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1

About the reaction of aryl fluorides with sodium sulfide: investigation into the selectivity of substitution of fluorobenzonitriles to yield mercaptobenzonitriles via SNAr displacement of fluorine

Tony Taldone, Pallav D. Patel, Hardik J. Patel, Gabriela Chiosis

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 3.04 MB

english, 2012

2

Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

Caldas-Lopes, E., Cerchietti, L., Ahn, J. H., Clement, C. C., Robles, A. I., Rodina, A., Moulick, K., Taldone, T., Gozman, A., Guo, Y., Wu, N., de Stanchina, E., White, J., Gross, S. S., Ma, Y., Varti

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 1.07 MB

english, 2009

3

Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab

Holland, Jason P., Caldas-Lopes, Eloisi, Divilov, Vadim, Longo, Valerie A., Taldone, Tony, Zatorska, Danuta, Chiosis, Gabriela, Lewis, Jason S., Hashimoto, Kenji

Journal:

Year:

2010

Language:

english

File:

PDF, 814 KB

english, 2010

4

HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons

Kishinevsky, Sarah, Wang, Tai, Rodina, Anna, Chung, Sun Young, Xu, Chao, Philip, John, Taldone, Tony, Joshi, Suhasini, Alpaugh, Mary L., Bolaender, Alexander, Gutbier, Simon, Sandhu, Davinder, Fattahi

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.95 MB

english, 2018

5

The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

Inda, Maria Carmen, Joshi, Suhasini, Wang, Tai, Bolaender, Alexander, Gandu, Srinivasa, Koren III, John, Che, Alicia Yue, Taldone, Tony, Yan, Pengrong, Sun, Weilin, Uddin, Mohammad, Panchal, Palak, Ri

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 3.68 MB

english, 2020

6

ChemInform Abstract: About 1-Triphenylmethyl-3-tert-butylaziridinone and Some of Its Reactions.

Istvan Lengyel, Victor Cesare, Halina Karram, Tony Taldone

Journal:

Year:

2001

File:

PDF, 29 KB

2001

7

ChemInform Abstract: About the Reaction of 2,3-Dibromo-2-methyl-N-(1-adamantyl)propanamide with Sodium tert-Butoxide. A Competition Experiment.

Istvan Lengyel, Victor Cesare, Tony Taldone

Journal:

Year:

2001

File:

PDF, 32 KB

2001

8

ChemInform Abstract: About Four New Trityl-Substituted α-Lactams.

Istvan Lengyel, Victor Cesare, Ian Adam, Tony Taldone

Journal:

Year:

2002

File:

PDF, 30 KB

2002

9

About the Factors Which Govern the Ring-Opening of α-Lactams with Primary Amines. Part 2. The Relative Basicity of the Amine.

Victor Cesare, Tony Taldone, Istvan Lengyel

Journal:

Year:

2003

File:

PDF, 165 KB

2003

10

A Direct Link Between the Passerini Reaction and α-Lactams.

Istvan Lengyel, Victor Cesare, Tony Taldone

Journal:

Year:

2004

File:

PDF, 128 KB

2004

11

About 1-triphenylmethyl-3-tert-butylaziridinone and some of its reactions

István Lengyel, Victor Cesare, Halina Karram, Tony Taldone

Journal:

Journal of Heterocyclic Chemistry

Year:

2001

Language:

english

File:

PDF, 77 KB

english, 2001

12

Full Characterization and some reactions of 1-(2-adamantyl)-3-(1-adamantyl)aziridin-2-one

István Lengyel, Tony Taldone, Theresa Lyons, Victor Cesare

Journal:

Journal of Heterocyclic Chemistry

Year:

2008

Language:

english

File:

PDF, 844 KB

english, 2008

13

A facile and efficient synthesis of d6-labeled PU-H71, a purine-scaffold Hsp90 inhibitor

Tony Taldone, Danuta Zatorska, Yanlong Kang, Gabriela Chiosis

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2010

Language:

english

File:

PDF, 146 KB

english, 2010

14

Design of a fluorescence polarization assay platform for the study of human Hsp70

Yanlong Kang, Tony Taldone, Cristina C. Clement, Sheara W. Fewell, Julia Aguirre, Jeffrey L. Brodsky, Gabriela Chiosis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 212 KB

english, 2008

15

Discovery and development of heat shock protein 90 inhibitors

Tony Taldone, Weilin Sun, Gabriela Chiosis

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 409 KB

english, 2009

16

Inhibition of dipeptidyl peptidase-IV (DPP-IV) by atorvastatin

Tony Taldone, S. William Zito, Tanaji T. Talele

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 313 KB

english, 2008

17

Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines

Hui Tao, Yanlong Kang, Tony Taldone, Gabriela Chiosis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

18

α-Glucosidase inhibitory activity of Syzygium cumini (Linn.) Skeels seed kernel in vitro and in Goto–Kakizaki (GK) rats

Jayantrao Shinde, Tony Taldone, Michael Barletta, Naveen Kunaparaju, Bo Hu, Sunil Kumar, Jessica Placido, S. William Zito

Journal:

Carbohydrate Research

Year:

2008

Language:

english

File:

PDF, 116 KB

english, 2008

19

A direct link between the Passerini reaction and α-lactams

István Lengyel, Victor Cesare, Tony Taldone

Journal:

Year:

2004

Language:

english

File:

PDF, 395 KB

english, 2004

20

Heat shock protein 90 in neurodegenerative diseases

Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis

Journal:

Molecular Neurodegeneration

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010

21

Design, synthesis, and evaluation of small molecule Hsp90 probes

Tony Taldone, Danuta Zatorska, Pallav D. Patel, Hongliang Zong, Anna Rodina, James H. Ahn, Kamalika Moulick, Monica L. Guzman, Gabriela Chiosis

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 872 KB

english, 2011

22

ChemInform Abstract: Reaction of 2-Naphthylamine with Sodium Iodate/Sodium Sulfite: Synthesis of 2-Amino-1-iodonaphthalene.

Tony Taldone, Danuta Zatorska, Gabriela Chiosis

Journal:

Year:

2012

File:

PDF, 22 KB

2012

23

Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

Komal Jhaveri, Tony Taldone, Shanu Modi, Gabriela Chiosis

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

24

Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy

Tony Taldone, Erica M. Gomes-DaGama, Hongliang Zong, Siddhartha Sen, Mary L. Alpaugh, Danuta Zatorska, Raul Alonso-Sabadell, Monica L. Guzman, Gabriela Chiosis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 511 KB

english, 2011

25

ChemInform Abstract: Reaction of Aryl Fluorides with Sodium Sulfide: Investigation into the Selectivity of Substitution of Fluorobenzonitriles to Yield Mercaptobenzonitriles via SNAr Displacement of Fluorine.

Tony Taldone, Pallav D. Patel, Hardik J. Patel, Gabriela Chiosis

Journal:

Year:

2012

File:

PDF, 32 KB

2012

26

Targeting Hsp90: small-molecule inhibitors and their clinical development

Tony Taldone, Alexander Gozman, Ronnie Maharaj, Gabriela Chiosis

Journal:

Current Opinion in Pharmacology

Year:

2008

Language:

english

File:

PDF, 246 KB

english, 2008

27

Studying the S-nitrosylation of model peptides and eNOS protein by mass spectrometry

Frank S. Taldone, Monorama Tummala, Eric J. Goldstein, Victor Ryzhov, Kandasamy Ravi, Stephen M. Black

Journal:

Year:

2005

Language:

english

File:

PDF, 684 KB

english, 2005

28

INTRAMYOCARDIAL STEM CELL INJECTION CAN REVERSE THE LEFT VENTRICULAR SPHERICAL REMODELING OF ISCHEMIC CARDIOMYOPATHY: TURNING SOCCER BALLS INTO (AMERICAN) FOOTBALLS

Frederic C. McCall, Sabrina N. Taldone, Viky Y. Suncion, Vasileios Karantalis, Darcy L. Velazquez, Joel Fishman, Barry Trachtenberg, Pradip M. Pattany, Adam R. Williams, Juan P. Zambrano, Alan W. Held

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 178 KB

english, 2012

29

Preparation of a Diverse Purine-Scaffold Library via One-Step Palladium Catalyzed Cross-Coupling

Taldone, Tony, Zatorska, Danuta, J. Patel, Hardik, Sun, Weilin, R. Patel, Maulik, Chiosis, Gabriela

Journal:

Year:

2013

Language:

english

File:

PDF, 895 KB

english, 2013

30

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Taldone, Tony, Patel, Pallav D., Patel, Maulik, Patel, Hardik J., Evans, Christopher E., Rodina, Anna, Ochiana, Stefan, Shah, Smit K., Uddin, Mohammad, Gewirth, Daniel, Chiosis, Gabriela

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

31

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

Patel, Pallav D, Yan, Pengrong, Seidler, Paul M, Patel, Hardik J, Sun, Weilin, Yang, Chenghua, Que, Nanette S, Taldone, Tony, Finotti, Paola, Stephani, Ralph A, Gewirth, Daniel T, Chiosis, Gabriela

Journal:

Nature Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

32

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

Miller, Justine D., Ganat, Yosif M., Kishinevsky, Sarah, Bowman, Robert L., Liu, Becky, Tu, Edmund Y., Mandal, Pankaj K., Vera, Elsa, Shim, Jae-won, Kriks, Sonja, Taldone, Tony, Fusaki, Noemi, Tomishi

Journal:

Year:

2013

Language:

english

File:

PDF, 5.19 MB

english, 2013

33

Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

Rodina, Anna, Patel, Pallav D., Kang, Yanlong, Patel, Yogita, Baaklini, Imad, Wong, Michael J.H., Taldone, Tony, Yan, Pengrong, Yang, Chenghua, Maharaj, Ronnie, Gozman, Alexander, Patel, Maulik R., Pa

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

34

Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

Ambati, Srikanth R., Lopes, Eloisi Caldas, Kosugi, Kohji, Mony, Ullas, Zehir, Ahmet, Shah, Smit K., Taldone, Tony, Moreira, Andre L., Meyers, Paul A., Chiosis, Gabriela, Moore, Malcolm A.S.

Journal:

Molecular Oncology

Year:

2014

Language:

english

File:

PDF, 2.54 MB

english, 2014

35

Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

Taldone, Tony, Kang, Yanlong, Patel, Hardik J., Patel, Maulik R., Patel, Pallav D., Rodina, Anna, Patel, Yogita, Gozman, Alexander, Maharaj, Ronnie, Clement, Cristina C., Lu, Alvin, Young, Jason C., C

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.95 MB

english, 2014

36

Protein chaperones: a composition of matter review (2008 – 2013)

Taldone, Tony, Patel, Hardik J, Bolaender, Alexander, Patel, Maulik R, Chiosis, Gabriela

Journal:

Expert Opinion on Therapeutic Patents

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

37

Author index

Rodina, Anna, Taldone, Tony, Kang, Yanlong, Patel, Pallav D., Koren, John, Yan, Pengrong, DaGama Gomes, Erica M., Yang, Chenghua, Patel, Maulik R., Shrestha, Liza, Ochiana, Stefan O., Santarossa, Cris

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1994

Language:

english

File:

PDF, 254 KB

english, 1994

38

Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

Rodina, Anna, Taldone, Tony, Kang, Yanlong, Patel, Pallav D., Koren, John, Yan, Pengrong, DaGama Gomes, Erica M., Yang, Chenghua, Patel, Maulik R., Shrestha, Liza, Ochiana, Stefan O., Santarossa, Cris

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 5.07 MB

english, 2014

39

Synthesis of Reblastatin, Autolytimycin, and Non-Benzoquinone Analogues: Potent Inhibitors of Heat Shock Protein 90

Wrona, Iwona E., Gozman, Alexander, Taldone, Tony, Chiosis, Gabriela, Panek, James S.

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 3.80 MB

english, 2010

40

Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

Kang, Yanlong, Taldone, Tony, Patel, Hardik J., Patel, Pallav D., Rodina, Anna, Gozman, Alexander, Maharaj, Ronnie, Clement, Cristina C., Patel, Maulik R., Brodsky, Jeffrey L., Young, Jason C., Chiosi

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 4.71 MB

english, 2014

41

ABOUT THE REACTION OF 2,3-DIBROMO-2-METHYL-N-(1-ADAMANTYL)-PROPANAMIDE WITH SODIUM TERT -BUTOXIDE. A COMPETITION EXPERIMENT

Lengyel, István, Cesare, Victory, Taldone, Tony

Journal:

Synthetic Communications

Year:

2001

Language:

english

File:

PDF, 198 KB

english, 2001

42

THE SYNTHESIS, PHYSICAL, AND SPECTRAL PROPERTIES, AND SOME REACTIONS OF A NEW STABLE bis -α-LACTAM (AZIRIDINONE) WITH A TERPENE SKELETON

Lengyel, Istvan, Cesare, Victor, Taldone, Tony, Uliss, David

Journal:

Synthetic Communications

Year:

2001

Language:

english

File:

PDF, 254 KB

english, 2001

43

Selective targeting of the stress chaperome as a therapeutic strategy

Taldone, Tony, Ochiana, Stefan O., Patel, Pallav D., Chiosis, Gabriela

Journal:

Trends in Pharmacological Sciences

Year:

2014

Language:

english

File:

PDF, 2.41 MB

english, 2014

44

Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment

Patel, Hardik J, Modi, Shanu, Chiosis, Gabriela, Taldone, Tony

Journal:

Expert Opinion on Drug Discovery

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

45

Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally or Globally?: An Analysis From the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) Randomized Trial

Suncion, V. Y., Ghersin, E., Fishman, J. E., Zambrano, J. P., Karantalis, V., Mandel, N., Nelson, K. H., Gerstenblith, G., DiFede Velazquez, D. L., Breton, E., Sitammagari, K., Schulman, I. H., Taldon

Journal:

Circulation Research

Year:

2014

Language:

english

File:

PDF, 1.96 MB

english, 2014

46

Structure elucidation and inhibitory effects on human platelet aggregation of chlorogenic acid from Wrightia tinctoria

Amin, Ripal P., Kunaparaju, Naveen, Kumar, Sunil, Taldone, Tony, Barletta, Michael A., Zito, S. William

Journal:

Journal of Complementary and Integrative Medicine

Year:

2013

Language:

english

File:

PDF, 615 KB

english, 2013

47

Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90

Taldone, Tony, Gillan, Victoria, Sun, Weilin, Rodina, Anna, Patel, Pallav, Maitland, Kirsty, O'Neill, Kerry, Chiosis, Gabriela, Devaney, Eileen, Knight, Matty

Journal:

PLoS Neglected Tropical Diseases

Year:

2010

Language:

english

File:

PDF, 361 KB

english, 2010

48

Reaction of 2-Naphthylamine with Sodium Iodate/Sodium Sulfite: Synthesis of 2-Amino-1-iodonaphthalene

Taldone, Tony, Zatorska, Danuta, Chiosis, Gabriela

Journal:

Synthetic Communications

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

49

Group-Based Differences in Anti-Aging Bias Among Medical Students

Ruiz, Jorge G., Andrade, Allen D., Anam, Ramanakumar, Taldone, Sabrina, Karanam, Chandana, Hogue, Christie, Mintzer, Michael J.

Journal:

Gerontology & Geriatrics Education

Year:

2015

Language:

english

File:

PDF, 195 KB

english, 2015

50

Stem Cell and Gene Therapy for Cardiovascular Disease || Allogeneic versus Autologous Source

Taldone, Sabrina

Year:

2016

Language:

english

File:

PDF, 2.99 MB

english, 2016

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