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1

Interactions of MAP/microtubule affinity regulating kinases with the adaptor complex AP-2 of clathrin-coated vesicles

Gerold Schmitt-Ulms, Dorthe Matenia, Gerard Drewes, Eva-Maria Mandelkow

Journal:

Year:

2009

Language:

english

File:

PDF, 470 KB

english, 2009

2

Interactome and interface protocol (2IP): A novel strategy for high sensitivity topology mapping of protein complexes

Rasanjala Weerasekera, Yi-Min She, Kelly A. Markham, Yu Bai, Natacha Opalka, Stephen Orlicky, Frank Sicheri, Thomas Kislinger, Gerold Schmitt-Ulms

Journal:

Year:

2007

Language:

english

File:

PDF, 1.00 MB

english, 2007

3

Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins

Kelly Markham, Yu Bai, Gerold Schmitt-Ulms

Journal:

Analytical and Bioanalytical Chemistry

Year:

2007

Language:

english

File:

PDF, 325 KB

english, 2007

4

Wild-type Shadoo proteins convert to amyloid-like forms under native conditions

Nathalie Daude, Vivian Ng, Joel C. Watts, Sacha Genovesi, John Paul Glaves, Serene Wohlgemuth, Gerold Schmitt-Ulms, Howard Young, JoAnne McLaurin, Paul E. Fraser, David Westaway

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

5

10.1038/35089090

Peretz, David, Williamson, R. Anthony, Kaneko, Kiotoshi, Vergara, Julie, Leclerc, Estelle, Schmitt-Ulms, Gerold, Mehlhorn, Ingrid R., Legname, Giuseppe, Wormald, Mark R., Rudd, Pauline M., Dwek, Raymo

Journal:

Year:

2001

Language:

english

File:

PDF, 291 KB

english, 2001

6

Alzheimer's disease: Selectively tuning γ-secretase

St George-Hyslop, Peter, Schmitt-Ulms, Gerold

Journal:

Year:

2010

Language:

english

File:

PDF, 179 KB

english, 2010

7

TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity

Chen, Fusheng, Hasegawa, Hiroshi, Schmitt-Ulms, Gerold, Kawarai, Toshitaka, Bohm, Christopher, Katayama, Taiichi, Gu, Yongjun, Sanjo, Nobuo, Glista, Michael, Rogaeva, Ekaterina

Journal:

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

8

Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues

Schmitt-Ulms, Gerold, Hansen, Kirk, Liu, Jialing, Cowdrey, Cynthia, Yang, Jian, DeArmond, Stephen J, Cohen, Fred E, Prusiner, Stanley B, Baldwin, Michael A

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 886 KB

english, 2004

9

Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

Gerold Schmitt-Ulms, Giuseppe Legname, Michael A Baldwin, Haydn L Ball, Nicole Bradon, Patrick J Bosque, Kathryn L Crossin, Gerald M Edelman, Stephen J DeArmond, Fred E Cohen, Stanley B Prusiner

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 493 KB

english, 2001

10

Family reunion – The ZIP/prion gene family

Sepehr Ehsani, Hairu Huo, Ashkan Salehzadeh, Cosmin L. Pocanschi, Joel C. Watts, Holger Wille, David Westaway, Ekaterina Rogaeva, Peter H. St. George-Hyslop, Gerold Schmitt-Ulms

Journal:

Progress in Neurobiology

Year:

2011

Language:

english

File:

PDF, 584 KB

english, 2011

11

S2-03-04 Assembly of the gamma-secretase complex

Peter St George-Hyslop, Fusheng Chen, YongJun Gu, Hiroshi Hasegawa, Agnes Petit, Anurag Tandon, Peter Mastrangelo, Taiichi Katayama, Paul Matthews, Stephen Schmidt, David Westaway, Gerold Schmitt-Ulms

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

12

513 Phosphorylation of tau by GSK3 and effects on microtubule dynamics

R. Godemann, G. Schmitt-Ulms, S. Illenberger, B. Trinczek, J. Biernat, E.-M. Mandelkow

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 153 KB

english, 1996

13

Alzheimer Disease: Advances in Pathogenesis, Diagnosis, and Therapy

Pasic, M. D., Diamandis, E. P., McLaurin, J., Holtzman, D. M., Schmitt-Ulms, G., Quirion, R.

Journal:

Clinical Chemistry

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

14

O1-02-01: A novel presenilin complex component which modulates gamma- but not epsilon-secretase activity

Paul Fraser, Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt-Ulms, Toshitaka Kawarai, Christopher Bohm, Taiichi Katayama, Yongju Gu, Nobuo Sanjo, Michael Glista, Ekaterina Rogaeva, Yosuke Wakutani, Rap

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

15

Vigilin interacts with signal peptide peptidase

Stephen Hsueh-Jeng Lu, Amy Hye Won Jeon, Gerold Schmitt-Ulms, Seema Qamar, Roger Dodd, Beth McDonald, Yi Li, William Meadows, Katie Cox, Christopher Bohm, Fusheng Chen, Paul Fraser, Peter St George-Hy

Journal:

Proteome Science

Year:

2012

Language:

english

File:

PDF, 1006 KB

english, 2012

16

A Proteome Resource of Ovarian Cancer Ascites: Integrated Proteomic and Bioinformatic Analyses To Identify Putative Biomarkers

Gortzak-Uzan, Limor, Ignatchenko, Alex, Evangelou, Andreas I., Agochiya, Mahima, Brown, Kevin A., St.Onge, Peter, Kireeva, Inga, Schmitt-Ulms, Gerold, Brown, Theodore J., Murphy, Joan, Rosen, Barry, S

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 1.61 MB

english, 2008

17

Peptide Separations by On-Line MudPIT Compared to Isoelectric Focusing in an Off-Gel Format: Application to a Membrane-Enriched Fraction from C2C12 Mouse Skeletal Muscle Cells

Elschenbroich, Sarah, Ignatchenko, Vladimir, Sharma, Parveen, Schmitt-Ulms, Gerold, Gramolini, Anthony O., Kislinger, Thomas

Journal:

Journal of Proteome Research

Year:

2009

Language:

english

File:

PDF, 1.89 MB

english, 2009

18

P3-419

Chen, Fusheng, Schmitt-Ulms, Gerold, Hasegawa, Hiroshi, Fraser, Paul

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

19

P4-149

Watts, Joel C., Drisaldi, Bettina, Strome, Bob, Yang, Jing, Fraser, Paul E., Mount, Howard T.J., Schmitt-Ulms, Gerold, Westaway, David

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 54 KB

english, 2006

20

P3-392

Hasegawa, Hiroshi, Chen, Fusheng, Schmitt-Ulms, Gerold, Kawarai, Toshitaka, Bohm, Christopher, Katayama, Taiichi, Gu, Yong-Jun, Fraser, Paul E., St. George-Hyslop, Peter

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 51 KB

english, 2006

21

Interactome analyses of mature gamma-secretase complexes reveals distinct molecular environments of presenilin paralogs and preferential binding of signal peptide peptidase to PS2

Boehm, Christopher, Won Jeon, Amy Hye, Chen, Fusheng, Fraser, Paul, Mount, Howard, St. George-Hyslop, Peter, Schmitt-Ulms, Gerold

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 50 KB

english, 2013

22

Descent of the Prion Protein Gene Family from the Extracellular Domain of an Ancestral Zip Metal Ion Transporter

Wille, Holger, Ehsani, Sepehr, Watts, Joel C., Westaway, David, Schmitt-Ulms, Gerold

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 76 KB

english, 2010

23

P4-150

Ng, Vivian W.M., Watts, Joel C., Schmitt-Ulms, Gerold, Westaway, David

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

24

Method for the Affinity Purification of Covalently Linked Peptides Following Cyanogen Bromide Cleavage of Proteins

Shi, Tujin, Weerasekera, Rasanjala, Yan, Chen, Reginold, William, Ball, Haydn, Kislinger, Thomas, Schmitt-Ulms, Gerold

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 2.97 MB

english, 2009

25

Endoproteolytic processing of the mammalian prion glycoprotein family

Mays, Charles E., Coomaraswamy, Janaky, Watts, Joel C., Yang, Jing, Ko, Kerry W.S., Strome, Bob, Mercer, Robert C.C., Wohlgemuth, Serene L., Schmitt-Ulms, Gerold, Westaway, David

Journal:

Year:

2014

Language:

english

File:

PDF, 552 KB

english, 2014

26

The Prion Protein Modulates A-type K+ Currents Mediated by Kv4.2 Complexes through Dipeptidyl Aminopeptidase-like Protein 6

Mercer, R. C. C., Ma, L., Watts, J. C., Strome, R., Wohlgemuth, S., Yang, J., Cashman, N. R., Coulthart, M. B., Schmitt-Ulms, G., Jhamandas, J. H., Westaway, D.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 2.93 MB

english, 2013

27

Crosslinking Strategies for the Study of Membrane Protein Complexes and Protein Interaction Interfaces

Weerasekera, Rasanjala, Schmitt-Ulms, Gerold

Journal:

Biotechnology and Genetic Engineering Reviews

Year:

2006

Language:

english

File:

PDF, 1.55 MB

english, 2006

28

The Presenilin Proteins Are Components of Multiple Membrane-bound Complexes That Have Different Biological Activities

Gu, Y., Sanjo, N., Chen, F., Hasegawa, H., Petit, A., Ruan, X., Li, W., Shier, C., Kawarai, T., Schmitt-Ulms, G., Westaway, D., St George-Hyslop, P., Fraser, P. E.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.15 MB

english, 2004

29

TMP21 Transmembrane Domain Regulates -Secretase Cleavage

Pardossi-Piquard, R., Bohm, C., Chen, F., Kanemoto, S., Checler, F., Schmitt-Ulms, G., St. George-Hyslop, P., Fraser, P. E.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.70 MB

english, 2009

30

Interactome Analyses of Mature -Secretase Complexes Reveal Distinct Molecular Environments of Presenilin (PS) Paralogs and Preferential Binding of Signal Peptide Peptidase to PS2

Jeon, A. H. W., Bohm, C., Chen, F., Huo, H., Ruan, X., Ren, C. H., Ho, K., Qamar, S., Mathews, P. M., Fraser, P. E., Mount, H. T. J., St George-Hyslop, P., Schmitt-Ulms, G.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 2.16 MB

english, 2013

31

The in Vivo Brain Interactome of the Amyloid Precursor Protein

Bai, Y., Markham, K., Chen, F., Weerasekera, R., Watts, J., Horne, P., Wakutani, Y., Bagshaw, R., Mathews, P. M., Fraser, P. E., Westaway, D., St. George-Hyslop, P., Schmitt-Ulms, G.

Journal:

Molecular & Cellular Proteomics

Year:

2007

Language:

english

File:

PDF, 849 KB

english, 2007

32

Both the Sequence and Length of the C Terminus of PEN-2 Are Critical for Intermolecular Interactions and Function of Presenilin Complexes

Hasegawa, H., Sanjo, N., Chen, F., Gu, Y.-J., Shier, C., Petit, A., Kawarai, T., Katayama, T., Schmidt, S. D., Mathews, P. M., Schmitt-Ulms, G., Fraser, P. E., George-Hyslop, P. S.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.07 MB

english, 2004

33

Structural biology of presenilin 1 complexes

Li, Yi, Bohm, Christopher, Dodd, Roger, Chen, Fusheng, Qamar, Seema, Schmitt-Ulms, Gerold, Fraser, Paul E, St George-Hyslop, Peter H

Journal:

Molecular Neurodegeneration

Year:

2014

Language:

english

File:

PDF, 971 KB

english, 2014

34

APH1 Polar Transmembrane Residues Regulate the Assembly and Activity of Presenilin Complexes

Pardossi-Piquard, R., Yang, S.-P., Kanemoto, S., Gu, Y., Chen, F., Bohm, C., Sevalle, J., Li, T., Wong, P. C., Checler, F., Schmitt-Ulms, G., St. George-Hyslop, P., Fraser, P. E.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.26 MB

english, 2009

35

Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones

Watts, Joel C., Huo, Hairu, Bai, Yu, Ehsani, Sepehr, Won, Amy Hye, Shi, Tujin, Daude, Nathalie, Lau, Agnes, Young, Rebecca, Xu, Lei, Carlson, George A., Williams, David, Westaway, David, Schmitt-Ulms,

Journal:

Year:

2009

Language:

english

File:

PDF, 585 KB

english, 2009

36

Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

Bohm, C., Chen, F., Sevalle, J., Qamar, S., Dodd, R., Li, Y., Schmitt-Ulms, G., Fraser, P.E., St George-Hyslop, P.H.

Journal:

Molecular and Cellular Neuroscience

Year:

2015

Language:

english

File:

PDF, 768 KB

english, 2015

37

The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome

Gunawardana, C. Geeth, Mehrabian, Mohadeseh, Wang, Xinzhu, Mueller, Iris, Lubambo, Isabela B., Jonkman, James E. N., Wang, Hansen, Schmitt-Ulms, Gerold

Journal:

Molecular & Cellular Proteomics

Year:

2015

Language:

english

File:

PDF, 1011 KB

english, 2015

38

The ZIP-prion connection

Ehsani, Sepehr, Mehrabian, Mohadeseh, Pocanschi, Cosmin L., Schmitt-Ulms, Gerold

Journal:

Year:

2012

Language:

english

File:

PDF, 991 KB

english, 2012

39

Childhood Onset in Familial Prion Disease With a Novel Mutation in the PRNP Gene

Rogaeva, Ekaterina, Zadikoff, Cindy, Ponesse, Jonathan, Schmitt-Ulms, Gerold, Kawarai, Toshitaka, Sato, Christine, Salehi-Rad, Shabnam, St. George-Hyslop, Peter, Lang, Anthony E.

Journal:

Archives of Neurology

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

40

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration

Taylor, K. M., Muraina, I. A., Brethour, D., Schmitt-Ulms, G., Nimmanon, T., Ziliotto, S., Kille, P., Hogstrand, C.

Journal:

Biochemical Journal

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

41

CRISPR-Cas9 System: Opportunities and Concerns

Vasiliou, S. K., Diamandis, E. P., Church, G. M., Greely, H. T., Baylis, F., Thompson, C., Schmitt-Ulms, G.

Journal:

Clinical Chemistry

Year:

2016

Language:

english

File:

PDF, 450 KB

english, 2016

42

Does BDNF Val66Met contribute to preclinical Alzheimer’s disease?

Rogaeva, Ekaterina, Schmitt-Ulms, Gerold

Journal:

Year:

2016

Language:

english

File:

PDF, 302 KB

english, 2016

43

NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?

Mehrabian, M., Hildebrandt, H., Schmitt-Ulms, G.

Journal:

Year:

2016

Language:

english

File:

PDF, 670 KB

english, 2016

44

BINDING WITH THE WRONG PARTNERS: A CRISPR/CAS9-EDITED INDUCIBLE HUMAN CELL SYSTEM DESIGNED TO REVEAL THE CHRONOLOGY OF EVENTS LEADING TO PROTEOTOXIC STRESS IN TAUOPATHIES

Wang, Xinzhu, Lubambo, Isabela, Mueller, Iris, Dukart, Ramona, Schmitt-Ulms, Gerold

Journal:

Alzheimer's & Dementia

Year:

2016

Language:

english

File:

PDF, 66 KB

english, 2016

45

Proteome-wide identification of mycobacterial pupylation targets

Poulsen, Christian, Akhter, Yusuf, Jeon, Amy Hye-Won, Schmitt-Ulms, Gerold, Meyer, Helmut E, Stefanski, Anja, Stühler, Kai, Wilmanns, Matthias, Song, Young-Hwa

Journal:

Molecular Systems Biology

Year:

2010

Language:

english

File:

PDF, 802 KB

english, 2010

46

Somatostatin in Alzheimer'S disease: A new Role for an Old Player

Solarski, Michael, Wang, Hansen, Wille, Holger, Schmitt-Ulms, Gerold

Journal:

Year:

2017

Language:

english

File:

PDF, 1016 KB

english, 2017

47

Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

Ruiz-Riquelme, Alejandro, Lau, Heather H. C., Stuart, Erica, Goczi, Adrienn N., Wang, Zhilan, Schmitt-Ulms, Gerold, Watts, Joel C.

Journal:

Acta Neuropathologica Communications

Year:

2018

Language:

english

File:

PDF, 6.64 MB

english, 2018

48

The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling

Ghodrati, Farinaz, Mehrabian, Mohadeseh, Williams, Declan, Halgas, Ondrej, Bourkas, Matthew E. C., Watts, Joel C., Pai, Emil F., Schmitt-Ulms, Gerold

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.68 MB

english, 2018

49

Evidence for Retrogene Origins of the Prion Gene Family

Ehsani, Sepehr, Tao, Renzhu, Pocanschi, Cosmin L., Ren, Hezhen, Harrison, Paul M., Schmitt-Ulms, Gerold, Mouillet-Richard, Sophie

Journal:

Year:

2011

Language:

english

File:

PDF, 4.90 MB

english, 2011

50

PrionHome: A Database of Prions and Other Sequences Relevant to Prion Phenomena

Harbi, Djamel, Parthiban, Marimuthu, Gendoo, Deena M. A., Ehsani, Sepehr, Kumar, Manish, Schmitt-Ulms, Gerold, Sowdhamini, Ramanathan, Harrison, Paul M., Mouillet-Richard, Sophie

Journal:

Year:

2012

Language:

english

File:

PDF, 573 KB

english, 2012

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