Vacuolar-type H+-ATPase inhibitory activity of synthetic...

Vacuolar-type H+-ATPase inhibitory activity of synthetic analogues of the concanamycins: Is the hydrogen bond network involving the lactone carbonyl, the hemiacetal hydroxy group, and the C-19 hydroxy group essential for the biological activity of the concanamycins?

Yuya Yoshimoto, Takaaki Jyojima, Tsuyoshi Arita, Minoru Ueda, Masaya Imoto, Shuichi Matsumura, Kazunobu Toshima
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Volume:
12
Year:
2002
Language:
english
Pages:
4
DOI:
10.1016/s0960-894x(02)00806-5
File:
PDF, 183 KB
english, 2002
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