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1

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock

Sparkes, Amanda, De Baetselier, Patrick, Brys, Lea, Cabrito, Inês, Sterckx, Yann G.-J., Schoonooghe, Steve, Muyldermans, Serge, Raes, Geert, Bucala, Richard, Vanlandschoot, Peter, Van Ginderachter, Jo

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

2

Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer

Steve Schoonooghe, Damya Laoui, Jo A. Van Ginderachter, Nick Devoogdt, Tony Lahoutte, Patrick De Baetselier, Geert Raes

Journal:

Year:

2012

Language:

english

File:

PDF, 613 KB

english, 2012

3

Fab Chains As an Efficient Heterodimerization Scaffold for the Production of Recombinant Bispecific and Trispecific Antibody Derivatives

Schoonjans, R., Willems, A., Schoonooghe, S., Fiers, W., Grooten, J., Mertens, N.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 1.03 MB

english, 2000

4

A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain

Reinhilde Schoonjans, An Willems, Steve Schoonooghe, Jannick Leœn, Johan Grooten, Nico Mertens

Journal:

Biomolecular Engineering

Year:

2001

Language:

english

File:

PDF, 231 KB

english, 2001

5

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies inPichia pastoris

Steve Schoonooghe, Vladimir Kaigorodov, Monika Zawisza, Caroline Dumolyn, Jurgen Haustraete, Johan Grooten, Nico Mertens

Journal:

BMC Biotechnology

Year:

2009

Language:

english

File:

PDF, 1.89 MB

english, 2009

6

CD3

An Willems, Steve Schoonooghe, Dominique Eeckhout, Geert De Jaeger, Johan Grooten, Nico Mertens

Journal:

Cancer Immunology, Immunotherapy

Year:

2005

Language:

english

File:

PDF, 638 KB

english, 2005

7

Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives

An Willems, Jannick Leoen, Steve Schoonooghe, Johan Grooten, Nico Mertens

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 1.30 MB

english, 2003

8

Malignant Large Cell Calcifying Sertoli Cell Tumor of the Testis

H. De Raeve, P. Schoonooghe, R. Wibowo, E. Van Marck, A. Goossens

Journal:

Pathology - Research and Practice

Year:

2003

Language:

english

File:

PDF, 241 KB

english, 2003

9

Generation and characterization of a functional Nanobody against the vascular endothelial growth factor receptor-2; angiogenesis cell receptor

Mahdi Behdani, Sirous Zeinali, Hossein Khanahmad, Morteza Karimipour, Nader Asadzadeh, Keyhan Azadmanesh, Alireza Khabiri, Steve Schoonooghe, Mahdi Habibi Anbouhi, Gholamreza Hassanzadeh-Ghassabeh, Se

Journal:

Molecular Immunology

Year:

2012

Language:

english

File:

PDF, 812 KB

english, 2012

10

Biodistribution and planar gamma camera imaging of 123I- and 131I-labeled F(ab′)2 and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor

Ingrid J.G. Burvenich, Steve Schoonooghe, Peter Blanckaert, Klaus Bacher, Liesbet Vervoort, Elisabeth Coene, Nico Mertens, Filip De Vos, Guido Slegers

Journal:

Nuclear Medicine and Biology

Year:

2007

Language:

english

File:

PDF, 555 KB

english, 2007

11

SPECT Imaging of Joint Inflammation with Nanobodies Targeting the Macrophage Mannose Receptor in a Mouse Model for Rheumatoid Arthritis

Put, S., Schoonooghe, S., Devoogdt, N., Schurgers, E., Avau, A., Mitera, T., D'Huyvetter, M., De Baetselier, P., Raes, G., Lahoutte, T., Matthys, P.

Journal:

Journal of Nuclear Medicine

Year:

2013

Language:

english

File:

PDF, 920 KB

english, 2013

12

Generation andin vivocharacterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives

Caroline Dumolyn, Steve Schoonooghe, Lieselotte Moerman, Sara Neyt…

Journal:

EJNMMI Research

Year:

2013

Language:

english

File:

PDF, 571 KB

english, 2013

13

Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth

Behdani, Mahdi, Zeinali, Sirous, Karimipour, Morteza, Khanahmad, Hossein, Schoonooghe, Steve, Aslemarz, Azam, Seyed, Negar, Moazami-Godarzi, Reza, Baniahmad, Farzad, Habibi-Anbouhi, Mahdi, Hassanzadeh

Journal:

New Biotechnology

Year:

2013

Language:

english

File:

PDF, 511 KB

english, 2013

14

New Strategies in Polypeptide and Antibody Synthesis: An Overview

Mertens, Nico, Devos, Filip, Leoen, Jannick, Van Deynse, Els, Willems, An, Schoonooghe, Steve, Burvenich, Ingrid, De Koker, Stefaan, Vlieghe, Dominique, Grooten, Johan, Kelly, Andrew, Van de Wiele, Ch

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2004

Language:

english

File:

PDF, 515 KB

english, 2004

15

Molecular Imaging with Macrophage CRIg-Targeting Nanobodies for Early and Preclinical Diagnosis in a Mouse Model of Rheumatoid Arthritis

Zheng, F., Put, S., Bouwens, L., Lahoutte, T., Matthys, P., Muyldermans, S., De Baetselier, P., Devoogdt, N., Raes, G., Schoonooghe, S.

Journal:

Journal of Nuclear Medicine

Year:

2014

Language:

english

File:

PDF, 1019 KB

english, 2014

16

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

Zheng, Fang, Devoogdt, Nick, Sparkes, Amanda, Morias, Yannick, Abels, Chloé, Stijlemans, Benoit, Lahoutte, Tony, Muyldermans, Serge, De Baetselier, Patrick, Schoonooghe, Steve, Beschin, Alain, Raes, G

Journal:

Year:

2015

Language:

english

File:

PDF, 3.65 MB

english, 2015

17

Monoclonal antibody 14C5 targets integrin v 5

Burvenich, I., Schoonooghe, S., Vervoort, L., Dumolyn, C., Coene, E., Vanwalleghem, L., Van Huysse, J., Praet, M., Cuvelier, C., Mertens, N., De Vos, F., Slegers, G.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 419 KB

english, 2008

18

PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1

Schoonooghe, S., Burvenich, I., Vervoort, L., De Vos, F., Mertens, N., Grooten, J.

Journal:

Protein Engineering Design and Selection

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

19

Surgery for non-small cell lung cancer with unsuspected metastasis to ipsilateral mediastinal or subcarinal nodes (N2 disease)

DELEYN, P, SCHOONOOGHE, P, DENEFFE, G, VANRAEMDONCK, D, COOSEMANS, W, LERUT, T, VANSTEENKISTE, J

Journal:

European Journal of Cardio-Thoracic Surgery

Year:

1996

Language:

english

File:

PDF, 627 KB

english, 1996

20

Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages

Movahedi, K., Schoonooghe, S., Laoui, D., Houbracken, I., Waelput, W., Breckpot, K., Bouwens, L., Lahoutte, T., De Baetselier, P., Raes, G., Devoogdt, N., Van Ginderachter, J. A.

Journal:

Cancer Research

Year:

2012

Language:

english

File:

PDF, 2.65 MB

english, 2012

21

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

Blykers, A., Schoonooghe, S., Xavier, C., D'hoe, K., Laoui, D., D'Huyvetter, M., Vaneycken, I., Cleeren, F., Bormans, G., Heemskerk, J., Raes, G., De Baetselier, P., Lahoutte, T., Devoogdt, N., Van Gi

Journal:

Journal of Nuclear Medicine

Year:

2015

Language:

english

File:

PDF, 968 KB

english, 2015

22

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Scott, Charlotte L., Zheng, Fang, De Baetselier, Patrick, Martens, Liesbet, Saeys, Yvan, De Prijck, Sofie, Lippens, Saskia, Abels, Chloé, Schoonooghe, Steve, Raes, Geert, Devoogdt, Nick, Lambrecht, Ba

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.51 MB

english, 2016

23

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis

Zheng, Fang, Sparkes, Amanda, De Baetselier, Patrick, Schoonooghe, Steve, Stijlemans, Benoit, Muyldermans, Serge, Flamand, Véronique, Van Ginderachter, Jo A, Devoogdt, Nick, Raes, Geert, Beschin, Alai

Journal:

Molecular Imaging and Biology

Year:

2017

Language:

english

File:

PDF, 4.20 MB

english, 2017

24

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

Zheng, Fang, Perlman, Harris, Matthys, Patrick, Wen, Yurong, Lahoutte, Tony, Muyldermans, Serge, Lu, Shemin, De Baetselier, Patrick, Schoonooghe, Steve, Devoogdt, Nick, Raes, Geert

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

25

Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity

Wen, Yurong, Ouyang, Zhenlin, Schoonooghe, Steve, Luo, Siyu, De Baetselier, Patrick, Lu, Wuyuan, Muyldermans, Serge, Raes, Geert, Zheng, Fang

Journal:

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

26

Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

Van den Hoecke, Silvie, Ehrhardt, Katrin, Kolpe, Annasaheb, El Bakkouri, Karim, Deng, Lei, Grootaert, Hendrik, Schoonooghe, Steve, Smet, Anouk, Bentahir, Mostafa, Roose, Kenny, Schotsaert, Michael, Sc

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

27

SAT0075 The use of macrophage mannose receptor-targeting nanobodies and spect imaging to study joint inflammation in mice with collagen-induced arthritis

Put, S., Schoonooghe, S., Devoogdt, N., Schurgers, E., Avau, A., Mitera, T., De Baetselier, P., Raes, G., Lahoutte, T., Matthys, P.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

28

An unexpected Campylobacter fetus infection

Nulens, Eric, Decoster, Eva-Line, Schoonooghe, Marie-Christine, Muyldermans, Astrid

Journal:

Year:

2018

Language:

english

File:

PDF, 730 KB

english, 2018

29

Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages

De Vlaeminck, Yannick, Lecocq, Quentin, Giron, Philippe, Heirman, Carlo, Geeraerts, Xenia, Bolli, Evangelia, Movahedi, Kiavash, Massa, Sam, Schoonooghe, Steve, Thielemans, Kris, Goyvaerts, Cleo, Van G

Journal:

Journal of Controlled Release

Year:

2019

Language:

english

File:

PDF, 1.72 MB

english, 2019

30

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent

Broos,, Lecocq,, Xavier,, Bridoux,, Nguyen,, Corthals,, Schoonooghe,, Lion,, Raes,, Keyaerts,, Devoogdt,, Breckpot,

Journal:

Year:

2019

Language:

english

File:

PDF, 4.80 MB

english, 2019

31

NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis

Zheng, Fang, Luo, Siyu, Ouyang, Zhenlin, Zhou, Jinhong, Mo, Huanye, Schoonooghe, Steve, Muyldermans, Serge, De Baetselier, Patrick, Raes, Geert, Wen, Yurong

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 9.93 MB

english, 2019

32

NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis

Zheng, Fang, Luo, Siyu, Ouyang, Zhenlin, Zhou, Jinhong, Mo, Huanye, Schoonooghe, Steve, Muyldermans, Serge, De Baetselier, Patrick, Raes, Geert, Wen, Yurong

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 9.93 MB

2019

33

Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development

De Vlaeminck, Yannick, Bonelli, Stefano, Awad, Robin Maximilian, Dewilde, Maarten, Rizzolio, Sabrina, Lecocq, Quentin, Bolli, Evangelia, Santos, Ana Rita, Laoui, Damya, Schoonooghe, Steve, Tamagnone,

Journal:

Year:

2020

File:

PDF, 4.91 MB

2020

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