Volume 26; Issue 3

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Antiviral Research
Volume 26; Issue 3

Antiviral Research

Volume 26; Issue 3

1

Interfering with HIV-1 replication by affecting cellular factors. HIV-1 inhibition by hydroxyurea

Franco Lori, Andrea Cara, Andrei G. Malykh, Daisy Sun, Julianna Lisziewicz, John Weintein, Robert C. Gallo

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 43 KB

english, 1995

2

Phosphorylation of HIV-1 matrix protein is necessary for nuclear targeting of viral preintegration complex: A.G. Bukrinskaya1, A. Ghorpade2, A.M. Ragland2, N.K. Heinzinger2, T.E. Smithgall3, R.E. Lewis3, M. Stevenson2, 1D.I. Ivanovsky Institute of Virology, Moscow, Russia; 2Department of Pathology and Microbiology, University of NE Medical Center, Omaha, NE; 3Eppley Institute for Research in Cancer and Allied Diseases, University of NE Medical Center, Omaha, NE

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 66 KB

english, 1995

3

Phosphonate derivatives of six membered-ring nucleosides: Synthesis and antiviral evaluation: M.J. Pérez-Pérez#, J. Balzarini§, J. Rozenski#, E. De Clercq§ and P. Herdewijn#. #Medicinal Chemistry and §Experimental Chemotherapy, Rega Institute, B-3000 Leuven, Belgium

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 66 KB

english, 1995

4

Mode of action of SDZ NIM 811, a non-immunosuppressive Cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1)

B. Rosenwirth, A. Billich, A. Steinkasserer, F. Hammerschmid, P. Peichl

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 74 KB

english, 1995

5

Cyclosporin A modulation of primary simian immunodeficiency virus (SIV) infection in rhesus monkeys: L.N. Martin1, M. Murphey-Corb1, P. Mack1, G.B. Baskin1, G. Pantaleo2, M. Vaccarezza2, C.H. Fox3, and A.S. Fauci2. 1Tulane Regional Primate Research Center, Covington, LA, 2Laboratory of Immunoregulation, NIAID/NIH, Bethesda, MD, 3Molecular Histology, Inc., Gaithersburg, MD

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 74 KB

english, 1995

6

Ingenol derivatives, ingredient of ‘Kansui’, are highly potent inhibitor of HIV

M. Fujiwara, K. Ijichi, K. Konno, T. Yokota, K. Tokuhisa, K. Katsuura, D. Uemura, S. Shigeta, M. Baba

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

7

1592U89 succinate — a potent, selective anti-HIV carbocyclic nucleoside: S.M. Daluge, S.S. Good, M.B. Faletto, M.T. Martin, W.H. Miller, D.R. Averett, M.H. St. Clair, L.R. Boone, M. Tisdale1, and J.E. Reardon. Wellcome Research Laboratories, Research Triangle Park, NC 27709, USA, and 1Beckenham, UK

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 79 KB

english, 1995

8

1592U89 succinate — preclinical toxicological and disposition studies and preliminary clinical pharmacokinetics: S.S. Good, S.M. Daluge, S.V. Ching, K.M. Ayers, W.B. Mahony, M.B. Faletto, B.A. Domin, B.S. Owens, R.E. Dornsife, J.A. McDowell, S.W. LaFon, and W.T. Symonds. Wellcome Research Laboratories, Research Triangle Park, NC 27709, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

9

A randomized, double-blind, placebo-controlled phase I/II evaluation of 9-[2-(bispivaloyloxy-methyl) phosphonyl-methoxy]adenine (bis-POM PMEA), an orally bioavailable prodrug of the anti-HIV nucleotide, PMEA: PA Barditch-Crovo, J Toole, H Burgee, M Wachsman, D Ebeling, KC Cundy, HS Jaffe, PS Lietman. The Johns Hopkins University, Baltimore MD and Gilead Sciences, Inc., Foster City, CA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 82 KB

english, 1995

10

A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo: R. Déziel, N. Moss, M. Liuzzi, P. Beaulieu, A.-M. Bonneau, C. Bousquet, M. Llinas-Brunet, J. G. Chafouleas, J.-S. Duceppe, J.-M. Ferland, M. Garneau, J. Gauthier, E. Ghiro, S. Goulet, L. Grenier, J. Jaramillo, R.L. Krogsrud, L. Lagacé, R. McCollum, S. Nawoot, R. Plante, D. Wernic, and Y. Guindon. Bio-Méga/Boehringer Ingelheim Research Inc., 2100 Cunard Street, Laval, Québec, Canada, H7S 2G5

Journal:

Antiviral Research

Year:

1995

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english

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PDF, 38 KB

english, 1995

11

Resistance of HSV-1 to peptidomimetic ribonucleotide reductase inhibitors: Selection and characterization of mutant isolates: A.M. Bonneau*, P. Kibler, P. White, C. Bousquet, N. Dansereau and M. Cordingley. Bio-Méga Boehringer Ingelheim Research, Inc., Canada

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 62 KB

english, 1995

12

Antiviral activity of 2-phosphonomethoxyalkyl derivatives of N6-substituted 6-aminopurines

A. Holý, R. Snoeck, G. Andrei, J. Balzarim, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 62 KB

english, 1995

13

Ultratrace determination of penciclovir-triphosphate (PCV-TP) in a herpes simplex virus type 1 (HSV-1)-infected cell line using flow-injection electrospray ionization tandem mass spectrometry (MS-MS): E.M. Smyrnis, R. Burton, F. Abbott, R.A. Wall, and S.L. Sacks. Viridae Clinical Sciences Inc. and University of British Columbia, Vancouver, Canada

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

14

Famciclovir and valaciclovir treatment during acute HSV-1 infection of mice have markedly different effects on subsequent virus reaction from ganglia: HJ Field & AM Thackray, University of Cambridge, Madingley Road, Cambridge, CB3 OES, U.K.

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

15

Adjuvant effect of imiquimod when combined with HSV glycoprotein vaccine in guinea pigs with recurrent HSV-2 genital herpes: C.J. Harrison*, R.L. Miller and D.I. Bernstein. Creighton Univ. and Univ. of Neb. M.D., Omaha, NE, 3M Pharmaceuticals, St. Paul, MN, and J.N. Gamble Inst. Med. Res., Cincinnati, OH

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 70 KB

english, 1995

16

DNA vaccine protects mice from vaginitis and death due to herpes simplex virus type 2 (HSV-2): JD Kriesel, JW Ricigliano, SL Spruance, and BA Araneo. University of Utah and Paradigm Biosciences, Inc., Salt Lake City, Utah, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 70 KB

english, 1995

17

Valtrex* (Valaciclovir, VACV) for the treatment of recurrent genital herpes: S. Safrin, San Francisco General Hospital, California, USA for the International Valaciclovir HSV Study Group

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 40 KB

english, 1995

18

New classes of reagents that attack conserved and chemically reactive zinc fingers in retroviral nucleocapsid proteins: A strategy for rational drug design: W. G. Rice, C. A. Schaeffer, J. A. Turpin, L. Coreff†, R. C. Sowder II†, B. Kane†, J. Bader, L. O. Arthur†, and L. E. Hertterson†: Laboratory of Antiviral Drug Mechanisms and †AIDS Vaccine Program PRI/DynCorp, NCI-FCRDC, Frederick, MD, USA and Developmental Therapeutics Program, National Cancer Institute, Bettesda, MD USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 58 KB

english, 1995

19

Anti-HIV activities of new PETT compounds in cell cultures

B. Öberg, C. Åhgren, B. Classon, P. Engelhardt, M. Högberg, N.-G. Johansson, J. Kangasmetsä, P. Lind, C. Lopez, S. Mauldin, J.M. Morin jr, J. Munroe, R. Noréen, C. Rydergåd, C. Sahlberg, R.J. Ternansk

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

20

Novel mutations in the reverse transcriptase of HIV-1 reduce susceptibility to phosphonoformate in laboratory and clinical isolates: J. Mellors1, H. Bazmi1, R. Schinazi2, B. Roy3, Y. Hsiov3, E. Arnold3, J. Weir4, D. Mayers4. 1University of Pittsburgh/VAMC, Pittsburgh, PA, 2Emory University/VAMC, Decatur, GA, 3Rutgers University/CAMB, Piscataway, NJ, 4Military Medicine Consortium for Applied Retroviral Research, Rockville, MD, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 73 KB

english, 1995

21

Thiocarboxanilide derivatives synergistically suppress the breakthrough of human immunodeficiency virus type I (HIV-1) in CEM cell cultures when used in combination with TSAO derivatives

J. Balzarini, M.-J. Pérez-Pérez, S. Velázquez, A. San-Félix, M.-J. Camarasa, E. De Clercq, A. Karlsson

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 71 KB

english, 1995

22

DMP450, a new cyclic urea inhibitor of HIV protease with potent in vitro antiviral activity

D.L. Winslow, C.D. Reid, S. Garber, P. Aldrich, H. Scarnati, E. Anton, M.J. Otto

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 71 KB

english, 1995

23

In vivo selection by monotherapy of HIV-1 variants resistant to multiple protease inhibitors: J.H. Condra, W.A. Schleif, O.M. Blahy, L.J. Gabryelski, D.J. Graham, J.C. Quintero, A. Rhodes, H.L. Robbins, E. Roth, M. Shivaprakash, D.L. Titus, T. Yang, H. Teppler†, K.E. Squirest††, P.J. Deutsch* and E.A. Emini. Departments of Antiviral Research and *Clinical Pharmacology, Merck Research Laboratories, West Point, PA 19486 USA; †Division of Infectious Diseases, Thomas Jefferson University, Philadelphia, PA 19107 USA, and ††Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 85 KB

english, 1995

24

Antiviral agents reduce viral load and delay the detection of infected cells in vivo in the HIV-infected Hu-PBMC SCID mouse model: Michael A. Ussery1, Dennis D. Broud1, Owen L. Wood1, Steven C. Kunder1, Paul L. Black1, Peter J. Dailey2, Judith C. Wilber2, Limei Yang3, Michael Piatek, Jr.3, and Jeffery D. Lifson3. 1FDA, Rockville, MD 20857; 2Chiron Corp., Emeryville, CA 94668; and 3Genelabs Technologies, Inc, Redwood City, CA 94063

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 85 KB

english, 1995

25

Nucleoside anti-HIV efficacy in the xenotransplanted nude mouse model: B.M. Welsh, S.W. Belzer, and N.T. Wetherall. ViroMed Laboratories, Inc., Minneapolis, MN, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 47 KB

english, 1995

26

Multiple drug effect analyses with confidence intervals for the evaluation of interactions of combined antiviral agents against hepatitis B virus: R.F. Schinazi,1* B. E. Korba,2 M. Belen'kii,1 C. K Chu,3 and J. D. Gangemi.4 Dept. of Pediatrics, VA Medical Center/Emory University, Decatur, GA 30033;1 DMVI, Georgetown University, Rockville MD 20852,2 Dept. of Medicinal Chem., College of Pharmacy, University Georgia, Athens, GA 30602,3 and Greenville Hospital System, Clemson University, Clemson, SC 29634,4 USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 40 KB

english, 1995

27

Cellular pharmacology of β - L - dideoxycytidine, β - L - 2′, 3′ dideoxy - 5 - fluorocytidine, and β - D - 2′, 3′ dideoxy - 5 - fluorocytidine: L.T. Martin1, R.F. Schinazi2, G. Gosselin3, J.-L. Imbach3, and J.-P. Sommadossi1. University of Alabama at Birmingham, Birminghmn, AL 35294 USA;1 VA Medical Center/Emory University, Decatur, GA 30033 USA;2 University of Montpellier II, 34095 Montpellier, France.3

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 88 KB

english, 1995

28

Selective liver targeting of a derivatized antiviral nucleoside analogue by recombinant chylomicrons: P.C.N. Rensen, M.C.M. van Dijk, E.C. Havenaar, M.K. Bijsterbosch, J.K. Kruijt, and T.J.C. van Berkel. Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, University of Leiden, Sylvius Laboratories, P.O. Box 9503, 2300 RA Leiden, The Netherlands

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 88 KB

english, 1995

29

Penciclovir: A novel nucleoside analogue with potent activity against duck hepatitis B virus in vivo: S Locarnini, E Lin, C Luscombe, P Edwards, D Anderson, T Shaw. Victorian Infectious Diseases Reference Laboratory and Macfarlane Burnet Centre for Medical Research, Fairfield Hospital, Fairfield, Victoria 3078, Australia

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 67 KB

english, 1995

30

Inhibition of HPV-11 gene expression with chimeric methylphosphonate oligomers

C. Giachetti, J. Marich, R. Salunga, J. Jaeger, B. Selling, B Tseng

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 67 KB

english, 1995

31

SV40 DNA hybridization assay: Use as a primary cell-based screen for antiviral inhibitors of human papovaviruses: J.A. Barnes, W.C. Phelps. Burroughs Wellcome Co., Research Triangle Park, N.C. U.S.A.

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 89 KB

english, 1995

32

The SCID-Ra model for evaluation of inhibitors of papillomaviruses

D.C. Lobe, C.S. Dunn, W.C. Phelps

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 89 KB

english, 1995

33

Multi-center safety and efficacy trial evaluating three times per week application of 1% and 5% topical imiquimod for the treatment of genital/perianal warts: L. Edwards, Carolinas Medical Center, Charlotte, NC, USA; A. Ferenczy, Jewish General Hospital, Montreal, Quebec, Canada; L. Eron, Infectious Disease Physicians, Annandale, VA, USA; D. Baker, HSC SUNY, Stony Brook, NY, USA; T. Fox, K. Gayoso, A. Hougham, M. Owens, 3M Pharmaceuticals, St. Paul, MN, USA; and the Topical Imiquimod HPV Study Group

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 43 KB

english, 1995

34

Inhibition of HIV- and HBV-virus replication by 2,6-disubstituted purine 2′, 3′-dideoxynucleosides: G. W. Koszalka, C. L. Burns, M. St. Clair, L. Frick, C. U. Lambe, M. T. Paff, D. J. Nelson, B. Korba+, K. Ayers and T. A. Krenitsky, Burroughs Wellcome Co., 3030 Cornwallis Road, Research Triangle Park, NC 27709; +Georgetown University, Division of Molecular Biology and Virology, 5640 Fishers Lane Rockville, MD 20852

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 49 KB

english, 1995

35

Stereospecific synthesis and antiviral evaluation of purine nucleoside L-enantiomers: β-L-Ara-A, 3′-deoxy-β-L-Ribo-A and β-L-Lyxo-A

J.-L. Imbach, V. Boudou, M.-C. Bergogne, G. Gosselin

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 52 KB

english, 1995

36

The synthesis and biological evaluation of phosphate triester alkyl lysophospholipids (ALPs) as potential antineoplastic and anti-HIV agents

Y. Wang, C. McGuigan, AJ. Hay, N. Mahmood, J. Balzarini, E. De Clercq, PA. Riley

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 52 KB

english, 1995

37

Enzymatic synthesis of 3′-azido-3′-deoxy-5′-O-(1,2-dihexadecanoyl-3-sn-phosphatidyl)thymidine involving commercially available phospholipase D type VII

B.E. Reitter, J.L. Rideout, M.R. Almond

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 60 KB

english, 1995

38

5-halo-6-alkoxy(or azido)-5,6-dihydro-3′-azido-3′-deoxythymidine diastereomers as potential produgs of 3′-azido-3′-deoxythymidine (AZT): E. E. Knaus*1, L. I. Wiebe1, L. Wang1, R. Kumar1, K. W. Morin1, K. G. Todd2 and G. B. Baker2. 1Faculty of Pharmacy and 2Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada T6G 2N8

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 60 KB

english, 1995

39

Chemoenzymatic synthesis of carbocyclic nucleotide mimics possessing potent activity against HIV-reverse transcriptase

C.J. Clements, S.M. Roberts, V. Merlo

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 54 KB

english, 1995

40

A new synthesis of 2′-deoxypyrimidine nucleosides involving sodium cyanoborohydride

M.R. Almond, B.E. Reitter, J.L. Rideout

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 54 KB

english, 1995

41

4(S)(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol: Synthesis, enzymology and anti-HIV studies

V. Nair, J.L. Rideout, M.H. St. Clair, H.C. Krasny, J.E. Reardon, R. Dornsife, T. Spector

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 74 KB

english, 1995

42

Structure-activity relationships studies in TSAO-T derivatives modified at the 2′- and 5′- positions of the sugar moiety

S.T. Ingate, M.J. Camarasa, E. De Clercq, J. Balzarini

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 74 KB

english, 1995

43

The synthesis of novel phospholipids with potential antineoplastic and antiviral activity

MS. Wilson, C. McGuigan, A.J. Hay, N. Mahmood, J. Balzarini, E. De Clercq, A. Postle, PA. Riley

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 51 KB

english, 1995

44

On the bioisosteric potential of the pyridazine core in the systematic structural modification of antiviral agents

G. Heinisch, J. Easmon, B. Matuszczak

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 51 KB

english, 1995

45

Preparation and anti-viral activity of oligoribonucleotides containing 5-fluorouridine: W. H. Gmeiner, P. Sahasrabudhe, N. Schulte, P.L. Iversen, S. Rhode Contribution from the Eppley Cancer Institute, University of Nebraska Medical Center, Omaha, NE USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 66 KB

english, 1995

46

Preparation of enantiomerically pure branched DNA for shape specific binding of RNA hairpin loops: W.H. Gmeiner1, Yin Zhong1, Richard T. Pon2 Contribution from the 1Eppley Cancer Institute University of Nebraska Medical Center and the 2Regional DNA Synthesis Laboratory, University of Calgary

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 66 KB

english, 1995

47

Development of a non-hazardous biological assay system for the screening of anti-HIV compounds

R. Kiser, S.T. Makovsky, J.P. Bader, H.K. Lyerly, B.R. Cullen, D.J. Clanton

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 69 KB

english, 1995

48

Fluorometric measurement of reverse transcriptase activity with 4′,6-diamidino-2-phenylindole (DAPI): SJ Chavan and HJ Prochaska, Molecular Pharmacology & Therapeutics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 69 KB

english, 1995

49

Heat shock induces HIV-1 replication in chronically infected promyelocyte cell line OM10.1: Implication of a new anti-HIV-1 assay in vitro

K. Hashimoto, M. Baba, K. Gohnai, M. Sato, S. Shigeta

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 65 KB

english, 1995

50

High throughput screening for small molecule inhibitors of the HIV- Rev-RRE interaction

J.E. Arenas, K.T. Lam, J. Lillie

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 65 KB

english, 1995

51

Thiadiazole derivatives as highly potent inhibitor of human immunodeficiency virus type 1 (HIV-1)

M. Fujiwara, K. Ijichi, K. Konno, T. Yokota, Y. Hanasaki, H. Watanabe, K. Katsuura, S. Shirakawa, H. Takayama, S. Sakai, S. Shigeta, M. Baba

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 76 KB

english, 1995

52

QSAR study of nucleoside analogs with anti-HIV activity using molecular similarity analysis and structure-activity maps

C.C. Tsai, P.J. Durand, K.J. Taylor, J.W. Baker

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 76 KB

english, 1995

53

Intracellular activation and cytotoxicity of combinations of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine: S. Palmer and S. Cox. Virology Dept, Swedish Institute for Infectious Disease Control, Karolinska Institute, 10521 Stockholm, Sweden

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 74 KB

english, 1995

54

Activity of AZT and ddI when used in combination with other mechanistically diverse inhibitors of HIV replication: Robert W. Buckheit, Jr. and Julie D. Russell, Southern Research Institute-Frederick Research Center, Frederick, MD USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 74 KB

english, 1995

55

Use of drug combinations for selection of human immunodeficiency virus type I (HIV-1) variants with decreased sensitivity to hydroxyethylurea isostere containing protease inhibitors in vitro

M.L. Smidt, K.E. Potts, S.P. Tucker, T.R. Stiebel Jr., W.C. Stallings Jr., M. Clare, M.L. Bryant

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 65 KB

english, 1995

56

Combined antiviral effect of flavonoid and acyclovir

Ilona Béládi, Ilona Mucsi, Anneliese Veckenstedt, Rozália Pusztai, Zsófia Gyulai

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 65 KB

english, 1995

57

[AZT]-[TSAO-T] and [AZT]-[HEPT] heterodimers as potential bi-functional inhibitors of HIV-1 reverse transcriptase, synthesis, structural assignment and Anti-HIV activity

M.J. Camarasa, S. Velázquez, R. Alvarez, A. San-Félix, M.L. Jimeno, E. De Clercq, J. Balzarini

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 69 KB

english, 1995

58

Optimization of antiviral and kinetic properties of PETT compounds, a class of potent non-nucleoside HIV-RT inhibitors

N.-G. Johansson, B. Classon, P. Engelhardt, M. Högberg, J. Kangasmetä, P. Lind, C. Lopez, S. Mauldin, J.M. Morin jr, J. Munroe, R. Noréen, B. Öberg, C. Sahlberg, R.J. Ternansky, L. Vrang, H. Zhang

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 69 KB

english, 1995

59

Synthesis and structure-activity relationship of thiadiazole derivatives, novel nonnucleoside inhibitors of HIV-1

T. Yokota, M. Fujiwara, K. Ijichi, K. Konno, Y. Hanasaki, H. Watanabe, K. Katsuura, S. Shirakawa, H. Takayama, S. Sakai, S. Shigeta, M. Baba

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 75 KB

english, 1995

60

Mechanism of anti-human immunodeficiency virus (HIV) action of selected ATA-polymer analogues

D. Reymen, M. Cushman, P. Wang, M. Witvrouw, J. Esté, J. Neyts, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 75 KB

english, 1995

61

3′ → 5′ and 5′ → 5′ uridine-AZT phosphodiester dimers: Synthesis and in vitro anti-HIV activities

J.-L. Imbach, C. Pierra, C. Perigaud, A. Faraj, J.-P. Sommadossi, A.-M. Aubertin, G. Gosselin

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 63 KB

english, 1995

62

Synthesis, anti-human immunodeficiency virus activities, cytotoxicities, and decomposition pathways of the bis(SATE)phosphotriester derivatives of AZT

J.-L. Imbach, I. Lefebvre, J.-L. Girardet, A. Pompon, M.-Y. Xie, J.-P. Sommadossi, A.-M. Aubertin, C. Perigaud, G. Gosselin

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 63 KB

english, 1995

63

Inhibition of human immunodeficiency virus envelope glycoprotein-mediated cell fusion by synthetic phospholipid analogs

L. Kucera, J. Thompson, N. Iyer, R. Poduval, S. Morris-Natschke, K. Ishaq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 64 KB

english, 1995

64

Characterization of siamycin I, an HIV fusion inhibitor

P.-F. Lin, H. Samanta, C.M. Bechtold, C. Deminie, M. Alam, K. Riccardi, R.E. Rose, A.K. Patick, R. White, R.J. Colonno

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 64 KB

english, 1995

65

Structure-activity relationship studies for various oxathiin carboxanilide derivatives modified in the oxathiin moiety against wild-type and mutant human immunodeficiency virus type 1 strains

J. Balzarini, W.G. Brouwer, D.C. Dao, E.E. Felauer, W.A. Harrison, E. De Clercq, A. Karlsson

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

66

Pyrryl-aryl-sulphones: synthesis and anti-HIV activity

A. De Montis, M. Doa, A.G. Loi, M. Artico, R. Silvestri, G. Stefancich, S. Massa, P La Colla

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

67

Effect of specific amino acid changes on the anti-HIV activity of NNRTIs: Confirmation of NNRTI-resistant virus subgrouping and selection of compounds for combination therapy: R.W. Buckheit, Jr., V. Fliakas-Boltz and L.A. Pallansch. Southern Research Institute-Frederick Research Center, Frederick, MD USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 89 KB

english, 1995

68

Unique purine crossover activation pathway for the potent anti-HIV agent 1592U89

M.B. Faletto, W.H. Miller, E.P. Garvey, M.H. St. Clair, R.J. Hazen, S.M. Daluge, S.S. Good

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 89 KB

english, 1995

69

Characterization of the anti-HIV-1 activity of DABOs

A.G. Loi, E. Tramontano, A. De Montis, M.E. Marongiu, M. Artico, S. Massa, A. Mai, P. La Colla

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 68 KB

english, 1995

70

Anti-HIV activity of bovine seminal RNase

P. La Colla, D. Lichino, A.G. Loi, G. D'Alessio

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 68 KB

english, 1995

71

Creatine phosphate inhibits the replication of HIV in macrophages

L.J. Hansen, R. Kaddurah-Daouk

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

72

Zidovudine (AZT) treatment of liver cells causes accumulation of intracellular lipid droplets, and phosphorylated zidovudine intracellularly increases lactate in medium, and inhibits mitochondrial DNA polymerase-γ

E. Lewis, E.S. Levine, B. Stretcher

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

73

AZT metabolism and toxicity: Application of 5-azido-3′-azido-2′,3′-dideoxyuridine monophosphate, a photoaffinity analog of AZT-monophosphate: R. R. Drake, L. J. Underwood, R. Jones, E. Battaglia^, F. Mao, T. M Rechtin, A. Cantu#, S. Anderson#, A. Radominska^, and M. P. Moyer# Depts of Biochemistry and Medicine^, U.A.M.S., Little Rock, AR 72205, Dept. of Surgery#, U.T.H.S.C., San Antonio, TX 78284

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

74

In vitro potency of inhibition by antiviral drugs of hematopoietic progenitor colony formation correlates with exposure at hemotoxic levels in HIV positive humans

R.E. Dornsife, D.R. Averett

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

75

Cationic liposome-mediated delivery of anti-HIV-1 ribozyme to chronically infected cells

K. Konopka, J.J. Rossi, P. Felgner, N. Düzgünes

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 86 KB

english, 1995

76

Metabolism of the carbocyclic analog of 2′-deoxyguanosine (CdG) in human cells: Allan, P.W., W.B. Parker, G. Arnett, L.M. Rose, S.C. Shaddix, D.S. Shewach, I. Fourel, J.A. Secrist III, J.A. Montgomery, Y.F. Shealy and L.L. Bennett, Jr.; Southern Research Institute, Birmingham, AL; Fox Chase Cancer Center, Philadelphia, PA; and University of Michigan Cancer Center, Ann Arbor, MI

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 86 KB

english, 1995

77

Antiviral resistance to enantiomers of 2′,3′-dideoxycytidine analogues — Common threads: R. F. Schinazi,1* R. M. Lloyd, Jr.,1 A. McMillan,1 G. Gosselin,2, J.-L. Imbach,2 C.K. Chu,3, and J.-P. Sommadossi.4 VA Medical Center/Emory University, Decatur, GA 30033;1 University of Montpellier II, 34095 Montpellier, France,2 Dept. of Medicinal Chemistry, College of Pharmacy, University Georgia, Athens, GA 30602,3 and University of Alabama, Birmingham, AL 35294,4 USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

78

Kinetic analysis of human immunodeficiency virus type-1 reverse transcriptase with mutations at methionine 184 in the highly conserved YMDD region: JE Wilson1, B Caligan1, A Aulabaugh2, S McPherson3, JK Wakefield3, S Jablonski3, CD Morrow3, PA Furman2, and JE Reardon1. 1Division of Biochemistry and 2Division of Virology, Burroughs Wellcome Co., Research Triangle Park, NC, USA, and 3Department of Microbiology, University of Alabama at Birmingham, Birmingham, Al, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

79

Characterization of HIV-1 reverse transcriptase encoding mutations at the amino acid residues 161 and 208 involved in phosphonoformate resistance

E. Tramontano, G. Piras, E. Congeddu, J. Mellors, H. Bazmi, P. La Colla

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 86 KB

english, 1995

80

In vitro selection of HIV-1 resistance of ddI is not as efficient as for other antiretroviral drugs and yields virus which shows reduced cytophatic activity

F. Dianzani, G. Antonelli, D. Bellarosa, F. Bambacioni, E. Riva, A. Gentile, O. Turriziani

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 86 KB

english, 1995

81

3-dimensional structure studies of thiadiazole-derivatives for anti-HIV-1 RT activity

H. Nagano, K. Ijichi, Y. Matsumoto, M. Fujiwara, Y. Hanasaki, H. Watanabe, M. Katsuura, S. Shirakawa, H. Takayama, S. Sakai, S. Shigeta, K. Konno, M. Baba, M. Matsushima, T. Yokota

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

82

Characterization of a cellular line expressing a defect of thymidine kinase activity and displaying resistance to the antiviral activity of AZT

G. Antonelli, O. Turriziani, S. Strosselli, A. Verri, M. Cianfriglia, E. Riva, E. Simeoni, E. Dianzani

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

83

Kinetic analysis of the interaction of inhibitors with RMuLV and human immunodeficiency virus (HIV) reverse transcriptases (RTs): J.M. Cherrington1, S.J.W. Allen1, S.C. Kunder2, M.A. Ussery2 and M.S. Chen1. 1Gilead Sciences, Inc., Foster City, CA, 94404; 2FDA, Rockville, MD 20857

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 52 KB

english, 1995

84

Cloning, purification and biochemical characterization of HIV-2 reverse transcriptase (RT) and comparison with endogenous HIV-2 RT

G. Piras, E. Tramontano, M. Putzolu, R. Casula, P. La Colla

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 52 KB

english, 1995

85

Homology modeling and molecular dynamics simulation studies of a hypothetical HIV-1 DNA binding protein and potential E2-like target site in the HIV-1 LTR: Chandra S. Ramanathan, David E. Stewart and E. Will Taylor, Computational Center for Molecular Structure and Design and Department of Medicinal Chemistry, University of Georgia, Athens, GA 30602-2352

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 91 KB

english, 1995

86

Do some viruses encode selenoproteins? — Assessment of the theory in the light of current theoretical, experimental and clinical data: E. Will Taylor, C. S. Ramanathan, R. G. Nadimpalli & R. F. Schinazi, Dept. of Medicinal Chemistry. The University of Georgia, Athens, GA 30602, and Dept. of Pediatrics, Emory University and Veterans Administration Medical Centre, 1670 Claimont Road, Decatur, GA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 91 KB

english, 1995

87

Anti-retroviral activities of baicalin in vitro and in vivo: Ilongshan Chen, Xing-quan Zhang, Li Teng, Xiao-xian Wu, Yao-zeng Lu, Xiao-shan Tang, Xian-shu Yang, xu- guang Yan, Institute of Medical Biotechnology, Institute of Experimental, Chinese Academy of Medical Sciences, Beijing, 100050, China

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

88

Sequence within the HIV-1 LTR required for strand transfer by integrase in vitro

D.J. Hazuda, P.J. Felock, R.L. LaFemina, A.L. Wolfe

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 79 KB

english, 1995

89

A retrometabolic concept: The pronucleotide approach

J.-L. Imbach, C. Perigaud, G. Gosselin, G. Obert, A.-M. Aubertin, A. Kirn

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

90

Suppression of hematopoietic support function is associate with over-expression of IL-4 and TGFβ1 in LP-BM5 MuLV infected Stromal cell lines: Vincent S. Gallicchio, Kam-Fai Tse, Jennifer K. Morrow, Nedda K. Hughes. Hematology & Oncology Division, Departments of Internal Medicine, Clinical Sciences, Pathology and Toxicology, University of Kentucky Medical Center and Department of Veterans Affairs, Lexington, KY, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

91

Evaluation of anti-AIDS drugs in conventional mice implanted with a permeable membrane (hollow fiber) device containing human T cells infected with HIV: L. B. Allen1, D. C. Quenelle1, B. A. Taylor1, B. J. Bowdon1, K. Keith1, A.D. Brazier1, W. M. Shannon1 and K. E. Dunleavy2. 1Southern Research Institute, Birmingham, AL 35255. 2W.R. Grace & Co.-Conn., Lexington, MA 02173

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

92

In vitro and in vivo enhancement of ddI activity against rauscher murine leukemia virus (RMuLV) by ribavirin: D. C. Quenelle, L. B. Allen, L. Westbrook, B. A. Taylor, M. N. Prichard, A. D. Brazier, M. G. Hollingshead, and W. M. Shannon. Southern Research Institute, Birmingham, AL 35255

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

93

Antiretroviral activity of ribonucleotide reductase inhibitors hydroxyurea, didox and trimidox in the in vivo Rauscher murine leukemia virus (RMuLV) model: PL. Black1, S. C. Kunder1, B. E. Hall1, H.L. Elford2, and M. A. Ussery1. 1U.S.ED.A., Rockville, MD; 2Molecules for Health, Richmond, VA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 85 KB

english, 1995

94

Phosphorylation of 9-(2-phosphonyimethoxyethyl)adenine (PMEA) is greater in macrophages than in replicating lymphocytes and fibroblasts

E. Balestra, CF. Perno, J. Balzarini, S. Aquaro, G. Lazzarino, B. Tavazzi, D. Di Pierre, E. De Clercq, R. Calìo

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 85 KB

english, 1995

95

PMEA has immunomodulatory activity and inhibits reverse transcriptase in the Rauscher murine leukemia virus (RMuLV) model: S. C. Kunder, P. L. Black, B. E. Hall, and M. A. Ussery. U.S.F.D.A., Rockville, Md, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 76 KB

english, 1995

96

Antiviral efficacy in mice of oral bis(POM)-PMEA, the Bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine

L. Naesens, J. Neyts, J. Balzarini, N. Bischofberger, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 76 KB

english, 1995

97

n-docosanol prevents vaginal transmission of SIVmac251 in rhesus macaques

C.J. Miller, M.J. Gersten, R.C. Davis, D.H. Katz

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 85 KB

english, 1995

98

Pharmacokinetics in mice of bis(POM)-PMEA, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine

L. Naesens, J. Neytst, J. Balzarini, N. Bischofberger, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 85 KB

english, 1995

99

Study of human immunodeficiency virus resistance to the acyclic nucleoside phosphonate analogs: A. Fridland, P. Aduma, N. Sarkissian, R.V. Srinivas. Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38101

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 74 KB

english, 1995

100

Enzymatic phosphorylation of 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in drug sensitive and resistant cells: BL Robbins, MC Connelly, JJ Greenhaw, A. Fridland. Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38101

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 74 KB

english, 1995

101

Negatively charged human serum albumins: A novel class of polyanionic proteins with a potent anti-HIV-I activity

P.J. Swart, D.K.F. Meijer

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

102

Preparation and characterization of conjugates of (modified) human serum albumin liposomes: Drug carriers with an intrinsic anti-HIV activity

J.A.A.M. Kamps, P.J. Swart, H. Morselt, D.K.F. Meijer, G.L. Scherphof

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

103

Negatively charged human serum albumins: Inhibition of replication of primary HIV-1 isolates and biomolecular interaction with Gp120

M.E. Kuipers, P.J. Swart, M. Groenink, J.G. Huisman, H. Schuitemaker, D.K.F. Meijer

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

104

Pharmacokinetics and anti-HIV-1 efficacy of negatively charged human serum albumins in mice

M.E. Kuipers, P.J. Swart, M. Schutten, C. Smit, A.D.M.E. Osterhaus, D.K.F. Meijer

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

105

Further studies into the mechanism of interaction of negatively charged human serum albumins with the V3 loop of the HIV-1 envelope protein Gp120

M.E. Kuipers, J.G. Huisman, P.J. Swart, H. Schuitemaker, D.K.F. Meijer

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 83 KB

english, 1995

106

2′,-dideoxycytidine 5′-triphosphate analogs as substrate for human DNA polymerases: implication for the mechanism of toxicity

M. Kukhanova, S.H. Liu, C.K. Chu, Y.-C. Cheng

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 83 KB

english, 1995

107

Effect of protein binding on the pharmacodynamics of an HIV protease inhibitor: C. Flexner, D.D. Richman, M. Bryant, A. Karim, P. Yeramian, P. Meehan, R. Haubrich, M.F. Para, M.A. Fischl, and the AIDS Clinical Trials Group (ACTG) 282 Study Team. The Johns Hopkins University School of Medicine, Baltimore, Maryland, the University of California, San Diego, Searle R & D, Skokie, Illinois, Ohio State University, and the University of Miami, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

108

Red-blood cells mediated drug delivery to phagocytic cells as a selective therapeutic approach to infections by HIV and herpesviruses

CF. Perno, E Balestra, N. Santoro, G Lazzarino, D. Pozzi, B. Tavazzi, S. Aquaro, D. Di Pierro, S. Grimaldi, R. Calió

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

109

Membrane permeation characteristics of the structurally related anti-HIV agents 1592U89 and (−)-carbovir in human erythrocytes and human T-lymphoblastoid CD4+ CEM cells: T.P. Zimmerman, W.B. Mahony, B.A. Domin, and K.L. Prus. Wellcome Research Laboratories, Research Triangle Park, NC 27709, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 73 KB

english, 1995

110

Distribution to the brain, protein binding and physico-chemical properties of 5-substituted 3′-fluoro-uridine derivatives, studied by microdialysis

N Borg, X-X Zhou, L Ståhle

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 73 KB

english, 1995

111

Pharmacokinetics of 3′-fluoro-guanosine (FLG) in cynomolgus monkeys

N Borg, D Böttiger, X-X Zhou, N-G Johansson, B Öberg, L Ståhle

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

112

Competitive Elisa for D4T: Application to clinical pharmacology

R. Guedj, B. Ferrua, TT. Tran, JF. Quaranta, J. Kubar, C. Rotpin, R. Condom, M. Sinet, J. Durand

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

113

Zidovudine-uridine dimer and its hexadecyl ester: Synthesis, antiviral evaluation and pharmacokinetics: K.C. Agrawal, Q. Lu, M. Brakta, N. Bandera, S.R. Gogu and R.F. Garry. Depts. of Pharmacology and Microbiology & Imnunology, Tulane University School of Medicine, New Orleans, LA 70112, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 70 KB

english, 1995

114

Application of microdialysis to the study of antiviral drug pharmacokinetics in humans: validation of subcutaneous extracellular sampling of zidovudine

L Ståthle, E. Sandström

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 70 KB

english, 1995

115

One-month oral toxicity studies of a protease Inhibitor (ABT-987) in rats and Dogs: C. Yang, B. Gemzik, P. Ewing, M. Pratt, M. Friedman, P. Cusick, R. Krasula and R. Patterson. Drug Safety Evaluation, Abbott Laboratories, Abbott Park, IL 60064, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

116

ChemoimmunotherapyCI) by thiophenoyl urea(TUR) & Nonvirion antigen vaccine (NVA) for AIDS patients: A. Hollinshead, G. Wash, U. Med. Ctr., Washington D. C., USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 86 KB

english, 1995

117

Safe coadministration of famciclovir and zidovudine to HIV positive patients: S. Siederer1, S. Scott2, F. Rousseau3, S. Fowles1, P. Sparrow2, C. Lascoux3, V. Lehner3 and D. Serini3 SmithKline Beecham Pharmaceuticals, Welwyn1 and Harlow2, UK and Hopital Cochin, Paris. France3

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 72 KB

english, 1995

118

Anti-HIV agent 935U83 — Preliminary clinical assessment

S.M. Daluge, M.H. St. Clair, L. Wang, P.M. Savina, W. Spreen, J. Yeo, B.A. Larder, N. Parry, D.J.M. Purifoy, T.A. Krenitsky

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

119

L-FMAU, a novel anti-HBV and anti-EBV agent: Chu, C.K.1, Ma, T.W.1, Shanmuganathan, K.1, Wright, J.D.1, Boudinot, F.D.1, Faraj, A.2, Sommadossi, J.-P.2, Pai, S.B.3, Yao, G.-Q.3, Cheng, Y.-C.3 1Dept. of Medicinal Chemistry and Pharmaceutics, Coll. of Pharmacy, The Univ. of Georgia, Athens, GA 30602, 2Dept. of Clinical Pharmacology, Sch. of Medicine, Univ. of Alabama, Birmingham, AL 35294 and 3Dept. of Pharmacology, Sch. of Medicine, Yale Univ., New Haven, CT 06510

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 60 KB

english, 1995

120

2′-deoxy-4′-thio purine nucleosides as potent inhibitors of HBV and HCMV: G. W. Koszalka, G. A. Freeman, S. A. Short, R. Harvey, R. Jansen, G. Szczech, and N. A. Van Draanen, Burroughs Wellcome Co., 3030 Cornwallis Road, Research Triangle Park NC 27709

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

121

Colorimetric assay system for screening antiviral compounds against hepatitis B virus

Kenji Sudo, Kenji Konno, Hiroko Sato, Tomoyuki Yokota, Shiro Shigeta

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 57 KB

english, 1995

122

Novel assay system for hepatitis C virus serine protease inhibitors

Hiroshi Inoue, Yuji Hirowatari, Makoto Hijikata, Tomoyuki Yokota, Kunitada Shimotohno

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

123

Long term antiviral combination chemotherapy for duck hepatitis B virus infection using ganciclovir and nalidixic acid in vivo: C Luscombe, Y Wang, J Pedersen, S Locarnini. Victorian Infectious Diseases Reference Laboratory and Macfarlane Burnet Centre for Medical Research, Fairfield Hospital, Victoria 3078 and Melbourne Pathology, Collingwood, Victoria 3066, Australia

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 55 KB

english, 1995

124

Efficacy of treatment with small dosage Interferon for hepatitis C virus

Wu Zhangqi, Shengqing Lin, Luokeng Peng

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

125

Differential effects on the binding of the transcription factor, AP-1, to its gognate DNA sequence containing the nucleoside analog FIAU

K.A. Staschke, A.J. Baxter, J.C. Scheuring, T.E. Mabry, J.M. Colacino

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

126

Chain terminated hepadnavirus genomes are released as complete extracellular virions: Are serum virion DNA levels a true measure of drug efficacy?: B.E. Korba and J.L. Gerin. Division of Molecular Virology & Immunology, Georgetown University Medical Center, Rockville, MD USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

127

Effect of nucleosides on mitochondrial functions in HepG2 cells: L. Cui,1 R.F. Schinazi,2 G. Gosselin,3 J.-L. Imbach,3 C.K. Chu, 4 R.F. Rando, 5 and J.-P. Sommadossi. 1University of Alabama, Birmingham, AL 35294, USA;1 VA Medical Center/Emory University, Decatur, GA 30033, USA;2 University of Montpellier II, 34095 Montpellier, France;3 University of Georgia, Athens, GA 30602;4 Triplex Pharmaceutical Corporation, The Woodlands, TX 77380, USA.5

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 47 KB

english, 1995

128

Frequency of UL97 mutations related to ganciclovir resistance in clinical CMV isolates: W.L. Drew, S. Guentzel, K.R. Michels, R.C. Miner, S. Chou, VA Medical Center/Oregon Health Sci Univ., Portland and Mt. Zion Med Center of Univ. of California, San Francisco

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

129

Phosphonoacid prodrugs with greatly increased antiviral activity in HCMV-infected cells, in vitro: K.Y. Hostetler, K.A. Aldern, G.D. Kini, C.J. Wheeler and C.N. Sridhar, University of California, San Diego, La Jolla, CA 92093-0676; Veterans Affairs Medical Center, San Diego, CA. 92161; and Vical Inc., San Diego, CA., 92121

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

130

Synthesis and antiviral activity of novel phosphonomethyl ether nucleosides

N. Bischofberger, E.R. Kern, M.S. Chen, D.B. Barkhimer, J.M. Cherrington, J.P. Dougherty, C.U. Kim, W. Lew, D.B. Mendel, K. Moon, A.S. Mulato, M.A. Williams, W. Yang

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

131

Potent anti-viral activity of an antisense oligonucleotide complementary to the intron-exon boundary of human cytomegalovirus genes UL36/37

G.S. Pari, A.K. Field, J.A. Smith

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

132

Inhibition of HCMV DNA processing by a new class of anti-HCMV compounds (benzimidazole ribosides) is mediated through the UL89 gene product

M.R. Underwood, S.C. Stanat, L.B. Townsend, J.C. Drach, K.K. Biron

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

133

Sequential ascending multiple-dose safety and pharmacokinetic study of oral lobucavir (BMS-180194) in asymptomatic volunteers seropositive for HIV and CMV: BG Petty, M Wachsman, MC Jordan, H Burgee, D DeHertogh, D Collins, RS Summerill, DA Jabs, JP Dunn, N Hellmann, B Kringstad, C Fletcher, L Smaldone, PS Lietman, MB Stewart. Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD; University of Minnesota, Minneapolis, MN; and Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ and Wallingford, CT, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

134

Inhibitors of varicella zoster virus thymidine kinase: George E. Wright,1 Federico Focher,2 Hongyan Xu,1 Annalisa Verri,2 Thida Sou1 and Silvio Spadari,2 1 Department of Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655, and 2 Istituto di Genetica Biochimica ed Evoluzionistica, Consiglio Nazionale Delle Ricerche, Pavia 27100, Italy

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

135

A randomized, controlled trial of zovirax* (acyclovlr, ACV) versus netivudine for the treatment of herpes zoster: AP Fiddian* and The International Zoster Study Group, *Wellcome Research Laboratories, Beckenham, Kent, UK

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

136

Anti-influenzavirus-activities of polyoxometalates

S. Shigeta, S. Mori, J. Watanabe, T. Yamase, C.L. Hill, R.F. Schinazi

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

137

Synthetic peptides from conserved regions of RSV, HPIV-3, and MeV fusion proteins are potent antivirals (inhibitors of viral fusion): S.R. Petteway, Jr., S. Barney, A.L. Lambert, K. Guthrie, T. Bucy, J. Erickson, G. Merutka, D.M. Lambert. Trimeris, Inc., Durham, NC

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

138

Prophylactic therapy of respiratory syncytial virus (RSV) infection of rhesus monkeys with monoclonal IgA antibody to RSV

V. Traina-Dorge, K. Soike, J-Y. Zhang, P. Mack, T. Monath, R. Weltzin

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

139

Coxsackievirus B3 mutants resistant to WIN 63843 are attenuated for virulence in mice: Molecular analysis of the drug resistant phenotype: J.M. Groarke, M.A. McKinlay, F.J. Dutko and D.C. Pevear. Sterling Winthrop, Collegeville, PA, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

140

Twice daily intranasal GG167 for experimental influenza A: FG Hayden, JJ Treanor, J Esinhart, CU Eason, and EK Hussey. Univ of Va, Charlottesville, VA, Univ of Rochester, NY, and Glaxo, Inc., Research Triangle Park, NC

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

141

Inhibition of Ebola virus by S-adenosylhomocysteine hydrolase inhibitors

J.W. Huggins, Z.X. Zhang, Kelly Davis, R.A. Coulombe

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

142

Antiviral and immunomodulating activities of the imidazoquinoline S-28463: L. M. Imbertson, J. M. Beaurline, J. F. Gerster, S. J. Gibson, V. L. Horton, R. L. Miller, P. E. Myhre, M. J. Reiter, C. B. Tamulinas, M. A. Tomai. 3M Pharmaceuticals, 3M Center, St. Paul, Minnesota 55144, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

143

Safety of didanosine plus stavudine combination therapy in HIV-infected subjects in a pilot randomized double-blinded trial: R Pollard, D Hardy, D Peterson, J Pottage, N Hellmann, J Skovronski, L Reynolds, V Rutkiewicz, S Ogorzalek, C McLaren, L Dunkle. University of Texas Medical Branch, Galveston, TX; University of California, Los Angeles Medical Center, Los Angeles, CA; University of Texas, Southwestern Medical Center, Dallas, TX; Rush Medical College, Chicago, IL; Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, CT

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 77 KB

english, 1995

144

Oral brivudin versus intravenous acyclovir in the treatment of herpes zoster in immunocompromised patients: a randomized double-blind trial

P. Wutzler, E. De Clercq, K. Wutke, I. Färber

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

145

The efficacy of steroids and acyclovir therapy of herpes zoster in the elderly: RJ Whitley, H Weiss, J Gnann, S Tyring, J Wolf, R Pollard, G Mertz, P Pappas, C Laughlin, L Sherrill, C Schlupner, SJ Soong and the NIAID Collaborative Antiviral Study Group (CASG); The University of Alabama at Birmingham, Birmingham, Alabama USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 41 KB

english, 1995

146

Stereoselective synthesis of (S)- and (R)-penciclovir triphosphate and their activity against viral enzymes: Z. J. Lesnikowski, A. S. Juodawlkis, R. M. Lloyd, Jr., and R. F. Schinazi.* Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and VA Medical Center, Decatur, GA 30033, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 43 KB

english, 1995

147

Synthesis of acyclic nucleotide analogues derived from 2-(aminomethyl)purine bases

A. Holý, M. Hocek, J. Balzarini, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 56 KB

english, 1995

148

Synthesis and biological evaluation of new carbocyclic 2′,3′-didehydro-2′,3′-dideoxy and 3′-deoxy-2′-fluoropyrimidine and purinenucleosides

R. Guedj, E.E.E. Suhas, P.R.T. Frogier, R. Condom, S.R. Challand, A. Kirn, A.M. Aubertin

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

149

Potent topical anti-herpes activity of a lipophilic phosphorus prodrug for the antiviral agent PMEA

A. Glazier, M. Yanachkova, I. Yanachkov, G.E. Wright

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

150

Sulfated xylogalactans from marine algae useful as anti HSV-1 agents: E.B. Damonte, M.C. Matulewicz, A.S. Cerezo, C.E. Coto. *Laboratorio de Virología and **Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

151

Herpes thymidine kinase inhibitors: Resolution and enantioselective synthesis of L-653,180 and water-soluble prodrugs

D.J. Von Langen, J.D. Karkas, R. Bostedor, R. Liou, R.L. Tolman

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

152

HSV-thymidine kinase: a molecular target for transfection imaging in gene therapy of cancer: L.I. Wiebe, E.E. Knaus and K.W. Morin. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2N8

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 73 KB

english, 1995

153

Herpesvirus sensitivity to zovirax* (acyclovir, ACV) and other nucleoside analogues: P Collins, G Darby, Wellcome Research Laboratories, Beckenham, Kent, UK

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

154

In vitro activity of bile acids on herpes simplex virus type-2 (HSV-2) infection: SF Reising, KW Quinn, and LR Stanberry. Children's Hospital Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

155

The development of an in vitro antiviral susceptibility assay using alamar blue: T.H. Belhorn, M.D., Ph.D., and S. Azar. Univ. of Texas Health Sciences Center, Houston, Texas, U.S.A.

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 68 KB

english, 1995

156

Development of anti-HSV screening system using suspension cell line and screening several nucleoside analogues in this method: T. Kira1, A. Kakefuda2, H. Awano2, S. Shuto2, A. Matsuda2, M. Baba3, M. Saneyoshi4, S. Shigeta1 1Department of Microbiology, Fukushima Medical College, Fukushima 960-12, Fukushima 2 Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060, Hokkaido 3 Division of Human Retroviruses, Center for Chronic Viral Diseases, Faculty of Medicine, Kagoshima University, Kagoshima 890, Kagoshima 4 Department of Biological Sciences, The Nishi-Tokyo University, Uenohara 409-01, Yamanashi, Japan

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

157

The in vitro activity of cidofovir against acyclovir-resistant and foscarnet-resistant herpes simplex virus (HSV) isolates: S. Safrin, E. Abarbarchuk, E. Palacios. The Herpes Virus Research Laboratory, San Francisco General Hospital, San Francisco CA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

158

Comparative evaluation of the plaque reduction assay and a microplate ELISA test for antiviral susceptibility testing of herpes simplex virus (HSV) isolates: S. Safrin, E. Palacios, B. Leahy. San Francisco General Hospital, University of California, San Francisco CA and Royal Perth Hospital, Western Australia

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

159

Interactions of reproductive ability of herpes simplex virus (HSV) type I and its variants, resistant to acyclovir (ACV) and phosphonoacetic acid (PAA) with proliferative activity of VERO cells: Nikolaeva S.N., Boreko E.I., Erokhina I.R., Votyakov V.I. Dyelorussian Research Institute for Epidemiology and Microbiology, Minsk, Republic of Belarus

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

160

Antiviral activity of nucleoside derivatives against acyclovir-resistant mutants of herpes simplex virus type 1

Chong-Kyo Lee, Jee Hyun Kim, Hae Soo Kim

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

161

Antiviral drug susceptibility of herpes simplex type 1 (HSV-1) strains emerging under the selective pressure of (S)-1-(3-Hydroxy-2-Phosphonylmethoxypropyl)cytosine (HPMPC) in vitro

G. Andrei, R. Snoeck, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 77 KB

english, 1995

162

Isolation and initial characterization of a herpes simplex virus type 2 (HSV-2) strain with decreased sensitivity to Cidofovir: D.B. Mendel1, D.B. Barkhimer1, E.R. Kern2, and M.S. Chen1. 1Gilead Sciences, Inc., Foster City, CA 94404 and 2Dept. of Pediatrics, Div. of Clinical Virology, Univ. of Alabama, Birmingham, AL 35294

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

163

Acyclovir, as a tool to differentiate between mutants of herpes simplex virus, in mixed infections: Ehud Katz and Kazem Keywan. Department of Virology, Hebrew University-Hadassah Medical School, Jerusalem, Israel

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 81 KB

english, 1995

164

Intracellular metabolism of the novel anti-herpesvirus agent 2-amino-7-[1,3-dihydroxy-2-propoxy)methyl]purine compound S2242 in non-infected and herpesvirus-infected cells

J. Neyts, J. Balzarini, G. Andrei, D. Reymen, R. Snoeck, G. Jähne, I. Winkler, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

165

Purification and photoaffinity labeling of herpes simplex virus type-1 thymidine kinase: T. M. Rechtin#, M. E. Black^, F. Mao#, and R.R. Drake#. Department of Biochemistry and Molecular Biology#, University of Arkansas for Medical Sciences, Little Rock, AR 72205 and Darwin Molecular Corporation^, Bothell, WA 98021

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

166

Improved purification of the HSV protease catalytic domain using immunoaffinity: G. McKercher, D. Thibeault, P.R. Bonneau, R.L. Krogsrud, C. Lawetz, L. Lagacé, M.-J. Massariol, M.G. Cordingley. Bio-Méga/Boehringer Ingelheim Recherche Inc., 2100 me Cunard, Laval, Québec, Canada H7S 2G5

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

167

Peptide disruption of protein-protein complexes: a novel strategy for antiviral therapy

G. Palú, A. Marcello, A. Loregian, M. Pizzato

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 78 KB

english, 1995

168

Activity of hydroxyurea (HU) in combination with several antiviral nucleosides against in vitro replication of herpes simplex type 1 (HSV-1) and type 2 (HSV-2) and varicella-zoster virus (VZV)

R. Snoeck, G. Andrei, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

169

Effect of recombinant human and mouse interferons on herpes simplex virus type 1 replication in vitro and in vivo: U. Wintergerst,1 J.D. Gangemi2, R.J. Whitley3, E.R. Kern3 and S. Chatterjee3. 1University Children's Hospital, Munich, Germany; 2Clemson University Biomedical Alliance, Clemson, SC, USA; and 3University of Alabama School of Medicine, Birmingham, AL, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

170

Antiviral properties of sterically hindered phenol derivatives

O.T. Andreeva, V.I. Votyakov, V.E. Zhelobkovich, D.K. Petrikevich, E.C. Kunevich, V.A. Timoshchuck, O.I. Shadyro

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

171

Influence of the size of the virus inoculum on the efficacy of acyclovir (ACV) and implications for the treatment of herpes simplex labialis: M.B. McKeough and S.L. Spruance, University of Utah, Salt Lake City, Utah, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

172

Antiviral activity of phosphinic cyclocreatine (2-iminoimidazolidine-1-methyl phosphinic acid) against HCMV and HSV-1

B.G. Mulamba, L.J. Hansen, R. Kaddurah-DaouK

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

173

Rapid assay for determining the mode of action of compounds effective against human cytomegalovirus (HCMV): J. McSharry and C. Chutkowski Albany Medical College, Albany, NY 12208

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

174

Rapid determination of antiviral sensitivity of human cytomegalovirus

E Ljungdahl Ståhle, V Sundqvist, A Linde, B Wahren

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

175

Sensitivities of human cytomegalovirus (HCMV) clinical isolates to cidofovir: J.M. Cherrington1, S.J.W. Allen1, A.S. Mulato1, R. Miner2, W.L. Drew2, and M.S. Chen1. 1Gilead Sciences, Inc., Foster City, CA. 94404; 2 Mt. Zion Medical Center, UCSF, San Francisco, CA. 94115

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

176

Selection and characterization of HCMV resistant to the benzimidazole ribonucleoside TCRB: P.M. Bush, S.R. Turk, R.G. Ptak, F.P. Albayya, A.C. Westerman, L. B. Townsend and J. C. Drach, University of Michigan, Ann Arbor, MI 48109; M.R. Underwood and K. K. Biron, Burroughs Wellcome Co., Research Triangle Park, NC 27709 USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

177

Human cytomegalovirus (HCMV) strains selected under selective pressure of phosphonoformate (PFA) are resistant for both PFA and phosphonylmethoxyethyl (PME) derivatives in vitro

R. Snoeck, G. Andrei, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

178

Effects of desferrioxamine on human cytomegalovirus replication and expression of HLA antigens and adhesion molecules in human vascular endothelial cells

J. Cinatl, M Scholz, J.-U. Vogel, H Gümbel, B. Weber, J. Cinatl sen., H. Rabenau, A. Encke, H.-W. Doerr

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

179

The consequence of incorporation of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine by human cytomegalovirus DNA polymerase on DNA elongation: X. F. Xiong, J. L. Smith, and M. S. Chen. Gilead Sciences, Foster City, CA 94404

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

180

Specific anti-cytomegaloviral activity of methotrexate associated with preferential accumulation of drug by infected cells: M. Wachsman, F.M. Hamzeh, H. Saito, and P. S. Lietman. 1 Division of Clinical Pharmacology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

181

Direct quantitation of CMV DNA in leukocytes by bDNA signal amplification assay: J.A. Kolberg, B. Hoo, R. Miner, R. Kelso, J. Wiegand, D. Chernoff, D. Jekic-McMullen, W.L. Drew. Chiron Corporation, Emeryville, CA and UCSF/Mt. Zion Medical Center, San Francisco, CA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

182

Characterization of the guinea pig cytomegalovirus UL97 gene homologue

D.S. Fox, M.R. Schleiss

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

183

Selective elimination of cytomegalovirus infected cells by immunotoxins targeted with various antibodies linked to ricin A chain or gelonin: BB Barnett, DF Smee and RW Sidwell. Institute for Antiviral Research, Utah State University, Logan, UT 84322-5500, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

184

Activities of anti-murine cytomegalovirus (MCMV) immunotoxins used alone or in combination with antiviral agents against MCMV infections: D.F. Smee, K.M. Okleberry, B.B. Barnett, and R.W. Sidwell. Institute for Antiviral Research, Utah State University, Logan, Utah USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

185

Combination of azidothymidine (AZT) with (E)-5-(2-bromovinyl)-2′-deoxyuridine (BVDU) leads to inhibition of the in vitro replication of herpes simplex virus type 1 (HSV-1), type 2 (HSV-2) and varicella-zoster virus (VZV) strains that are deficient in thymidine kinase (TK) activity

G. Andrei, R. Snoeck, J. Balzarini, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

186

Analysis of mutations in the thymidine kinase gene of varicella-zoster virus associated with resistance to 5-iodo-2′-deoxyuridine (IDU) and 5-bromo-2′-deoxyuridine (BrDU)

E. Kodama, S. Mori, S. Shigeta

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

187

QC-PCR accurate determination of rabbit genomic DNA: Evaluation of VZV load in the rabbit ocular infection model: Q Zhu1, M Piatak2, J Guo1, S Yamamoto,1 D Pavan-Langston,1 and EC Dunkel1. 1Schepens Eye Research Institute; Department of Ophthalmology, Harvard Medical School, Boston, MA and 2Gene Labs, Inc. Redwood City, CA, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

188

Some nucleoside analogs with anti-human immunodeficiency virus activity inhibit Replication of Epstein-Barr virus

E.-C. Mar, C.K. Chu, J.-C. Lin

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

189

Antiviral activity of selected nucleoside analogues against human herpes virus type 6

D. Reymen, L. Naesens, J. Balzarini, A. Holy, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

190

Antiviral activity of compounds against human herpesvirus 6

K. Takahashi, S. Shigeta

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

191

Evaluation of antiviral agents against HHV-6 and HHV-7 in human cord blood cells: P. M. Feorino1, J. Black2, K. Kite-Powell2, D. Burns2, R. F. Schinazi1*. Laboratory of Biochemical Pharmacology, Dept. of Pediatrics, Emory University/Veterans Affairs Medical Center, Decatur, GA;1 and Herpesvirus Section, Centers for Disease Control and Prevention, Atlanta, GA,2 USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

192

Spontaneous reactivation of acyclovir resistant (ACVr) thymidine kinase deficient (T K−) herpes simplex virus type 2 (HSV 2) is still dependent upon viral TK expression

J.J. Sasadeusz, S. Safrin, S.L. Sacks

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

193

Comparative effects of famciclovir and valaciclovir on cutaneous and neurological HSV-1 infection in normal and immunocompromised mice: A.M. Thackray and H.J. Field, University of Cambridge, Madingley Road, Cambridge, CB3 OES, UK

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

194

Comparison of the antiviral efficacy of acyclovir and penciclovir in topically treated HSV-infected HRS/J mice: D.W. Selleseth. Wellcome Research Laboratories, Research Triangle Park, North Carolina, U.S.A.

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

195

Comparison of efficacy and toxicity of HPMPC and cyclic HPMPC in animal models for severe herpesvirus infections: E.R. Kern, J. Palmer, C. Hartline, and P.E. Vogt. University of Alabama School of Medicine, Birmingham, AL, U.S.A.

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

196

Hydrocephalus induction in mice infected with herpes simplex virus type 2 after antiviral treatment: X. Yao, and R. F. Schinazi.* Veterans Affairs Medical Center and Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Decatur, Georgia 30033, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

197

Effect of HBPG on the clinical recurrences of ocular herpetic keratitis in squirrel monkeys: HE Kaufman, ED Varnell, GE Wright, and H Xu, LSU Eye Center, New Orleans, LA and *University of Massachusetts Medical School, Worcester, MA USA

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

198

Efficacy of peptide T in the rabbit model of HSV-1-induced keratitis: EC Dunkel1, J Michaelis2, M Sleigh2, J Guo1, P Geary 1, and Q Zhu1. 1 Schepens Eye Research Institute; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA and 2 Peptide Technology Limited, Dee Why, N.S.W., Australia

Journal:

Antiviral Research

Year:

1995

Language:

english

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english, 1995

199

Potentiating effect of dextran sulphate on the antiviral activity of acyclovir and BVDU in the treatment of herpetic keratitis in rabbits: S.N. Pancheva. Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 61 KB

english, 1995

200

Peptidomimetic ribonucleotide reductase inhibitors in the treatment of herpes simplex keratitis in mice

M. Garneau, M.-C. Paré, S. Nawoot, J. Jaramillo, R. Déziel

Journal:

Antiviral Research

Year:

1995

Language:

english

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PDF, 61 KB

english, 1995

201

Significance of high skin fluxes produced by acyclovir topical formulations for achieving therapeutic levels of drug at the target site in the treatment of cutaneous HSV-1 infections in hairless mice: A closer look at the C* concept: Phenil J. Patel1, Abdel-Halim Ghanem1, William I. Higuchi1, Jer Hsu1, V. Srinivasan2 and Earl R. Kern3. 1Dept. of Pharmaceutics and Pharmaceutical Chemistry, Univ. of Utah, Salt Lake City, UT 84112; 2TheraTech, Inc., 417 Wakara Way, Salt Lake City, UT 84108; 3Dept. of Pediatrics, Univ. of Alabama at Birmingham, AL 35294

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

202

Lidakol cream vs zovirax ointment for the treatment of experimental dorsal cutaneous herpes simplex virus type 1(HSV-1) infection in the guinea pig: M.B. McKeough and S.L. Spruance, University of Utah, Salt Lake City, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

203

Comparison of n-docosanol cream (LIDAKOL™) with acyclovir ointment (Zovirax™) in the inhibition of cutaneous herpes simplex virus (HSV) infections in two guinea pig model systems: J.F. Marcelletti, R.R. McFadden, M.H. Khalil, L.E. Pope, R.C. Davis, L.R. Katz, and D.H. Katz. LIDAK Pharmaceuticals, 11077 N. Torrey Pines Road, La Jolla, CA 92037

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

204

Effect of polyanionic compounds on intracutaneous and intravaginal herpes virus infection in mice: Impact on the search for vaginal microbicides

J. Neyts, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

205

Prevention and treatment of experimental genital herpes simplex virus type 2 (HSV-2) infections with topical HPMPC: J. Palmer, P.E. Vogt, and E.R. Kern. University of Alabama School of Medicine, Birmingham, AL, U.S.A.

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 74 KB

english, 1995

206

Evaluation of CRT healing components in two different topically treated cold sore animal models

A. Martin, E.R. Kern, J. Sheridan

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 74 KB

english, 1995

207

Pathogenesis of drug resistant clinical HSV-2 isolates in the guinea pig model of genital herpes: N. Bourne, LR Stanberry, J Ireland and DI Bernstein. Childrens Hosp Res Fdn and Gamble Inst Med Res, Cincinnati, OH, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

208

Civamide (CIV) treatment of primary and recurrent experimental genital herpes: N Bourne, DI Bernstein and LR Stanberry, Children's Hospital Research Foundation, University of Cincinnati, Cincinnati, OH, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

209

Effect of S-28463 in reducing recurrent genital HSV-2 in guinea pigs: D.I. Bernstein, R.L. Miller†, E. Tepe, J.C. Mester, C.J. Harrison‡. J.N. Gamble Inst. of Med. Res., Cincinnati, OH, †3M Pharm., 3M Company, St. Paul, MN, ‡Creighton Univ. and Univ. of Nebraska Med. Center, Omaha, NE, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

210

Psychosocial impact of genital herpes in guinea pigs: effect of 0-2B9¼ therapy: D. Bernstein, N. Boune†, S. Rosenthal†, L. Stanberry†. J. N. Gamble Institute of Medical Research, Cincinnati, OH, †Children's Hospital Research Foundation, Cincinnati, OH

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

211

The phosphonate ganciclovir derivative SR 3745A demonstrates severe toxicity in cell culture and in guinea pigs: E. S. Levine, F. J. Bravo†, D. I. Bernstein†, L. R. Stanberry†, and W. Lewis, *Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, and †Children's Hospital Research Foundation, Cincinnati, OH 45267

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 75 KB

english, 1995

212

Human bone marrow toxicity of a non-nucleoside pyrrolo[2,3-d]pyrimidine: M. R. Nassiri, R. S. Taichman, T. E. Renan, S. G. Emerson, L. B. Townsend, and J. C. Drach. University of Michigan, Ann Arbor, Michigan, 48109-1078, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 75 KB

english, 1995

213

Qualitative and quantitative differences between intracellular penciclovir (PCV) triphosphate (PCVTP) and acyclovir (ACV) triphosphate (ACVTP) in a human schwannoma cell line (SW) infected with varicella zoster virus (VZV): G.M. Bebault, R.A. Wall, B.A. Rennie, E.M. Smyrnis, and S.L. Sacks. Viridae Clinical Sciences Inc. and University of BC, Vancouver, Canada

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

214

A pharmacokinetic/pharmacodynamic approach for the comparison of penciclovir and acyclovir: Utilization of an in vitro model which simulates in vivo pharmacokinetics: F. M. Hamzeh*, H. J. Schaad, P. S. Lietman. Division of Clinical Pharmacology, The Johns Hopkins School of Medicine, Baltimore, Maryland USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 84 KB

english, 1995

215

Pharmacokinetics and distribution of penciclovir to the brain and muscle in the rat studied by microdialysis

L Ståhle, N Borg

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 60 KB

english, 1995

216

High bioavailability and rapid distribution of penciclovir following an oral dose of famciclovir

S. Siederer, M.A. Pue, A.J. Fairless, R.S. Hucker, H. Collie, H. Sourgens

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 60 KB

english, 1995

217

Pharmacokinetics of penciclovir following oral famciclovir in subjects with mild renal impairment

S. Scott, S. Siederer

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 53 KB

english, 1995

218

Tissue distribution and bioavailability of cyclic HPMPC, an intracellular prodrug of HPMPC

W.A. Lee, J.-P. Shaw, A. Bidgood, E. Eisenberg, K.C. Cundy

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 53 KB

english, 1995

219

Efficacy and pharmacokinetics of topical HPMPC in a guinea pig model of genital herpes: E.R. Kern1, J. Palmer1, P.E. Vogt1, K. Cundy2, M.J.M. Hitchcock2, and J.-P. Sommadossi1. 1University of Alabama School of Medicine, Birmingham, AL; and 2Gilead Sciences, Inc., Foster City, CA, U.S.A.

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

220

Inhibition of dihydropyrimidine dehydorogenase by 5-(E-2-bromovinyl)uracil (BV-Ura) and recovery of rat liver DPD activity after administration of BV-Ura or sorivudine

H. Machida, K. Endo, Y. Watanabe, N. Ashida, S. Sakata

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

221

Development of HSV-2 type-specific antibodies to glycoprotein B in HSV-2 seronegative individuals following immunization with a recombinant gB2/gD2/adjuvant vaccine: D. Goade, R. Bell, G.J. Mertz, R. Burke, A.G.M. Langenberg, S. Jenison. University of New Mexico, Albuquerque, NM, USA; Chiron Corporation, Emeryville, CA, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 74 KB

english, 1995

222

Preclinical safety assessment of valtrex* (valaciclovir, VACV) the l-valyl ester of acyclovir (ACV): GM Szczech, P de Miranda, Burroughs Wellcome Co., Research Triangle Park, North Carolina, USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 74 KB

english, 1995

223

A randomized, double-blind study of the efficacy and safety of oral ganciclovir for the prevention of cytomegalovirus disease in HIV-infected persons: J. P. Lalezari for the SYNTEX GANCICLOVIR STUDY GROUP, Mount Zion Medical Center, UCSF, S.F., CA and Syntex Research, Palo Alto, CA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 61 KB

english, 1995

224

Sorivudine (BV-ara-U) for the treatment of complicated refractory varicella zoster virus infection in HIV-infected patients: DR Burdge1, R Voigt2, L Gage1, JI Lindley3, S Sacks1. Department of Medicine, University of British Columbia, Vancouver BC Canada1, Department of Ophthalmology, University of British Columbia, Vancouver BC Canada3, St. Paul's Hospital, Vancouver BC Canada2

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 61 KB

english, 1995

225

Famciclovir: Effect on pain in herpes zoster

R.H. Dworkin, R.J. Boon, D.R.J. Grfffin

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

226

Covariates in herpes zoster and interpretation of clinical trial data

R.H. Dworkin, R.J. Boon, D.R.J. Griffin

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

227

WIN 63843, a metabolically stable broad spectrum antipicornaviral compound: G.D. Diana, P. Rudewicz, D.C. Pevear, T.J. Nitz, D.J. Aldous, D.T. Robinson, F.J. Dutko, C. Aldi, M. Reuman, T.R. Bailey, R. Czerniak, T. Block and R. Roland. Sterling Winthrop Pharmaceuticals Research Division, Collegeville, Pennsylvania USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 53 KB

english, 1995

228

Antipicornavirus activity of SCH 47802: In vitro and in vivo studies: S. Cox, P. Buontempo, J. Wright-Minogue, A. Skelton, J. DeMartino, E. Rozhon, C. Linn, V. Girijavallablan, J. Schwartz, and J. O'Connell. Schering-Plough Research Institute, Kenilworth, NJ

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 53 KB

english, 1995

229

Mechanism of action of SCH 47802, an antipicornavirus molecule

P. Buontempo, J. Wright-Minogue, S. Cox, J. DeMartino, V. Girijavallablan, E. Rozhon, J. Schwartz, J. O'Connell

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 56 KB

english, 1995

230

Anti-picornavirus activity of new substituted flavons and flavanones

P Tomao, C. Conti, N. Orsi, N. Desideri, I. Sestili, M.L. Stein

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 56 KB

english, 1995

231

Effects of the nucleoside-analogue antiviral agent ribavirin in persistently coxsackie-virus B3 infected human myocardial fibroblasts

A. Helm, M. Stille-Siegener, C. Brehm, I. Grumbach, H.R. Figulla, J. Drescher

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

232

Aporphinoid alkaloid glaucinone: A selective inhibitor of poliovirus replication

A.S. Galabov, L. Nikolaeva, S. Philipov

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

233

Rapid in vivo development of influenza a (H3N2) virus resistance to amantadine and rimantadine: R.W. Sidwell, K.W. Bailey, M.H. Wong, A.G. Morrison, and J.H. Huffman. Inst. for Antiviral Research, Utah State University, Logan, UT 84322-5600 USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 76 KB

english, 1995

234

Inhibitory effect of a series of protease inhibitors on influenza virus replication in vitro

M. Hosoya, H. Kawamural, T. Ishii, H. Suzuki, J. Watanabe, S. Shigeta

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 76 KB

english, 1995

235

Evaluation of aerosolized aprotinin therapy for influenza And parainfluenza infections in humans

A.V. Ovcharenko, L.S. Kirzhner, N.A. Malyshev, O.P. Zhirnov

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

236

Anti-respiratory syncytial virus activity of selected polyoxometalates

D.L. Barnard, C.L. Hill, T.L. Gage, R.W. Sidwell, R.F. Schinazi

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

237

Antiviral effect of coumarin analogue against respiratory syncytical virus infection in vitro and in vivo

ZQ. Yang, H. Xiao, YW. Liu, JJ. Liu, L. Wen

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 72 KB

english, 1995

238

Synthetic peptides from conserved regions of respiratory syncytial virus fusion (F) protein are potent inhibitors of viral fusion: A.L. Lambert, S. Barney, K. Guthrie, R. Medinas, D.E. Davis-Rhodes, T. Bucy, J. Erickson, G. Merutka, S.R. Petteway, Jr., D.M. Lambert. Trimeris, Inc., Durham, NC

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 72 KB

english, 1995

239

Comparative inhibitory effects of ribavirin, pyrazofurin, and EICAR on measles (SSPE) virus replication in vitro and in vivo

M. Hosoya, Y. Honda, T. Ishii, H. Suzuki, S. Mori, S. Shigeta

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 57 KB

english, 1995

240

An antiviral synthetic coiled-coil peptide displays sustained blood levels in rats: D.M. Lambert, T. Venetta, E.I. DiMassimo, J. Matthews, S.R. Petteway, Jr. Trimeris, Inc., Durham, NC, and Research Triangle Institute, RTP, NC

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

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english, 1995

241

Synthetic peptides from conserved regions of measles virus fusion proteins are potent inhibitors of viral fusion: K. Guthrie, S. Barney, D.E. Davis-Rhodes, A.L. Lambert, R. Medinas, T. Bucy, J. Erickson, G. Merutka, S.R. Petteway, Jr., D.M. Lambert. Trimeris, Inc., Durham, NC

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

242

Synthetic peptides from conserved regions of human parainfluenza type 3 virus fusion protein are potent inhibitors of viral fusion: S. Barney, A.L. Lambert, K. Guthrie, R. Medinas, D.E. Davis-Rhodes, T. Bucy, J. Erickson, G. Merutka, S.R. Petteway, Jr., D.M. Lambert. Trimeris, Inc., Durham, NC

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

243

Plant polysaccharide antiviral agents from Astragalus and Sterculia species: D.F. Smee1 and A.J. Verbiscar.2 1Institute for Antiviral Research, Utah State University, Logan, Utah and 2Anver Bioscience Design, Inc., Sierra Madre California USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 62 KB

english, 1995

244

Drug interactions with mopyridone

L. Tantcheva, D. Rangelova

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 62 KB

english, 1995

245

Effect of topical corticosteroids on the antiviral inhibitory activity of topical (S)-HPMPC in the AD5/NZ rabbit ocular model: YJ Gordon, EG Romanowski, & T Araullo-Cruz, University of Pittsburgh, Pittsburgh PA., USA

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

246

Inducibility of squamous differentiation by interferons determines antigen presentation in HPV negative and positive keratinocytes in vivo and in vitro

Stephen K. Tyring, Istvan Arany, Miriam M. Brysk

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 71 KB

english, 1995

247

Squamous differentiation in HPV negative and positive keratinocytes determines the extent of interferon-induced growth arrest: Istvan Arany1, Miriam M. Brysk1,2, Henry Brysk2 and Stephen K. Tyring1,2, 1 Department of Microbiology and Immunology and 2Department of Dermatology, The University of Texas Medical Branch, Galveston, Texas

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

248

Antiviral effect on infectious pancreatic necrosis virus replication

M. Jashés, A.M. Sandino, E. De Clercq

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 69 KB

english, 1995

249

Highly selective inhibitors of terminal deoxynucleotidyl transferase in cell free systems

A.A. Krayevsky, N.B. Dyatkina, D.G. Semizarov, M. von Janta-Lipinski

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

250

Effects of inhibitors of intracellular transport on the replication of Junin virus: E.B. Damonte, N.A. Candurra. Laboratorio de Virología, Facultad de Ciencías Exactas y Naturales, Universidad de Buenos Aíres, 1428 Buenos Aires Argentina

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 65 KB

english, 1995

251

Haemorrhagic fever with renal syndrome (KOrean haemorrhagic fever in Korea) a challenge in diagnosis & treatment: Report of 10 cases with atypical presentation: Smith JI*, Huggins JW, Lofts RS, Roasi C**, Korch GW*, Arthur JD**, Choi BJ, Yi SH and Petzold RS* From the Departments of Pathology & Area Laboratory Services, Medicine and Preventive Medicine, 121 General Hospital, Yongsan, Seoul Korea, APO, AP 96205 * and US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD **

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 75 KB

english, 1995

252

Modulation of antiviral immune responses by exogenous cytokines effects of TNF-α, β, interleukin-1, interleukin-2 on the immunogenicity of an inactivated tick-born encephalitis vaccine

E.A. Kashentseva, G.M. Ignatyev, V.P. Leskov, A.G. Kusliy

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 75 KB

english, 1995

253

Inhibition of HIV-1 infection of macrophages and H9 cells by free or liposome-encapsulated L-689,502, an inhibitor of the viral protease

E. Pretzer, D. Flasher, N. Düzgünes

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 82 KB

english, 1995

254

The cyclic congener of cidofovir has reduced nephrotoxicity in three species

M.J.M. Hitchock, S.A. Lacy, J.R. Lindsey, E.R. Kern

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 82 KB

english, 1995

255

Therapeutic effect of L-HSA-AraAMP on serum DHBV-DNA in DHBV infected duckling

Hui-wu Yang, Ling-xia Zhang, Dong-ping Liu, Hui-fei Wang, Sen Shao

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 47 KB

english, 1995

256

Antiviral activity of CH31 against HHV-6 in vitro

Hui-wu Yang, Xin-quan Zhang, Dong-ping Liu, Sen shao

Journal:

Antiviral Research

Year:

1995

Language:

english

File:

PDF, 47 KB

english, 1995

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