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51

Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology

Nedić, O., Rattan, S. I. S., Grune, T., Trougakos, I. P.

Journal:

Free Radical Research

Year:

2013

Language:

english

File:

PDF, 214 KB

english, 2013

52

Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases

Trougakos, Ioannis P., Gonos, Efstathios S.

Journal:

Free Radical Research

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

53

The recovery potential of intrinsically versus extrinsically motivated off-job activities

ten Brummelhuis, Lieke L., Trougakos, John P.

Journal:

Journal of Occupational and Organizational Psychology

Year:

2014

Language:

english

File:

PDF, 250 KB

english, 2014

54

Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging

Tsakiri, Eleni N., Sykiotis, Gerasimos P., Papassideri, Issidora S., Terpos, Evangelos, Dimopoulos, Meletios A., Gorgoulis, Vassilis G., Bohmann, Dirk, Trougakos, Ioannis P.

Journal:

Year:

2013

Language:

english

File:

PDF, 519 KB

english, 2013

55

CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor

Leskov, K. S., Araki, S., Lavik, J.-P., Gomez, J. A., Gama, V., Gonos, E. S., Trougakos, I. P., Matsuyama, S., Boothman, D. A.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.92 MB

english, 2011

56

Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins

Sideridou, M., Zakopoulou, R., Evangelou, K., Liontos, M., Kotsinas, A., Rampakakis, E., Gagos, S., Kahata, K., Grabusic, K., Gkouskou, K., Trougakos, I. P., Kolettas, E., Georgakilas, A. G., Volarevi

Journal:

The Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 4.72 MB

english, 2011

57

Silencing Expression of the Clusterin/Apolipoprotein J Gene in Human Cancer Cells Using Small Interfering RNA Induces Spontaneous Apoptosis, Reduced Growth Ability, and Cell Sensitization to Genotoxic and Oxidative Stress

Trougakos, I. P.

Journal:

Cancer Research

Year:

2004

Language:

english

File:

PDF, 487 KB

english, 2004

58

Structural studies and cytotoxicity assays of “aggregation-prone” IAPP 8-16 and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin

Louros, Nikolaos N., Tsiolaki, Paraskevi L., Zompra, Aikaterini A., Pappa, Eleni V., Magafa, Vassiliki, Pairas, George, Cordopatis, Paul, Cheimonidou, Christina, Trougakos, Ioannis P., Iconomidou, Vas

Journal:

Year:

2015

Language:

english

File:

PDF, 3.01 MB

english, 2015

59

Central Role of the Proteasome in Senescence and Survival of Human Fibroblasts: INDUCTION OF A SENESCENCE-LIKE PHENOTYPE UPON ITS INHIBITION AND RESISTANCE TO STRESS UPON ITS ACTIVATION

Chondrogianni, N., Stratford, F. L. L., Trougakos, I. P., Friguet, B., Rivett, A. J., Gonos, E. S.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 585 KB

english, 2003

60

Biological Monitoring of Hexavalent Chromium and Serum Levels of the Senescence Biomarker Apolipoprotein J/Clusterin in Welders

Alexopoulos, Evangelos C., Cominos, Xenophon, Trougakos, Ioannis P., Lourda, Magda, Gonos, Efstathios S., Makropoulos, Vassilios

Journal:

Bioinorganic Chemistry and Applications

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

61

Advances and Challenges in Basic and Translational Research on Clusterin

Trougakos, I. P., Djeu, J. Y., Gonos, E. S., Boothman, D. A.

Journal:

Cancer Research

Year:

2009

Language:

english

File:

PDF, 166 KB

english, 2009

62

The Molecular Chaperone Apolipoprotein J/Clusterin as a Sensor of Oxidative Stress: Implications in Therapeutic Approaches - A Mini-Review

Trougakos, Ioannis P.

Journal:

Year:

2013

Language:

english

File:

PDF, 577 KB

english, 2013

63

Induction of Clusterin by AKT--Role in Cytoprotection against Docetaxel in Prostate Tumor Cells

Zhong, B., Sallman, D. A., Gilvary, D. L., Pernazza, D., Sahakian, E., Fritz, D., Cheng, J. Q., Trougakos, I., Wei, S., Djeu, J. Y.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 459 KB

english, 2010

64

Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts

Sklirou, Aimilia D., Ralli, Marianna, Dominguez, Maria, Papassideri, Issidora, Skaltsounis, Alexios-Leandros, Trougakos, Ioannis P.

Journal:

Year:

2015

Language:

english

File:

PDF, 4.15 MB

english, 2015

65

Intracellular Clusterin Inhibits Mitochondrial Apoptosis by Suppressing p53-Activating Stress Signals and Stabilizing the Cytosolic Ku70-Bax Protein Complex

Trougakos, I. P., Lourda, M., Antonelou, M. H., Kletsas, D., Gorgoulis, V. G., Papassideri, I. S., Zou, Y., Margaritis, L. H., Boothman, D. A., Gonos, E. S.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 985 KB

english, 2009

66

Exploring and exploiting the systemic effects of deregulated replication licensing

Petrakis, Theodoros G., Komseli, Eirini-Stavroula, Papaioannou, Marilena, Vougas, Kostas, Polyzos, Alexandros, Myrianthopoulos, Vassilios, Mikros, Emmanuel, Trougakos, Ioannis P., Thanos, Dimitris, Br

Journal:

Seminars in Cancer Biology

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

67

[Research in Occupational Stress and Well-being] Research in Occupational Stress and Well-being Volume 7 ||

Trougakos, John P., Hideg, Ivona

Year:

2009

Language:

english

File:

PDF, 373 KB

english, 2009

68

Progression of mouse skin carcinogenesis is associated with the orchestrated deregulation of mir-200 family members, mir-205 and their common targets

Skourti, Elena, Logotheti, Stella, Kontos, Christos K., Pavlopoulou, Athanasia, Dimoragka, Paraskevi T., Trougakos, Ioannis P., Gorgoulis, Vassilis, Scorilas, Andreas, Michalopoulos, Ioannis, Zoumpour

Journal:

Molecular Carcinogenesis

Year:

2016

Language:

english

File:

PDF, 5.72 MB

english, 2016

69

Affect spin and the emotion regulation process at work.

Beal, Daniel J., Trougakos, John P., Weiss, Howard M., Dalal, Reeshad S.

Journal:

Journal of Applied Psychology

Year:

2013

Language:

english

File:

PDF, 260 KB

english, 2013

70

Erratum to ‘Exploring and exploiting the systemic effects of deregulated replication licensing’ [Seminars in Cancer Biology 37–38C, (2016) 3–15]

Petrakis, Theodoros G., Komseli, Eirini-Stavroula, Papaioannou, Marilena, Vougas, Kostas, Polyzos, Alexandros, Myrianthopoulos, Vassilios, Mikros, Emmanuel, Trougakos, Ioannis P., Thanos, Dimitris, Br

Journal:

Seminars in Cancer Biology

Year:

2017

Language:

english

File:

PDF, 162 KB

english, 2017

71

The unexpected function of a highly conserved YXXΦ motif in HCV core protein

Karamichali, Eirini, Serti, Elisavet, Gianneli, Aikaterini, Papaefthymiou, Aikaterini, Kakkanas, Athanassios, Foka, Pelagia, Seremetakis, Alexandros, Katsarou, Konstantina, Trougakos, Ioannis P., Geor

Journal:

Infection, Genetics and Evolution

Year:

2017

Language:

english

File:

PDF, 2.62 MB

english, 2017

72

6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts

Sklirou, Aimilia D., Gaboriaud-Kolar, Nicolas, Papassideri, Issidora, Skaltsounis, Alexios-Leandros, Trougakos, Ioannis P.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 8.31 MB

english, 2017

73

Cancer chemoprevention via activation of proteostatic modules

Sklirou, Aimilia, Papanagnou, Eleni-Dimitra, Fokialakis, Nikolaos, Trougakos, Ioannis P.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.16 MB

english, 2017

74

Changing Patterns of Bacterial Nosocomial Infections: A Nine-Year Study in a General Hospital

Maniatis, A.N., Trougakos, I.P., Katsanis, G., Palermos, J., Maniatis, N.A., Legakis, N.J.

Journal:

Year:

1997

Language:

english

File:

PDF, 931 KB

english, 1997

75

The NFE2-related transcription factor 2 (Nrf2) coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland

Ziros, Panos G, Habeos, Ioannis, Chartoumpekis, Dionysios V, Ntalampyra, Eleni, Somm, Emmanuel, Renaud, Cédric O, Bongiovanni, Massimo, Trougakos, Ioannis P, Yamamoto, Masayuki, Kensler, Thomas W, San

Journal:

Year:

2018

Language:

english

File:

PDF, 2.94 MB

english, 2018

76

Integrating the DNA damage and protein stress responses during cancer development and treatment

Gorgoulis, Vassilis G., Pefani, Dafni-Eleftheria, Pateras, Ioannis S., Trougakos, Ioannis P.

Journal:

The Journal of Pathology

Year:

2018

Language:

english

File:

PDF, 1.74 MB

english, 2018

77

Apolipoprotein J/Clusterin in Human Erythrocytes Is Involved in the Molecular Process of Defected Material Disposal during Vesiculation

Antonelou, Marianna H., Kriebardis, Anastasios G., Stamoulis, Konstantinos E., Trougakos, Ioannis P., Papassideri, Issidora S., Chammas, Roger

Journal:

Year:

2011

Language:

english

File:

PDF, 797 KB

english, 2011

78

Apolipoprotein J/Clusterin Is a Novel Structural Component of Human Erythrocytes and a Biomarker of Cellular Stress and Senescence

Antonelou, Marianna H., Kriebardis, Anastasios G., Stamoulis, Konstantinos E., Trougakos, Ioannis P., Papassideri, Issidora S., Chammas, Roger

Journal:

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

79

Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease

Gumeni, Sentiljana, Trougakos, Ioannis P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2016

Language:

english

File:

PDF, 2.05 MB

english, 2016

80

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

Voutetakis, Konstantinos, Chatziioannou, Aristotelis, Gonos, Efstathios S., Trougakos, Ioannis P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

81

Redox Status and Proteostasis in Ageing and Disease

Rizzi, Federica, Trougakos, Ioannis P., Pintus, Gianfranco, Sykiotis, Gerasimos P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

82

Proteome Stability as a Key Factor of Genome Integrity

Gumeni, Sentiljana, Evangelakou, Zoi, Gorgoulis, Vassilis, Trougakos, Ioannis

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

83

Anti-Melanogenic Properties of Greek Plants. A Novel Depigmenting Agent from Morus alba Wood

Chaita, Eliza, Lambrinidis, George, Cheimonidi, Christina, Agalou, Adamantia, Beis, Dimitris, Trougakos, Ioannis, Mikros, Emmanuel, Skaltsounis, Alexios-Leandros, Aligiannis, Nektarios

Journal:

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017

84

Phytochemical Composition of the Decoctions of Greek Edible Greens (Chórta) and Evaluation of Antioxidant and Cytotoxic Properties

Mikropoulou, Eleni, Vougogiannopoulou, Konstantina, Kalpoutzakis, Eleftherios, Sklirou, Aimilia, Skaperda, Zoi, Houriet, Joëlle, Wolfender, Jean-Luc, Trougakos, Ioannis, Kouretas, Dimitrios, Halabalak

Journal:

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

85

Targeting Protein Quality Control Mechanisms by Natural Products to Promote Healthy Ageing

Wedel, Sophia, Manola, Maria, Cavinato, Maria, Trougakos, Ioannis, Jansen-Dürr, Pidder

Journal:

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

86

The proteasome inhibitor carfilzomib (Cfz) induces cardiotoxicity in vivo: molecular mechanisms and the cardioprotective effect of metformin (Met)

Kremastiotis, G., Efentakis, P., Varela, A., Davos, C.H., Tsoumani, M., Papanagnou, E.D., Trougakos, I.P., Kastritis, E., Kanaki, Z., Iliodromitis, E.K., Klinakis, A., Dimopoulos, M.A., Terpos, E., An

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2018

Language:

english

File:

PDF, 45 KB

english, 2018

87

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Tsakiri, Eleni N., Gumeni, Sentiljana, Iliaki, Kalliopi K., Benaki, Dimitra, Vougas, Konstantinos, Sykiotis, Gerasimos P., Gorgoulis, Vassilis G., Mikros, Emmanuel, Scorrano, Luca, Trougakos, Ioannis

Journal:

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

88

Comparison survey of EVOO polyphenols and exploration of healthy aging-promoting properties of oleocanthal and oleacein

Nikou, Theodora, Liaki, Vasiliki, Stathopoulos, Panagiotis, Sklirou, Aimilia D., Tsakiri, Eleni N., Jakschitz, Thomas, Bonn, Günther, Trougakos, Ioannis P., Halabalaki, Maria, Skaltsounis, Leandros A.

Journal:

Food and Chemical Toxicology

Year:

2019

File:

PDF, 2.03 MB

2019

89

Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues

Georgakopoulou, EA, Tsimaratou, K, Evangelou, K, Fernandez, Marcos-PJ, Zoumpourlis, V, Trougakos, IP, Kletsas, D, Bartek, J, Serrano, M, Gorgoulis, VG

Journal:

Year:

2012

File:

PDF, 4.60 MB

2012

90

P4787Investigating the molecular mechanisms of carfilzomib-induced cardiotoxicity and the emerging role of metformin as a prophylactic therapy

Kremastiotis, G, Efentakis, P, Varela, A, Davos, C H, Papanagnou, E.-D, Trougakos, I P, Kastritis, E, Kanaki, Z, Iliodromitis, E K, Klinakis, A, Dimopoulos, M A, Terpos, E, Andreadou, I

Journal:

European Heart Journal

Year:

2018

Language:

english

File:

PDF, 91 KB

english, 2018

91

Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues

Georgakopoulou, EA, Tsimaratou, K, Evangelou, K, Fernandez, Marcos-PJ, Zoumpourlis, V, Trougakos, IP, Kletsas, D, Bartek, J, Serrano, M, Gorgoulis, VG

Journal:

Year:

2012

Language:

english

File:

PDF, 4.60 MB

english, 2012

92

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

Tsakiri, Eleni N., Gumeni, Sentiljana, Vougas, Konstantinos, Pendin, Diana, Papassideri, Issidora, Daga, Andrea, Gorgoulis, Vassilis, Juhász, Gábor, Scorrano, Luca, Trougakos, Ioannis P.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.91 MB

english, 2019

93

Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach

Evangelakou, Zoi, Manola, Maria, Gumeni, Sentiljana, Trougakos, Ioannis P.

Journal:

Genes & Nutrition

Year:

2019

Language:

english

File:

PDF, 2.39 MB

english, 2019

94

Terrestrial Microorganisms: Cell Factories of Bioactive Molecules with Skin Protecting Applications

Peyrat,, Tsafantakis,, Georgousaki,, Ouazzani,, Genilloud,, Trougakos,, Fokialakis,

Journal:

Year:

2019

Language:

english

File:

PDF, 2.08 MB

english, 2019

95

Cercospora sp. as a source of anti-aging polyketides targeting 26S proteasome and scale-up production in submerged bioreactor

Georgousaki, Katerina, Tsafantakis, Nikolaos, Gumeni, Sentiljana, González-Menéndez, Victor, de Pedro, Nuria, Tormo, José Rubén, Almeida, Celso, Lambert, Carole, Genilloud, Olga, Trougakos, Ioannis P.

Journal:

Journal of Biotechnology

Year:

2019

Language:

english

File:

PDF, 1.51 MB

english, 2019

96

Osmanicin, a Polyketide Alkaloid Isolated from Streptomyces osmaniensis CA-244599 Inhibits Elastase in Human Fibroblasts

Samy, Mamdouh N., Le Goff, Géraldine, Lopes, Philippe, Georgousaki, Katerina, Gumeni, Sentiljana, Almeida, Celso, González, Ignacio, Genilloud, Olga, Trougakos, Ioannis, Fokialakis, Nikolas, Ouazzani,

Journal:

Year:

2019

Language:

english

File:

PDF, 2.61 MB

english, 2019

97

What sustains the multidrug resistance phenotype beyond ABC efflux transporters? Looking beyond the tip of the iceberg

Alexa-Stratulat, Teodora, Pešić, Milica, Gašparović, Ana Čipak, Trougakos, Ioannis P., Riganti, Chiara

Journal:

Drug Resistance Updates

Year:

2019

Language:

english

File:

PDF, 2.45 MB

english, 2019

98

Nrf2, stress and aging

Trougakos, Ioannis P.

Journal:

Year:

2019

Language:

english

File:

PDF, 518 KB

english, 2019

99

Nrf2, stress and aging

Trougakos, Ioannis P.

Journal:

Year:

2019

File:

PDF, 518 KB

2019

100

The emergence of drug resistance to targeted therapies: Clinical evidence

Sarmento-Ribeiro, Ana Bela, Scorilas, Andreas, Gonçalves, Ana Cristina, Efferth, Thomas, Trougakos, Ioannis P.

Journal:

Drug Resistance Updates

Year:

2019

Language:

english

File:

PDF, 7.92 MB

english, 2019