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101

Cloning and functional characterisation of polyunsaturated fatty acid elongases of marine and freshwater teleost fish

Morris K. Agaba, Douglas R. Tocher, Xiaozhong Zheng, Cathryn A. Dickson, James R. Dick, Alan J. Teale

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 370 KB

english, 2005

102

Effect of diets enriched in Δ6 desaturated fatty acids (18:3n − 6 and 18:4n − 3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.)

Douglas R. Tocher, James R. Dick, Philip MacGlaughlin, J. Gordon Bell

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

103

Long-chain polyunsaturated fatty acid synthesis in fish: Comparative analysis of Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.) Δ6 fatty acyl desaturase gene promoters

Xiaozhong Zheng, Michael J. Leaver, Douglas R. Tocher

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 906 KB

english, 2009

104

Effects of dietary fish oil substitution by Echium oil on enterocyte and hepatocyte lipid metabolism of gilthead seabream (Sparus aurata L.)

Mercedes Díaz-López, Ma José Pérez, Nieves Guadalupe Acosta, Salvador Jerez, Roberto Dorta-Guerra, Douglas R. Tocher, Antonio Lorenzo, Covadonga Rodríguez

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

105

Biosynthesis of very long-chain fatty acids (C > 24) in Atlantic salmon: Cloning, functional characterisation, and tissue distribution of an Elovl4 elongase

Greta Carmona-Antoñanzas, Óscar Monroig, James R. Dick, Andrew Davie, Douglas R. Tocher

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

106

Delta-8 desaturation activity varies among fatty acyl desaturases of teleost fish: High activity in delta-6 desaturases of marine species

Óscar Monroig, Yuanyou Li, Douglas R. Tocher

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 858 KB

english, 2011

107

Age-related changes in mitochondrial membrane composition of rainbow trout (Oncorhynchus mykiss) heart and brain

Pedro F. Almaida-Pagán, Jorge de Costa, Pilar Mendiola, Douglas R. Tocher

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

108

Transcriptomic analyses of intestinal gene expression of juvenile Atlantic cod (Gadus morhua) fed diets with Camelina oil as replacement for fish oil

Sofia Morais, Rolf B. Edvardsen, Douglas R. Tocher, J. Gordon Bell

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 291 KB

english, 2012

109

Effects of water temperature and diets containing palm oil on fatty acid desaturation and oxidation in hepatocytes and intestinal enterocytes of rainbow trout (Oncorhynchus mykiss)

Douglas R. Tocher, Jorge Fonseca-Madrigal, James R. Dick, Wing-Keong Ng, J.Gordon Bell, Patrick J. Campbell

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 498 KB

english, 2004

110

Influence of dietary conjugated linoleic acid (CLA) on lipid and fatty acid composition in liver and flesh of Atlantic salmon (Salmo salar)

Sean R. Kennedy, Patrick J. Campbell, Allan Porter, Douglas R. Tocher

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

111

Recent developments in the essential fatty acid nutrition of fish

John Sargent, Gordon Bell, Lesley McEvoy, Douglas Tocher, Alicia Estevez

Journal:

Year:

1999

Language:

english

File:

PDF, 68 KB

english, 1999

112

Relationships between antioxidants, antioxidant enzyme activities and lipid peroxidation products during early development in Dentex dentex eggs and larvae

Gabriel Mourente, Douglas R Tocher, Esther Diaz, Amalia Grau, Elena Pastor

Journal:

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

113

Lipid nutrition of marine fish during early development: current status and future directions

John Sargent, Lesley McEvoy, Alicia Estevez, Gordon Bell, Michael Bell, James Henderson, Douglas Tocher

Journal:

Year:

1999

Language:

english

File:

PDF, 85 KB

english, 1999

114

Degradation of specific polyunsaturated fatty acids in red blood cells stored at −20°C proceeds faster in patients with schizophrenia when compared with healthy controls

Helen Fox, Brian M. Ross, Douglas Tocher, David Horrobin, Iain Glen, David St. Clair

Journal:

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

115

Stimulation of proliferation of an essential fatty acid-deficient fish cell line by C20 and C22 polyunsaturated fatty acids and effects on fatty acid composition

Douglas R. Tocher, James R. Dick, John R. Sargent

Journal:

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

116

Low C18 to C20 fatty acid elongase activity and limited conversion of stearidonic acid, 18:4(n–3), to eicosapentaenoic acid, 20:5(n–3), in a cell line from the turbot, Scophthalmus maximus

Cristina Ghioni, Douglas R Tocher, Michael V Bell, James R Dick, John R Sargent

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

1999

Language:

english

File:

PDF, 189 KB

english, 1999

117

[Biochemistry and Molecular Biology of Fishes] Metabolic biochemistry Volume 4 || Chapter 6 Glycerophospholipid metabolism

Tocher, Douglas R.

Year:

1995

Language:

english

File:

PDF, 2.82 MB

english, 1995

118

Polyunsaturated fatty acid metabolism in fish cells: differential metabolism of (n-3) and (n-6) series acids by cultured cells orginating from a freshwater teleost fish and from a marine teleost fish

Douglas R. Tocher, Janette Carr, John R. Sargent

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1989

Language:

english

File:

PDF, 672 KB

english, 1989

119

Effects of diets containing vegetable oil on expression of genes involved in highly unsaturated fatty acid biosynthesis in liver of Atlantic salmon (Salmo salar)

Xiaozhong Zheng, Douglas R. Tocher, Cathryn A. Dickson, J.Gordon Bell, Alan J. Teale

Journal:

Year:

2004

Language:

english

File:

PDF, 277 KB

english, 2004

120

Effects of exogenous monounsaturated fatty acids on fatty acid metabolism in cultured skin fibroblasts from adrenoleukodystrophy patients

Robert Wilson, Douglas R. Tocher, John R. Sargent

Journal:

Journal of the Neurological Sciences

Year:

1992

Language:

english

File:

PDF, 979 KB

english, 1992

121

Effects of weaning onto a pelleted diet on docosahexaenoic acid (22: 6 n-3) levels in brain of developing turbot (Scophthalmus maximus L.)

Gabriel Mourente, Douglas R. Tocher

Journal:

Year:

1992

Language:

english

File:

PDF, 1.15 MB

english, 1992

122

Effect of dietary digestible energy content on expression of genes of lipid metabolism and LC-PUFA biosynthesis in liver of Atlantic salmon (Salmo salar L.)

Martinez-Rubio, Laura, Wadsworth, Simon, González Vecino, Jose L., Bell, J. Gordon, Tocher, Douglas R.

Journal:

Year:

2013

Language:

english

File:

PDF, 519 KB

english, 2013

123

Effect of functional feeds on fatty acid and eicosanoid metabolism in liver and head kidney of Atlantic salmon (Salmo salar L.) with experimentally induced Heart and Skeletal Muscle Inflammation

Martinez-Rubio, Laura, Morais, Sofia, Evensen, Øystein, Wadsworth, Simon, Vecino, Jose G., Ruohonen, Kari, Bell, J. Gordon, Tocher, Douglas R.

Journal:

Fish & Shellfish Immunology

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

124

Tailoring of Atlantic Salmon ( Salmo salar L.) Flesh Lipid Composition and Sensory Quality by Replacing Fish Oil with a Vegetable Oil Blend

Torstensen, Bente E., Bell, J. Gordon, Rosenlund, Grethe, Henderson, R. James, Graff, Ingvild E., Tocher, Douglas R., Lie, Øyvind, Sargent, John R.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

125

An evolutionary perspective on Elovl5 fatty acid elongase: comparison of Northern pike and duplicated paralogs from Atlantic salmon

Greta Carmona-Antoñanzas, Douglas R Tocher, John B Taggart…

Journal:

BMC Evolutionary Biology

Year:

2013

Language:

english

File:

PDF, 431 KB

english, 2013

126

Influence of broodstock diet on somatic growth, fecundity, gonad carotenoids and larval survival of sea urchin

Carboni, Stefano, Hughes, Adam D., Atack, Tim, Tocher, Douglas R., Migaud, Herve

Journal:

Aquaculture Research

Year:

2015

Language:

english

File:

PDF, 306 KB

english, 2015

127

Functional characterisation of a Fads2 fatty acyl desaturase with Δ6/Δ8 activity and an Elovl5 with C16, C18 and C20 elongase activity in the anadromous teleost meagre (Argyrosomus regius)

Monroig, Óscar, Tocher, Douglas R, Hontoria, Francisco, Navarro, Juan C

Journal:

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

128

Fatty acid profiles during gametogenesis in sea urchin (Paracentrotus lividus): Effects of dietary inputs on gonad, egg and embryo profiles

Carboni, Stefano, Hughes, Adam D., Atack, Tim, Tocher, Douglas R., Migaud, Herve

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2013

Language:

english

File:

PDF, 398 KB

english, 2013

129

Conservation of lipid metabolic gene transcriptional regulatory networks in fish and mammals

Carmona-Antoñanzas, Greta, Tocher, Douglas R., Martinez-Rubio, Laura, Leaver, Michael J.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

130

Dietary modulation of arachidonic acid metabolism in senegalese sole (Solea Senegalensis) broodstock reared in captivity

Norambuena, Fernando, Morais, Sofia, Estévez, Alicia, Bell, J. Gordon, Tocher, Douglas R., Navarro, Juan C., Cerdà, Joan, Duncan, Neil

Journal:

Year:

2013

Language:

english

File:

PDF, 678 KB

english, 2013

131

Effect of varying dietary levels of LC-PUFA and vegetable oil sources on performance and fatty acids of Senegalese sole post larvae: Puzzling results suggest complete biosynthesis pathway from C18 PUFA to DHA

Navarro-Guillén, Carmen, Engrola, Sofia, Castanheira, Filipa, Bandarra, Narcisa, Hachero-Cruzado, Ismael, Tocher, Douglas R., Conceição, Luís E.C., Morais, Sofia

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2014

Language:

english

File:

PDF, 683 KB

english, 2014

132

Influence of dietary docosahexaenoic acid in combination with other long-chain polyunsaturated fatty acids on expression of biosynthesis genes and phospholipid fatty acid compositions in tissues of post-smolt Atlantic salmon (Salmo salar)

Betancor, Mónica B., Howarth, Fraser J.E., Glencross, Brett D., Tocher, Douglas R.

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2014

Language:

english

File:

PDF, 650 KB

english, 2014

133

miR-17 is involved in the regulation of LC-PUFA biosynthesis in vertebrates: Effects on liver expression of a fatty acyl desaturase in the marine teleost Siganus canaliculatus

Zhang, Qinghao, Xie, Dizhi, Wang, Shuqi, You, Cuihong, Monroig, Óscar, Tocher, Douglas R., Li, Yuanyou

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

134

No relationship between morphology changes and metabolism of α-linolenate and eicosapentaenoate in rainbow trout (Oncorhynchus mykiss) astroglial cells in primary culture

Tocher, Douglas R., Sargent, John R.

Journal:

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology

Year:

1993

Language:

english

File:

PDF, 2.22 MB

english, 1993

135

The effects of weaning on to a dry pellet diet on brain lipid and fatty acid compositions in post-larval gilthead sea bream (Sparus aurata L.)

Mourente, Gabriel, Tocher, Douglas R.

Journal:

Comparative Biochemistry and Physiology Part A: Physiology

Year:

1993

Language:

english

File:

PDF, 808 KB

english, 1993

136

The effect of calcium ionophore A23187 on the metabolism of arachidonic and eicosapentaenoic acids in neutrophils from a marine teleost fish rich in (n-3) polyunsaturated fatty acids

Tocher, Douglas R., Sargent, John R.

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1987

Language:

english

File:

PDF, 641 KB

english, 1987

137

Effect of polyunsaturated fatty acids on the growth of fish cells in culture

Tocher, Douglas R., Dick, James R.

Journal:

Comparative Biochemistry and Physiology Part A: Physiology

Year:

1991

Language:

english

File:

PDF, 740 KB

english, 1991

138

BRAIN WATER MEASURED BY MAGNETIC RESONANCE IMAGING

Bell, B.A., Kean, D.M., Macdonald, H.L., Barnett, G.H., Douglas, R.H.B., Smith, M.A., Mcghee, C.N.J., Miller, J.D., Tocher, J.L., Best, J.J.K.

Journal:

Year:

1987

Language:

english

File:

PDF, 569 KB

english, 1987

139

Changes in mitochondrial membrane composition and oxidative status during rapid growth, maturation and aging in zebrafish, Danio rerio

Almaida-Pagán, Pedro F., Lucas-Sánchez, Alejandro, Tocher, Douglas R.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2014

Language:

english

File:

PDF, 466 KB

english, 2014

140

Interactions between dietary docosahexaenoic acid and other long-chain polyunsaturated fatty acids on performance and fatty acid retention in post-smolt Atlantic salmon (Salmo salar)

Glencross, Brett D., Tocher, Douglas R., Matthew, Chessor, Gordon Bell, J.

Journal:

Fish Physiology and Biochemistry

Year:

2014

Language:

english

File:

PDF, 365 KB

english, 2014

141

Investigating long-chain polyunsaturated fatty acid biosynthesis in teleost fish: Functional characterization of fatty acyl desaturase (Fads2) and Elovl5 elongase in the catadromous species, Japanese eel Anguilla japonica

Wang, Shuqi, Monroig, Óscar, Tang, Guoxia, Zhang, Liang, You, Cuihong, Tocher, Douglas R., Li, Yuanyou

Journal:

Year:

2014

Language:

english

File:

PDF, 628 KB

english, 2014

142

Racemic progesterone: predicted in silico and produced in the solid state

Lancaster, Robert W., Karamertzanis, Panagiotis G., Hulme, Ashley T., Tocher, Derek A., Covey, Douglas F., Price, Sarah L.

Journal:

Chemical Communications

Year:

2006

Language:

english

File:

PDF, 294 KB

english, 2006

143

Docosahexaenoic acid biosynthesis via fatty acyl elongase and Δ4-desaturase and its modulation by dietary lipid level and fatty acid composition in a marine vertebrate

Morais, Sofia, Mourente, Gabriel, Martínez, Almudena, Gras, Noélia, Tocher, Douglas R.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2015

Language:

english

File:

PDF, 566 KB

english, 2015

144

Dynamics of fatty acid metabolism in a cell line from southern bluefin tuna (Thunnus maccoyii)

Scholefield, Andrew M., Tocher, Douglas R., Schuller, Kathryn A.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

145

Nutritional quality of salmon products available from major retailers in the UK: content and composition of n-3 long-chain PUFA

Henriques, João, Dick, James R., Tocher, Douglas R., Bell, J. Gordon

Journal:

British Journal Of Nutrition

Year:

2014

Language:

english

File:

PDF, 231 KB

english, 2014

146

Nutrigenomic profiling of transcriptional processes affected in liver and distal intestine in response to a soybean meal-induced nutritional stress in Atlantic salmon (Salmo salar)

De Santis, Christian, Bartie, Kerry L., Olsen, Rolf E., Taggart, John B., Tocher, Douglas R.

Journal:

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

147

Three Peroxisome Proliferator-Activated Receptor Isotypes from Each of Two Species of Marine Fish

Leaver, Michael J., Boukouvala, Evridiki, Antonopoulou, Efthimia, Diez, Amalia, Favre-Krey, Laurence, Ezaz, M. Tariq, Bautista, José M., Tocher, Douglas R., Krey, Grigorios

Journal:

Year:

2005

Language:

english

File:

PDF, 948 KB

english, 2005

148

Incorporation and metabolism of fatty acids by desaturation and elongation in the nematode, Panagrellus redivivus

Becker, Klaus, Dick, James, Schlechtriem, Christian, Tocher, Douglas

Journal:

Year:

2004

Language:

english

File:

PDF, 222 KB

english, 2004

149

Investigating the essential fatty acids in the common cuttlefish Sepia officinalis (Mollusca, Cephalopoda): Molecular cloning and functional characterisation of fatty acyl desaturase and elongase

Monroig, Óscar, Hontoria, Francisco, Varó, Inmaculada, Tocher, Douglas R., Navarro, Juan C.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.50 MB

english, 2016

150

Influence of dietary phospholipid on early development and performance of Atlantic salmon (Salmo salar)

Taylor, John F., Martinez-Rubio, Laura, del Pozo, Jorge, Walton, James M., Tinch, Alan E., Migaud, Herve, Tocher, Douglas R.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015