Jeffrey J. Hale: search on Z-Library

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51

ChemInform Abstract: 1,3,4-Trisubstituted Pyrrolidine CCR5 Receptor Antagonists. Part 2. Lead Optimization Affording Selective, Orally Bioavailable Compounds with Potent anti-HIV Activity.

Jeffrey J. Hale, et al. et al.

Journal:

Year:

2002

File:

PDF, 28 KB

2002

52

1,3,4-Trisubstituted Pyrrolidine CCR5 Receptor Antagonists. Part 3. Polar Functionality and Its Effect on anti-HIV-1 Activity.

Jeffrey J. Hale, et al. et al.

Journal:

Year:

2003

File:

PDF, 137 KB

2003

53

Potent S1P Receptor Agonists Replicate the Pharmacologic Actions of the Novel Immune Modulator FTY720.

Jeffrey J. Hale, et al. et al.

Journal:

Year:

2004

File:

PDF, 13 KB

2004

54

Selecting Against S1P3 Enhances the Acute Cardiovascular Tolerability of 3-(N-Benzyl)aminopropylphosphonic Acid S1P Receptor Agonists.

Jeffrey J. Hale, et al. et al.

Journal:

Year:

2004

File:

PDF, 18 KB

2004

55

Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl–coenzyme A dehydrogenase deficiency

William R. Treem, Piero Rinaldo, Daniel E. Hale, Charles A. Stanley, David S. Millington, Jeffrey S. Hyams, Sandra Jackson, Douglass M. Turnbull

Journal:

Year:

1994

Language:

english

File:

PDF, 762 KB

english, 1994

56

Color and Morphology of Lava Flows on Io

Jennifer L. Piatek, Sarah B.Z. McElfresh, Jeffrey M. Byrnes, Amy Snyder Hale, David A. Crown

Journal:

Year:

2000

Language:

english

File:

PDF, 401 KB

english, 2000

57

Carbon overcoats with controlled properties: non-destructive ellipsometry evaluation

William A. McGahan, Tim Makovicka, Jeffrey Hale, John A. Woolam

Journal:

Surface and Coatings Technology

Year:

1993

Language:

english

File:

PDF, 300 KB

english, 1993

58

Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720

Jeffrey J. Hale, Lin Yan, William E. Neway, Richard Hajdu, James D. Bergstrom, James A. Milligan, Gan-Ju Shei, Gary L. Chrebet, Rosemary A. Thornton, Deborah Card, Mark Rosenbach, HughRosen, Suzanne M

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 290 KB

english, 2004

59

Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists

Jeffrey J. Hale, George Doherty, Leslie Toth, Sander G. Mills, Richard Hajdu, Carol Ann Keohane, Mark Rosenbach, James Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstrom, Deborah Card, Michael Forre

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 269 KB

english, 2004

60

The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists

Jeffrey J. Hale, George Doherty, Leslie Toth, Zhen Li, Sander G. Mills, Richard Hajdu, Carol Ann Keohane, Mark Rosenbach, James Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstrom, Deborah Card, Hugh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 262 KB

english, 2004

61

Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors

Lin Yan, Jeffrey J. Hale, Christopher L. Lynch, Richard Budhu, Amy Gentry, Sander G. Mills, Richard Hajdu, Carol Ann Keohane, Mark J. Rosenbach, James A. Milligan, Gan-Ju Shei, Gary Chrebet, James Ber

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 306 KB

english, 2004

62

2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors

Lin Yan, Richard Budhu, Pei Huo, Christopher L. Lynch, Jeffrey J. Hale, Sander G. Mills, Richard Hajdu, Carol A. Keohane, Mark J. Rosenbach, James A. Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 136 KB

english, 2006

63

Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes

Lin Yan, Pei Huo, George Doherty, Lesile Toth, Jeffrey J. Hale, Sander G. Mills, Richard Hajdu, Carol A. Keohane, Mark J. Rosenbach, James A. Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstrom, Debo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 132 KB

english, 2006

64

Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

Songnian Lin, Matthew Lombardo, Sunita Malkani, Jeffrey J. Hale, Sander G. Mills, Kevin Chapman, James E. Thompson, Wen Xiao Zhang, Ruixiu Wang, Rose M. Cubbon, Edward A. O’Neill, Silvi Luell, Ester C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 660 KB

english, 2009

65

Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists

Wu Du, James P. Jewell, Linus S. Lin, Vincent J. Colandrea, Jing C. Xiao, Julie Lao, Chun-Pyn Shen, Thomas J. Bateman, Vijay B.G. Reddy, Sookhee N. Ha, Shrenik K. Shah, Tung M. Fong, Jeffrey J. Hale,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 963 KB

english, 2009

66

A ‘one-pot’ synthesis of α-1,2,4-oxadiazolo esters from malonic diesters and amidoximes under solvent-free conditions

Wu Du, William K. Hagmann, Jeffrey J. Hale

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 107 KB

english, 2006

67

A one-pot synthesis of 3-substituted-5-carbonylmethyl-1,2,4-oxadiazoles from β-keto esters and amidoximes under solvent-free conditions

Wu Du, Quang Truong, Hongbo Qi, Yan Guo, Harry R. Chobanian, William K. Hagmann, Jeffrey J. Hale

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 143 KB

english, 2007

68

Prospects for IR emissivity control using electrochromic structures

Jeffrey S. Hale, John A. Woollam

Journal:

Thin Solid Films

Year:

1999

Language:

english

File:

PDF, 401 KB

english, 1999

69

Microstructural characterization of SiOx surface contaminants on ashed aluminum thin films

R.A. Synowicki, Jeffrey S. Hale, R.D. Kubik, S. Nafis, John A. Woollam

Journal:

Surface and Coatings Technology

Year:

1997

Language:

english

File:

PDF, 992 KB

english, 1997

70

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 1: discovery of the pyrrolidine scaffold and determination of its stereochemical requirements

Jeffrey J. Hale, Richard J. Budhu, Sander G. Mills, Malcolm MacCoss, Lorraine Malkowitz, Salvatore Siciliano, Sandra L. Gould, Julie A. DeMartino, Martin S. Springer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 158 KB

english, 2001

71

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2: lead optimization affording selective, orally bioavailable compounds with potent Anti-HIV activity

Jeffrey J. Hale, Richard J. Budhu, Edward B. Holson, Paul E. Finke, Bryan Oates, Sander G. Mills, Malcolm MacCoss, Sandra L. Gould, Julie A. DeMartino, Martin S. Springer, Salvatore Siciliano, Lorrain

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

72

CCR5 antagonists: bicyclic isoxazolidines as conformationally constrained N-1-substituted pyrrolidines

Christopher L Lynch, Amy L Gentry, Jeffrey J Hale, Sander G Mills, Malcolm MacCoss, Lorraine Malkowitz, Martin S Springer, Sandra L Gould, Julie A DeMartino, Salvatore J Siciliano, Margaret A Cascieri

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

73

A facile synthesis of the novel Neurokinin A antagonist SR 48968

Jeffrey J. Hale, Paul E. Finke, Malcolm MacCoss

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 261 KB

english, 1993

74

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 3: polar functionality and its effect on anti-HIV-1 activity

Jeffrey J Hale, Richard J Budhu, Sander G Mills, Malcolm MacCoss, Sandra L Gould, Julie A DeMartino, Martin S Springer, Salvatore J Siciliano, Lorraine Malkowitz, William A Schleif, Daria Hazuda, Mich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

75

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists: modifications of the arylpropylpiperidine side chains

Christopher L. Lynch, Christopher A. Willoughby, Jeffrey J. Hale, Edward J. Holson, Richard J. Budhu, Amy L. Gentry, Keith G. Rosauer, Charles G. Caldwell, Ping Chen, Sander G. Mills, Malcolm MacCoss,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 160 KB

english, 2003

76

Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-dPhe-Arg-Trp-Lys]-NH2

Christopher Fotsch, Duncan M Smith, Jeffrey A Adams, Janet Cheetham, Michael Croghan, Elizabeth M Doherty, Clarence Hale, Mark A Jarosinski, Michael G Kelly, Mark H Norman, Nuria A Tamayo, Ning Xi, Ja

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

77

Outcome of hematopoietic stem cell transplantation for pediatric patients with therapy-related acute myeloid leukemia or myelodysplastic syndrome

Paul Woodard, Raymond Barfield, Gregory Hale, Edwin Horwitz, Wing Leung, Raul Ribeiro, Jeffrey Rubnitz, Deo Kumar Srivistava, Xin Tong, Usman Yusuf, Susana Raimondi, Ching-Hon Pui, Rupert Handgretinge

Journal:

Pediatric Blood & Cancer

Year:

2006

Language:

english

File:

PDF, 102 KB

english, 2006

78

Randomized, Double-Blind, Placebo-Controlled, Dose-Escalating Study of Aerosolized Interferon Gamma-1b in Patients With Mild to Moderate Cystic Fibrosis Lung Disease

Richard B. Moss, Nicole Mayer-Hamblett, Jeffrey Wagener, Cori Daines, Kathryn Hale, Richard Ahrens, Ronald L. Gibson, Paula Anderson, George Retsch-Bogart, Samya Z. Nasr, Imre Noth, David Waltz, Pamel

Journal:

Pediatric Pulmonology

Year:

2005

Language:

english

File:

PDF, 129 KB

english, 2005

79

Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths

Jeffrey A. Bell, Keith P. Wilson, Xue-Jun Zhang, Howard R. Faber, Hale Nicholson, Brian W. Matthews

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 1.02 MB

english, 1991

80

Nuclear data for radiotherapy: Presentation of a new ICRU report and IAEA initiatives

Mark B. Chadwick, Dan T. L. Jones, Henry H. Barschall, Randall S. Caswell, Paul M. DeLuca, Jean -Pierre Meulders, André Wambersie, Helmut Schuhmacher, Philllip G. Young, Gerald M. Hale, Jeffrey V. Sie

Journal:

Strahlentherapie und Onkologie

Year:

1999

Language:

english

File:

PDF, 472 KB

english, 1999

81

Beyond data management: how ecoinformatics can benefit environmental monitoring programs

Stephen S. Hale, Jeffrey W. Hollister

Journal:

Environmental Monitoring and Assessment

Year:

2009

Language:

english

File:

PDF, 259 KB

english, 2009

82

Experimental evidence of how prior experience as an auditor influences managers’ strategic reporting decisions

Kendall O. Bowlin, Jeffrey Hales, Steven J. Kachelmeier

Journal:

Review of Accounting Studies

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

83

Low Earth orbit effects on indium tin oxide and polyester and comparison with laboratory simulations

R.A. Synowicki, Jeffrey S. Hale, N.J. Ianno, John A. Woollam, Paul D.Hambourger

Journal:

Surface and Coatings Technology

Year:

1993

Language:

english

File:

PDF, 450 KB

english, 1993

84

Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 2: Discovery of potent, selective, and orally bioavailable compounds

Dong-Ming Shen, Min Shu, Christopher A. Willoughby, Shrenik Shah, Christopher L. Lynch, Jeffrey J. Hale, Sander G. Mills, Kevin T. Chapman, Lorraine Malkowitz, Martin S. Springer, Sandra L. Gould, Jul

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 218 KB

english, 2004

85

Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720

Jeffrey J. Hale, William Neway, Sander G. Mills, Richard Hajdu, Carol Ann Keohane, Mark Rosenbach, James Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstrom, Deborah Card, Gloria C. Koo, Sam L. Kopra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 285 KB

english, 2004

86

Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties

Dooseop Kim, Liping Wang, Jeffrey J. Hale, Christopher L. Lynch, Richard J. Budhu, Malcolm MacCoss, Sander G. Mills, Lorraine Malkowitz, Sandra L. Gould, Julie A. DeMartino, Martin S. Springer, Daria

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 193 KB

english, 2005

87

2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists

Vincent J. Colandrea, Irene E. Legiec, Pei Huo, Lin Yan, Jeffrey J. Hale, Sander G. Mills, James Bergstrom, Deborah Card, Gary Chebret, Richard Hajdu, Carol Ann Keohane, James A. Milligan, Mark J. Ros

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

88

Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor

Petr Vachal, Leslie M. Toth, Jeffrey J. Hale, Lin Yan, Sander G. Mills, Gary L. Chrebet, Carol A. Koehane, Richard Hajdu, James A. Milligan, Mark J. Rosenbach, Suzanne Mandala

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

89

SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties

Lin Yan, Pei Huo, Jeffrey J. Hale, Sander G. Mills, Richard Hajdu, Carol A. Keohane, Mark J. Rosenbach, James A. Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstrom, Deborah Card, Suzanne M. Mandala

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

90

Prevention of human leukocyte elastase-mediated lung damage by 3-alkyl-4-azetidinones

William K. Hagmann, Shrenik K. Shah, Conrad P. Dorn, Laura A. O'Grady, Jeffrey J. Hale, Pau.E. Finke, Kevan R. Thompson, Karen a. Brause, Bonnie M. Ash, Hazel Weston, M.Ellen Dahlgren, Alan L. Maycock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 484 KB

english, 1991

91

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 4: Synthesis of N-1 acidic functionality affording analogues with enhanced antiviral activity against HIV

Christopher L Lynch, Jeffrey J Hale, Richard J Budhu, Amy L Gentry, Sander G Mills, Kevin T Chapman, Malcolm MacCoss, Lorraine Malkowitz, Martin S Springer, Sandra L Gould, Julie A DeMartino, Salvator

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

92

Pleistocene isolation and recent gene flow in Haliotis asinina, an Indo-Pacific vetigastropod with limited dispersal capacity

, BENARDINE JEFFREY, PETER HALE, BERNARD M. DEGNAN, SANDIE M. DEGNAN

Journal:

Molecular Ecology

Year:

2007

Language:

english

File:

PDF, 305 KB

english, 2007

93

The Acceptability Cline in VP Ellipsis

Christina S. Kim, Gregory M. Kobele, Jeffrey T. Runner, John T. Hale

Journal:

Year:

2011

Language:

english

File:

PDF, 894 KB

english, 2011

94

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

Wei, Xiaomu, Walia, Vijay, Lin, Jimmy C, Teer, Jamie K, Prickett, Todd D, Gartner, Jared, Davis, Sean, Stemke-Hale, Katherine, Davies, Michael A, Gershenwald, Jeffrey E

Journal:

Nature Genetics

Year:

2011

Language:

english

File:

PDF, 403 KB

english, 2011

95

Questioning the Delphic Oracle

Hale, John R., Zeilinga De Boer, Jelle, Chanton, Jeffrey P., Spiller, Henry A.

Journal:

Scientific American

Year:

2003

Language:

english

File:

PDF, 658 KB

english, 2003

96

Long-term nutrient and water utilization during micropropagation of Cattleya on a liquid/membrane system

Jeffrey W. Adelberg, Nenita V. Desamero, S. Andrew Hale, Roy E. Young

Journal:

Plant Cell, Tissue and Organ Culture

Year:

1997

Language:

english

File:

PDF, 68 KB

english, 1997

97

Summary of the MAIA Working Conference

M. Patricia Bradley, Barbara S. Brown, Stephen S. Hale, Frederick W. Kutz, Ronald B. Landy, R. Shedlock, R. Mangold, Alvin Morris, Walter Galloway, Jeffrey S. Rosen, R. Pepino, Bruce Wiersma

Journal:

Environmental Monitoring and Assessment

Year:

2000

File:

PDF, 597 KB

2000

98

Directional Preferences, Information Processing, and Investors' Forecasts of Earnings

Journal:

Journal of Accounting Research

Year:

2007

Language:

english

File:

PDF, 571 KB

english, 2007

99

Implicit Employment Contracts: The Limits of Management Reputation for Promoting Firm Productivity

JEFFREY HALES, MICHAEL G. WILLIAMSON

Journal:

Journal of Accounting Research

Year:

2010

Language:

english

File:

PDF, 484 KB

english, 2010

100

A Rational Utilization of High-Throughput Screening Affords Selective, Orally Bioavailable 1-Benzyl-3-carboxyazetidine Sphingosine-1-phosphate-1 Receptor Agonists

Hale, Jeffrey J., Lynch, Christopher L., Neway, William, Mills, Sander G., Hajdu, Richard, Keohane, Carol Ann, Rosenbach, Mark J., Milligan, James A., Shei, Gan-Ju, Parent, Stephen A., Chrebet, Gary,

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004