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51

Scavenging reactive oxygen species production normalizes ferroportin expression and ameliorates cellular and systemic iron disbalances in hemolytic mouse model

Tangudu, Naveen Kumar, Alan, Betuel, Vinchi, Francesca, Woerle, Katharina, Lai, Dilay, Vettorazzi, Sabine, Leopold, Kerstin, Vujic Spasic, Maja

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 6.88 MB

english, 2017

52

ChemInform Abstract: A LONG SILICON-HYDROGEN BOND OR A SHORT SILICON-HYDROGEN NONBOND? NEUTRON-DIFFRACTION STUDY OF (η5-MEC5H4)(CO)2(H)MNSIF(C6H5)2

SCHUBERT, U., ACKERMANN, K., WOERLE, B.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 92 KB

1983

53

ChemInform Abstract: Ca6LixAl23-x, Sr9Li7+xAl36-x, and Ba2Li3+xAl6-x: New Ternary Intermetallic Compounds Linking Close-Packed Metal Structures and Zintl Phases.

U. HAEUSSERMANN, M. WOERLE, R. NESPER

Journal:

Year:

1997

Language:

english

File:

PDF, 31 KB

english, 1997

54

Author response to letter from Snyder et al. regarding manuscript entitled ‘Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor, linagliptin’ by Graefe-Mody et al.

U. Graefe-Mody, C. Friedrich, A. Port, A. Ring, S. Retlich, T. Heise, A. Halabi, H.-J. Woerle

Journal:

Diabetes, Obesity and Metabolism

Year:

2012

Language:

english

File:

PDF, 445 KB

english, 2012

55

O14 La linagliptine améliore le contrôle glycémique chez les diabétiques de type 2 insuffisamment contrôlés par l’association metformine plus sulfonylurée, sans prise de poids ni hypoglycémie

D.R. Owens, R. Swallow, P. Jones, H.-J. Woerle, E. Tocque-Le-Gousse, K.A. Dugi

Journal:

Diabetes & Metabolism

Year:

2011

Language:

french

File:

PDF, 53 KB

french, 2011

56

Linagliptin monotherapy in type 2 diabetes patients for whom metformin is inappropriate: an 18-week randomized, double-blind, placebo-controlled phase III trial with a 34-week active-controlled extension

Barnett, A. H., Patel, S., Harper, R., Toorawa, R., Thiemann, S., von Eynatten, M., Woerle, H.-J.

Journal:

Diabetes, Obesity and Metabolism

Year:

2012

Language:

english

File:

PDF, 619 KB

english, 2012

57

Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials

von Eynatten, Maximilian, Gong, Yan, Emser, Angela, Woerle, Hans-Juergen

Journal:

Cardiovascular Diabetology

Year:

2013

Language:

english

File:

PDF, 562 KB

english, 2013

58

Preregistration of study design and non-inferiority margin – Authors' reply

Gallwitz, Baptist, Rosenstock, Julio, Woerle, Hans-Juergen

Journal:

Year:

2013

Language:

english

File:

PDF, 105 KB

english, 2013

59

Endogenous GLP-1 Regulates Postprandial Glycemia in Humans: Relative Contributions of Insulin, Glucagon, and Gastric Emptying

Nicolaus, Mathias, Brödl, Julia, Linke, Rainer, Woerle, Hans-Juergen, Göke, Burkhard, Schirra, Jörg

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2011

Language:

english

File:

PDF, 245 KB

english, 2011

60

Empagliflozin as adjunct to insulin in patients with type 1 diabetes: a 4-week, randomized, placebo-controlled trial (EASE-1)

Pieber, T. R., Famulla, S., Eilbracht, J., Cescutti, J., Soleymanlou, N., Johansen, O. E., Woerle, H. J., Broedl, U. C., Kaspers, S.

Journal:

Diabetes, Obesity and Metabolism

Year:

2015

Language:

english

File:

PDF, 804 KB

english, 2015

61

Effect of Empagliflozin on Mortality and Causes of Death in Patients with Type 2 Diabetes at High Cardiovascular Risk

Fitchett, David, Inzucchi, Silvio, Lachin, John, Wanner, Christoph, Mattheus, Michaela, Johansen, Odd Erik, Woerle, Hans Jurgen, Broedl, Uli C., Zinman, Bernard

Journal:

Canadian Journal of Diabetes

Year:

2016

Language:

english

File:

PDF, 71 KB

english, 2016

62

The effect of empagliflozin on muscle sympathetic nerve activity in patients with type II diabetes mellitus

Jordan, Jens, Tank, Jens, Heusser, Karsten, Heise, Tim, Wanner, Christoph, Heer, Martina, Macha, Sreeraj, Mattheus, Michaela, Lund, Søren S., Woerle, Hans J., Broedl, Uli C.

Journal:

Journal of the American Society of Hypertension

Year:

2017

Language:

english

File:

PDF, 3.50 MB

english, 2017

63

ChemInform Abstract: THE (η5-METHYLCYCLOPENTADIENYL)DICARBONYLMANGANESE RESIDUE AS PROTECTIVE GROUP IN THE MONOHALOGENATION OF DIPHENYLSILANE

SCHUBERT, U., WOERLE, B., JANDIK, P.

Journal:

Chemischer Informationsdienst

Year:

1981

File:

PDF, 131 KB

1981

64

P307 Risque cardiovasculaire avec Linagliptin chez des patients atteints de diabète de type 2 : une méta-analyse prédéterminée, prospective et adjudiquée à partir d’un vaste programme de phase III

O.E. Johansen, N. Neubacher, M. von Eynatten, S. Patel, H.J. Woerle, V. Katsadze

Journal:

Diabetes & Metabolism

Year:

2012

Language:

french

File:

PDF, 66 KB

french, 2012

65

Response Letter to D. Singh-Franco et al.

D. R. Owens, S. Del Prato, M. R. Taskinen, R. Gomis, T. Forst, H.-J. Woerle

Journal:

Diabetes, Obesity and Metabolism

Year:

2012

Language:

english

File:

PDF, 441 KB

english, 2012

66

ChemInform Abstract: Synthesis, Crystal, and Electronic Structure of the New Ternary Zintl Phase Eu 2-x Mg 2-y Ge 3 (x = 0.1; y = 0.5).

Slabon, Adam, Cuervo-Reyes, Eduardo, Kubata, Christof, Woerle, Michael, Mensing, Christian, Nesper, Reinhard

Journal:

Year:

2012

Language:

english

File:

PDF, 22 KB

english, 2012

67

Pharmacokinetics, pharmacodynamics and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in subjects with renal impairment

Macha, S., Mattheus, M., Halabi, A., Pinnetti, S., Woerle, H. J., Broedl, U. C.

Journal:

Diabetes, Obesity and Metabolism

Year:

2014

Language:

english

File:

PDF, 598 KB

english, 2014

68

Dynamic filtration––influence of different precipitation agents on the filtration performance using an inside-out filtration module

Loderer, Christian, Gahleitner, Bernhard, Woerle, Anna, Fuchs, Werner

Journal:

DESALINATION AND WATER TREATMENT

Year:

2013

Language:

english

File:

PDF, 746 KB

english, 2013

69

Biotransformation and mass balance of the SGLT2 inhibitor empagliflozin in healthy volunteers

Chen, Lin-Zhi, Jungnik, Arvid, Mao, Yanping, Philip, Elsy, Sharp, Dale, Unseld, Anna, Seman, Leo, Woerle, Hans-Jürgen, Macha, Sreeraj

Journal:

Year:

2015

Language:

english

File:

PDF, 679 KB

english, 2015

70

Kidney Disease End Points in a Pooled Analysis of Individual Patient–Level Data From a Large Clinical Trials Program of the Dipeptidyl Peptidase 4 Inhibitor Linagliptin in Type 2 Diabetes

Cooper, Mark E., Perkovic, Vlado, McGill, Janet B., Groop, Per-Henrik, Wanner, Christoph, Rosenstock, Julio, Hehnke, Uwe, Woerle, Hans-Juergen, von Eynatten, Maximilian

Journal:

American Journal of Kidney Diseases

Year:

2015

Language:

english

File:

PDF, 463 KB

english, 2015

71

Pharmacokinetics of Empagliflozin and Pioglitazone After Coadministration in Healthy Volunteers

Macha, Sreeraj, Mattheus, Michaela, Pinnetti, Sabine, Broedl, Uli C., Woerle, Hans J.

Journal:

Clinical Therapeutics

Year:

2015

Language:

english

File:

PDF, 270 KB

english, 2015

72

The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes

Cherney, David, Lund, Søren S., Perkins, Bruce A., Groop, Per-Henrik, Cooper, Mark E., Kaspers, Stefan, Pfarr, Egon, Woerle, Hans J., von Eynatten, Maximilian

Journal:

Year:

2016

Language:

english

File:

PDF, 471 KB

english, 2016

73

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors and Stroke　― Reply ―

Kaku, Kohei, Lee, Jisoo, Kaspers, Stefan, Woerle, Hans J., George, Jyothis T.

Journal:

Circulation Journal

Year:

2017

Language:

english

File:

PDF, 243 KB

english, 2017

74

[IEEE 2019 IEEE International Integrated Reliability Workshop (IIRW) - South Lake Tahoe, CA, USA (2019.10.13-2019.10.17)] 2019 IEEE International Integrated Reliability Workshop (IIRW) - Spatially-Resolved Evaluation of Interface Defect Density on Macrostepped SiO 2 /SiC using Local Deep Level Transient Spectroscopy

Hosaka, Anna, Yamasue, Kohei, Woerle, Judith, Ferro, Gabriel, Grossner, Ulrike, Camarda, Massimo, Cho, Yasuo

Year:

2019

File:

PDF, 3.82 MB

2019

75

Efficacy and safety of initial combination therapy with linagliptin and pioglitazone in patients with inadequately controlled type 2 diabetes: a randomized, double-blind, placebo-controlled study

R. Gomis, R.-M. Espadero, R. Jones, H. J. Woerle, K. A. Dugi

Journal:

Diabetes, Obesity and Metabolism

Year:

2011

Language:

english

File:

PDF, 849 KB

english, 2011

76

P308 L’efficacité et l’innocuité de la Linagliptine chez les Patients atteints de diabète de type 2 avec ou sans atteinte rénale : Résultats d’un programme global de phase 3

M. Cooper, M. von Eynatten, A. Emser, S. Patel, H.J. Woerle, V. Katsadze

Journal:

Diabetes & Metabolism

Year:

2012

Language:

french

File:

PDF, 66 KB

french, 2012

77

Empagliflozin Monotherapy in Japanese Patients with Type 2 Diabetes Mellitus: a Randomized, 12-Week, Double-Blind, Placebo-Controlled, Phase II Trial

Kadowaki, Takashi, Haneda, Masakazu, Inagaki, Nobuya, Terauchi, Yasuo, Taniguchi, Atsushi, Koiwai, Kazuki, Rattunde, Henning, Woerle, Hans J., Broedl, Uli C.

Journal:

Advances in Therapy

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

78

Effect of Renal Impairment on the Pharmacokinetics, Pharmacodynamics, and Safety of Empagliflozin, a Sodium Glucose Cotransporter 2 Inhibitor, in Japanese Patients With Type 2 Diabetes Mellitus

Sarashina, Akiko, Ueki, Kohjiro, Sasaki, Tomohiro, Tanaka, Yuko, Koiwai, Kazuki, Sakamoto, Wataru, Woerle, Hans J., Salsali, Afshin, Broedl, Uli C., Macha, Sreeraj

Journal:

Clinical Therapeutics

Year:

2014

Language:

english

File:

PDF, 258 KB

english, 2014

79

[IEEE 2013 IEEE Congress on Evolutionary Computation (CEC) - Cancun, Mexico (2013.06.20-2013.06.23)] 2013 IEEE Congress on Evolutionary Computation - Multi-objective evolutionary algorithm for variable selection in calibration problems: A case study for protein concentration prediction

de Lucena, Daniel Vitor, de Lima, Telma Woerle, da Silva Soares, Anderson, Delbem, Alexandre C. B., Filho, Arlindo Rodrigues Galvao, Coelho, Clarimar Jose, Laureano, Gustavo Teodoro

Year:

2013

Language:

english

File:

PDF, 3.04 MB

english, 2013

80

Initial combination of linagliptin and metformin compared with linagliptin monotherapy in patients with newly diagnosed type 2 diabetes and marked hyperglycaemia: a randomized, double-blind, active-controlled, parallel group, multinational clinical trial

Ross, S. A., Caballero, A. E., Del Prato, S., Gallwitz, B., Lewis-D'Agostino, D., Bailes, Z., Thiemann, S., Patel, S., Woerle, H.-J., von Eynatten, M.

Journal:

Diabetes, Obesity and Metabolism

Year:

2015

Language:

english

File:

PDF, 878 KB

english, 2015

81

Renal Impairment Has No Clinically Relevant Effect on the Long-Term Exposure of Linagliptin in Patients With Type 2 Diabetes

Friedrich, Christian, Emser, Angela, Woerle, Hans-Juergen, Graefe-Mody, Ulrike

Journal:

American Journal of Therapeutics

Year:

2013

Language:

english

File:

PDF, 113 KB

english, 2013

82

Assessing Pharmacokinetic Interactions Between the Sodium Glucose Cotransporter 2 Inhibitor Empagliflozin and Hydrochlorothiazide or Torasemide in Patients With Type 2 Diabetes Mellitus: A Randomized, Open-Label, Crossover Study

Heise, Tim, Mattheus, Michaela, Woerle, Hans J., Broedl, Uli C., Macha, Sreeraj

Journal:

Clinical Therapeutics

Year:

2015

Language:

english

File:

PDF, 267 KB

english, 2015

83

Multi-objective Genetic Algorithm for Variable Selection in Multivariate Classification Problems: A Case Study in Verification of Biodiesel Adulteration

Ribeiro, Lucas de Almeida, Soares, Anderson da Silva, Lima, Telma Woerle de, Jorge, Carlos Antônio Campos, Costa, Ronaldo Martins da, Salvini, Rogerio Lopes, Coelho, Clarimar Jośe, Federson, Fernando

Journal:

Procedia Computer Science

Year:

2015

Language:

english

File:

PDF, 386 KB

english, 2015

84

Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo

KORTING, HANS C., SCHALLER, MARTIN, JANUSCHKE, ELFRIEDE, SCHACKERT, CAROLIN, WOERLE, BIRGIT

Journal:

Journal of Medical Microbiology

Year:

2001

Language:

english

File:

PDF, 406 KB

english, 2001

85

Kinetics of Pt Silicide Formation Studied by Spectral Ellipsometry

Schwarz, R., Dittrich, A., Zhou, S. M., Hundhausen, M., Ley, L., Chen, L. Y., Woerle, D., Manke, C., Schulz, M.

Journal:

MRS Proceedings

Year:

1997

Language:

english

File:

PDF, 336 KB

english, 1997

86

Efficacy and safety of empagliflozin in patients with type 2 diabetes from Asian countries: pooled data from four phase III trials

Yoon, Kun-Ho, Nishimura, Rimei, Lee, Jisoo, Crowe, Susanne, Salsali, Afshin, Hach, Thomas, Woerle, Hans J.

Journal:

Diabetes, Obesity and Metabolism

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

87

Impact of empagliflozin added on to basal insulin in type 2 diabetes inadequately controlled on basal insulin: a 78-week randomized, double-blind, placebo-controlled trial

Rosenstock, J., Jelaska, A., Zeller, C., Kim, G., Broedl, U. C., Woerle, H. J.

Journal:

Diabetes, Obesity and Metabolism

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

88

ChemInform Abstract: Ferrocenyl Diphosphines Containing Stereogenic Phosphorus Atoms. Synthesis and Application in the Rhodium-Catalyzed Asymmetric Hydrogenation.

Francesca Maienza, Michael Woerle, Pascal Steffanut, Antonio Mezzetti, Felix Spindler

Journal:

Year:

1999

File:

PDF, 38 KB

1999

89

ChemInform Abstract: Niobium(V) Oxynitride: Synthesis, Characterization, and Feasibility as Anode Material for Rechargeable Lithium-Ion Batteries.

Xiao-Jun Wang, Frank Krumeich, Michael Woerle, Reinhard Nesper, Laurent Jantsky, Helmer Fjellvaag

Journal:

Year:

2012

Language:

english

File:

PDF, 21 KB

english, 2012

90

2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial

Baptist Gallwitz, Julio Rosenstock, Thomas Rauch, Sudipta Bhattacharya, Sanjay Patel, Maximilian von Eynatten, Klaus A Dugi, Hans-Juergen Woerle

Journal:

Year:

2012

Language:

english

File:

PDF, 289 KB

english, 2012

91

P284 L’efficacité et la sécurité d’emploi du BI 10773, un nouvel inhibiteur de SGLT-2 (Sodium Glucose cotransporteur de type 2), chez des diabétiques de type 2 insuffisamment contrôlés par la metformine

J. Rosenstock, A. Jelaska, L. Seman, S. Pinnetti, S. Hantel, H.J. Woerle, B. Gibelin

Journal:

Diabetes & Metabolism

Year:

2012

Language:

french

File:

PDF, 68 KB

french, 2012

92

P309 Efficacité et sécurité à long terme de la Linagliptine chez des patients avec le diabète de type 2 et l’insuffisance rénale sévère

S. Patel, S. Weber, A. Emser, M. von Eynatten, H.-J. Woerle, B. Gibelin, V. Katsadze

Journal:

Diabetes & Metabolism

Year:

2012

Language:

french

File:

PDF, 66 KB

french, 2012

93

Efficacy and Tolerability of Linagliptin Added to a Sulfonylurea Regimen in Patients With Inadequately Controlled Type 2 Diabetes Mellitus: An 18-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Lewin, Andrew J., Arvay, Lisa, Liu, Dacheng, Patel, Sanjay, von Eynatten, Maximilian, Woerle, Hans-Juergen

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.61 MB

english, 2012

94

Initial combination of linagliptin and metformin in patients with type 2 diabetes: efficacy and safety in a randomised, double-blind 1-year extension study

Haak, T., Meinicke, T., Jones, R., Weber, S., von Eynatten, M., Woerle, H.-J.

Journal:

International Journal of Clinical Practice

Year:

2013

Language:

english

File:

PDF, 428 KB

english, 2013

95

P329 Efficacité et tolérance de la linagliptine en association à l’insuline basale chez des patients diabétiques de type 2 avec insuffisance rénale

Mcgill, J., Yki-Jà, R.H., Garcia, S.-D., Thiemann, S., Hehnke, U., Pinnetti, S., Patel, S., Woerle, H.J.

Journal:

Diabetes & Metabolism

Year:

2015

Language:

french

File:

PDF, 82 KB

french, 2015

96

Linagliptin improves glycemic control after 1 year as add-on therapy to basal insulin in Asian patients with type 2 diabetes mellitus

Sheu, Wayne H.-H., Park, Sung Woo, Gong, Yan, Pinnetti, Sabine, Bhattacharya, Sudipta, Patel, Sanjay, Seck, Thomas, Woerle, Hans-Juergen

Journal:

Current Medical Research and Opinion

Year:

2015

Language:

english

File:

PDF, 655 KB

english, 2015

97

Renal Compensation for Impaired Hepatic Glucose Release During Hypoglycemia in Type 2 Diabetes: Further Evidence for Hepatorenal Reciprocity

Woerle, H. J., Meyer, C., Popa, E. M., Cryer, P. E., Gerich, J. E.

Journal:

Year:

2003

Language:

english

File:

PDF, 154 KB

english, 2003

98

Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients

Ferrannini, Ele, Muscelli, Elza, Frascerra, Silvia, Baldi, Simona, Mari, Andrea, Heise, Tim, Broedl, Uli C, Woerle, Hans-juergen

Journal:

Journal of Clinical Investigation

Year:

2014

Language:

english

File:

PDF, 831 KB

english, 2014

99

ChemInform Abstract: UEBER DIE UNTERSUCHUNG SYNTHETISCHER FLUESSIGKEITEN AUF DER BASIS N-SUBSTITUIERTER MELAMINE

SPENGLER, G., LINDINGER, H., WOERLE, R.

Journal:

Chemischer Informationsdienst

Year:

1972

File:

PDF, 206 KB

1972

100

P285 Linagliptine améliore le contrôle glycémique chez les patients atteints de diabète de type 2 indépendamment de la durée du diabète et de l’insulino-résistance

S. Patel, S. Weber, A. Emser, M. von Eynatten, H.-J. Woerle, B. Gibelin

Journal:

Diabetes & Metabolism

Year:

2012

Language:

french

File:

PDF, 68 KB

french, 2012

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