrey A

Journal:

Expert Review of Anticancer Therapy

Year:

2008

Language:

english

File:

PDF, 375 KB

english, 2008

44

Impact of MET expression on outcome in BRAF V600E/K advanced melanoma

Jubb, Adrian M, Ribas, Antoni, Sosman, Jeffrey A, McArthur, Grant A, Yan, Yibing, Rost, Sandra, Zhao, Sherry, Koeppen, Hartmut

Journal:

Year:

2013

Language:

english

File:

PDF, 480 KB

english, 2013

45

Melacine®: an allogeneic melanoma tumor cell lysate vaccine

Sosman, Jeffrey A, Sondak, Vernon K

Journal:

Expert Review of Vaccines

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

46

Oral health in oncology: impact of immunotherapy

Jackson, Leanne K., Johnson, Douglas B., Sosman, Jeffrey A., Murphy, Barbara A., Epstein, Joel B.

Journal:

Supportive Care in Cancer

Year:

2015

Language:

english

File:

PDF, 114 KB

english, 2015

47

Phase 1 trial of tivantinib in combination with sorafenib in adult patients with advanced solid tumors

Puzanov, Igor, Sosman, Jeffrey, Santoro, Armando, Saif, Muhammad W., Goff, Laura, Dy, Grace K., Zucali, Paolo, Means-Powell, Julie A., Ma, Wen Wee, Simonelli, Matteo, Martell, Robert, Chai, Feng, Lama

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 439 KB

english, 2015

48

Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma

Hudes, Gary, Carducci, Michael, Tomczak, Piotr, Dutcher, Janice, Figlin, Robert, Kapoor, Anil, Staroslawska, Elzbieta, Sosman, Jeffrey, McDermott, David, Bodrogi, István, Kovacevic, Zoran, Lesovoy, Vl

Journal:

Boston Medical and Surgical Journal

Year:

2007

Language:

english

File:

PDF, 252 KB

english, 2007

49

Trametinib in the treatment of melanoma

Thota, Ramya, Johnson, Douglas B, Sosman, Jeffrey A

Journal:

Expert Opinion on Biological Therapy

Year:

2015

Language:

english

File:

PDF, 300 KB

english, 2015

50

Effect of Selumetinib vs Chemotherapy on Progression-Free Survival in Uveal Melanoma

Carvajal, Richard D., Sosman, Jeffrey A., Quevedo, Jorge Fernando, Milhem, Mohammed M., Joshua, Anthony M., Kudchadkar, Ragini R., Linette, Gerald P., Gajewski, Thomas F., Lutzky, Jose, Lawson, David

Journal:

JAMA The Journal of the American Medical Association

Year:

2014

Language:

english

File:

PDF, 357 KB

english, 2014