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1

Fc-Fusion Drugs Have FcγR/C1q Binding and Signaling Properties That May Affect Their Immunogenicity

Lagassé, H. A. Daniel, Hengel, Hartmut, Golding, Basil, Sauna, Zuben E.

Journal:

The AAPS Journal

Year:

2019

Language:

english

File:

PDF, 2.52 MB

english, 2019

2

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

Sauna, Zuben E., Shukla, Suneet, Ambudkar, Suresh V.

Journal:

Molecular BioSystems

Year:

2005

Language:

english

File:

PDF, 469 KB

english, 2005

3

Understanding the contribution of synonymous mutations to human disease

Sauna, Zuben E., Kimchi-Sarfaty, Chava

Journal:

Nature Reviews Genetics

Year:

2011

Language:

english

File:

PDF, 621 KB

english, 2011

4

Exposing synonymous mutations

Hunt, Ryan C., Simhadri, Vijaya L., Iandoli, Matthew, Sauna, Zuben E., Kimchi-Sarfaty, Chava

Journal:

Trends in Genetics

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

5

Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima

Chung-Jung Tsai, Zuben E. Sauna, Chava Kimchi-Sarfaty, Suresh V. Ambudkar, Michael M. Gottesman, Ruth Nussinov

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

6

Analysis of F9 point mutations and their correlation to severity of haemophilia B disease

N. Hamasaki-Katagiri, R. Salari, V. L. Simhadri, S. C. Tseng, E. Needlman, N. C. Edwards, Z. E. Sauna, V. Grigoryan, A. A. Komar, T. M. Przytycka, C. Kimchi-Sarfaty

Journal:

Year:

2012

Language:

english

File:

PDF, 204 KB

english, 2012

7

A Study on Implications of Implementing Green HRM in the Corporate Bodies with Special Reference to Developing Nations

Ramasamy, Adimuthu, Inore, Ishmael, Sauna, Richard

Journal:

International Journal of Business and Management

Year:

2017

Language:

english

File:

PDF, 256 KB

english, 2017

8

Intellectual disability in patients with epilepsy with eyelid myoclonias

Arvio, Maria, Sauna-aho, Oili, Nyrke, Timo, Bjelogrlic-Laakso, Nina

Journal:

SAGE Open Medical Case Reports

Year:

2018

Language:

english

File:

PDF, 103 KB

english, 2018

9

Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans

Suneet Shukla, Zuben E. Sauna, Rajendra Prasad, Suresh V. Ambudkar

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 824 KB

english, 2004

10

Signs indicating dementia in Down, Williams and Fragile X syndromes

Sauna-Aho, Oili, Bjelogrlic-Laakso, Nina, Siren, Auli, Arvio, Maria

Journal:

Molecular Genetics & Genomic Medicine

Year:

2018

Language:

english

File:

PDF, 479 KB

english, 2018

11

Efficient Propagation of Circulating Tumor Cells: A First Step for Probing Tumor Metastasis

Xiao, Jerry, McGill, Joseph R., Stanton, Kelly, Kassner, Joshua D., Choudhury, Sujata, Schlegel, Richard, Sauna, Zuben E., Pohlmann, Paula R., Agarwal, Seema

Journal:

Year:

2020

File:

PDF, 1.75 MB

2020

12

Evaluating and Mitigating the Immunogenicity of Therapeutic Proteins

Sauna, Zuben E., Lagassé, Daniel, Pedras-Vasconcelos, Joao, Golding, Basil, Rosenberg, Amy S.

Journal:

Trends in Biotechnology

Year:

2018

Language:

english

File:

PDF, 2.68 MB

english, 2018

13

Cognition in adults with Williams syndrome—A 20‐year follow‐up study

Sauna‐aho, Oili, Bjelogrlic‐Laakso, Nina, Sirén, Auli, Kangasmäki, Virpi, Arvio, Maria

Journal:

Molecular Genetics & Genomic Medicine

Year:

2019

Language:

english

File:

PDF, 576 KB

english, 2019

14

Comparative Metabolomics in Glycine max and Glycine soja under Salt Stress To Reveal the Phenotypes of Their Offspring

Lu, Yonghai, Lam, Honming, Pi, Erxu, Zhan, Qinglei, Tsai, Sauna, Wang, Chunmei, Kwan, Yiuwa, Ngai, Saiming

Journal:

Journal of Agricultural and Food Chemistry

Year:

2013

Language:

english

File:

PDF, 3.18 MB

english, 2013

15

TCPro: an In Silico Risk Assessment Tool for Biotherapeutic Protein Immunogenicity

Yogurtcu, Osman N., Sauna, Zuben E., McGill, Joseph R., Tegenge, Million A., Yang, Hong

Journal:

The AAPS Journal

Year:

2019

Language:

english

File:

PDF, 3.18 MB

english, 2019

16

[IEE 18th International Conference and Exhibition on Electricity Distribution (CIRED 2005) - Turin, Italy (6-9 June 2005)] 18th International Conference and Exhibition on Electricity Distribution (CIRED 2005) - A new technique for short circuit fault location in distribution networks

Vahamaki, O., Sauna-aho, S., Hanninen, S., Lehtonen, M.

Year:

2005

Language:

english

File:

PDF, 584 KB

english, 2005

17

Synthesis and analysis of polyethylene glycol linked P-glycoprotein-specific homodimers based on (−)-stipiamide

Merritt B Andrus, Timothy M Turner, Emily P Updegraff, Zuben E Sauna, Suresh V Ambudkar

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 77 KB

english, 2001

18

Genomics and the mechanism of P-glycoprotein (ABCB1)

Zuben E. Sauna, In-Wha Kim, Suresh V. Ambudkar

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

19

A VEHICLE MOTION SIMULATOR, VEMOSIM, COMBINED WITH DIGITAL ROAD DATA – A NEW WAY FOR QUANTIFYING IMPACTS OF ITS AND OTHER MEASURES

Sauna-aho, Jussi, Koskinen, Olavi H, Sauna-aho, Pasi

Journal:

Research in Transportation Economics

Year:

2004

Language:

english

File:

PDF, 230 KB

english, 2004

20

Detection of Intracellular Factor VIII Protein in Peripheral Blood Mononuclear Cells by Flow Cytometry

Pandey, Gouri Shankar, Tseng, Sandra C., Howard, Tom E., Sauna, Zuben E.

Journal:

BioMed Research International

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

21

Translational and transcriptional responses in human primary hepatocytes under hypoxia

Hettiarachchi, Gaya K, Katneni, Upendra K, Hunt, Ryan C, Kames, Jacob M, Athey, John C, Bar, Haim, Sauna, Zuben E, McGill, Joseph R, Ibla, Juan C, Kimchi-Sarfaty, Chava

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2019

Language:

english

File:

PDF, 3.36 MB

english, 2019

22

Evidence for the interaction of imatinib at the transport-substrate site(s) of the multidrug-resistance-linked ABC drug transporters ABCB1 (P-glycoprotein) and ABCG2

Shukla, S, Sauna, Z E, Ambudkar, S V

Journal:

Year:

2007

Language:

english

File:

PDF, 107 KB

english, 2007

23

Pharmacogenetics and the immunogenicity of protein therapeutics

Yanover, Chen, Jain, Nisha, Pierce, Glenn, Howard, Tom E, Sauna, Zuben E

Journal:

Nature Biotechnology

Year:

2011

Language:

english

File:

PDF, 545 KB

english, 2011

24

Delayed auditory processing underlying stimulus detection in Down syndrome

Eero Pekkonen, Daria Osipova, Oili Sauna-Aho, Maria Arvio

Journal:

Year:

2007

Language:

english

File:

PDF, 140 KB

english, 2007

25

Importance of the Conserved Walker B Glutamate Residues, 556 and 1201, for the Completion of the Catalytic Cycle of ATP Hydrolysis by Human P-glycoprotein (ABCB1)

Sauna, Zuben E., Müller, Marianna, Peng, Xiang-Hong, Ambudkar, Suresh V.

Journal:

Year:

2002

Language:

english

File:

PDF, 230 KB

english, 2002

26

Fc fusion as a platform technology: potential for modulating immunogenicity

Levin, Ditza, Golding, Basil, Strome, Scott E., Sauna, Zuben E.

Journal:

Trends in Biotechnology

Year:

2015

Language:

english

File:

PDF, 1009 KB

english, 2015

27

Building better drugs: developing and regulating engineered therapeutic proteins

Kimchi-Sarfaty, Chava, Schiller, Tal, Hamasaki-Katagiri, Nobuko, Khan, Mansoor A., Yanover, Chen, Sauna, Zuben E.

Journal:

Trends in Pharmacological Sciences

Year:

2013

Language:

english

File:

PDF, 943 KB

english, 2013

28

Sinusitis In Latino Children Is Associated With Allergic Respiratory Diseases and Inversely Related To Native American Ancestry (GALA II Study)

Regan, Jennifer A., Hsu, Joy, Nguyen, Elizabeth, Roth, Lindsey, Galanter, Joshua, Oh, Sam, Eng, Celeste, Lurmann, Fred, Kumar, Rajesh, Farber, Harold J., Serebrisky, Denise, Borrell, Luisa, Sen, Sauna

Journal:

Journal of Allergy and Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 40 KB

english, 2014

29

Multidrug Resistance Protein 4 (ABCC4)-mediated ATP Hydrolysis: EFFECT OF TRANSPORT SUBSTRATES AND CHARACTERIZATION OF THE POST-HYDROLYSIS TRANSITION STATE

Sauna, Z. E., Nandigama, K., Ambudkar, S. V.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 873 KB

english, 2004

30

Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model

Levin, D., Lagassé, H. A. D., Burch, E., Strome, S., Tan, S., Jiang, H., Sauna, Z. E., Golding, B.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2017

Language:

english

File:

PDF, 601 KB

english, 2017

31

Modified aptamers as reagents to characterize recombinant human erythropoietin products

Jankowski, Wojciech, LagassÃ©, H. A. Daniel, Chang, William C., McGill, Joseph, Jankowska, Katarzyna I., Gelinas, Amy D., Janjic, Nebojsa, Sauna, Zuben E.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.69 MB

2020

32

What does a Common Channel for Electrolytes and Non-electrolytes in the Sperm Mean?

V SITARAMAM, ZUBEN E SAUNA

Journal:

Journal of Theoretical Biology

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000

33

Mapping Conformational Changes Associated with the Catalytic Cycle of Human P-Glycoprotein (ABCB1)

Bhatnagar, Jaya, Sim, Hong-May, Georgieva, Elka, Kapoor, Khyati, Chufan, Eduardo, Ohnuma, Shinobu, Borbat, Peter P., Freed, Jack H., Sauna, Zuben E., Ambudkar, Suresh V.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 51 KB

english, 2012

34

Effect of Pulp Extractives on Sizing

Rao, G. Venkoba, Murthy, N. V. S. R., Raju, P. V. Annam, Sauna, G. S. R. P.

Journal:

Journal of Wood Chemistry and Technology

Year:

1983

Language:

english

File:

PDF, 254 KB

english, 1983

35

Identification of sequence-structure RNA binding motifs for SELEX-derived aptamers

Hoinka, J., Zotenko, E., Friedman, A., Sauna, Z. E., Przytycka, T. M.

Journal:

Year:

2012

Language:

english

File:

PDF, 957 KB

english, 2012

36

Osmotic perturbations induce differential movements in the core and periphery of proteins, membranes and micelles

C.N Madhavarao, Z.E Sauna, A Srivastava, V Sitaramam

Journal:

Biophysical Chemistry

Year:

2001

Language:

english

File:

PDF, 233 KB

english, 2001

37

Effects of dicoumarol, insulin and anoxia on rat diaphragm—I. Effect on respiration, extracellular space and water content

Matilde Saunas, Jose L. R-Candela

Journal:

Biochemical Pharmacology

Year:

1973

Language:

english

File:

PDF, 580 KB

english, 1973

38

The Interaction Between Market Orientation, Industry Environment and Business Success: Evidence from an Exporting Context

Sauna Sundqvist, Kaisu Puumalainen, Risto T. Salminen, John W. Cadogan

Journal:

Australasian Marketing Journal (AMJ)

Year:

2000

Language:

english

File:

PDF, 2.77 MB

english, 2000

39

Vehicle Collision into Steel Pedestrian Bridges

Salokangas, Lauri, Sauna-Aho, Niko

Journal:

IABSE Symposium Report

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

40

Effects of dicoumarol, insulin and anoxia on rat diaphragm—II. Penetration of sugars

Matilde Saunas, Jose L. R-Candela

Journal:

Biochemical Pharmacology

Year:

1973

Language:

english

File:

PDF, 699 KB

english, 1973

41

Single-nucleotide variations defining previously unreported ADAMTS13 haplotypes are associated with differential expression and activity of the VWF-cleaving protease in a Salvadoran congenital thrombotic thrombocytopenic purpura family

Kim, Benjamin, Hing, Zachary A., Wu, Andrew, Schiller, Tal, Struble, Evi B., Liuwantara, David, Kempert, Pamela H., Broxham, Eric J., Edwards, Nathan C., Marder, Victor J., Simhadri, Vijaya L., Sauna,

Journal:

British Journal of Haematology

Year:

2014

Language:

english

File:

PDF, 80 KB

english, 2014

42

Pharmacokinetics, biodistribution and tumor localization of two anti-human B-cell chronic lymphocytic leukemia monoclonal antibodies and their F(ab)′2 fragments in a xenograft model

Zhu, Zhenping, Ghose, Tarunendu, Iles, Sauna, Yang, Chunzheng, Lee, Spencer H.S., Fernandez, Louis A., Lee, Christine L.Y.

Journal:

Year:

1994

Language:

english

File:

PDF, 5.55 MB

english, 1994

43

Inhibition of Multidrug Resistance-Linked P-Glycoprotein (ABCB1) Function by 5′-Fluorosulfonylbenzoyl 5′-Adenosine: Evidence for an ATP Analogue That Interacts with Both Drug-Substrate-and Nucleotide-Binding Sites

Ohnuma, Shinobu, Chufan, Eduardo, Nandigama, Krishnamachary, Jenkins, Lisa M. Miller, Durell, Stewart R., Appella, Ettore, Sauna, Zuben E., Ambudkar, Suresh V.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.10 MB

english, 2011

44

Correction to Comparative Metabolomics in Glycine max and Glycine soja under Salt Stress To Reveal the Phenotypes of Their Offspring

Lu, Yonghai, Lam, Honming, Pi, Erxu, Zhan, Qinglei, Tsai, Sauna, Wang, Chunmei, Kwan, Yiuwa, Ngai, Saiming

Journal:

Journal of Agricultural and Food Chemistry

Year:

2014

File:

PDF, 109 KB

2014

45

P052 Severe anemia as rare onset clinical sign of cystic fibrosis

Bongiovanni, A., Motta, M., Parisi, G.F., Papale, M., Franzonello, C., Sauna, A., Sapuppo, A., Tardino, L., Rotolo, N., Spina, M., Leonardi, S.

Journal:

Digestive and Liver Disease

Year:

2018

Language:

english

File:

PDF, 68 KB

english, 2018

46

“In vivo” administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain

A. Concas, M. P. Mascia, E. Sauna, G. Santoro, M. Serra, G. Biggio

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1991

Language:

english

File:

PDF, 500 KB

english, 1991

47

Personalized approaches to the treatment of hemophilia A and B

Simhadri, Vijaya L, Banerjee, Aditi Sengupta, Simon, Jonathan, Kimchi-Sarfaty, Chava, Sauna, Zuben E

Journal:

Personalized Medicine

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

48

P-glycoprotein: from genomics to mechanism

Ambudkar, Suresh V, Kimchi-Sarfaty, Chava, Sauna, Zuben E, Gottesman, Michael M

Journal:

Year:

2003

Language:

english

File:

PDF, 474 KB

english, 2003

49

Clinical manifestation of hemophilia A in the absence of mutations in the F8 gene that encodes FVIII: role of microRNAs

Jankowska, Katarzyna I., McGill, Joseph, Pezeshkpoor, Behnaz, Oldenburg, Johannes, Atreya, Chintamani D., Sauna, Zuben E.

Journal:

Transfusion (Wiley)

Year:

2019

Language:

english

File:

PDF, 6.89 MB

english, 2019

50

SampPick: Selection of a Cohort of Subjects Matching a Population HLA Distribution

McGill, Joseph R., Yogurtcu, Osman N., Verthelyi, Daniela, Yang, Hong, Sauna, Zuben E.

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 3.22 MB

english, 2019

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