van Bladeren, P. J.: search on Z-Library

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51

β-Naphthoflavone- and self-induced metabolism of 3,3′,4,4′-tetrachlorobiphenyl in hepatic microsomes of the male, pregnant female and foetal rat

Morse, D. C., Van Bladeren, P. J., Wehler, E. Klasson, Brouwer, A.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.25 MB

english, 1995

52

ChemInform Abstract: Resolution and Absolute Configuration of K-Region trans-Dihydrodiols from Polycyclic Aromatic Hydrocarbons.

BALANI, S. K., VAN BLADEREN, P. J., SHIRAI, N., JERINA, D. M.

Journal:

Chemischer Informationsdienst

Year:

1986

File:

PDF, 88 KB

1986

53

Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells

Walter Brand, Berend Oosterhuis, Peter Krajcsi, Denis Barron, Fabiola Dionisi, Peter J. van Bladeren, Ivonne M. C. M. Rietjens, Gary Williamson

Journal:

Biopharmaceutics & Drug Disposition

Year:

2011

Language:

english

File:

PDF, 215 KB

english, 2011

54

Toxicology of chemical mixtures: challenges for today and the future

V.J. Feron, J.P. Groten, D. Jonker, F.R. Cassee, P.J. van Bladeren

Journal:

Year:

1995

Language:

english

File:

PDF, 1.31 MB

english, 1995

55

Modulating hesperetin bioavailability at the level of its intestinal metabolism and ABC transporter mediated efflux studied in Caco-2 monolayers

W. Brand, P.A.I. van der Wel, G. Williamson, P.J. van Bladeren, I.M.C.M. Rietjens

Journal:

Chemico-Biological Interactions

Year:

2007

Language:

english

File:

PDF, 92 KB

english, 2007

56

Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling

Jan J.P Bogaards, Andreas P Freidig, Peter J van Bladeren

Journal:

Chemico-Biological Interactions

Year:

2001

Language:

english

File:

PDF, 190 KB

english, 2001

57

Prediction of interindividual variation in drug plasma levels in vivo from individual enzyme kinetic data and physiologically based pharmacokinetic modeling

Jan J.P. Bogaards, Erna M. Hissink, Mike Briggs, Richard Weaver, Roeline Jochemsen, Peter Jackson, Marc Bertrand, Peter J. van Bladeren

Journal:

European Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 159 KB

english, 2000

58

Effects of cooked brussels sprouts on cytochrome p-450 profile and phase II enzymes in liver and small intestinal mucosa of the rat

H.M. Wortelboer, C.A. de Kruif, A.A.J. van Iersel, J. Noordhoek, B.J. Blaauboer, P.J. van Bladeren, H.E. Falke

Journal:

Food and Chemical Toxicology

Year:

1992

Language:

english

File:

PDF, 838 KB

english, 1992

59

Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes

van der Aar, E. M., Buikema, D., Commandeur, J. N. M., Te Koppele, J. M., van Ommen, B., Van Bladeren, P. J., Vermeulen, N. P. E.

Journal:

Year:

1996

Language:

english

File:

PDF, 868 KB

english, 1996

60

Stereoselective Conjugation, Transport and Bioactivity of S - and R -Hesperetin Enantiomers in Vitro

Brand, Walter, Shao, Jia, Hoek-van den Hil, Elisabeth F., van Elk, Kathelijn N., Spenkelink, Bert, de Haan, Laura H. J., Rein, Maarit J., Dionisi, Fabiola, Williamson, Gary, van Bladeren, Peter J., Ri

Journal:

Journal of Agricultural and Food Chemistry

Year:

2010

Language:

english

File:

PDF, 954 KB

english, 2010

61

Cytochrome P450-Catalyzed Oxidation of Halobenzene Derivatives

Rietjens, Ivonne M. C. M., den Besten, Cathaline, Hanzlik, Robert P., van Bladeren, Peter J.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 231 KB

english, 1997

62

Metabolism and biochemical effects of 3,3′,4,4′-tetrachlorobiphenyl in pregnant and fetal rats

Dennis C. Morse, Eva Klasson Wehler, Maribel van de Pas, Albert Th.H.J. de Bie, Peter J. van Bladeren, Abraham Brouwer

Journal:

Chemico-Biological Interactions

Year:

1995

Language:

english

File:

PDF, 1.22 MB

english, 1995

63

Inter-individual variability in the oxidation of 1,2-dibromoethane: use of heterologously expressed human cytochrome P450 and human liver microsomes

Lars W. Wormhoudt, Jan H.T.M. Ploemen, Isabelle de Waziers, Jan N.M. Commandeur, Philippe H. Beaune, Peter J. van Bladeren, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1996

Language:

english

File:

PDF, 1.26 MB

english, 1996

64

Corrigendum to “Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect” [Toxicology and Applied Pharmacology (2010) 179–190]

W. Alhusainy, A. Paini, A. Punt, J. Louisse, A. Spenkelink, J. Vervoort, T. Delatour, G. Scholz, B. Schilter, T. Adams, P.J. van Bladeren, I.M.C.M. Rietjens

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 101 KB

english, 2010

65

Comparison of Renal Toxicity after Long-Term Oral Administration of Cadmium Chloride and Cadmium-Metallothionein in Rats

J.P. Groten, J.H. Koeman, J.H.J. van Nesselrooij, J.B. Luten, J.M.Fentener van Vlissingen, W.S. Stenhuis, P.J. van Bladeren

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 700 KB

1994

66

Microsomal glutathione transferase: Lipid-derived substrates and lipid dependence

Erifili Mosialou, Fiorella Piemonte, Claes Andersson, Ria M.E. Vos, Peter J. van Bladeren, Ralf Morgenstern

Journal:

Archives of Biochemistry and Biophysics

Year:

1995

Language:

english

File:

PDF, 789 KB

english, 1995

67

The glutathione conjugates of tert-butyl hydroquinone as potent redox cycling agents and possible reactive agents underlying the toxicity of butylated hydroxyanisole

Ben van Ommen, Arjen Koster, Hans Verhagen, Peter J. van Bladeren

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 426 KB

english, 1992

68

Interindividual differences in the in vitro conjugation of methylene chloride with glutathione by cytosolic glutathione S-transferase in 22 human liver samples

Jan J.P. Bogaards, Ben van Ommen, Peter J. Van Bladeren

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 404 KB

english, 1993

69

Polymorphism in the glutathione conjugation activity of human erythrocytes towards ethylene dibromide and 1,2-epoxy-3-(p-nitrophenoxy)-propane

Jan H.T.M. Ploemen, Lars W. Wormhoudt, Ben van Ommen, Jan N.M. Commandeur, Nico P.E. Vermeulen, Peter J. van Bladeren

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1995

Language:

english

File:

PDF, 910 KB

english, 1995

70

Conversion of Pentahalogenated Phenols by Microperoxidase-8/H 2 O 2 to Benzoquinone-Type Products

Osman, Ahmed M., Posthumus, Maarten A., Veeger, Cees, van Bladeren, Peter J., Laane, Colja, Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 247 KB

english, 1998

71

Stereoselective oxidation of styrene to styrene oxide in rats as measured by mercapturic acid excretion

Delbressine, L. P. C., Van Bladeren, P. J., Smeets, F. L. M., Seutter-Berlage, F.

Journal:

Year:

1981

Language:

english

File:

PDF, 483 KB

english, 1981

72

Militaire apothekers

D. van Bladeren

Journal:

International Journal of Clinical Pharmacy

Year:

1980

Language:

dutch

File:

PDF, 572 KB

dutch, 1980

73

The metabolism of pentachlorobenzene by rat liver microsomes: The nature of the reactive intermediates formed

C. den Besten, M.M.C.G. Peters, P.J. van Bladeren

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 497 KB

english, 1989

74

The use of in vitro metabolic parameters and physiologically based pharmacokinetic (PBPK) modeling to explore the risk assessment of trichloroethylene

Erna M. Hissink, Jan J.P. Bogaards, Andreas P. Freidig, Jan N.M. Commandeur, Nico P.E. Vermeulen, Peter J. van Bladeren

Journal:

Environmental Toxicology and Pharmacology

Year:

2002

Language:

english

File:

PDF, 251 KB

english, 2002

75

P3G202 - Use of intestinal epithelial cell as a model to screen absorption enhancement

E. Duizer, P.J. van Bladeren, J.P. Groten

Journal:

Toxicology Letters

Year:

1998

Language:

english

File:

PDF, 265 KB

english, 1998

76

Effect of glutathione and cysteine on apical and basolateral uptake and toxicity of CdCl2 in kidney cells (LLC-PK1)

Bruggeman, I.M., Temmink, J.H.M., van Bladeren, P.J.

Journal:

Toxicology in Vitro

Year:

1992

Language:

english

File:

PDF, 524 KB

english, 1992

77

Quantitative studies of the metabolism of furazolidone by rat liver microsomes

Vroomen, L.H.M., van Ommen, B., van Bladeren, P.J.

Journal:

Toxicology in Vitro

Year:

1987

Language:

english

File:

PDF, 659 KB

english, 1987

78

Quantitative comparison between in vivo DNA adduct formation from exposure to selected DNA-reactive carcinogens, natural background levels of DNA adduct formation and tumour incidence in rodent bioassays

Paini, A., Scholz, G., Marin-Kuan, M., Schilter, B., O'Brien, J., van Bladeren, P. J., Rietjens, I. M. C. M.

Journal:

Year:

2011

Language:

english

File:

PDF, 381 KB

english, 2011

79

Evaluation of Human Interindividual Variation in Bioactivation of Estragole Using Physiologically Based Biokinetic Modeling

Punt, A., Jeurissen, S. M., Boersma, M. G., Delatour, T., Scholz, G., Schilter, B., van Bladeren, P. J., Rietjens, I. M. C. M.

Journal:

Toxicological Sciences

Year:

2010

Language:

english

File:

PDF, 406 KB

english, 2010

80

The effect of co-administered flavonoids on the metabolism of hesperetin and the disposition of its metabolites in Caco-2 cell monolayers

Walter Brand, Beatriz Padilla, Peter J. van Bladeren, Gary Williamson, Ivonne M. C. M. Rietjens

Journal:

Molecular Nutrition & Food Research

Year:

2010

Language:

english

File:

PDF, 303 KB

english, 2010

81

Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2

Heleen M. Wortelboer, Michiel G.J. Balvers, Mustafa Usta, Peter J. van Bladeren, Nicole H.P. Cnubben

Journal:

Environmental Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 405 KB

english, 2008

82

Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment

V.J. Feron, H.P. Til, Flora de Vrijer, R.A. Woutersen, F.R. Cassee, P.J. van Bladeren

Journal:

Mutation Research/Genetic Toxicology

Year:

1991

Language:

english

File:

PDF, 1.98 MB

english, 1991

83

Glutathione conjugation; mechanisms and biological significance: Edited by Helmut Sies and Brian Ketterer, Academic Press, 1988. £47.50/US$95.00 (480 pages) ISBN 0 12 642755 0

Peter J.van Bladeren

Journal:

Trends in Pharmacological Sciences

Year:

1989

Language:

english

File:

PDF, 320 KB

english, 1989

84

Biotransformation of 1,2-dihydronaphthalene and 1,2-dihydroanthracene by rat liver microsomes and purified cytochromes P-450. Formation of arene hydrates of naphthalene and anthracene

Boyd, Derek R., Sharma, Narain D., Agarwal, Rajiv, McMordie, R. Austin S., Bessems, Jos G. M., van Ommen, Ben, van Bladeren, Peter J.

Journal:

Chemical Research in Toxicology

Year:

1993

Language:

english

File:

PDF, 736 KB

english, 1993

85

Trichloroethylene Risk Assessment: Relevance of Interindividual Differences

Vermeulen, N.P.E., Bladeren, P.J. van

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2001

Language:

english

File:

PDF, 343 KB

english, 2001

86

ChemInform Abstract: FACILE SYNTHESIS OF K-REGION ARENE OXIDES

VAN BLADEREN, P. J., JERINA, D. M.

Journal:

Chemischer Informationsdienst

Year:

1984

File:

PDF, 203 KB

1984

87

Cytochrome P450 catalyzed metabolism of 1,2-dibromoethane in liver microsomes of differentially induced rats

Lars W. Wormhoudt, Jan H.T.M. Ploemen, Jan N.M. Commandeur, Ben van^Ommen, Peter J. van Bladeren, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1996

Language:

english

File:

PDF, 903 KB

english, 1996

88

Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds

Heleen M. Wortelboer, Mustafa Usta, Jelmer J. van Zanden, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 456 KB

english, 2005

89

Reversible interaction of a reactive intermediate derived from furazolidone with glutathione and protein

Louis H.M. Vroomen, Marcel C.J. Berghmans, John P. Groten, Jan H. Koeman, Peter J. van Bladeren

Journal:

Toxicology and Applied Pharmacology

Year:

1988

Language:

english

File:

PDF, 659 KB

english, 1988

90

Isoenzyme selective irreversible inhibition of rat and human glutathione S-transferases by ethacrynic acid and two brominated derivatives

Jan H.T.M. Ploemen, Jan J.P. Bogaards, Gerrit A. Veldink, Ben van Ommen, Dilian H.M. Jansen, Peter J. van Bladeren

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 830 KB

english, 1993

91

The influence of disulfiram and other inhibitors of oxidative metabolism on the formation of 2-hydroxyethyl-mercapturic acid from 1,2-dibromoethane by the rat

P.J. van Bladeren, J.J. Hoogeterp, D.D. Breimer, A. van der Gen

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 573 KB

english, 1981

92

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1

Raymond Evers, Nicole H.P Cnubben, Jan Wijnholds, Liesbeth van Deemter, Peter J van Bladeren, Piet Borst

Journal:

Year:

1997

Language:

english

File:

PDF, 814 KB

english, 1997

93

Physiologically Based Biokinetic (PBBK) Model for Safrole Bioactivation and Detoxification in Rats

Martati, E., Boersma, M. G., Spenkelink, A., Khadka, D. B., Punt, A., Vervoort, J., van Bladeren, P. J., Rietjens, I. M. C. M.

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 2.16 MB

english, 2011

94

Cytotoxicity of nephrotoxic glutathione-conjugated halohydroquinones

Mertens, J.J.W.M., Sterck, J.G.H., Lau, S.S., Monks, T.J., van Bladeren, P.J., Temmink, J.H.M.

Journal:

Toxicology Letters

Year:

1990

Language:

english

File:

PDF, 182 KB

english, 1990

95

Association between Consumption of Cruciferous Vegetables and Condiments and Excretion in Urine of Isothiocyanate Mercapturic Acids

Vermeulen, Martijn, van den Berg, Robin, Freidig, Andreas P., van Bladeren, Peter J., Vaes, Wouter H. J.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

96

Dose-dependent kinetics and metabolism of 1,2-dichlorobenzene in rat: effect of pretreatment with phenobarbital

Hissink, A. M., Van Ommen, B., Van Bladeren, P. J.

Journal:

Year:

1996

Language:

english

File:

PDF, 5.10 MB

english, 1996

97

Glutathione S-transferases in relation to their role in the biotransformation of xenobiotics

Ria M.E. Vos, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Year:

1990

Language:

english

File:

PDF, 1.44 MB

english, 1990

98

Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin

Jelmer J. van Zanden, Omar Ben Hamman, Marlou L.P.S. van Iersel, Sjef Boeren, Nicole H.P. Cnubben, Mario Lo Bello, Jacques Vervoort, Peter J. van Bladeren, Ivonne M.C.M. Rietjens

Journal:

Chemico-Biological Interactions

Year:

2003

Language:

english

File:

PDF, 268 KB

english, 2003

99

Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate

Jan H.T.M. Ploemen, Ben van Ommen, Peter J. van Bladeren

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 568 KB

english, 1990

100

Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

P.J. van Bladeren, A. van der Gen, D.D. Breimer, G.R. Mohn

Journal:

Biochemical Pharmacology

Year:

1979

Language:

english

File:

PDF, 265 KB

english, 1979

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