Development of an Efficient and Practical Route for the Multikilogram Manufacture of Ethyl 5-Cyano-2-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate and Ethyl 6-Chloro-5-cyano-2-methylnicotinate, Key Intermediates in the Preparation of P2Y12 Antagonists
Bell, Stephen J., McIntyre, Steve, Garcia, Conchita F., Kitson, Sean L, Therkelsen, Frans, Andersen, Søren M, Zetterberg, Fredrik, Aurell, Carl-Johan, Bollmark, Martin, Ehrl, RobertVolume:
16
Language:
english
Pages:
5
Journal:
Organic Process Research & Development
DOI:
10.1021/op200368m
Date:
May, 2012
File:
PDF, 301 KB
english, 2012