An Efficient, Direct Bis-ortho-chlorination of 4-(Difluoromethoxy)aniline and Its Application to the Synthesis of BMS-665053, a Potent and Selective Pyrazinone-Containing Corticotropin-Releasing Factor-1 Receptor Antagonist
Li, Jianqing, Smith, Daniel, Krishnananthan, Subramaniam, Hartz, Richard A., Dasgupta, Bireshwar, Ahuja, Vijay, Schmitz, William D., Bronson, Joanne J., Mathur, Arvind, Barrish, Joel C., Chen, Bang-ChVolume:
16
Language:
english
Journal:
Organic Process Research & Development
DOI:
10.1021/op2003198
Date:
January, 2012
File:
PDF, 303 KB
english, 2012
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