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51

The effect of ajmalicine spiking and resin addition timing on the production of indole alkaloids from Catharanthus roseus cell cultures

Carolyn W. T. Lee-Parsons, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 163 KB

english, 2002

52

Hepatitis B surface antigen (HBsAg) expression in plant cell culture: Kinetics of antigen accumulation in batch culture and its intracellular form

Mark L. Smith, Hugh S. Mason, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 425 KB

english, 2002

53

Effect of silkworm hemolymph on N-linked glycosylation in two Trichoplusia ni insect cell lines

Christoph E. Joosten, Tai Hyun Park, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

54

A self-priming microfluidic diaphragm pump capable of recirculation fabricated by combining soft lithography and traditional machining

Aaron Sin, Christopher F. Reardon, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2004

Language:

english

File:

PDF, 383 KB

english, 2004

55

Robust control of initiation of prokaryotic chromosome replication: Essential considerations for a minimal cell

Samuel T. Browning, Mariajosé Castellanos, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2004

Language:

english

File:

PDF, 666 KB

english, 2004

56

Antibody-based surface plasmon resonance detection of intact viral pathogen

Hyoungwon Baac, József P. Hajós, Jennifer Lee, Donghyun Kim, Sung June Kim, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

57

Effect of the plant peptide regulator, phytosulfokine-α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim, Donna M. Gibson, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 226 KB

english, 2006

58

A genomically/chemically complete module for synthesis of lipid membrane in a minimal cell

Mariajose Castellanos, Keiichiro Kushiro, Samuel K. Lai, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 281 KB

english, 2007

59

Influence of culture medium supplementation of tobacco NT1 cell suspension cultures on the N-glycosylation of human secreted alkaline phosphatase

Alejandro Becerra-Arteaga, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 169 KB

english, 2007

60

Molecular engineering of epoxide hydrolase and its application to asymmetric and enantioconvergent hydrolysis

Eun Yeol Lee, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 198 KB

english, 2007

61

An actively mixed mini-bioreactor for protein production from suspended animal cells

Jinpian Diao, Lincoln Young, Peng Zhou, Michael Louis Shuler

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 266 KB

english, 2008

62

Development of a stable dual cell-line GFP expression system to study estrogenic endocrine disruptors

Hui Xu, W. Lee Kraus, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 393 KB

english, 2008

63

Cell cycle progression in Escherichia coli B/r affects transcription of certain genes: Implications for synthetic genome design

Patricia L. Echtenkamp, David B. Wilson, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 188 KB

english, 2009

64

A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers

Daniel A. Tatosian, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 638 KB

english, 2009

65

Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices

Jong Hwan Sung, Jong-ryul Choi, Donghyun Kim, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 322 KB

english, 2009

66

Complex responses to culture conditions in Pseudomonas syringae pv. tomato DC3000 continuous cultures: The role of iron in cell growth and virulence factor induction

Beum Jun Kim, David J. Schneider, Samuel W. Cartinhour, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

67

Batch, fed-batch, and microcarrier cultures with CHO cell lines in a pressure-cycle driven miniaturized bioreactor

Beum Jun Kim, Ti Zhao, Lincoln Young, Peng Zhou, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

2012

Language:

english

File:

PDF, 522 KB

english, 2012

68

Multiple steady-state phenomena within enzyme reactors: The enzyme reaction with two substrates

Ian A. Webster, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1981

Language:

english

File:

PDF, 643 KB

english, 1981

69

Bioreactor considerations for secondary metabolite production from plant cell tissue culture: Indole alkaloids from Catharanthus roseus

Gregory F. Payne, Nadine N. Payne, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1988

Language:

english

File:

PDF, 790 KB

english, 1988

70

Release of periplasmic enzymes and other physiological effects of β-lactamase overproduction in Escherichia coli

George Georgiou, Michael L. Shuler, David B. Wilson

Journal:

Biotechnology and Bioengineering

Year:

1988

Language:

english

File:

PDF, 1.48 MB

english, 1988

71

Kinetic analysis of the effects of plasmid multimerization on segregational instability of CoIE1 type plasmids in Escherichia coli B/r

Byung Gee Kim, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 1.08 MB

english, 1991

72

Continuous, high level production and excretion of a plasmid-encoded protein by Escherichia coli in a two-stage chemostat

Jeffrey Fu, David B. Wilson, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1993

Language:

english

File:

PDF, 893 KB

english, 1993

73

Use of a simple mathematical model to predict the behavior of Escherichia coli overproducing β-lactamase within continuous single- and two-stage reactor systems

A. Paul Togna, Jeffrey Fu, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1993

Language:

english

File:

PDF, 1.15 MB

english, 1993

74

Interactions of microbial biofilms with toxic trace metals: 1. Observation and modeling of cell growth, attachment, and production of extracellular polymer

Ke Ming Hsieh, George A. Murgel, Leonard W. Lion, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1994

Language:

english

File:

PDF, 1.16 MB

english, 1994

75

Interactions of microbial biofilms with toxic trace metals: 2. Prediction and verification of an integrated computer model of lead (II) distribution in the presence of microbial activity

Ke Ming Hsieh, George A. Murgel, Leonard W. Lion, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1994

Language:

english

File:

PDF, 710 KB

english, 1994

76

A model of the binding, entry, uncoating, and RNA synthesis of Semliki Forest virus in baby hamster kidney (BHK-21) cells

Kennie U. Dee, Daniel A. Hammer, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1995

Language:

english

File:

PDF, 1.06 MB

english, 1995

77

Taxol production in bioreactors: Kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata

Venkatesh Srinivasan, Luis Pestchanker, Susan Moser, Thomas J. Hirasuna, Ronald A. Taticek, Michael L. Shuler

Journal:

Biotechnology and Bioengineering

Year:

1995

Language:

english

File:

PDF, 970 KB

english, 1995

78

Quantification of chemical–polymer surface interactions in microfluidic cell culture devices

Hui Xu, Michael L. Shuler

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 336 KB

english, 2009

79

The effect of astrocytes on the induction of barrier properties in aortic endothelial cells

Gilda Shayan, Michael L. Shuler, Kelvin H. Lee

Journal:

Biotechnology Progress

Year:

2011

Language:

english

File:

PDF, 525 KB

english, 2011

80

Real-time fluorescence detection of multiple microscale cell culture analog devices in situ

Taek-il Oh, Jong Hwan Sung, Daniel A. Tatosian, Michael L. Shuler, Donghyun Kim

Journal:

Cytometry Part A

Year:

2007

Language:

english

File:

PDF, 483 KB

english, 2007

81

A combined pharmacokinetic–pharmacodynamic (PK–PD) model for tumor growth in the rat with UFT administration

Jong Hwan Sung, Anjali Dhiman, Michael L. Shuler

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 295 KB

english, 2009

82

Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor

Luis J. Pestchanker, Susan C. Roberts, Michael L. Shuler

Journal:

Enzyme and Microbial Technology

Year:

1996

Language:

english

File:

PDF, 520 KB

english, 1996

83

Sparge gas composition affects biomass and ajmalicine production from immobilized cell cultures of Catharanthus roseus

Carolyn W.T. Lee-Parsons, Michael L. Shuler

Journal:

Enzyme and Microbial Technology

Year:

2005

Language:

english

File:

PDF, 508 KB

english, 2005

84

Promises, challenges and future directions of μCCAs

Mandy B. Esch, Jong H. Sung, Michael L. Shuler

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

85

Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability

Gretchen J. Mahler, Michael L. Shuler, Raymond P. Glahn

Journal:

The Journal of Nutritional Biochemistry

Year:

2009

Language:

english

File:

PDF, 1.52 MB

english, 2009

86

Sensitivity and control analysis of periodically forced reaction networks using the Green's function method

Evgeni V. Nikolaev, Jordan C. Atlas, Michael L. Shuler

Journal:

Journal of Theoretical Biology

Year:

2007

Language:

english

File:

PDF, 616 KB

english, 2007

87

Predicting threshold concentrations of organic substrates for bacterial growth

Steven K. Schmidt, Martin Alexander, Michael L. Shuler

Journal:

Journal of Theoretical Biology

Year:

1985

Language:

english

File:

PDF, 455 KB

english, 1985

88

Large-scale plant cell culture

Susan C Roberts, Michael L Shuler

Journal:

Current Opinion in Biotechnology

Year:

1997

Language:

english

File:

PDF, 788 KB

english, 1997

89

Taxol production in suspension cultures ofTaxus baccata

Thomas J. Hirasuna, Luis J. Pestchanker, Venkatesh Srinivasan, Michael L. Shuler

Journal:

Plant Cell, Tissue and Organ Culture

Year:

1996

Language:

english

File:

PDF, 633 KB

english, 1996

90

Different shake flask closures alter gas phase composition and ajmalicine production inCatharanthus roseuscell suspensions

Carolyn W. T. Lee, Michael L. Shuler

Journal:

Biotechnology Techniques

Year:

1991

Language:

english

File:

PDF, 320 KB

english, 1991

91

Stimulation of ajmalicine production and excretion fromCatharanthus roseus: effects of adsorption in situ, elicitors and alginate immobilization

Masanori Asada, Michael L. Shuler

Journal:

Applied Microbiology and Biotechnology

Year:

1989

Language:

english

File:

PDF, 668 KB

english, 1989

92

Expression of human epidermal growth factor byEscherichia coliin continuous culture

Eunki Kim, Jeffrey Fu, David B. Wilson, Michael L. Shuler

Journal:

Biotechnology Letters

Year:

1992

Language:

english

File:

PDF, 311 KB

english, 1992

93

Production of extracellular and cell-associated biopolymers byPseudomonas atlantica

Ke Ming Hsieh, Leonard W. Lion, Michael L. Shuler

Journal:

Biotechnology Letters

Year:

1990

Language:

english

File:

PDF, 473 KB

english, 1990

94

Effect of alkaline medium on the production and excretion of B-lactamase byEscherichia coli

George Georgiou, Terry Palumbo, David B. Wilson, Michael L. Shuler

Journal:

Biotechnology Letters

Year:

1988

Language:

english

File:

PDF, 338 KB

english, 1988

95

In situ adsorption for enhanced alkaloid production byCatharanthusroseus

Gregory F. Payne, Nadine N. Payne, Michael L. Shuler, Masanori Asada

Journal:

Biotechnology Letters

Year:

1988

Language:

english

File:

PDF, 351 KB

english, 1988

96

Growth of endothelial cells on microfabricated silicon nitride membranes for anin vitromodel of the blood-brain barrier

Sarina G. Harris, Michael L. Shuler

Journal:

Biotechnology and Bioprocess Engineering

Year:

2003

File:

PDF, 201 KB

2003

97

An uncertain role for Cu(II) in stimulating Mn(II) oxidation byLeptothrix discophoraSS-1

Iman A. El Gheriany, Daniela Bocioaga, Anthony G. Hay, William C. Ghiorse, Michael L. Shuler, Leonard W. Lion

Journal:

Archives of Microbiology

Year:

2011

Language:

english

File:

PDF, 289 KB

english, 2011

98

In vitro microscale systems for systematic drug toxicity study

Jong Hwan Sung, Michael L. Shuler

Journal:

Bioprocess and Biosystems Engineering

Year:

2010

Language:

english

File:

PDF, 502 KB

english, 2010

99

Effects of Glial Cells on Electrode Impedance Recorded from Neural Prosthetic DevicesIn Vitro

John P. Frampton, Matthew R. Hynd, Michael L. Shuler, William Shain

Journal:

Annals of Biomedical Engineering

Year:

2010

Language:

english

File:

PDF, 971 KB

english, 2010

100

Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish,Mugil cephalus

Soo Jung Lee, Hee Sook Kim, Sang Jin Kim, Sunghoon Park, Beum Jun Kim, Michael L. Shuler, Eun Yeol Lee

Journal:

Biotechnology Letters

Year:

2007

Language:

english

File:

PDF, 566 KB

english, 2007