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1

For the record

Lindahl, Maria, Danilova, Tatiana, Palm, Erik, Lindholm, Päivi, Võikar, Vootele, Hakonen, Elina, Ustinov, Jarkko, Andressoo, Jaan-Olle, Harvey, Brandon K., Otonkoski, Timo, Rossi, Jari, Saarma, Mart

Journal:

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

2

Hepatocyte Growth Factor/Scatter Factor Has Insulinotropic Activity in Human Fetal Pancreatic Cells

Otonkoski, T., Beattie, G. M., Rubin, J. S., Lopez, A. D., Baird, A., Hayek, A.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.40 MB

english, 1994

3

Regulation of Proliferation and Differentiation of Human Fetal Pancreatic Islet Cells by Extracellular Matrix, Hepatocyte Growth Factor, and Cell-Cell Contact

Beattie, G. M., Rubin, J. S., Mally, M. I., Otonkoski, T., Hayek, A.

Journal:

Year:

1996

Language:

english

File:

PDF, 1.52 MB

english, 1996

4

Insulin-like growth factor-II and transforming growth factor- in developing human fetal pancreatic islets

Miettinen, P. J., Otonkoski, T., Voutilainen, R.

Journal:

Journal of Endocrinology

Year:

1993

Language:

english

File:

PDF, 22.70 MB

english, 1993

5

Chromosomal alterations in human pancreatic endocrine tumors

Erik Stumpf, Yan Aalto, Anders Höög, Magnus Kjellman, Timo Otonkoski, Sakari Knuutila, Leif C. Andersson

Journal:

Genes, Chromosomes and Cancer

Year:

2000

Language:

english

File:

PDF, 77 KB

english, 2000

6

A syndrome with multiple malformations, mental retardation, and ACTH deficiency

Eero Kajantie, Timo Otonkoski, Sirpa Kivirikko, Mirja Somer

Journal:

American Journal of Medical Genetics Part A

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

7

Mechanisms of beta cell death during restricted and unrestricted enterovirus infection

Suvi Rasilainen, Petri Ylipaasto, Merja Roivainen, Luc Bouwens, Risto Lapatto, Tapani Hovi, Timo Otonkoski

Journal:

Journal of Medical Virology

Year:

2004

Language:

english

File:

PDF, 418 KB

english, 2004

8

Mechanisms of coxsackievirus B5 mediated β-cell death depend on the multiplicity of infection

Suvi Rasilainen, Petri Ylipaasto, Merja Roivainen, Risto Lapatto, Tapani Hovi, Timo Otonkoski

Journal:

Journal of Medical Virology

Year:

2004

Language:

english

File:

PDF, 475 KB

english, 2004

9

Cow Milk Feeding Induces Antibodies to Insulin in Children – A Link Between Cow Milk and Insulin-Dependent Diabetes Mellitus?

Vaarala, Paronen, Otonkoski, Åkerblom

Journal:

Scandinavian Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 214 KB

english, 1998

10

Distinct differentiation characteristics of individual human embryonic stem cell lines

Milla Mikkola, Cia Olsson, Jaan Palgi, Jarkko Ustinov, Tiina Palomaki, Nina Horelli-Kuitunen, Sakari Knuutila, Karolina Lundin, Timo Otonkoski, Timo Tuuri

Journal:

BMC Developmental Biology

Year:

2006

Language:

english

File:

PDF, 2.12 MB

english, 2006

11

ICA69 is expressed equally in the human endocrine and exocrine pancreas

M. I. Mally, V. Cirulli, A. Hayek, T. Otonkoski

Journal:

Year:

1996

Language:

english

File:

PDF, 3.17 MB

english, 1996

12

Transplantation of human fetal pancreas: fresh vs. cultured fetal islets or ICCS

G. M. Beattie, A. D. Lopez, T. Otonkoski, A. Hayek

Journal:

Journal of Molecular Medicine

Year:

1999

Language:

english

File:

PDF, 29 KB

english, 1999

13

Functional impairment and killing of human beta cells by enteroviruses: the capacity is shared by a wide range of serotypes, but the extent is a characteristic of individual virus strains

M. Roivainen, P. Ylipaasto, C. Savolainen, J. Galama, T. Hovi, T. Otonkoski

Journal:

Year:

2002

Language:

english

File:

PDF, 391 KB

english, 2002

14

Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population

F. Reimann, H. Huopio, M. Dabrowski, P. Proks, F. M. Gribble, M. Laakso, T. Otonkoski, F. M. Ashcroft

Journal:

Year:

2004

Language:

english

File:

PDF, 104 KB

english, 2004

15

Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells

P. Ylipaasto, K. Klingel, A. M. Lindberg, T. Otonkoski, R. Kandolf, T. Hovi, M. Roivainen

Journal:

Year:

2004

Language:

english

File:

PDF, 1.03 MB

english, 2004

16

Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets

P. Ylipaasto, B. Kutlu, S. Rasilainen, J. Rasschaert, K. Salmela, H. Teerijoki, O. Korsgren, R. Lahesmaa, T. Hovi, D. L. Eizirik, T. Otonkoski, M. Roivainen

Journal:

Year:

2005

Language:

english

File:

PDF, 550 KB

english, 2005

17

In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells

R. Gao, J. Ustinov, O. Korsgren, T. Otonkoski

Journal:

Year:

2005

Language:

english

File:

PDF, 352 KB

english, 2005

18

Blood vessels of human islets of Langerhans are surrounded by a double basement membrane

I. Virtanen, M. Banerjee, J. Palgi, O. Korsgren, A. Lukinius, L.-E. Thornell, Y. Kikkawa, K. Sekiguchi, M. Hukkanen, Y. T. Konttinen, T. Otonkoski

Journal:

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

19

A simple two-step protocol for the purification of human pancreatic beta cells

M. Banerjee, T. Otonkoski

Journal:

Year:

2009

Language:

english

File:

PDF, 241 KB

english, 2009

20

Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation

E. Hakonen, J. Ustinov, I. Mathijs, J. Palgi, L. Bouwens, P. J. Miettinen, T. Otonkoski

Journal:

Year:

2011

Language:

english

File:

PDF, 481 KB

english, 2011

21

Nephrin is expressed in the pancreatic beta cells

T. Palmén, H. Ahola, J. Palgi, P. Aaltonen, P. Luimula, S. Wang, I. Jaakkola, M. Knip, T. Otonkoski, H. Holthöfer

Journal:

Year:

2001

Language:

english

File:

PDF, 280 KB

english, 2001

22

Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD)

D. Kelberman, J. P. G. Turton, K. S. Woods, A. Mehta, M. Al-Khawari, J. Greening, P. G. F. Swift, T. Otonkoski, S. J. Rhodes, M. T. Dattani

Journal:

Clinical Endocrinology

Year:

2009

Language:

english

File:

PDF, 215 KB

english, 2009

23

Restricted ethnic diversity in human embryonic stem cell lines

Laurent, Louise C, Nievergelt, Caroline M, Lynch, Candace, Fakunle, Eyitayo, Harness, Julie V, Schmidt, Uli, Galat, Vasiliy, Laslett, Andrew L, Otonkoski, Timo, Keirstead, Hans S

Journal:

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

24

Gene Expression Signatures of Seven Individual Human Embryonic Stem Cell Lines

Heli Skottman, Milla Mikkola, Karolina Lundin, Cia Olsson, Anne-Marie Strömberg, Timo Tuuri, Timo Otonkoski, Outi Hovatta, Riitta Lahesmaa

Journal:

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

25

GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus

Ludvigsson, Johnny, Krisky, David, Casas, Rosaura, Battelino, Tadej, Castaño, Luis, Greening, James, Kordonouri, Olga, Otonkoski, Timo, Pozzilli, Paolo, Robert, Jean-Jacques

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 621 KB

english, 2012

26

Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population

Reimann, F., Huopio, H., Dabrowski, M., Proks, P., Gribble, F.M., Laakso, M., Otonkoski, T., Ashcroft, F.M.

Journal:

Year:

2003

Language:

english

File:

PDF, 289 KB

english, 2003

27

Neonatal Type I diabetes associated with maternal echovirus 6 infection: a case report

Otonkoski, T., Roivainen, M., Vaarala, O., Dinesen, B., Leip&#x000E4, l&#x000E4, , J. A., Hovi, T., Knip, M.

Journal:

Year:

2000

Language:

english

File:

PDF, 57 KB

english, 2000

28

Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms

Meenal Banerjee, Ismo Virtanen, Jaan Palgi, Olle Korsgren, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

29

Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture

Heidi Hongisto, Sanna Vuoristo, Alexandra Mikhailova, Riitta Suuronen, Ismo Virtanen, Timo Otonkoski, Heli Skottman

Journal:

Stem Cell Research

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

30

Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide

Suvi Rasilainen, Jenni M. Nieminen, Anna-Liisa Levonen, Timo Otonkoski, Risto Lapatto

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

31

Laminin isoforms in human embryonic stem cells: synthesis, receptor usage and growth support

Sanna Vuoristo, Ismo Virtanen, Minna Takkunen, Jaan Palgi, Yamato Kikkawa, Patricia Rousselle, Kiyotoshi Sekiguchi, Timo Tuuri, Timo Otonkoski

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

32

Effects of Immunosuppressive Drugs on In Vitro Neogenesis of Human Islets: Mycophenolate Mofetil Inhibits the Proliferation of Ductal Cells

R. Gao, J. Ustinov, O. Korsgren, T. Otonkoski

Journal:

American Journal of Transplantation

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

33

Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland

T Oilinki, T Otonkoski, J Ilonen, M Knip, PJ Miettinen

Journal:

Pediatric Diabetes

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

34

Transcription factor GATA-6 is expressed in the endocrine and GATA-4 in the exocrine pancreas

Ilkka Ketola, Timo Otonkoski, Mari-Anne Pulkkinen, Hannele Niemi, Jaan Palgi, Christina M. Jacobsen, David B. Wilson, Markku Heikinheimo

Journal:

Molecular and Cellular Endocrinology

Year:

2004

Language:

english

File:

PDF, 608 KB

english, 2004

35

Maturation of in vitro-generated human islets after transplantation in nude mice

Ru Gao, Jarkko Ustinov, Olle Korsgren, Milla Mikkola, Karolina Lundin, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2007

Language:

english

File:

PDF, 4.62 MB

english, 2007

36

Weighing up β-cell mass in mice and humans: Self-renewal, progenitors or stem cells?

Neil A. Hanley, Karen Piper Hanley, Päivi J. Miettinen, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

37

Nicotinamide and sodium butyrate for the induction of fetal porci β-cell differentiation prior to transplantation

T. Otonkoski, J. Ustinov, M.-A. Huotari, E. Kallio, P. Häyry

Journal:

Transplantation Proceedings

Year:

1997

Language:

english

File:

PDF, 93 KB

english, 1997

38

A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1

Hanna Huopio, Timo Otonkoski, Ilkka Vauhkonen, Frank Reimann, Frances M Ashcroft, Markku Laakso

Journal:

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

39

Dominantly inherited form of hyperinsulinism caused by a gene mutation in the sulfonylurea receptor 1

Timo Otonkoski, Hanna Huopio, Frank Reimann, Rebecca Ashfield, Markku Laakso, Frances Ashcroft

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

40

Carriers of an inactivating beta-cell K-ATP channel mutation have normally regulated insulin secretion

Hanna Huopio, Ilkka Vauhkonen, Jorma Komulainen, Leo Niskanen, Timo Otonkoski, Markku Laakso

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

41

Transcription factor expression and hormone production in pancreatic AR42J cells

Jaan Palgi, Erik Stumpf, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2000

Language:

english

File:

PDF, 751 KB

english, 2000

42

Traitement par l’antigène GAD65 dans le diabète de type 1 récemment diagnostiqué.

J.J. Robert, J. Ludvigsson, D. Krisky, R. Casas, T. Battelino, L. Castaño, J. Greening, O. Kordonouri, T. Otonkoski, P. Pozzilli, H.J. Veeze, J. Palmer

Journal:

Diabetes & Metabolism

Year:

2012

Language:

french

File:

PDF, 68 KB

french, 2012

43

Over- and Underdosage of SOX3 Is Associated with Infundibular Hypoplasia and Hypopituitarism

Kathryn S. Woods, Maria Cundall, James Turton, Karine Rizotti, Ameeta Mehta, Rodger Palmer, Jacqueline Wong, W.K. Chong, Mahmoud Al-Zyoud, Maryam El-Ali, Timo Otonkoski, Juan-Pedro Martinez-Barbera, Q

Journal:

The American Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 6.62 MB

english, 2005

44

Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells

Timo Otonkoski, Hong Jiao, Nina Kaminen-Ahola, Isabel Tapia-Paez, Mohammed S. Ullah, Laura E. Parton, Frans Schuit, Roel Quintens, Ilkka Sipilä, Ertan Mayatepek, Thomas Meissner, Andrew P. Halestrap,

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 789 KB

english, 2007

45

Lack of glucose-induced functional maturation during long-term culture of human fetal islet cells

Timo Otonkoski, Mikael Knip, Inés Wong, Olli Simell

Journal:

Year:

1991

Language:

english

File:

PDF, 446 KB

english, 1991

46

The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells

Mari-Anne Pulkkinen, Bradley Spencer-Dene, Clive Dickson, Timo Otonkoski

Journal:

Mechanisms of Development

Year:

2003

Language:

english

File:

PDF, 589 KB

english, 2003

47

Unique basement membrane structure of human pancreatic islets: implications for β-cell growth and differentiation

T. Otonkoski, M. Banerjee, O. Korsgren, L.-E. Thornell, I. Virtanen

Journal:

Diabetes, Obesity and Metabolism

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

48

High-throughput karyotyping of human pluripotent stem cells

Riikka J. Lund, Tuomas Nikula, Nelly Rahkonen, Elisa Närvä, Duncan Baker, Neil Harrison, Peter Andrews, Timo Otonkoski, Riitta Lahesmaa

Journal:

Stem Cell Research

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

49

ErbB Signaling Regulates Lineage Determination of Developing Pancreatic Islet Cells in Embryonic Organ Culture

Huotari, Mari-Anne, Miettinen, Päivi J., Palgi, Jaan, Koivisto, Tarja, Ustinov, Jarkko, Harari, Daniel, Yarden, Yosef, Otonkoski, Timo

Journal:

Year:

2002

Language:

english

File:

PDF, 821 KB

english, 2002

50

Small Molecule Inhibitors Promote Efficient Generation of Induced Pluripotent Stem Cells From Human Skeletal Myoblasts

Trokovic, Ras, Weltner, Jere, Manninen, Tuula, Mikkola, Milla, Lundin, Karolina, Hämäläinen, Riikka, Suomalainen, Anu, Otonkoski, Timo

Journal:

Stem Cells and Development

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013