Discovery of 2,6–difluorobenzyl ether series of phenyl...

Bioorganic & Medicinal Chemistry Letters 2020 / 10 Vol. 30; Iss. 19

Discovery of 2,6–difluorobenzyl ether series of phenyl ((R)–3–phenylpyrrolidin–3–yl)sulfones as surprisingly potent, selective and orally bioavailable RORγt inverse agonists

Duan, James J.-W., Jiang, Bin, Lu, Zhonghui, Stachura, Sylwia, Weigelt, Carolyn A., Sack, John S., Khan, Javed, Ruzanov, Max, Wu, Dauh–Rurng, Yarde, Melissa, Shen, Ding–Ren, Zhao, Qihong, Salterâ€
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Volume:
30
Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2020.127441
Date:
October, 2020
File:
PDF, 2.25 MB
2020
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